KEGG   Podarcis muralis (common wall lizard): 114600698
Entry
114600698         CDS       T06059                                 
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
  KO
K04514  Rho-associated protein kinase 1 [EC:2.7.11.39]
Organism
pmua  Podarcis muralis (common wall lizard)
Pathway
pmua04270  Vascular smooth muscle contraction
pmua04350  TGF-beta signaling pathway
pmua04510  Focal adhesion
pmua04520  Adherens junction
pmua04530  Tight junction
pmua04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:pmua00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    114600698 (ROCK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    114600698 (ROCK1)
   04520 Adherens junction
    114600698 (ROCK1)
   04530 Tight junction
    114600698 (ROCK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    114600698 (ROCK1)
 09150 Organismal Systems
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    114600698 (ROCK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pmua01001]
    114600698 (ROCK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:pmua03036]
    114600698 (ROCK1)
Enzymes [BR:pmua01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.39  ROCK-subfamily protein kinase
     114600698 (ROCK1)
Protein kinases [BR:pmua01001]
 Serine/threonine kinases: AGC group
  DMPK family [OT]
   114600698 (ROCK1)
Chromosome and associated proteins [BR:pmua03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    114600698 (ROCK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Rho_Binding PH C1_1 Pkinase_C APH
Other DBs
NCBI-GeneID: 114600698
NCBI-ProteinID: XP_028593061
LinkDB
Position
7:47858440..47916374
AA seq 1376 aa
MSTGESFDSRFEKIGMMIKDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDTFLNKYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLSFP
DDNDISKDAKNLICGFLTDREVRLGRNGVEEIKRHPFFKNDQWSWENLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNHQYLSSCTANSNDNRAST
NVDKSLLESLQKTIYQLEEQLHNEMELKDEMEQKFRTSNIKLDKIMKELDEEGSQRKNLE
STVTQVEKENMLLQHRINEYQRKIEQENEKRRNVENEVSTLKDQLEDLKKISQHSHITNE
KITQLQKQLEEANDLLRTESDTAARLRKSHTEMSKSVSQFEALNRELQERCRILESTKLQ
VEKDYYQLQAALEVERRDRSHGSEIIGELQARVTSLQEEIKGLKNNLERVEEERKQAQDM
LNHSEKEKNNLEIDLNYKLKILQQRLEQEVNEHNINKARLTDKHQSIEEAKSVAMCEIEK
KVKEERSAREKAENRIVQIEKQCSMLDFDLKQSQQKLEHLSEQKERLEDEVKNITLQLEH
EINKRVMAQNDLKIHAIEADNLKSSEKQLKQEINTLLEAKRLAEFELAQLAKQYRGNEGQ
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNKETQKKIQELQNEKETLAAQLDLAETK
AESEQLARALLEEQYFELTQESKKAASRNRQEIADKDNIVSRLEETNNTLTKDVAFLTKE
NSELNEKIKKLEEDYILKKEEEINTIKMQYEKNLNTERTLKTQAVNKLAEIMNRKDFKLD
RKKVNMQDYKKKEKENRKLQLELNQEKEKFNQMVIKYQKELNEIQAQIAEESAHKNELQM
QLDSKESDIEQLRSKINDLQLGMDSTSVASLPPDDTDGNVIESRMEGWLSIPNKGNIKRH
GWKKQYVVVSSRKILFYNDEQDREHSNPSMVLDIEKLFHVRPVTQGDVYRAETEEIPKIF
QILYANEGECRKDLEAEPVQPPEKTTFLNHKGHEFIPTLYHFPANCEACAKPLWHVFKPP
PAVECRRCHVKCHRDHLDKKEELIAPCKVSYDVTSARDMLLLAPCQEDQKKWVSHLVKKI
PKTPPSSFVRASPRTLSTRSSANQSFRKVKNASGKARSKEYGSVGDITHSENSSYC
NT seq 4131 nt   +upstreamnt  +downstreamnt
atgtcgacgggagaaagctttgactctcggtttgagaaaatcggaatgatgataaaggat
cccaaatctgaagtgaactcggactgcttattggatggattagatgcattggtgtacgat
ttggactttcctgccttaagaaaaaataaaaacatagacacctttttaaacaaatataaa
gacacaataaacaaaatcagagatctgcgtatgaaggctgaagattatgaagtggtgaaa
gtgattggcagaggtgcatttggggaagttcagttggtaagacacaagtcatcacgaaag
gtttatgccatgaagcttttgagcaagtttgaaatgataaaaagatcagattctgcattc
ttttgggaagaaagagatatcatggcatttgcgaatagcccttgggttgtgcagttattt
tatgcattccaagatgaccgctacctttacatggtgatggaatacatgcctggtggggac
ctagtgaatttaatgagcaactatgatgttcctgagaaatgggcaagattttatactgca
gaagttgttcttgcattagatgcgattcactcaatgggctttattcacagagatgtaaag
cctgataatatgctgctagataaatctggtcatttaaaactagcagattttggtacctgt
