Pasteurella multocida subsp. multocida Pm70: PM0113
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Entry
PM0113 CDS
T00046
Symbol
thrA
Name
(GenBank) ThrA
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pmu
Pasteurella multocida subsp. multocida Pm70
Pathway
pmu00260
Glycine, serine and threonine metabolism
pmu00261
Monobactam biosynthesis
pmu00270
Cysteine and methionine metabolism
pmu00300
Lysine biosynthesis
pmu01100
Metabolic pathways
pmu01110
Biosynthesis of secondary metabolites
pmu01120
Microbial metabolism in diverse environments
pmu01230
Biosynthesis of amino acids
Module
pmu_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pmu_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pmu_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
PM0113 (thrA)
00270 Cysteine and methionine metabolism
PM0113 (thrA)
00300 Lysine biosynthesis
PM0113 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
PM0113 (thrA)
Enzymes [BR:
pmu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
PM0113 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
PM0113 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF1131
Motif
Other DBs
NCBI-ProteinID:
AAK02197
UniProt:
Q9CPD4
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All DBs
Position
137444..139891
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AA seq
815 aa
AA seq
DB search
MRVLKFGGTSLANPERFSQAAQLIEKAHFEEQAAGVLSAPAKITNHLVALSEKASLNQPT
DANFNEAIEIFYHIIHGLHAENNRFDLEGTKALIDTEFAQISQLLEEIRQQGFVSDAVKA
TIDCRGEKLSIAMMKAWFEARGYDVTVIDPVEKLLAHGSYLESSVDIEESTKRVDAKSIP
TKNVVLMAGFTAGNEKGELVLLGRNGSDYSAACLAACLGASACEIWTDVDGVFTCDPRLV
PDARLLPSLSYREAMELSYFGAKVIHPRTIGPLVQTNIPCLIKNTGNPSAPGSIIDGNIQ
SEQLQVKGITNLDNVAMFNVSGPGMQGMVGMASRVFSAMSNAGVSVILITQSSSEYSISF
CVPAKSVEVAKQALEKEFEQELKANDLEPIDVIRDLSIISVVGDGMKQAKGIAARFFSAL
AQANISIVAIAQGSSERSISAVVALNKAIEAVKATHQALFNNKKVVDVFLVGVGGVGGEL
IEQIKHQKSYLAKKDIEIRVCAIANSNKMLLKADGLNLENWQADLETATQPSDFDVLLSF
IKLHHVVNPVFVDCTSADSVAGLYVRALGEGFHVVTPNKKANTRELAYYNALRESARNNQ
RKFLYDTNVGAGLPVIENLQNLLAAGDEVVKFSGVLSGSLSFIFGELENGLTLSEATALA
REKGFTEPDPRDDLSGQDVARKLLILARETGAQLELTDIEVESVLPAGFAEGKTTQEFMA
MLPQLDAEFSQRVANAKAEGKVLRYVGQIENNSCKVSVLEVDADDPLYKVKNGENALAFY
TRYYQPIPLLLRGYGAGNSVTAAGIFADILRTLQH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtactaaaattcggggggacgtctttagccaatccagagcgtttttcgcaggcg
gcacagcttatcgaaaaagcccattttgaagaacaagccgctggcgtgttatcagcccct
gcaaaaattaccaaccatcttgtcgccctttctgaaaaagccagtttaaatcaacctacc
gatgccaatttcaatgaagctattgagattttttatcacattattcatggtttacacgca
gaaaataatcgttttgatctagaagggacaaaagctttaattgataccgagtttgcacaa
atcagccagttgttggaagaaattcgtcaacaaggttttgtgtcggatgcggttaaagcc
acgattgattgtcgtggtgaaaaactgtctattgcgatgatgaaggcatggtttgaagct
cgcggttatgacgtgactgtgattgatccagtcgaaaaattattagcacacgggagctat
ttagagtcttcagtggatattgaagaatcgacaaaacgcgtagatgccaagtcaattcca
accaaaaatgtagtgttaatggcaggctttaccgcaggtaatgaaaaaggtgagctcgtt
ttactcgggcgtaatggttccgattattctgctgcttgtttagccgcttgtttgggcgca
agtgcttgtgaaatttggaccgatgtagatggggtctttacctgtgatccgcgtttggta
ccagatgctcgcttattgccaagcttgtcttatcgcgaagcgatggaattgtcttatttc
ggtgcaaaagtgattcatccacgcacgattggaccattagtacaaactaatattccttgc
ttaattaaaaatacgggcaatccttctgcaccgggttcgattattgatggcaacattcaa
tctgaacagttgcaagtaaaagggattactaatttagataatgtggcgatgtttaacgtg
tctggtcctgggatgcaggggatggtgggcatggcgtcacgtgttttctctgccatgtca
aatgcaggcgtttcggtgattttaattacgcaatcttcctcggaatacagtatcagtttc
tgtgtaccagccaaatcagttgaggtagcaaaacaggcgttagagaaagaatttgagcaa
gaattaaaagctaatgatcttgaaccaattgatgtaattcgtgacttatccattatttcg
gtagtgggtgatggcatgaaacaagccaaagggattgccgcacgtttcttctcagccctt
gcccaagcgaacatcagtattgttgctattgcacagggttcctctgagcgttcaatttct
gccgtggttgcactgaataaagcaattgaagccgtgaaagccacacaccaagctctcttt
aataataaaaaggtcgttgatgtttttttagttggggtagggggtgtcggtggcgagttg
attgagcaaattaaacatcagaaaagttatctagccaagaaagatattgaaattcgggtg
tgtgcgattgccaattcaaacaaaatgttattaaaagcagatggcttaaatttagaaaat
tggcaagcagatttggaaaccgcgactcaaccttctgattttgatgtgttactgtccttt
attaaattgcaccatgtcgtgaatccggtatttgtggattgtacgtcagcggattctgta
gctggtttatatgtgcgtgcactgggagaagggttccatgttgtgacaccaaataaaaaa
gccaatacgcgtgaactggcgtattataatgcactgcgtgaaagtgcccgtaataaccaa
cgtaaattcttgtatgatacaaacgttggcgcagggttacccgtcattgaaaacttgcag
aatttattggctgcgggtgatgaagtcgtcaagtttagtggcgtactctcggggtcgttg
tcctttatctttggcgagttagaaaacggactcacgttatctgaagcgactgctcttgcg
cgtgaaaaagggtttactgaacctgatccaagagatgatctttctggacaagatgttgcc
aggaaactgttgattttagcgcgtgaaaccggtgcacaattggaattaacagatattgag
gtagaaagtgtgctcccagcgggatttgctgaagggaagaccacacaggaatttatggcg
atgttaccacaattagacgcagaatttagccaacgtgttgctaacgcgaaagcagaaggg
aaagtattgcgttatgtgggacaaattgaaaacaacagttgtaaagtctctgtgttggaa
gtcgatgcagatgatccattatataaagtaaaaaatggtgaaaatgcgttagccttctat
actcgttattatcaaccgattccgttacttttacgtggttatggcgcgggaaattccgta
actgcagcggggatttttgccgatatattgagaacgctacaacattaa
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