Petromyzon marinus (sea lamprey): 116945204 Help Entry 116945204         CDS       T09614                                  Symbol APOB Name (RefSeq) apolipoprotein B-100   KO K14462   apolipoprotein B Organism pmrn  Petromyzon marinus (sea lamprey) Pathway pmrn04977   Vitamin digestion and absorption Brite KEGG Orthology (KO) [BR:pmrn00001]  09150 Organismal Systems   09154 Digestive system    04977 Vitamin digestion and absorption     116945204 (APOB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pmrn04147]     116945204 (APOB)    00536 Glycosaminoglycan binding proteins [BR:pmrn00536]     116945204 (APOB) Exosome [BR:pmrn04147]  Exosomal proteins   Exosomal proteins of other cancer cells    116945204 (APOB) Glycosaminoglycan binding proteins [BR:pmrn00536]  Heparan sulfate / Heparin   Others    116945204 (APOB) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Vitellogenin_N Vit_open_b-sht DUF1081 VWD YqjK ApoB100_C VWA C8 Apolipoprotein Motif Other DBs NCBI-GeneID:  116945204 NCBI-ProteinID:  XP_032815375 UniProt:  A0AAJ7WZ54 LinkDB All DBs Position 23:4491874..4542859 Genome browser AA seq 5361 aa AA seqDB search MARLSPFHVALLLVLATATAQYAEDDSSEEATSTDCPKEAARFRPLRKYTYSYEAEVGSG VEGAAPNRAGFRIQCKVELEVPERCAFVLRVKDCALHEATSTGPNGQPKYSQIRGSELQQ SLSRFELGFRTSYGSVAMLFPHSDEPEAVLNVKRGIIAALMPPPTGEGDRDTRDLPSVHG GCPTEVTVTARKGIVPSEVTLTRDLRSCDSPVGKGAIASPLALVSGLTTFATSLFASTQE CAYSLDSRRKAVSEVTCTERHMFLPFSSRGKSGAVSTVKQTLKMTEQAKSNIRNFDVNEK NGRGLTYEPQATDAAGEDPQRVLSTLAEMVELGSGADNKRQAELFASLLAGLRALSNGTL FEILPRLLESSSSITLQSLPQCGTAPCYSALLQLLRSKRVPPALSGVVAYALGFHPAPCT MVVRDTLTLAQAAPTRASMLALSMVVHRHFTTHKQVGPELQDVAAFMRSQLGADCSGDED KTYLALKAAGNMGGALQAADGAVVDTLAACVGNTQLPLPVQIAAIQALRRTQLTEGTRTA LLDAYRNSRSPVQRRIAAYLALMSQPEPELLWDVLNTLPREENKQLRSYVVSHVEALRTS KGPTASALRKKLEQVISGMELPASYAYSSLKYSRRMSASRVVRLPGAEHPVTGTVQLDVI LEPSGFLPRSVVLETSLDVLGESLDVFEIGVEGQGFEAPLEALFGPKGFFPNSAMSAAFW VDGKLPEQLAAVLRKWTGVNPDQRKQNIDLPKEMLGTMQKLMQEVNLQKLPMEASAFLRV MGTELGYVRHSDIKMLIGFATMAGRGLQALPKQILSALAGGVEADLFVHYVFMDNDVTVP TGAGLPLRLASTGSLVAGAKVKASMRPGEARRASAAPSLSLEVVSSMEVLLPGGVARAGL HSATSLYHESALGVAVQATGGELRVTLTPPQKTNRLLSVGNQLRLLHRQRVETLPSIEEN REQWQSCRPLVFGVSLCQSGAYSNASYIEAAPWFPLTGATRFEISTEPADGVTEYSAIAE IYSRAGQENLQFKVQATGTGETKELGSILMLDRDRHRIQWDLDLPSCPGCLRVEVGVDDE SDARLNQGGYAASFNVSYQEQREAFLLARIRQTVTDARSLLLQYSAGVPRLDLHGNYVAR ALLGQDDRIVVNAEMTGSGPFSSASYGSEVVYDLDKVQAQWSAEASSDPKGALEALRDGL ARIDVPSPDEYRLQLQRALNAMLEGRVAQTDMTLRHIVVKGLEAMDLWIKKSTNNGNWNL SQLQRLQTQLSRGQEITIPSLSEFINIEMPHRTFVSSAVTVGYQFNKRSWTLQIPVPMGG RVTEPVRLLPRTLRTPALSIAPLGINVAPRQFTMQPVHLPGLGMVDSIPAFKVPERVTLK VPLFGELSIDAKVKSNVYNWTASAHVANIVGDEEDPSEIRVRSGVTAVCPCDMLSYVFNG YTALSHKHWSTFEIRTDNTITSQLLNLTTSYKSTADVSEGLNVKTEFTNRVATGLLTTTA NVVASATGDATQSSFAGELAASAELPRGIRAKVASSSSGTVNFRTRNHMLNGELRVDSDF HSLAATWRSDNDGSRYSMVASNDLTVGAGLVSRNRIELQSGLRTDNLAVRTELAFREENV TNVLSVMWDGRLFRMQDTLQGRLLGSSFTHASTFDAGEERASFSGQTDGLFGGVGVTSKL NAAYATGALRLSAENRAECARGRFDHMLTAGVTAEGLEVSVETNLAGAPGRAAYKASLVV