Pieris napi (green-veined white): 125052646 Help Entry 125052646         CDS       T08706                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism pnap  Pieris napi (green-veined white) Brite KEGG Orthology (KO) [BR:pnap00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pnap04040]     125052646    04990 Domain-containing proteins not elsewhere classified [BR:pnap04990]     125052646 Ion channels [BR:pnap04040]  Voltage-gated cation channels   Ryanodine receptor    125052646 Domain-containing proteins not elsewhere classified [BR:pnap04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    125052646 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 GWT1 Motif Other DBs NCBI-GeneID:  125052646 NCBI-ProteinID:  XP_047509555 EnsemblRapid:  ENSPNPG00015036568 LinkDB All DBs Position 9:complement(9904392..10013572) Genome browser AA seq 5117 aa AA seqDB search MAEAEGGASEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDL SQCVFVIEQALSVRALQELVTAAGSETGKETLGKGTGSGHRTLLYGNAILLRHLNSDMYL ACLSTSSSQDKLAFDVGLQEHSQGEACWWTLHPASKQRSEGEKVRVGDDLILVSVATERY LHTTKENEVSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPST WNKDGGLNIVVYEGGSVMSQARSLWRLELARTKWAGGFINWYHPMRIRHITTGRYLGVND QNELYLVSREEATTASCAFCLRQEKDDQKVVLEDKDLEVIGAPIIKYGDSTVIVQHSETG LWLSYKSYETKKKGLGKVEEKQAILHEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTK FINGLETLQENRRHSMFFASVNLGEMVMCLEDLINYFAQPEEDMEHEEKQNRFRALRNRQ DLFQEEGILNLILEAIDKINVITSQGFLAGFLAGDESGQSWDMISVYLYQLLAAIIKGNH TNCAQFANSNRLNWLFSRLGSQASGEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLL EKHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDYLLPGKNLLLQTALVDHVSSVRPNIFV GRVEGSAVYQKWYFEVTMDHIEKTTHMMPHLRIGWANTTGYVPYPGGGEKWGGNGVGDDL YSFGFDGAYLWSGGRKTQVNKTHAEEPFIRKGDVIGCALDLTVPIINFMFNGVRVTGSFT NFNLEGMFFPVMSCSSKLSCRFLMGGEHGRLRYAAPEGYSPLVESLLPQQILNLEPCFYF GNLAKRALAGPPLVQDDTAFVPTPVDTASITLSSYIEQIRDKLAENIHEMWAMNKIEAGW MYGDQRDDLHKVHPCLVPFERLPAAEKRYDIQLAVQTLKTILALGYYISLDKPPARIRNV RLPNEPFMQSNGYKPAPLDLSAVTLTPKMDELVDQLAENTHNLWARERIQQGWTYGLNED PDMNRSPHLVPYPKVDDAIKKANRDTASETVRTLLVYGYNLDPPTGEQHEALLAEASRQK QAEFRTYRAEKNYAVSSGKWYFEFEILTAGPMRVGWAHADMPPGMMLGQDENSWAFDGYN SLKWHGGSSDTFGQQLKVGDIVACFLDVPDQTISFSLNGELLMDALGGETTFADVQGDNF VPACTLGVGQKARLSYGQDVNSLKYFTTCGLQEGYEPFCVNMNRDVTHWYTKDQPIFENT DEMIDTRIDVTRIPAGSDTPPCLKISHNTFETMEKANWEFLRLSLPVICHAEFIDESEKA RRWVEIKDRQQILMKEAVEAQMPAHIDQIMRSGFTMNDIKGLHYDENQEDVKIKRQPSRP PRKGSITRNVTIQNYNLQPGQNGMNRSTSEAEMSKYELGVQSLPEDTKKDKRGRSPFKFF RSKRGESGDRGKSRKSKTPDPYTDTEVSPDRARRPNPQIRVSQANQRYNIQNRNNGANMY DSQGALNTNLTVPTPTQDRKQMTTATLDKSATETIGNEIFDADCLKLINEYFYGVRIFPG QDPTHVYIGWVTTQYHLHSKDFNQNKVTKSSVIITDDYDRVIESVNRQSCYMVRADELYN EVMAEATAKGASQGMFIGCSVDTSTGTVSFTCEGKDTSIKFKMEPETKLFPAIFVEATSK EILQIELGRSSTSLPLSAAVLPTSDKHVNPQFPPRLKVQCLKPHQWARVPNQFLQVHALK