Petromyzon marinus (sea lamprey): 116947305
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Entry
116947305 CDS
T09614
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pmrn
Petromyzon marinus (sea lamprey)
Pathway
pmrn00280
Valine, leucine and isoleucine degradation
pmrn00640
Propanoate metabolism
pmrn00785
Lipoic acid metabolism
pmrn01100
Metabolic pathways
pmrn01210
2-Oxocarboxylic acid metabolism
Module
pmrn_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pmrn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
116947305 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
116947305 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
116947305 (BCKDHA)
Enzymes [BR:
pmrn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
116947305 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
116947305
NCBI-ProteinID:
XP_032818769
UniProt:
A0AAJ7TJ02
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Position
29:complement(8880428..8890629)
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AA seq
442 aa
AA seq
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MALHRSLRSLLPLPLRIARPSLRSLPPRPGKRLLSVSCARRQDLDDKPLFPGASAEYSDT
MEFIQPNVIAGIPVYRVMDRQGQIINPKEDPKLDKETVLKMYKKMTLLNTMDRILYESQR
QGRISFYMTNYGEEGTHMGSAAALEPHDLVFGQYREAGVLMWRDFPLDMFMSQCYGNVDD
PGKGRQMPVHYGSNELNFVTISSPLATQIPQAVGAAYAYKRANNDRVVICYFGEGAASEG
DAHAGFNFSATLECPVIFFCRNNGYAISTPTDEQYRGDGIAARGPGYGILSIRVDGNDVF
AVYNATREARRRAVSENQPTLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRL
RNYMLRESMWNDSLEKDWRKQSRKLVLEAFEKAEKRLKPSPSELFHDVYKEMTPHIQRQM
DEMRRHVKIYAEHYPMDKFDKF
NT seq
1329 nt
NT seq
+upstream
nt +downstream
nt
atggcgcttcaccgcagcctccgatccctgctgccgctgccgctcaggatcgctcgcccg
agcctcaggagtctcccgccgcgaccggggaagcgattattatccgtctcctgcgcccgc
cgtcaggatctggacgacaaaccgcttttcccgggagcgtcggccgagtactcggacacc
atggagttcatccagcccaacgtgatcgctggcatccccgtctaccgcgttatggaccgc
cagggccagatcatcaaccccaaggaggaccccaagctggacaaggaaacggtgctgaag
atgtacaagaagatgaccctgctcaacacgatggaccgcatcctgtacgagtcgcagcgg
cagggacgcatctccttctacatgaccaactacggcgaggagggcacccacatgggcagc
gctgccgcccttgagcctcacgacctcgtgttcgggcagtaccgggaggccggtgttctg
atgtggcgagacttcccgctcgacatgttcatgtcgcagtgctacggcaacgtggatgat
ccgggcaaggggcggcagatgcccgtccactacggatcgaacgagctcaacttcgtcacc
atctcctccccgcttgccacgcagatcccgcaggccgtgggtgccgcctatgcctacaag
cgcgccaacaacgaccgcgtggtgatctgctacttcggggagggcgcggcgagcgagggc
gatgcccacgccggattcaacttctccgccacgctcgagtgccccgtcatcttcttctgc
cgcaacaacggctacgcgatctccacccccaccgacgagcagtaccgcggagacggcatc
gcggcgcggggcccaggctacgggatcctgtcgatccgcgtggacggcaacgatgtgttc
gccgtgtacaacgccacgcgggaggcacggaggcgcgcagtcagcgagaaccagcccacg
ctcatcgaggccatgacctaccggatcgggcaccacagcacgagcgacgacagctcagcg
taccgctcggtggacgaggtcaactactgggacaagcaggaccacccgatctcgcgactc
cgcaactacatgctccgcgagagcatgtggaacgactcgctggagaaggactggcgcaag
cagtcgcgcaagctggtcctggaggcgttcgagaaggcggagaagcgactcaagccgagc
ccctcggagctattccacgacgtgtacaaggagatgacgccgcacatccagcggcagatg
gatgagatgagacgccacgtcaaaatctacgcagagcactaccccatggacaagtttgac
aagttctga
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