DAAGAGGSANAAVTYGRVVLETSAEGSARASGLKVTANTVGRAEGSKVQHNAEGRLDGGG LALVSAYSGQILETDSSSTVNFELNRAGLSFVTKTVASYAENKVDHGCNLKVAPWSVDFT AADEVKVLGASFSNQLAAKAGFLTASVSGSASGDFLGNEVRHTYKLGYADLAGSASFDTV ANLNGGKLQNQLSLEFAGLAGKVGATTTCETPALKFSNVARGAALPYSLSLEVITDSQGS LSAYGEHMGSLSNKFFLQAEPLALVLSNEYRGSTQHDVAGGSHASALRHKLGAQVNPTEQ SVGWELTAELNDNRYVQKLEAQNDPLSVGAKLSAQSTVNLGFLDVNFQTPALTLPFLNVA RPVRSYNVISSLGLDRAVVSSPQDFSVQASVSYDKNQDVHVISIPFVESLPALYAQLRHY IRSVLDNMRYSLTRQEIQRYYQQYQRVLDEMPGKINNAIDQLELKNKVKHVQGQLLLALQ NYDPRDLSAQELMENFRHFSKNVASWVKRVLFYPLSALDSDKVKESVQLYIEQAVRRAKE FDREYGFTDTLMKAIEQLMDNVRNMDLSELTSGNRYVQEKVIQALDDLKQWLQRFDVDRV ARQIQEAIRSVDVREVLGRMEQVIFVEMQKIMEKIASYLENFMTTYRVREMVQNGKKNLM QFVENYEVSENLNIIRDTLVGLDLEYQFSAKAQRMMRDMKAIDLKGYLEKLSQAVNSISQ KLMSMDYPAFIKSLNELLKVALEHVENFDYNQFVVTANLWLQEQTAMVNNKLQEFNIPER VQQLRERVNTVSLNLFSYMQSFSMRDVEAYVSDWVSALFEIPAVRQVANRVLEYVEYIRL RMEETDIQAEMQKFWKGATASISDVARSVAEFDINAAVTDAVEQLNAMAASLDIQEVIQK ILRYLEEGVIIPRFKLFGHVFHRTEVSLRALRRMQISTYIYTPPLIVPFTSLYLPPDLVD LKTLSSIEMPTRISLPAFTFLGKFHVEPITIDFQKIKQQIIEFLDKIRNMDMATVHRAIQ DSTAQMGELTLNDIPFEKYLVVPEFRFPEIRMPEFNLPQLNLDDVKFIKMPEFQLPRIPH ETRLPALGKLNANLKVMSPFYTLTATAGLHNSTEVYGSPALRSFANAQATSMSSLLAFAV STEARLSAPRLQRLELSANAKLTHDLCGLTHSSDVTVDRSGATAQFNTQASAKSAPYTGE ASSAVTFTLNRAVTWEATGSYRHVLDVPAAGTAGSMNVRSTAKLIAQGAKLEADVVTTGE AQGMVYGTSHEGMHKTEARLRVDGAVLLLSGKVDSVEKFGSLKHEATLEVAPFDRVVYAH SGDTALTGLGRGSVQVNAKVQGLRVDVTVRHSAVGTKLTSGKMTSATTFHAEPFQLLLTS NTLGGGKLQLPLRLSAKVEVVNNFTVSLAPNAQHADWTFGGDFNQYRYLHDVSVDNNAER AGARISMSGNANLEFLRKEVSLPSVLLPYTNYRTPEVRDFRIWEHTGLGALLRTPQQTLN VTAQLQYAKNKEWHAVRLPVVPALHYAAERYRHVANAAFERYRDATLQWAREAYDDTRAM GADNLPKRFTVPGFTVPLLNMEVSPYTVELPDTSILVAQSYRTPRVYLPLVGYRVPSFEL SLPRVNLPPMKIPGALRRLSLPEISLRALPTALYLPAMGNLTYDFTFRCSAIAVAINSGV YNQSDIVGKLSASSASEHTILNGELSAAATLSRKRGVKLSTALALSHRAAQVSHSGVAVV NKRVGELTSDTTVKVDMPYLRVDFKQAVNASTRLRPHVRVRHVLSYKVTALELEADLSGR LEHNGTAEVAWPSLSLDSNFAGATQFKQSSSANAFSCKLDNMANLYMDQRGVRSALRNEA QSKASHASGLAWDINGKQEADLEMSPLRLYAIAKHMGRNQLRGAGVFSTQGTQSTEARLE FVQWELKGLAKGEASQGSSLTPKAASKQSLSLAVSTEKQQLAWTGEAQLGSVAYAHEAAL SNERARARCSVDVSLQGHAAFLKGVVLPVYGRSLWDVLKMDVTTKARDVQVLRAASSVEY TKNPNGYVLALPVMSEGNGYRVSIPEIRLRVPEFVKQIPAAIQAMLRDVFDSEVVGPPMP INIPAFRVPFIEMSLGPYTIDLDNLAALFDFPEEFTVPAFRVPLFDVYVPAYTVRLWDIT LPTVFMTQSFRVPFTSIVVSPYIIDLRNIQVPKMLRVPSFAFELPALPKIPMPQLDVTLE YVTMAEDYTVPFFQLIVPAFRVEVPSFTLPKELNIPAFSFLGLDSPRYVLRLDDVFSYVA NFELPTFTLPAVSVEVPALRLALPTAVTLPAFGSLVGSAKVQSPVYNVTCSYSSFGGEDP DALLIIDATASSTLRFLEFDVDVKSKISPKEDGREMRTQASLSHPELTVEFLEVLTFSDS DTSEMYEATIDLLSPSLTDASMRLSYGNARARMSMSSPSLGFLGFVAERQSPQVLSAQVY ARDTASPESDVQLALLTLSLNTPDILGVESHWKGGMAHDAASLVRRSAPRAARSLYSVVD KYHTEHLGLTLEEFPSRAQESLDASKENLRSAILRAREAVGPIPDRLRSLIQELLGKVGV FAEQMQLNLVTAIRSIQEGVRPLLRQLAKRASDLVARIDAGLKDGFEKASEALEVSAKWL KQTRLQIAGSSKYYTVERLFSSALQVTTEAGEAILQALHVAYRNLHFQLYHLEFREPFAG QLVKGSDLLATLESSMEYAADRAALAYQSLDVKAAYRDAYSKASSLADDTKRAYASAVNY DYAAGASRAMLSLRDTEQLRHIHQMTQEFFVLIGDVVKATLDELTRYFNGIVETARTIQR