Pieris napi (green-veined white): 125063439 Help Entry 125063439         CDS       T08706                                  Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism pnap  Pieris napi (green-veined white) Brite KEGG Orthology (KO) [BR:pnap00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:pnap04121]     125063439 Enzymes [BR:pnap01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      125063439 Ubiquitin system [BR:pnap04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     125063439 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N zf-UBR Motif Other DBs NCBI-GeneID:  125063439 NCBI-ProteinID:  XP_047525824 EnsemblRapid:  ENSPNPG00015030670 LinkDB All DBs Position 3:complement(13497254..13534714) Genome browser AA seq 5211 aa AA seqDB search MITQFLTVFSKMAAAGGSIEWSTNVKPILTALYGPFFDKNDAVEIIQAIIKSENEFQKHE EAYDLFYTCFACLSAHFISINANNIPPDQLSTAQDAFRIILQQILKKLSEAGQSQDDTSN TLSPNVSVKQLLLPIVALCGIDSNGYLPSDLVILLALLKTAKLPPHGNANENQTTKTSIS SPITSLTSNTSTSEKQPPTNAQRRSDALLERLTMPLRSQVSNVLPPVPSAIGVTSPSSKD SIESAKDGNAQLSSIDIKKWVASTCASLLMELRAGSTILAICSSLPCLQRYLNRWQTAKE SDSAPTFHSDAALLYFLVNEVEVCRLALSLPCLEPFSPERIVTLSDVSAAWLLCATAQAT LHQKDEESEAQTATIVETALNLYSTVGDIFKQSTRAGGYVYQNHTMIGAWVLVCGLHHAL GGAPGPVPPGKSPAKAGPLRPYNLTKMQQSLGVVWVALGGRCLSWLGALLADARLEALSS GSDGAANTPASLHISTHHSAHQRELRLALAAPLHQLLVTLGVVCYRKATNLKRAVVPKDR DAEAEGAAFFRDMRLCSEDSETDDEDSEPLFGLWFESTLVAPDAEDDGLTRLGAAEVADA APDATERGIVPDKAEPYSYILLATDVFTLLTDEIIGGGFERLGGYALRLHEAHHALLAAL ARDLDRESARTDTGTISPCFGARLGALYSAFSSALVRYLHTLSGSPAFAASRPSLQQQLA SAERPNTVPLQVGPRVVKLLGGMVLSKPASERENSILVMWHNLVNTLQEYALQPPSQDHD YEDLNVEHAQLMVYLFHSLTLMQKKSVLLSTANAIIKVVETLGVNDRQRATDLAPHRLTL ATRLMLLLEYLMKHLYDAPQTLLQQIEWNLVVATGLARPSAETSLGEVGTGSDAGQKTRI YCEVPFVEQTYRRLSQDETSMRPKFYALTDTKVNNQENPKFDGLACNFVLGTPHKLKYPV LVDALLALLNCACVCDSRSNRTAVAARAAAHYCFQTAWRLVTSMPPATPHMDKLQAGTAA DLPSPLPLYALVWAPRADAKKAFNPWLKDALVKQGMYTQYAENLLAGVSSSCDNIKYSAW LASETIEHLKRNLRDGLPALLDVISCDAALMRLRVCLVDASSAAEAHPFVPHLLRLLETV LACCRSSASLEAGAAAGPATEVALSVCGVGSGAGAASPPRLGPALKALLPSDVAALLDSR