LSDIRGWSMLCEDAVSMLALHIPEEDRCIDILELIEMDKLLSFHAHTLTLYAALCYQSNY RAAHALCQHVDQKQLLYAIRSQYMSGPLRQGFYDLLIALHLESHATTMEACKNEFVIPLG PELKSLYEDREMCHSLRSLQTESVRPHMNMTNIAENISDISNLYSPYFPLEVVREFVMQA LAEAVETNQVHNRDPTGGSNENLFLPLIKLVDRLLLVGMMRDEDVEKLLIMINPETWDPT FDKEGKDEHRKGLLHMKMAEGAKLQMCYLLQHLNDIQLRHRVESIIAFAHDFVGELQTDQ LRRYTEIKQSDLPSAVAAKKTREFRCPPREQMNAILSFKHLEDEDPENCPCGEELIARMN EFHDALMSHVSLSALQEPDGDQSNEPEVKPGAFGKLYNIINTVKELEDEAKALEEEKKKT PEEKFRKVLIQTIVNWAEESQIETPKLVREMFSLLVRQYDAVGELIRALEKTYVINAKTK LDVAEMWVGLSQIRALLPVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRVLRVHENVMA VMMNTLGRRAQAQSDAPATSPPTPEDKEKDTSHEMVVACCRFLCYFCRTGRQNQKAMFDH FDFLLENSNILLARPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSN SELIEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRG EGEGLLKAIVDANKMSERIADRRKLRDLEQEGDISFSHPLPESDDDEDYIDTGAAILNFY CTLVDLLGRCAPDAGVIALGKNESLRARAILRSLVPLEDLQGVLSLRFTLNNPAAGEERP KSDMPSGLIPGHKQSVGLFLERVYGIETQELFYRLLEEAFLPDLRAATMLDRNDGCESDM ALSMNRYIGNSILPLLIKHANFYNEAENYASLLDATLHTVYRLSKNRMLTKGQREAVSDF LVALTSAMQPSMLLKLLRKLTVDVSRLSEYTTVALRLLTLHYERCAKYYGSTSGQGSYGS SSDEEKRLTMMLFSNIFDSLSKMDYEPELFGKALPCLIAIGCALPPDYSLSKNYDDEFYG KESQAAGADNPQYDPQPINTSSVALNNDLNTIVQKFSEHYHDAWASRKIENGWVYGENWS DSQKTHPRLKPYNMLNDYEKERYKEPVRESLKALLAIGWSVEHSEVDIPSNNRSSMRRQS KSGIDSATPFNYNPHPVDMTNLTLSREMQNMAERLADNAHDIWAKKKKEELVTNGGGIHP QLVPYDLLTDKEKKKDRERSQEFLKYLQYQGYKLHRPSKASQIDTEQTTTGVAIELRFAY SLLEKLIQYIDRATINMKLLKPSTTFSRRSSFKTSTRDIKFFSKVVLPLMEKYFSTHRNY FIAVATATNNVGAASLKEKEMVAALFCKLASLLRSRLAAFGPDVRITVRCLQVLVKGIDA KSLVKNCPEFIRTSMLTFFNNLADDLGHTIFNLQEGKYAHLRGTHLKTSTSLGYINGVTL PILTAMFDHLANCEYGADLLLDEIQVASYKMLGSLYTLGTDVTLTHDRKYLKTEIERHKP ALGSCLGAFSSTFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDIMAKMEQSMPTLETILN EVDHFVESDKTYNEAPHIIDVVLPLLCSYLPFWWAQGPDNVTPTGGNHVTMVTAEHMNQL LKNVLKLIKKNIGNESAPWMTRIATYTQQIIINSSEELLRESFLPLAERVRKRTDNMFHK EESLRGFIKSSTDDTSQVESQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLRNNVPEAE ELYNHVAEIFNIWSKSQYFLKEEQNFISANEIDNMVLIMPTATRRVTTVVDGTQQGGGKK KKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRFLKKMSEQDVA EFAKTQLTLPDKIDPADEMSWQHYLYSKLGSKSKTAITVETSENKAKIIDDTVERIVAMS KVLFGLHMIDHPQQMSKNVYRSVVSIQRKRAVIACFRQTSLHSLPRHRACNIFARTYYEL WLEEENIGQEVMIEDLTQTFEDAELKKSDVVEEEGKPDPLTQLVTTFCRGAMTERSGALQ EDPLYMSYAHIIAKSCGEEEEEGGEEEEGGGEPEGEDEGKSSIHEQEMEKQKLLFHQARL ANRGVAEMVLLHISASKGVPSDMVMKTLQLGISILRGGNIDIQMGMLNHLKDKKDVGFFT SIAGLMNSCSVLDLDAFERNTKAEGLGVGLEGAAGEKNMHDAEFTCALFRFIQLTCEGHN LEWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDPAGKANFFKAIG VASQVFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKEL LNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSSAS FKEIDANNDGWVLPKDFKEKMEQQKSYSPEEIEFLLACCETNHDGKLDYIGFCDRFHEPA KEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEIMGGSKRIERVYFE IKESNIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMAASE ESASGPKNREAAYTYLGDDDDERAGKDPFRRGYQSVKDAIAATFSFLSPSNIKAKIADMQ QMPPAELVVGFLKLFFYLFYYIGYGFVVVIRYIFGVLLGLMRGPHVEEPPPPEPTEEEKI GQFKHRLITQSPSRHLPALPAADDTGQMQVSAFGLDITKEDNGQIQVKPHESPTTSTPSS GEEAEVSLDESIEHTEEQQPPSLIDLLGGEQAKKQAQERVEAQAAQQAAMSAIEAESKKA VQVPAPSALSQVDLSQYTKRAVSFLARNFYNLKYVALVLAFCINFVLLFYKVSIPDSDKE GSGIGDIISGSGSGQGSGSGEGSGESEDDDSLEVVRIDEDFFYMEHVIKMAAALHSIVSL AILIGYYHLKVPLAIFKREKDIARRLEFDGLYIAEQPEDDDLKSHWDKLVISAKSFPVNY WDKFIKKKVRAKYSETYDFDSISNMLGMEKTSFSAQEDEGNKGLWNYIVNIDWRYQVWKA GVTITDNSFLYSLWYFSFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLT VMLLTIIVYIYTVIAFNFFRKFYVQEEDDEINRNCHDMLSCFVFNLYKGVRAGGGIGDEL EPPDGDDSEVYRIIFDISFFFFVIIILLAILQGLIIDAFGELRDQLESVKEDMESNCFIC GINKDYFDKVPHGFDTHVQREHNLANYMFFLMHLINKPDTEYTGQETFVWNMYTQRCWDF FPVGDCFRKQYEDVMGE NT seq 15354 nt NT seq  +upstreamnt  +downstreamnt atggcggaagcggaaggaggagcaagcgagcaggatgatgtttcattcctgcgaacggag gacatggtctgtctctcgtgcacggctacgggagaaagggtgtgcctggctgcagagggg ttcggaaaccggcactgcttcttggagaacatcgctgataaaaatatcccaccggatcta tcacagtgcgtctttgttattgaacaggccttgtcagtacgagctctccaggaattagtc acagcggctggctcagagaccggcaaagaaaccttaggtaaaggcacaggttccggtcac agaacattgctttacggcaatgctatcttgctacgtcatctgaacagtgacatgtacttg gcgtgtctatccacgtcatcatcacaagacaagttggcgtttgatgtcggtttacaagag cattctcaaggtgaagcatgctggtggacactgcatcctgccagcaaacaaaggtctgag ggtgagaaggtgcgagtcggtgatgatctgatcttagtgtcggttgctactgagagatat ttgcatacaaccaaagagaacgaagtttcaatagtaaacgcctcattccacgtcacacac tggtcagtacagccttatggcactggaatttcccgtatgaagtacgtgggttatgtcttt ggaggtgacgtgctaaggttcttccatggcggtgatgaatgcctcacgatacccagtaca tggaacaaagatggggggctaaatatcgtggtatatgaaggtggttcagtaatgtctcaa gctcgctctttatggcgattggagttggcgcgtactaaatgggctggtggttttataaat tggtaccaccccatgaggataagacacattaccacgggccgctatttgggagtcaacgat cagaacgagctgtatttggttagcagagaggaagctacaacagcatcatgtgctttctgc ctccgacaagagaaggatgaccagaaagtggttttggaagacaaagacttagaggtcatc ggggctcccatcatcaagtatggagactccactgtcattgtacagcattctgaaaccgga ttgtggttatcttataagtcttacgaaacgaagaaaaagggcttaggtaaagtagaagag aaacaagcgatactccacgaggaaggcaagatggatgatggtttggacttctctcggtcc caagaagaggagtctagaaccgccagggtgattaggaagtgttcttcactcttcacgaag ttcattaatggccttgagacattacaagagaacagacgtcactctatgttcttcgcgtct gtgaatcttggagaaatggttatgtgtcttgaggatttgattaattacttcgcacaacct gaagaggatatggaacacgaagaaaaacaaaatagattccgagccctccgaaaccgccaa gatctattccaagaggaaggaatattaaaccttattttagaagccatagacaagataaac gtgattacgtcacagggcttccttgccggctttttggcgggagacgaatcgggacagagt tgggatatgatatctgtgtatttgtatcaacttttagctgcgataatcaaaggcaaccac acaaactgtgcccaattcgcaaactcgaaccgcttgaactggttattctcccgtctgggc tcgcaggcatctggagagggaactgggatgctggatgtactgcattgtgtgcttattgac tcgcctgaagcgttgaatatgatgcgagatgagcacatcaaagtaatcatctcgctttta gagaaacacggccgcgatccgaaagtattggacgtgttgtgttcgctttgtgtgggtaat