KYLEGTALDLNLKYWEVEERAVALIRTVLDYFRQMGPKYYQDGLSLVRELANELTEVASA INLDRPEKMGAKAMELLVQAKRVVERFVVATTAKLGEVSASTGERAVRLSAEARERIREA YERFAESYDGLLERASRALDSSLERYAGLARSLVEFLRRLPRAVSGALADYAVARPGRLS LRLPQGVVSWRSFDELPRLRDEAVSGINSTVAIGRQIINERLAQTRALISANLAVLEMTM ADAIPKLRQGVNDAKAIVDNALWFAMDPTVYIGLPTLDDFPPFKASAMVFADGDYMVTFD GRVVETPQLPGGRCAFLLAHDFLDQNFTLVKLQGFIALRLPTTVLYMTSAGAVSVDTPSN KVNIPYVDGTSGVRVTREGDLVLVETSAGAGVRIDTVRRTFLFELSGWYHGRTMGLLGTN DHEPTTDMMISNGYQASDTAAFFSSWEMTGASECASVRVVPSSRRQLSSPRCKHLLDKMN TSSPFNPCFKELDPSEFLSLCQKGSDICPTSTAYRMLCEQKGVDLSNPDDCARCNKKRLQ DLWMVNGAPSADVLFVIDQSNRLQQAKVKGLLQAVDESLSAQGIKDARYGLVTFGGKDSD GRAQVNAVRGEVWTSATNMKRALGGLEFTGASGTPAYDALVAAAGYDFQPEAARLVVLVA ESDQVASFLSSVDLANVDHLLKSNGVVLSVLSDYRALRKSGGAKSALVGLTGDGQPISGK GGPWAGGDDEVVPLPRGDYVKLVRSTNGAVFSVDALRTDVDAAAVGQAIAGYAGRNVAQR KECSCVRNEHGRGKVRCRYAS NT seq 16086 nt NT seq  +upstreamnt  +downstreamnt atggcacggttatcgccgttccacgtggcccttctgctggtgttggccacagcaactgca caatacgcggaagatgactcttccgaagaggcgacgtcaacagactgcccgaaggaggca gcgcgcttcaggccactccgcaagtacacctacagctacgaggccgaggtgggcagcggc gtggagggagcggcgcccaaccgagccggattccgcattcaatgcaaggtcgaactggag gtcccggaacgctgcgccttcgtgctgcgcgtgaaagactgcgcgctgcacgaagccacg tccacgggacccaacggacagccgaaatacagccagatccgcgggagcgagctgcagcag agcctgagccgattcgagctgggattccgcacctcctacggctccgtggcgatgctcttc ccgcacagcgacgagcccgaggcagtgctcaacgtcaagaggggaatcatcgcggcgctg atgccaccccctacgggggaaggagaccgcgacacgcgcgatctgccgagcgtgcacggc gggtgccccacggaggtgacggtgaccgcccgcaagggcattgtcccgtccgaggtgacc ctgacccgcgacctgcgctcgtgcgactcgcccgtgggcaagggcgccatcgcgagccca ctcgccctcgtctcgggcctgaccacgttcgccacatcgctcttcgcctcgacgcaagaa tgcgcctacagcctggacagccgtcgcaaggcggtcagcgaagtgacctgcacggagcgc cacatgttcctgcccttctccagcaggggtaaaagcggagcggtctccaccgtgaagcag acgctgaagatgaccgaacaggccaagtccaacattcgcaactttgacgtcaacgagaag aacgggcgcgggctgacgtacgagccccaggcgacagatgccgctggggaggatccgcag cgcgtgctgagcacgctggccgagatggtggagctgggctccggcgccgacaacaagcgc caggcggagctgttcgccagcctcctggccggcctgcgggcgctgtccaacgggacgctc ttcgaaatccttccacgcctgctcgagtcgtccagctccatcaccctgcagtcgctgccc cagtgtggcacggcgccgtgctacagcgcgctgctgcagctgctccgctccaaacgcgtt ccgccggcgctctccggcgtcgtggcctacgccctgggcttccacccggcgccctgcacc atggtggtccgggacacgctcacgctcgcgcaggcggcgccgacgcgcgccagcatgctc gcactcagcatggtcgtgcacaggcacttcacaacacacaagcaggttgggccggagctg caagacgtggccgccttcatgcggtcgcagctgggagccgactgttccggcgacgaagac aagacttacctggcgctcaaggctgctggcaacatgggcggtgccctccaggcggcggac ggcgctgtggtggacaccctggcagcgtgcgtggggaacacgcagctgccgctgccggtc cagatcgccgccatccaggcgttgcgccggacccagctcaccgaagggactcgcacggct ctgctggacgcctaccgcaactcgcggtcgccggtgcagcgccgcatcgccgcctacctg gccctgatgtcgcagccggagccggagctgctgtgggacgtgctgaacacgctgccgcgg gaggagaacaagcagctgcgcagctacgtggtgtcgcacgttgaggccctgcgcaccagc aagggcccgaccgcctccgcgctgcgcaagaagctggagcaggtgatatccgggatggag ctgccggcgtcgtacgcctacagctcgctcaagtactcgcgcaggatgtcggcgtcgcgc gtcgtcaggctgcccggtgcggagcatcccgtgaccggcaccgtgcagctcgacgtcatc