SADPASTVAPSEGAVLELVSAHCELMSDRAAYGVGPSLAMLARSAARLLEIGAAEIADSL ELTRKTLALIVPALTDGRLEFLAEPLTATLHSIVPQAVKAEEIVHEHILRTTYPALCAYA PSAEGTLVHIVRYWEEILDRPAGRAAYEAVFVEGDGEFVLGRILLSAPDTSNPFTDRVVK LFIKIFAGCESEDVSRSLCVGVCKFIGVADRRSLLDLLGHICIYAPTLATVGTADGSPAG TELPTPTGSAPDGHPASLALRNAIRCVLFRTDGDAAPRPDLPVFENPVAATPAPGAQSET NAQQSGNSETCSWSDCSKDSAGAPGTGAGATRAEASSPVGEGTHAALLTALCKHVVLHCE EEASERMLGTLIEVSGEGCPPPLLREMCRLADSHSGTLHELLFPAALAWLSSRVESLCSP EVLEKLEEGTIDNEKTSPQIESACTLLSYLGDALHAIGAPPSHAWRSVSPTWESPSDLGF DLDYADEQQDDDDTSADDSDEDAVLTNKLCTFTVTQREFMNQHWYHCHTCKMVDGVGVCT VCARVCHRGHDISYAKFGNFFCDCGAKPDFSCQALVKREKSSGGGRPAEEAPPAPSLRRR PSSPTPAALLAPPRRPVLAHNIQGCRSFLASYGKWEWCLERVRTLLCALAGPVRAACERT AAVGAHGRAQRALAQLHLGEKKFSHTDSLMLPTLGSQEGAFENVRMSYTGENGQTIRQLI SAHKLRRVAMCCLASPQGRRQHLAVSHEKGKITVLQLSALLKQADSSKHRLTLTRLSSAP IPFTVLSLSGNAANEDLLAVCGLKECHVLTFNSGGAVVDHLVLTTDLEANNYIIKAIWLP GSQTQLALVTSNFVKIFDLSKDLDSPSHYFLVPSGKVRDVTFVNQEGVMNMLCMSSAGHI YWQPLSEESRATLGTFYVTNTLEVLHPEIQDVAGLVGGGGVSIYYSHTLKMLFFSYAQGK SFLAPLNSVEDSVKGTAMITVYGGGGGPKEGGRGKGGAQSLLQWAEVPGHPGLLTALMQA SNNPVVLMLTPAGIHVQEIKVVPAKAKITDMVAVRHWCGAGEQKSTLILLCEDGSLRMYA ADPARTGFWLSGAVQPVHAPRRRARPAKPSHAHTAPRKQHQPTPKTSDGAPQFPIDFFEH CHEMRDAEFGGNDLLQVYNTAQIKHRLNTTGLYVVSTKMSGFTMEITNSDPNTVVCGIRV LLGSQDVARTPTYVEIYGRAVPTMVVRNRWFDIPLSREESLQSDKKLCVVFGPSQDPDGV TMVDSVKIYGKNKEQFGWPEENEDPAACPSSGRVAQEPEGAAGAADGPGAVERLACSALE ALELSAGAAVRSGVSAGADAAADAAESLLCVPASPPLHARAQGLLRAVYQGDYHQRKDRA VLRYVCASLRELRDATDARNVDPEAYFRLVLLARSVAVARPHNLVRFTAPTPEKPADGDW SALWKGDSPGDEPHACALLASVLWKLAACKNQARGPPGILSYGLRHAEHTLHALADIIHA FQLNSDPECVEFGNQIYLSLLLAEDQNISFGAKTALVRVLRPRVRRRRVYIPSPPNTPGA GSSANAARASGSAAEVAASEPELGARREPRYVDVDDSLEPMVLLAPDGGLEALLDIPADA DDETMVELAIALSLQEQEQPRRRRPHTPTAPPPPAPGFSDANASPNGSDDEGSTAATDGS TLRTSPAEAAGSAGEESGGSGADSIGGVSGRSSVYAGPSTSSSQPVASTSRGPEAESETR KLHALRLSLLSAALDALPTLRNLPGERAIPFVQVVLMLAGDLDSSVEGDRALLDLLLEVL IGELDIQSEEPSGEDRDARRDFQSAIARLETPVSEPASADDGAPPVYERTNRRELQLVIM RLLSVLMSRWKTCGSREHAPSASCAAHVSRLAAAAFVRAGAPGHCYGVLAALLPYWRQKN NSNAAASTPTRQLLKPQPPQPLPDMQPFFVKEYVKSHVLDVFDNYPQLLMEMAVRLPYQI