ggagtagctgtcaggtcgtcgcagaataacatttgtgactatttactaccagggaagaac ttgctactccagactgctttagtggatcatgtgtcaagtgtgcgaccaaatatttttgtg ggtcgtgtagaaggttctgccgtataccaaaaatggtatttcgaagtcaccatggaccat attgagaagaccacacacatgatgccgcatttgaggattggatgggcaaatacaacgggt tacgtaccttaccccggcggcggtgaaaagtggggtggtaatggggtcggtgacgatctt tattcctttgggtttgatggggcttacctgtggtctggtgggcggaagactcaagtcaac aagactcatgctgaggagccctttatcaggaaaggtgacgtcattggctgtgctttggac ctcacagtcccgatcatcaacttcatgttcaacggagtgagagtcacgggttccttcacg aatttcaacctggaaggaatgttcttccctgtcatgagttgttctagcaagttgagttgc cgttttctcatgggaggggaacacggtaggctaagatacgcggcccccgaaggatactcc ccattggtagaatctctcttaccgcagcagatattgaacctggagccatgcttctacttt ggcaacttggctaaacgcgctctggctggtccgcccttggtacaggatgacactgctttt gtgcctacacctgttgatactgcctctattacactgtcgtcatatatcgaacaaattcgg gacaaacttgcggaaaatatacacgaaatgtgggccatgaataagattgaagcaggttgg atgtacggagaccaaagagatgatttgcataaagtacatccttgtctggtccccttcgag cgtcttccggctgctgaaaagcgatacgatatccagttagcagttcaaactcttaagact atattggccctgggttactatataagtttggataaaccaccggctcgtatccgtaacgtc agattgcccaacgaaccatttatgcagtcgaacggctacaagccagctccattggaccta agcgcagtgacccttactcctaagatggacgaattagtggaccaattagcagagaacact cacaatttatgggcgagggagcggatacaacaagggtggacttatggccttaatgaggat cccgatatgaatcgttcaccccatttagtgccgtatccaaaagttgacgacgcaattaaa aaagctaacagagataccgcgtctgagaccgtaaggactctactagtttatggatacaac ttggatccaccaacgggagaacaacacgaagcattacttgctgaagcctcaagacaaaag caagcagaatttagaacatacagagccgagaagaattacgctgttagttctggaaaatgg tactttgaattcgaaatacttactgctggaccaatgagggttggttgggcccatgctgat atgcctccaggtatgatgttggggcaagacgaaaattcctgggcattcgacggatataat tcgttaaaatggcacggcggttcaagcgacacgtttggacagcagctcaaagtaggcgat attgtcgcctgtttcttagatgtaccagatcaaacaattagtttttcgctaaatggtgaa ttgttgatggacgcgcttggtggtgagacaacatttgcagatgtccaaggtgataacttc gtgccagcctgtacccttggagtcggtcaaaaagctaggttatcatatggtcaagatgtg aactctctaaagtacttcacaacctgtggtctccaagagggttacgaacctttctgtgtc aacatgaaccgtgatgtaacacattggtatacaaaagatcagccgatatttgagaacaca gatgaaatgatcgacacgaggatcgatgttaccaggattccagctggctctgacacgccg ccatgcttaaaaatatcgcacaacacatttgagacgatggaaaaggcgaattgggagttc ctcaggctgtcgctacctgttatatgccatgctgagtttattgatgaatcggaaaaagct cgccgttgggtggagatcaaggatcgtcagcagattctgatgaaggaagcggttgaagct caaatgccggcgcatatcgaccaaataatgagaagtggcttcaccatgaacgatattaaa ggtctccactacgatgagaatcaagaagacgtaaaaatcaagaggcagccctcacgtcca ccccgcaaagggtctatcacacgcaacgtcacaatacagaattacaatttacaaccaggt caaaacggaatgaaccggtcgacaagtgaagcggaaatgtcaaaatatgaactcggggta cagagtctgcctgaagataccaagaaagataagagaggaaggtcgccattcaagttcttt agaagtaaaagaggagagagtggggatagaggtaaatcgaggaagtcgaaaacccctgat ccctacacagatactgaagtgtccccagatagggctcggcgacccaatccacaaatcaga gtatcacaggccaatcagaggtataacattcaaaatagaaataatggggccaatatgtac gacagtcaaggcgctttaaacacaaacttgacagtgccaacaccaacacaagatcgtaag