Protobothrops mucrosquamatus (Taiwan habu): 107292158
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Entry
107292158 CDS
T05763
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
pmur
Protobothrops mucrosquamatus (Taiwan habu)
Pathway
pmur00270
Cysteine and methionine metabolism
pmur00480
Glutathione metabolism
pmur01100
Metabolic pathways
pmur01240
Biosynthesis of cofactors
pmur04216
Ferroptosis
Module
pmur_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
pmur00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
107292158 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
107292158 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
107292158 (GCLC)
Enzymes [BR:
pmur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
107292158 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
107292158
NCBI-ProteinID:
XP_015676706
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All DBs
Position
Unknown
AA seq
583 aa
AA seq
DB search
MLVAFDHKNKRARLSLTGEGVLQTLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKKDVAICTVTSFPRLGCPGFTIPAYHPTPIETGASKSL
FFPDEAINNHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPSDDGEAARAAK
PDHVYMDAMGFGMGNCCLQVTFQACSIFEARYLYDQLATICPIVMALSAAAPFYRGYVTD
IDCRWGIISASVDDRTREERGLEPLKNNRFRINKSRYDSIDSYLSECGEKYNDIDLTIDK
EIYEHLVKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKV
AQKRDAVQQGMFYFRKDISKGGNAVVDGCGATQNGTETDVEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTAAKWMREFVANHPEYKHDSV
ISEEMNYSLMWKCNEIAHEQVECPELLGVGLNKLKYSGIKATS
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgttagtagcttttgaccataaaaataagagagcacggttgtctttaactggagaagga
gtacttcagactttgcaagaaaaaggtgaaagaacaaatccaaaccatccaacattatgg
agaccagaatacggaagctacatgatcgaagggactcctgggcagccctatggaggaaca
atgtctgaatttaacactgtacaggacaacatgagaaagcggcgccaggaagctgcttca
gtactaaaaaaagatgtagctatttgcactgtcacatcatttccaagattaggttgtcca
ggatttacgataccagcatatcatccaacacctattgagacgggagcctcaaagtctctt
ttcttcccagatgaggctataaacaatcatcccaggtttagtactttaacgagaaatatt
cgacatagaagaggcgaaaaagtagttataaatgtaccaatatttaaggacaagaatact
ccatcaccgtttatagaaacatttcctagtgatgatggtgaagcagcaagagcagctaag
cccgatcatgtatatatggatgccatgggatttggcatgggcaattgttgccttcaggta
acattccaagcctgcagcatttttgaagcaagatatctttatgatcagctagccaccatc
tgccccattgtgatggctttaagtgctgcagctcctttttacagaggctatgtgacagat
attgattgccgttggggaattatatctgcatcagtagatgacagaacaagagaggagagg
ggtctagagccattgaagaacaaccgtttcagaatcaataaatccagatacgattccata
gacagttatctctcagaatgcggtgaaaagtacaatgacattgatttgacaatagataaa
gaaatctatgagcatctagtaaaagagggcattgatcatcttttggcacaacacattgcc
cacttatttattcgtgaccctttgacactgtttgaagaaaaaatacatctggatgatgca
aatgaatctgaccattttgagaatattcagtcaacaaattggcagactatgagatttaag
cctcctcctccaaattcagatattggatggagagttgagttcagaccaatggaggtccaa
ttaacagactttgaaaactcagcatacgttgtgtttgttgtactattaactcgagtcatt
ctctcatataaattggattttctcattcctttgtccaaggtggatgaaaacatgaaagta
gctcagaagcgagatgctgtccagcaaggcatgttttattttagaaaagacatttctaaa
ggtggcaatgcagtagtggatggatgtggtgcaactcaaaatggtacagaaacagatgta
gaagaatatacattaatgagcatagatacaatcattaatggaaaggaaggagtatttcca
ggattaattccaattttgaactcttaccttgaaaatatggaagtggacgtggatacaaga
tgcagcattctaaactatctgaaactaataaaaaagagagcatcaggcgaattaatgaca
gctgctaaatggatgcgagaatttgttgcaaaccacccagaatacaagcatgatagtgtg
atctcagaagagatgaattacagcctgatgtggaaatgcaacgaaattgcacacgagcaa
gttgaatgtcctgagctgcttggagtgggcttaaataaactaaaatacagtggaattaaa
gccacttcttaa
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