atgaagatgaataaggaaggcatggtacgatgtgatacagctgttggaacaccagactat
atatccccagaagtgttaaaatctcaaggtggtgatggttactatggacgagaatgtgac
tggtggtctgttggtgtctttttgtatgaaatgcttgtgggggatacacctttttacgca
gattctttggttggaacatacagtaaaattatgaaccataagaattctcttagctttcct
gatgataatgatatttcaaaagatgcaaaaaatcttatttgtggcttcttaactgacagg
gaagtcagattaggccgaaatggtgtggaagaaatcaagcgacaccctttcttcaaaaat
gaccagtggtcttgggaaaaccttagagacactgtagcacctgttgtgcctgatttaagt
agtgatattgatactagtaactttgacgatttggaggaagataaaggagaagaagaaaca
tttcctataccaaaagcatttgttggtaaccagctgccttttgtaggatttacttactac
agtaaccatcagtatttatctagctgtacagcaaactctaatgacaacagagcaagcacc
aacgtagataaaagtttgctggaatctctgcagaaaactatctatcaacttgaagaacag
ctacataatgaaatggaactgaaagatgaaatggaacaaaaattcagaacgtcaaacatt
aaattagacaagataatgaaggaattagatgaagagggcagtcagagaaaaaatttggaa
tcaacagttactcaggttgaaaaggaaaatatgcttctgcaacatagaataaatgaatat
caaagaaaaattgagcaggagaatgagaaacgtcgaaatgtggaaaatgaagtgtcaacg
ctaaaagatcagttggaagacttaaaaaaaatcagtcagcattcacatattacaaatgaa
aaaataacgcagttgcaaaagcaacttgaagaggccaatgatttactgaggacagagtca
gataccgcagcaaggttgagaaagagtcacaccgaaatgagcaagtcagtaagtcagttt
gaagccctaaacagagaattgcaagagagatgcagaatcctggaaagcacaaaattacaa
gtggaaaaagactattatcaacttcaagctgcgttggaagtggaaagaagggataggagt
catggatcagaaattattggagagctacaagctcgggttacatctttacaagaagaaatc
aaaggtttaaagaacaatcttgaaagagtggaagaagaaagaaagcaggcccaggacatg
cttaatcattctgaaaaggaaaagaataatttagaaattgatctaaactacaaactcaaa
atattacagcagcgtttagagcaagaagtaaatgagcataatataaataaagctcgttta
actgacaagcaccagtcaatagaagaggccaagtcagttgcaatgtgcgaaattgaaaaa
aaggtgaaagaagagcgatcagcaagagagaaggcagaaaatcgaatagtccagattgaa
aaacaatgttccatgctagactttgacttgaagcaatctcaacagaagctggagcacctt
agtgaacagaaagagagactagaagatgaggttaagaatatcacacttcagctggagcat
gagattaataagagagtgatggcacagaatgacctgaagattcatgctatagaggcagat
aacttaaaaagttctgagaagcagctaaaacaggagatcaacacgttgttggaagcgaag
agattagcagaatttgagttggctcaactggcaaagcagtacagagggaatgaaggccag
atgcgtgaactgcaagatcaactagaagctgaacagtacttttctactctatacaaaact
caggttaaagaacttaaagaagaaattgaggagaagaataaagaaactcagaaaaaaata
caggaattacaaaatgaaaaagaaactcttgctgcgcagctagatctggctgaaacaaaa
gctgaatctgagcagttggcccgagctctccttgaggagcagtattttgaattgactcag
gagagcaagaaagccgcatcacgaaacagacaagaaattgccgacaaggataatattgta
agccggcttgaagaaacaaataatacattaaccaaggatgtggcatttctaacaaaagaa
aattctgaactaaatgagaagattaagaaactggaggaagattatatattgaagaaagaa
gaagaaataaataccataaaaatgcagtatgaaaagaatttgaacactgaaagaaccctt
aaaacacaggctgtcaacaaactggctgaaattatgaatcgcaaagattttaagctagat
agaaagaaagtaaacatgcaagactacaagaaaaaagagaaggaaaatcggaagttacaa
ttggaacttaaccaagaaaaagagaaatttaatcagatggtaataaaataccagaaggag
cttaatgaaattcaagcgcaaattgcggaagagtctgcacataagaacgaacttcagatg
cagttggatagcaaggaaagtgatatagaacaactgcgcagtaaaattaatgacttacaa
ctaggcatggactcaactagtgttgccagccttccgccagatgacactgatgggaatgtt
atagagtcaagaatggagggctggctttcaataccaaacaaaggaaatataaaacgtcat
ggatggaagaagcagtatgttgtggtcagcagcagaaagattttgttctataacgacgaa
caggacagagaacattctaatccatccatggtattagatatagaaaaattgttccatgtg
cgaccagtaacacagggagatgtctatagagcagaaactgaggaaattcctaaaatattt
cagattctatatgccaatgagggcgagtgccgaaaagatttggaagcagaaccagttcag
ccaccagagaagacaacctttctgaatcataaaggtcatgaattcatcccaacattatac
cactttccagccaactgtgaggcttgtgccaagcccctctggcatgtatttaagccacca
cctgcagtagaatgtaggcgatgccatgttaagtgccatagagatcacttggataaaaag
gaagaattaattgcaccatgtaaagtgagttatgatgtaacttcagcaagagatatgttg
ttgttagccccctgtcaagaagatcaaaagaaatgggtttctcatttagtaaagaagatc
cccaagacaccaccatccagttttgttcgtgcttcccccagaactctttccacaaggtcc
tcagcaaatcagtcattcagaaaagttaagaatgcgtctggaaaagctaggtcaaaggag
tatggatctgtgggggacattacccattcagaaaactcaagttactgttaa

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