caaatgacaaccgctacactcgacaagtctgcgacagaaacgatcgggaatgaaatattc gatgctgactgtttgaaacttatcaatgaatacttttacggtgtcagaattttccccggt caggatcccactcacgtgtatataggatgggtgaccactcaatatcatttgcactccaag gactttaatcagaataaagtcaccaagtcttcagttatcatcacagacgattatgatagg gtgattgagagtgtaaaccgccagtcgtgttatatggtgcgagctgatgaattgtacaat gaagtgatggcggaagcaacagcaaaaggagcttcccagggaatgttcattggttgttct gttgatacgtcgactggtactgtatccttcacgtgtgagggaaaagataccagcattaag tttaagatggaaccagaaacaaaactcttcccggcgatattcgttgaggccacatcaaag gaaatcctgcaaatagagctgggtcggtcctctactagtcttccacttagtgctgcagtg ctgccaactagcgacaaacacgtgaacccacaattcccaccgaggcttaaagtgcagtgc ttgaaaccgcatcaatgggctagagtaccgaaccaattccttcaagttcacgctctgaag ttgtctgacattcgtggttggtccatgctctgtgaagacgctgtatccatgttggcttta catattccagaggaggaccgttgcatagacatcttagagttgatagagatggacaaactt ctaagcttccacgcccacactctcacattatatgccgctctctgttaccaaagcaattac agggccgcacacgctttgtgtcaacacgtcgatcagaaacaactgctttacgcgatccga tctcagtacatgtcgggacctctacggcaaggtttctacgatttgctcatcgccttacat ttggagtctcatgccactactatggaagcgtgtaagaacgaatttgtgatacctttggga ccagaactgaagtcgttgtacgaggatcgggagatgtgtcacagccttcgatctttgcag actgagagtgttcggccccatatgaacatgactaatattgcagaaaacatatcggacata agcaacctctactccccctacttccccctcgaagtggtccgggaattcgtcatgcaggct ttggctgaagccgtggagaccaaccaagtacacaacagagatcctactggcggaagcaat gagaatcttttcttgcccttaataaagctggtggatcgcttacttttagtgggaatgatg agagatgaagatgttgagaaacttctcataatgatcaaccctgagacttgggatccgacg tttgataaagagggcaaagatgagcatagaaagggccttctccacatgaaaatggcggaa ggtgcgaaactccaaatgtgctacttacttcaacacctcaacgacattcagttaagacac agagttgagtcaattattgcgtttgcgcatgattttgttggagaacttcaaactgatcag ttgagacgttacacagaaatcaaacagtcagatctgcccagtgcggttgctgctaagaag acgagagaattccgttgtccgccgagagaacagatgaatgctattctaagttttaagcac ttagaagatgaagatccggaaaactgtccatgtggtgaagagctcatcgcgagaatgaat gagttccacgatgctctcatgtcacacgtgtctttgagtgctttgcaagaaccggatggt gatcaatcgaatgagccggaagtaaaaccaggtgcatttggtaaactttacaacatcatc aacactgtgaaggagttagaagacgaagccaaggccctcgaagaagaaaagaagaagact ccagaagagaagttccgtaaagttttgattcagacaatcgtcaactgggctgaggagtcg caaatcgaaacgcccaaactggttagggaaatgttcagtcttctggtccgtcaatacgat gcggtgggagaactaatccgagcgcttgagaaaacatatgtaatcaatgcgaaaaccaaa ctagacgtagctgaaatgtgggtcggactgagtcagatcagagccttattgcccgttcaa atgagtcaggaggaagaggaacttatgagaaagagattgtggaaactcgtcaacaatcac actttcttccaacatccggatctaatcagagtgttacgtgtacacgagaacgtgatggcc gtaatgatgaacacgctaggccgacgtgcgcaggcgcaatctgacgcccctgcaacttca ccgccaactcctgaggacaaggaaaaggacacttctcacgaaatggtggtcgcatgctgt cgtttcctctgctacttctgtcgcacgggcagacagaaccagaaagccatgttcgaccat ttcgacttccttctcgagaactccaacattctgctcgctaggccatctttaagaggatcc actccgctagatgtcgcgtattcgagtctcatggaaaatactgagctggcccttgctttg agagaacactatttggagaagatagcggtgtacttgtctcgttgtggtcttcaaagtaac tctgaactgatagagaaaggttacccagacttgggttgggatccagtggagggagaacgt