ctggagccgagcgggttcctgccgcgctccgtcgtgctcgagacgtcgctggacgtgctg ggagagtcgctcgacgtgttcgagatcggcgtggagggccagggcttcgaggctccgctg gaggccctcttcgggcccaagggcttcttcccgaacagcgcaatgagcgccgccttctgg gtggacggcaaacttcccgagcagctggcggccgtcctgcgcaagtggacgggagtcaac cccgaccagcgcaagcagaacatcgacctgcccaaggagatgttgggcaccatgcagaag ctcatgcaggaggtgaacctccagaagctgcccatggaggcgtcggcgttcctgcgcgtc atgggcacggagctcggctacgtgcggcacagcgacatcaagatgctcatcggcttcgcc accatggccggccgcgggctccaggccctgcccaagcagatcctgagcgcgctggcgggc ggcgtggaggccgacctgttcgtgcactacgtgttcatggacaacgacgtgacggtgccc acgggcgccggcctgcccctccgcctcgccagcaccggaagcctggtcgccggcgccaaa gtcaaggcctcgatgcgccccggagaggcgaggcgagcctccgccgccccgtcgctctcg ctggaggtggtgtcctccatggaggtgctgctgcccggcggcgtggcgcgcgccggcctg cactcggccaccagcctctaccacgagtcggcgctcggcgtggcagtgcaggccacgggc ggggagctccgcgtgacgctcacgccgccgcagaagaccaaccgcctcctgagcgtcggg aaccagctgaggctgctgcaccgacagagggtggagacactgccgagcatcgaggagaac cgcgagcagtggcagtcgtgccggccgctcgtgttcggcgtgtcgctgtgccagagcggt gcctactccaacgccagctacatcgaggctgcgccctggttcccgctcaccggcgccacc aggtttgagatctcgacagagcccgcggacggtgtgactgagtactccgccatcgctgag atctactcgcgggccggacaagagaacctgcagttcaaggtgcaggccacaggcacggga gagacgaaggagcttgggagcatcctgatgctcgaccgtgaccgccaccgcatccaatgg gacctggacctgccgagctgccccggctgcctcagggtggaagtgggcgtcgacgacgag tcggacgcccgcctcaaccagggtggttacgcggcctccttcaacgtgagctaccaggag cagcgggaggccttcctgctcgctcggatcaggcagacggtgacggacgctcgcagcctg ctcttgcagtactccgccggggtgccgcgcctcgacctccatggcaactatgtggcgagg gcgctcctcggccaggacgaccgcatcgtcgtcaacgccgagatgacaggatcaggccct ttctcctccgcctcttacggaagcgaggtggtctacgacctcgacaaggtgcaggcccag tggagcgcggaggcatcgtcggacccgaagggcgccttggaggccctgcgcgatggcctg gcacgcatcgacgtgccgtcccccgatgagtaccgcctgcagctgcagagggcgctcaac gccatgctggagggccgcgtggcgcagaccgatatgacgctgcggcacattgtcgtcaag ggcctcgaggccatggacctgtggataaagaagtcgacaaacaacggcaactggaacctc tcgcagctgcagcggctgcagacgcagctgtcacggggccaggagatcactatcccctcg ctcagcgagttcatcaacatcgaaatgccccacaggaccttcgtgtcgagcgccgtaacc gtgggctaccaattcaacaagcggtcgtggacgctgcagatcccggtgcccatgggtggg cgcgtgaccgagccagtgcggctgctgcctcgcacgctccgcacgccggcgctgagcatc gctcctctcggcatcaacgtggcgccacggcagttcaccatgcagcccgtccacctgccc ggcctaggcatggtcgactccatcccggccttcaaggtccccgagcgtgtcacactcaag gtgccgctgttcggcgagctgagcatcgatgccaaggtgaagagcaatgtgtacaactgg acggcgagtgcgcacgtcgccaacatcgtgggcgacgaggaggacccctccgagatccgg gtgcgctccggcgtaacggccgtgtgcccctgcgacatgctgtcgtacgtcttcaacggc tacacggcactgtcacacaagcactggagcacgtttgagatccgcacggacaacaccatc accagccagctgctgaacctgaccaccagctacaagagcaccgcggacgtgagcgagggc ctgaacgtcaagaccgagttcaccaaccgcgtcgccaccggcctgctgaccaccaccgcc aacgtcgtcgcctccgcgacgggcgatgccacccagtcgtccttcgccggcgagctggcc gccagcgccgaactgcctaggggcatccgcgccaaggtggcatcgtcgtcgtcgggcacc gtcaacttccggacacgcaaccacatgctcaatggcgagctccgtgtcgactctgacttc cactcgctggcggcgacctggcggagcgacaacgacgggtcgcgctactcgatggtggcg tcgaacgatctgaccgtcggtgcgggcctcgtgtcacgcaaccgcattgagctgcaatcg