tatctggatttcctaagattctgtgtttgggtcaacggtgaaagcgtagaagaaaatgca aatcttgttattcgtcttctcatcagaagaccggaatgtctgggtccagcgttgagaggt gaaggcgaaggtcttttaaaggctatagtagacgctaataagatgagtgaaaggatcgca gatagaaggaaattaagggatttagagcaagagggagatatcagtttcagccacccgtta cccgagtcagacgacgatgaagattacatagacacaggcgccgccattttgaacttctac tgtactctcgtggacttgttgggacgctgtgcacccgatgcaggtgttatcgcactgggt aaaaacgaatccctacgtgcccgagccatcttaagatccctggtcccattggaggacctc caaggcgtactcagtttgagattcactctcaacaacccggctgctggcgaagagagacct aaatctgacatgccatccggtttaataccaggacataagcagagtgtaggacttttcctg gaacgagtatatggaattgaaacgcaggagctattctatcgacttctggaagaggccttc cttcctgatcttagagctgctactatgttagacaggaacgacggttgcgagtcagacatg gctttatcaatgaacagatacatcggcaactccatactcccgttgcttatcaaacatgct aacttctacaacgaggctgaaaactacgctagtttgcttgatgctacacttcatactgtg tatagattatcaaagaaccgtatgctgacaaagggtcagcgtgaggccgtgtcagacttt ttagttgctctgacatccgccatgcagccttccatgttactcaagcttttgaggaaactt acagttgacgtctcccgattgtctgaatatactactgtggctttaaggcttttaacatta cactacgagcgatgtgcaaagtactatggcagtaccagcggtcaaggctcctacggatcc tcgtctgatgaagaaaagagactcacaatgatgctcttctcgaacatcttcgactctctc agcaagatggactacgagccagagttgtttggaaaagctctgccttgcttgattgctatt ggttgcgctctccctcctgactattcgctctcaaagaactatgatgacgagttctatggc aaggaatctcaggctgcaggcgcagacaatccgcagtacgaccctcagcccatcaatacc tcatcggtggctctcaataacgaccttaacacaatcgttcagaagttctccgaacattac cacgatgcttgggcgtcaagaaaaatcgaaaatggttgggtctacggtgaaaactggtct gatagccaaaagacgcacccacgcttgaaaccctacaacatgctgaatgattacgagaaa gaacgttacaaggagcccgttcgtgaatccctcaaggctcttcttgctattggctggtcg gtagaacattcggaagtggatatacccagcaacaataggagttccatgagacgacagtct aagagtggcattgactcagcaacgcccttcaactacaacccacatccagtggatatgacc aatctgactctgtcaagagagatgcagaacatggctgagaggttagctgataacgcgcac gacatctgggcgaagaagaagaaagaagaacttgttaccaatggaggtggtattcatccg caacttgttccttacgatctcttaaccgacaaggagaagaaaaaagaccgcgaaaggtct caagaattcctcaaataccttcaataccagggttacaaactacacagacccagcaaggcg tcccaaattgacacggaacagaccactacgggtgtcgcaatagagctcagattcgcgtat tccttgttggagaaactgatccagtacatcgaccgcgcgacgattaatatgaagctccta aaaccgtctactactttcagtagacgatccagctttaagacaagcacgagggatattaag ttcttctctaaggttgtactacctttgatggagaagtacttctcaacacatcgtaactac ttcatagcagttgccacagcgactaacaatgttggtgcagcgagtttgaaagagaaggaa atggtggctgctttgttctgtaaattggccagtctattacgatctaggttagcagcgttc ggcccggatgtacgtataaccgtccgttgtctacaagtccttgtgaagggcattgatgct aaatccttggtgaagaactgtccggaattcatcaggacctccatgttgacattcttcaat aatctcgctgacgatttggggcatactatattcaacttacaagagggtaaatatgcacat ctccgaggtacccacctcaagacatcgacatctttgggctacatcaatggagtgacgcta ccaatattgacagcgatgttcgatcatctagctaactgcgaatatggagcggatttgttg cttgacgagattcaagtagcgtcttataaaatgttgggctcgctatacacgttgggaacg gatgtaacactgacacacgacagaaaataccttaagacggaaatcgagagacacaaacct gcattgggttcatgcctcggcgcatttagttcaacattcccggtggccttcctggagccg catctcaacaagcacaaccaattctcgttactcaaccgtattgctgatcattcattggaa