gggctgcgcacagacaacctggccgtgcgcacggaactggccttccgtgaggagaacgtc accaacgtgctgagcgtgatgtgggacggccgcttgttccgtatgcaggacacgctccag ggccgcctgctgggctcctcctttacacacgcatccacctttgatgcgggcgaggaacgg gcatcgttctccgggcagacggacgggcttttcggcggcgtaggcgtgacgagcaagctg aacgccgcgtatgccaccggcgccctcagactcagcgcggagaacagggccgagtgcgcg cgcggacgcttcgaccacatgctcacggccggcgtgacggccgagggcctggaagtgtcg gtggagacgaacctcgcgggcgcgcccggccgcgccgcctacaaggcatcgctcgtcgtg gacgcggccggcgccgggggcagcgccaacgccgcggtaacgtacggccgtgtcgtgctg gagacctctgcggagggcagcgcccgtgcgtcgggcctcaaggtcaccgcgaacacagtg ggacgggcggagggcagcaaggtgcagcacaacgcagaggggaggctcgacggaggcggc ctggccctcgtcagcgcctactctgggcagatactggagacggactcgagcagcacggtc aacttcgagctgaacagggcaggcctgagcttcgtcaccaagaccgtggcctcctacgcc gagaacaaggtcgaccacggctgtaacctcaaggtcgcaccgtggtccgtcgacttcacc gccgccgacgaggtaaaggtcctcggcgcctccttctccaaccagttggcggccaaggcc ggcttcctcactgcgtcggtgagcggttccgcgtccggcgacttccttggcaatgaggtg cggcacacatacaagctgggctacgccgacctggccggctcggcctccttcgacaccgtc gcgaacctcaatggcggcaagctgcagaaccagctcagtctggagttcgccgggctcgct ggcaaggtgggcgcgaccacgacgtgcgaaacgccggcgctcaagttctcgaacgtggcg cgcggggcggcgctgccgtactcgctcagcctcgaggtcatcaccgactcccagggcagc ctcagcgcctacggcgagcacatgggcagcctgtccaacaagttcttcttgcaggccgag ccgctcgcgctggtgctctccaacgagtaccgtgggtcgacgcagcatgacgtcgcgggc ggcagccacgcatcggcgctgcgccacaagctgggcgcgcaggtgaacccgacggagcag agtgtcggctgggagctgacggccgagcttaacgacaaccggtacgtgcagaagctggag gcgcagaacgacccgctcagcgtgggcgccaagctcagcgcgcagtcgacggtcaacctg ggcttcctcgacgtcaacttccagacgcctgcgctgacgctgccattcctcaacgtcgcg cggcccgtccgaagctacaacgtcatctccagcctcggcctggaccgcgctgtcgtcagc agcccacaggacttcagcgtgcaggcgtcagtgagctacgacaagaaccaggatgtccac gtcatcagcatcccgttcgtggagagcctgcccgcactctacgcgcagctgcgccattac atccgctccgtcctggacaacatgaggtactcactgacgcgtcaggagatccagcgttac taccagcagtatcagagggtgctggatgagatgccgggcaagattaacaatgccattgac cagctggaactgaagaacaaggtgaagcatgtgcaggggcagctcctgctggccctccag aactacgacccccgtgacctttccgcccaagaactgatggaaaacttccgtcacttctca aaaaacgtggcatcctgggtcaagagagtgctcttctacccactgtccgcactcgacagc gacaaagtgaaggaaagcgtccagttgtacatcgagcaggcagtacggagggctaaggag ttcgatcgcgagtacgggttcacggacaccctgatgaaggccatcgagcagctgatggac aacgtcaggaacatggacctctccgaactgacgagcggaaacagatacgtgcaggaaaag gtgatccaggctctcgatgacctcaagcagtggctgcagcggttcgacgtcgatcgggtg gcacggcagatccaggaggcgatcagatcagtcgacgtgcgtgaagtcctaggccgaatg gagcaagtgatcttcgtggagatgcagaaaattatggagaagatcgccagctacctggag aacttcatgaccacgtacagggtgcgggagatggtgcagaatggcaagaagaatttgatg cagtttgtcgagaactacgaggtttctgagaatctgaacatcatcagggacactctggtg gggctagatttagaatatcagtttagtgcgaaggcccagaggatgatgcgtgacatgaag gccatcgatttgaagggctacctcgagaagctgagccaggcggtcaacagcatcagccag aagctcatgtccatggactacccggctttcatcaagagtctcaacgagctcctgaaggtt gccctggagcatgtcgagaactttgactataaccagttcgtggtcacggccaacttatgg cttcaggagcagacggcgatggtgaacaacaaactccaggagttcaacatccccgagagg gtgcagcaactgagagagcgagtgaacacggtgtccttgaacctcttcagctacatgcaa tcgttctccatgcgtgacgtggaggcctatgtctctgactgggtctcggcgctcttcgag atacccgctgttcgccaggtggccaaccgggtcctggagtacgtcgagtacatccgtctt aggatggaggagaccgacatccaagctgagatgcagaagttctggaagggagccaccgcc tccatctcggacgtcgcccgctccgtcgccgagttcgacatcaatgcggcggtgacagat gcggtcgagcagctcaacgccatggccgcgagcctcgacatccaggaggtcatccagaaa atcctccgctacctcgaggaaggcgtcatcatcccacggttcaagctctttggacatgtg ttccacaggaccgaagtaagcctcagggccctgcgcaggatgcagatctcgacatatatc tacacgccgccgctcatcgtgccattcaccagcctttacctcccaccggacctcgtcgac ctgaagacgctgtcttccatcgagatgccgactcgcatctccttaccggccttcaccttc ctgggcaagttccatgttgagccgatcaccatcgactttcagaagatcaagcagcaaatc atcgagttcctcgacaaaatccgcaacatggacatggccacggtccacagggcaatccag gactccacagcacagatgggagaactgacgctcaatgacatccccttcgagaagtacctg gtggtaccagaattccgtttccctgaaatccgtatgccagagtttaacttgccccagctg aacctggacgacgtcaagttcatcaagatgcccgagttccagctgccgcgcatccctcac gaaacgcggctgccagcgctgggcaagctgaacgccaacctcaaggtgatgtcgccattc tacacgctcacggcgaccgcgggactccacaactccacagaagtgtacggctcgccggcc ctgcgctcgttcgccaacgcgcaggctacatccatgtcgagcctccttgcgttcgccgtg agcacggaggcacggctctctgcaccgcggctccagcggctggagctgagcgccaacgcc aagctgacgcatgacctctgcggcctgacgcacagctcggacgtgaccgtcgaccgctcg ggagcgacggcccagttcaacacgcaggcgtcggctaagtcggcgccctacaccggcgag gcgagctccgcggtgaccttcacgctgaaccgcgccgtcacctgggaggcgacgggcagc taccgccatgtcctggacgtgcccgcggcgggcaccgccggctcgatgaatgtgcggagc acggcgaagctcatagcgcagggggcgaagctggaggcggacgtggtgacgacgggcgag gcgcagggcatggtgtatggcacatcccacgagggcatgcacaagacagaggcgcggctg cgcgtcgatggcgcggtgctactgctctccggcaaggtggactcggtggaaaagtttggc tcgctcaagcacgaggcgaccctcgaggtggcgccattcgaccgcgtggtgtacgcacac agcggcgacactgcactgactggcctggggcgtggcagcgtgcaggtgaacgccaaggtg cagggcctgcgggtcgacgtgaccgtccgccactcggccgtgggcaccaagctgacatcc ggcaagatgacgagcgcgacgacgttccatgctgagccattccagctgctgctcacctcc aatacgttgggcggtgggaagctgcagctgccgctgcgcctctccgctaaggtcgaggtg gtcaacaacttcacggtgtcgctggcaccgaacgcgcagcacgctgactggactttcggc ggcgacttcaaccagtaccgctacctccacgatgtgtcggtggacaacaacgctgagcgc gcaggggcacgcatctccatgagtggcaatgccaacctggagttcctccgcaaagaggtg agcctcccgtccgtcctcctgccgtacaccaactaccgcacgcccgaggtgcgcgacttc cggatctgggagcacacaggcctgggggcgctgcttaggacgccgcagcaaacgcttaat gtgactgcgcagctgcagtacgccaagaacaaggagtggcatgcggtgcgcctgccggtc gtgccagcgcttcactatgccgccgagcgctaccgccacgttgccaacgcggcatttgag cgctaccgcgacgcgacgctgcaatgggcacgcgaagcctacgatgacacgcgcgcgatg ggcgccgacaacctgccgaagcggttcaccgtgccaggcttcaccgtgccactgctcaac atggaggtgtcaccttacacggtggagctcccggacacgagcatcctggtcgcgcagtca taccgcaccccgcgtgtctacctgcctctcgtcggctaccgcgtgccatccttcgagctg tcgctgcccagggtgaacctacctccgatgaagatccccggggcactacgccggctatcc ctaccggagatcagcctgcgcgcgctgccgacggcgctgtacctgccggcaatgggcaac ctgacgtacgacttcaccttcaggtgctctgccatcgccgtcgccatcaactcaggcgtg tacaaccagagcgacatcgtcggcaagctgtcggcatcgtccgcgtcggagcacaccatc ctgaacggcgagctgagcgccgcggcgacgctgtcgcgtaagcgcggcgtcaagctatcg acggcactcgcgctctcccaccgcgcggcacaggtgtcccacagcggcgtcgccgtggtg aataagcgcgtcggcgagctcacatctgacacaacggtgaaggtggacatgccgtacctg