gctcaagacataatggcgaaaatggaacaatcaatgccaactctagaaacaattctgaac gaagtcgatcacttcgtggaatcagacaagacgtataatgaagcacctcatatcattgat gtggtactgcctttgctgtgctcgtatttgcctttctggtgggcgcagggaccagataat gtaactccgacgggcggcaaccacgtcaccatggtaaccgcagagcacatgaaccagctc ctgaagaacgtcctaaagctgattaagaagaatattggcaatgaaagcgcaccctggatg acccgtattgcaacgtatacgcaacagattataataaactcatctgaggaattgttgaga gagtcgttccttccattggcagaacgtgtgcggaagaggacggataatatgttccataaa gaggagagcttgcgaggttttattaaatcatcaacagacgacacatcgcaagtagagtcg cagatacaagaagactggcagctattagtaagggacatctactccttctacccccttctc atcaaatacgtggatttgcaaaggaatcactggctcaggaataatgtaccagaggccgaa gaactctacaaccatgttgcagaaatattcaacatttggtccaagagccagtacttcctc aaggaggagcaaaacttcatatcagctaacgaaatcgacaacatggtgttgataatgcct actgcgactagaagagtgaccaccgttgtggatggaactcaacagggtggtggaaagaaa aagaaaaagcatcgcgataagaagagagacaaagacaaggaagttcaagcctctttaatg gtggcctgtctgaagagacttctaccggttggtctgaacctctttgcgggtagagaacaa gagttggtgcagcattgcaaggacaggtttttgaagaaaatgtcagaacaagatgtggca gaattcgcgaagacgcagctaacattgccggacaaaattgacccggcggatgaaatgtcc tggcaacattatttgtacagcaagctcgggtccaagagtaagacagcgatcaccgtagaa acttcagaaaataaagccaagataatagatgacaccgtggagaggattgtggctatgagt aaagtgttgtttggcctgcatatgatcgaccatccccaacaaatgagtaagaacgtttat cgttctgttgtctccatacaacgtaaacgcgcagtcatcgcctgtttccggcaaacttca cttcattccttgccaaggcacagggcatgtaatatcttcgctagaacttattatgaactt tggttagaagaagagaatatcggacaagaagtcatgatcgaagatttaacgcaaacgttt gaagatgctgaattaaagaagagtgatgttgtggaagaagaggggaaaccggatcccctt actcaactcgttacaactttctgtcgcggggctatgactgagcgctccggggctttacag gaggatcccctatatatgtcttacgcgcacattatcgcaaagtcctgtggagaggaagaa gaagaagggggagaagaggaggaggggggaggggaacccgaaggagaagacgagggaaag tccagtattcatgaacaagaaatggaaaagcagaagttgttattccatcaagcgcgttta gcaaaccgaggagtagccgaaatggtcctactacacatatccgcttcaaagggcgttccc agtgacatggtgatgaagacgttgcaattgggaatatcaattttgagagggggcaacatt gacatacagatgggtatgctgaatcacctcaaagataagaaggatgtgggcttcttcaca tcaatagctggactcatgaattcctgttctgttcttgacttggatgccttcgaacggaac actaaagctgaagggctgggtgtaggcttagagggcgcggcgggtgagaaaaatatgcac gatgcagaatttacatgcgccctctttaggttcatacaacttacctgtgaaggacacaac ttggagtggcagaactaccttcgaactcaggctggtaacactactactgtgaacgtggtt atatgcacagtagattatctactaaggctgcaggagtctatcatggacttctactggcat tactctagcaaggaactaatagacccagcaggaaaggcgaatttcttcaaagctattggc gtggcttcacaagtctttaacaccctcactgaagtcattcaaggaccttgtacgcaaaat cagcaagcgttagctcattccaggttatgggacgcagtcggtggttttcttttccttttc tctcatatgcaagataagttgtccaagcattcttcccaagtagacctgctgaaagaactg ctaaatcttcagaaagacatgatcaccatgatgctgtctatgctggaggggaacgttgtt aatggaacaattggtaaacagatggtggacactctagtagagtcggcatctaacgtggaa ctgattctaaaatactttgatatgttcctgaagctgaaagatctgacatcaagcgctagt ttcaaagagattgacgctaataatgatggctgggttctgccaaaggactttaaggagaag atggaacagcagaagagttatagtccggaagagatagagttccttctggcttgttgcgag