cgcgtcgacttcaagcaggcggtgaatgctagcacgaggctgcggccacatgtgcgcgtg cgccacgtgctctcctacaaggtgacggcgctcgagctggaggcggacctgagtggcagg ctggagcacaatggcacggcggaggtggcgtggcccagcctctcgctcgactcgaacttt gccggcgcgacgcagttcaagcagagctcgtcagcgaacgccttctcctgcaagttggac aacatggccaacctgtacatggaccagcgcggcgtgcgctcagccctgcgcaacgaggcg cagagcaaggcgtcgcacgcctcgggactcgcgtgggacatcaacggcaagcaggaagct gacctggagatgtcgccgctgcggctctacgccatcgctaagcacatggggcgcaaccag ctgcgcggcgccggcgtcttcagcacgcagggaacgcagagcaccgaggcgcgtctcgag ttcgtgcagtgggagctcaagggcctcgccaagggcgaggcaagccagggcagcagcctg acgcccaaggccgcctccaagcagtccctgagcctggccgtgagcacagagaagcagcag ctggcgtggacgggcgaggcacagctgggcagcgtcgcatacgcacacgaggcggcgctc tccaatgagcgtgcacgcgcacgctgcagcgtcgacgtgtcactgcagggccacgccgcc tttctcaagggtgtcgtgctgcccgtgtacggccgcagcctgtgggatgtgctcaagatg gacgtgacgacaaaggcccgtgacgtgcaggtgctccgggccgcctcgtcggtggagtac accaagaaccccaacggctacgtgctggcactgcctgtgatgtccgagggcaacggctac agggtcagcatcccggagattcgcctgagggtgcccgagttcgtaaagcagatcccggcg gccatccaggcgatgctgagggacgtgttcgacagtgaagtcgtcggaccgcccatgccc atcaacatcccggcgttccgcgtgccgttcatcgagatgtcacttgggccatacacgatc gacctcgacaacctggcggcgctgttcgacttccccgaggaattcacggtgcccgcattc cgcgtgcctctctttgacgtgtatgttcccgcgtacacggtgcgcctgtgggacatcacc ttgcccactgtgttcatgacacagtcattccgagtgccattcactagcatcgtggtatca ccgtacataattgacctgcgcaacatccaggtgccgaagatgctccgagtgccctccttt gcgttcgaattacccgcgctgcccaaaataccgatgccccagctggacgtgactctcgag tacgtgaccatggcggaggactacacggtgcccttcttccagctcatcgtgcccgccttc cgtgtggaagtcccgagcttcacgttgcccaaggagctcaacatcccagccttctcgttc ctcggcctggactccccacgctacgtgctcaggcttgacgacgtgttttcgtacgtcgcc aacttcgagctgccaaccttcacgctgccagccgtgagcgtggaggtgccggccctgcgg ctggcactgcccacggcggtgacgctgccggcgttcggcagcctcgtcggcagcgccaag gtgcagtcacccgtctacaacgtgacgtgctcgtacagctcgttcggcggagaggacccc gacgcattgctcatcatcgacgccacggccagctccacgctgcgcttcctggaattcgac gtggatgtcaagtccaagatctcacccaaggaggacggcagagagatgagaactcaagca agcctctcccaccctgagctcaccgtagagttcctggaagtcctgaccttctctgacagc gacaccagtgagatgtacgaggcgaccatcgatttgctgagcccctctctgacggacgcg agcatgcgcttgagctacggcaacgcgcgagcgcgcatgtccatgtcatcgccctcgctc ggcttcctgggcttcgtggccgaaaggcagagcccgcaggtgctgagtgcgcaggtgtac gcccgtgacacggcgtcgccggagtcggacgtgcagctggcgctgctgacgctgtcgctg aacacccccgacatcctgggcgtggagtcgcactggaaggggggcatggctcacgacgcc gcctctctggtgcgccgcagcgccccacgtgccgcccgcagcctctacagcgtcgtcgac aagtaccacacggagcacctgggactcacgttggaggagttcccatcacgggcacaggag tcgctcgacgcctccaaggaaaatctgcgctcggcgatcctcagggccagggaagcggtg gggcccattcctgatagactacgcagcctcatccaggagctcttgggcaaggtgggggtc ttcgccgagcagatgcaactcaacctcgtgaccgccatccgcagcatccaggagggcgtc cgcccgttgcttcggcagctggctaagagggcgtcggacctcgtcgcgaggatcgacgca ggcctgaaggacggcttcgagaaggccagtgaagccctggaggtctccgccaagtggctg aagcagacgcggcttcagatcgccggctccagcaagtactacacggtggagcgcctcttc agctccgcgctgcaggtcaccactgaagccggggaagccatcctccaggcactgcatgtg gcataccgcaacctgcacttccagttgtaccacctcgagttccgcgagccattcgcgggc