acaaaccacgacggtaaactcgactatatcggcttctgcgatcgattccacgagcctgcc aaagaaattggattcaacttggccgtacttcttactaacctatcagaacacatgccaaat gaacccaggcttgctcgtttcctggaaacggccggatcagttctgaattacttcgagcct ttccttggaagaattgagataatgggtggttctaaacgcatagagcgggtttacttcgaa atcaaggaatccaacattgaacagtgggagaaaccgcagattaaggaatcgaagcgtgcg ttcttctacagcatagtgacagaaggcggtgacaaggagaagttggaggcgttcgtcaat ttctgtgaagatgccatctttgagatgactcatgcttcgggattgatggctgcttcagag gaatccgcaagtggaccaaagaatcgagaggctgcgtatacttacttgggagatgatgat gatgaacgagccggcaaagacccattccgtcgtggctaccaatcagttaaagatgcgata gctgcaacattttcgttcttatcgccctccaacataaaggccaaaatcgcggacatgcaa caaatgccacctgcggaactcgtggttggcttcctgaaactcttcttctatctgttctac tatattggatatggatttgttgttgttataaggtatatattcggcgtattactcggcttg atgcgtggacctcatgtagaggaacctccccctccagagcctactgaggaggagaaaatc ggtcagtttaaacacagattgatcacacaaagtccgtctcgccacctacccgcattgcct gcggcagatgatacaggacaaatgcaagtttctgctttcggtctagatattactaaagag gataatggccagatacaagttaagccacacgagtcaccgaccacttcgacgccatcttca ggtgaggaggcagaagtgtccctagacgagagtattgaacatactgaggaacaacaaccg ccttcactcatcgatttgctcggtggggaacaagcaaagaaacaggcccaagaacgtgtt gaagctcaggcagcgcaacaagctgctatgtccgccattgaagctgaaagcaaaaaggca gtacaagttcccgctccgtcggccctgtcccaagtagacctctcccagtacacgaagcgt gccgtatccttcctcgcgagaaacttctacaacctgaagtacgtcgctctggtgctcgcc ttctgcatcaactttgtgttgctcttctataaggtgtcgatcccggatagtgataaagaa ggttctggtatcggagacatcatcagtggatctggatcaggccaaggttcgggaagtgga gagggcagcggtgaaagtgaggacgatgatagcctagaagtggtgcggatagacgaagac ttcttctatatggaacacgttatcaagatggctgctgctcttcactctatcgtatcgctt gctattctcattggatattatcatctgaaggtgcctcttgccatattcaaacgtgaaaag gacatcgctcgtcgcctggagtttgacggtctctacatcgctgaacaaccggaagatgac gacctcaagagccattgggacaaacttgttatttctgccaaatcattcccggtgaactat tgggacaagtttataaagaagaaagtccgggccaagtattctgagacctacgactttgac tccatatccaacatgttgggaatggaaaagacttctttctcggcccaagaagatgaaggc aataaaggactatggaactacatcgttaacatcgactggcgctaccaagtgtggaaggcg ggtgtcactatcacagacaactcgttcctctactccctctggtacttcagtttctccgtg atgggcaatttcaacaacttcttctttgccgcccatttgctggatgtcgccgtcggtttc aagacgctaagaaccattctacagtccgtcacgcataatggaaaacagttggtgttaact gtgatgctgttaacaatcatagtatacatctacacggtgatagcgttcaacttcttccgc aaattctacgttcaagaagaggatgacgaaatcaacaggaattgccatgacatgctttct tgcttcgtgttcaacctatacaaaggcgtacgtgcaggaggaggtatcggggacgagctc gaacctcctgatggagacgattcggaggtgtaccgcatcatcttcgacatatctttcttc ttcttcgtcatcattatcctgctggctatccttcagggtttgatcattgatgcgttcgga gagctccgtgaccaactggagtcagtcaaagaagacatggagtccaactgcttcatttgt ggcatcaataaggactactttgataaggtgccgcacggtttcgacacacacgtgcaacgg gagcacaatctcgcaaattacatgttcttcttgatgcatctcatcaacaaacccgacact gaatatacaggtcaagaaacattcgtatggaacatgtacacgcaaagatgctgggacttc ttcccagtgggagattgcttccggaaacagtatgaagacgtcatgggagaatag

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