caactggtgaagggctccgacctgctggcgacattggaaagctccatggaatacgcggcg gaccgcgccgcgctcgcctaccagagcctggatgtgaaggccgcgtaccgcgacgcttac tccaaggcgagctccctcgcggacgacacgaagcgtgcgtacgcctctgccgtcaactac gactatgccgccggcgcctcaagggccatgctgagcctgcgcgatacggaacagctgcgc cacatccaccagatgacgcaggagttcttcgtcttgatcggcgacgtcgtgaaggcgacg ctcgacgagctcacccgttatttcaacggcatcgtggaaaccgcccgcaccattcagcgc aagtacctcgagggcaccgcactggacttgaacctcaagtactgggaggtggaggagcgc gcggtggcgctcatccggaccgtcctcgactacttccgccagatgggacccaagtactac caggacggcctgtcgctggtgcgcgagctggcaaacgagctgaccgaggtcgccagcgcg atcaacctggaccgcccggagaagatgggcgccaaggcgatggagctgttggtgcaggcc aagcgcgtggttgagcgcttcgtcgtggccaccacggccaagctgggcgaggtgtcggcg agcaccggcgagcgggcggtgcggctctcggccgaggcgcgcgagcgaatccgggaggcg tacgagcgcttcgctgagtcctacgacgggctgctggagcgggcgtcgcgagccctcgac tcgtcgctcgagcgctacgccggcctcgcccgctcgctcgtcgagttcctgcgccggctg ccgcgcgccgtctcgggcgccctcgccgactacgcggtggcgcggccgggccgcctgtcg ctccggctgccccagggcgtcgtgtcgtggcgctcgttcgacgagctgccccgcctcagg gacgaggcggtgagcggcatcaacagcacggtggccatcgggcggcagatcatcaacgag cggctggcgcagacgcgcgcgctcatcagcgccaacctggccgtcctcgagatgaccatg gcggacgccatccccaagctgcgccagggagtgaacgatgcgaaggcgatcgttgacaac gcgctgtggttcgcgatggaccccaccgtctacataggcctgcccacgctggacgacttt cccccgttcaaagcgtcggccatggtctttgcggacggcgactacatggtaacgttcgac ggccgcgtcgtcgagacccctcagctgccgggcggccgctgcgccttcctgctggcgcac gacttcctcgaccagaacttcaccctcgtcaagctgcagggcttcatcgccctgcgcctg ccgaccaccgtcctctacatgacctccgccggcgccgtctccgtcgacacgccgtccaac aaggtcaacatcccgtacgtcgacgggacgtccggcgtgagagtcacccgcgagggcgac ctcgtgctggtggagacgagcgccggggcgggcgtgcgtatcgacacggtgcgccgcacc ttcctcttcgagctcagcggctggtaccacgggcgcaccatgggcctgttgggcaccaac gaccacgagccgaccaccgacatgatgatctcgaacgggtaccaggcatcggacacggcg gcgttcttctcctcgtgggagatgacgggagcgagtgagtgtgcctcggtgcgcgtcgtc ccatcctctcgccggcagctttcctcgccacggtgcaaacacctcctggacaagatgaac acgagctctccgttcaacccctgtttcaaagagctggatccatcagagttcctgagcctg tgccagaagggcagcgacatctgccccacttccaccgcctaccgcatgctctgtgagcag aagggcgtcgacctctcaaacccggatgactgcgctcgctgcaacaagaagaggctgcag gacctgtggatggtaaatggcgcgcccagcgcagacgtgctgttcgtgatcgaccagagc aacaggctgcagcaggccaaggtcaaggggctgctgcaggcagtggatgaaagcctctcc gcgcagggcatcaaggacgcgcgctacggcctggtgacgttcggtggcaaagatagcgac gggcgggcccaggtgaacgcggtgcgcggcgaggtgtggacctccgcgaccaacatgaag agggccctcggcggcctggagttcacgggggccagcggcacgccggcgtacgacgcgctc gtggcggccgccggatacgacttccagcccgaggcggcgcgcctcgtggtgctcgtggcc gagtcggaccaggtggcatccttcctgtcgtccgtggacctcgccaacgtcgaccacctg ctcaagagcaacggcgtcgtgctgagcgtgctcagcgactaccgcgcgctccgcaagtcc ggtggggccaagtcggcgctcgtgggcctgaccggcgacgggcagccaatctcgggcaag ggcggcccgtgggcgggcggcgatgacgaggtggtgccgctgccccgcggcgactacgtc aagctcgtccgctccaccaacggagccgtgttcagcgtggacgcactgcgcaccgacgtg gacgccgcggccgtgggccaggcgatcgccggctacgcgggccgcaacgtggcgcagcgc aaggagtgctcgtgcgtacgcaacgagcacggccgcggcaaggtgcggtgccgctacgcg tcgtaa

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