HKHCDSSHFDSRWRTLLCEYMMNPQTPLRKQVRKLLLLLCDTRERYRQIRDVHALDTHLN AARALLATDPAYDKLVRLMEHLKACVEIVTPRTGNWQHACRSERRETLPWLLGAARRLHP HVAPTVLQLLQAALCPPGAQPANAAQPAQAGAKDAKAQPEWPKRERSADSDGYVSDASKF QEQRVPDLVAQIHKQVSQEELKLFVKAFLLETNSTAVRWQAHALLLAIYNNSSPNKQASL VALLWSLWPTLPQYGRKAAQFVDLLGYFTLKTSKVDGSEYIDSAVDLLRNQNRLLTSHGN SALYASLGAYVELEGYYLESEPCLVCNNPEVPMATIKLPTIKIDSKFTTTTQIVKLVSSH TISRISLRVGDIKRSKMVRGINFYYNNRTVQAVQELKNKPGMWHKAKRVQLQSGQTEVRV DFPLPIVACNLMMEYADFYENQQATGESLQCPRCSQSVPANPGVCANCGENVFQCHKCRA INYDEKDPFLCHACGFCKYAKFDYTLIARPCCVVDSIENDEERKKTVQTIGTLLDKADRV YRQLIANKPHLESLVHKISEHRVDGRPDENSNTATAAPGGGQVNRVIQALAHKYCVESKG HFEDLSKIIQKVLACRKELVAYDKAQSDRQNGEASPAYSVLAQNYDGDLAKESGGSCYGC SLCTAEHCLTLLRALASQPDKRAALCGAGLVHELVHHNLHRGTPQSQEEVRALICLVTRD NLAATERLCTLLTQRITLSLVGHAASQDHNNSVRPLVLLLGSLVKVQDSIECWEVRLRCV VKLWVWCCPKVSEVAGIPPAAHYILKDEALADMPGINTSSPNSHQFALQQVALPCLRYMQ ELMAPLAAAPSAAPSAAASATDDRVEEVKVRVVESCRVRGRRTTVTPDACPQEGDEPPNR TGDLVVDLAAWLAGRVSRREWRSLAAPEAAPPADCELPPRDLRLARECVGRWRRRVLLGR GMRRVSLSDGGWLRPVMFDPSSRIARDTACRVVASLCDSYERTKAVLILLTSFLPEVGAA GEASEQFLQLYQRLAAKSPWKQFLALRGVLQQIADLMTDEIEQLHRLEETTLTSDLAQGY ALQRLTELLAMFLEEPGARRAYKGRLVGAVLGGYLSLRRLVVQRTRLTDDTQEKLLELLE EMTTGTEAETAEFMAVCIETVQKYPLHDYRTPVFIFERLCSIIYPEENDVGEFFLSLEKD PQQEDFLQGRMLGNPYSSGEPGMGPLMRDVKNKICTDCELVALLEDDNGMELLVCNKIMS LDLPVKDVYKKVWCTLGESLEAMRVVYRMRGLLGDATEEFVETLSQTNAEAVDDEQTYRM ANVLADCGGLEAMLRRLAAIQRVGAARALVSTLLRLLSLCVRVRRCVRVLTSTETRALPV LLHALTLAAAEEKDMPRAELVHQLLEIMERILTVAASESLESFLQFSLTFGGPEHVQALL NCTELTAIRNNSVSLGHLMRVLAALVYGNDLKMAMLVEHFKPALEFERLDAEQWGEREFR IELFCALCANIERNSVGGTLKDYLISLGVVRDALDYIVRHAPCVKPTLVCTDSDELKEFI SRPALKFILRFLTGLASDHEPTQMLVCEKAIPIVHRLEQVSSGEHVGSLAENLLEALRSQ PQCADRVRQVREFTRQEKKRLAMAVRERQLGALGMRSNERGQVTAQCSLTQQVADLAEEA GAVCCICREGYKYQPTKVLGVYTYTKRCPVEEAEARPRKTLGFTTVSHYNVVHVECHMAA VRLQRARDEWESAALQNASTRCNGLLPLWGPNVPESAFASCLARHTTYLQECTGHRDIGY QCTVHDLKLLAWRFARGRTFHDDTGGGGPLSNMQLLPAMLHMALYVMNTTRMAAREANAV NEFLSWAPAKRLESAHEADGALYYATLALLVLPPAEWRRNRAEVLRRLLITGQARCVSSG VPLHALSPEQRVPRPWADLAAYAVFAALVDQLYGVMFKNVSAASAEQWPVKLAEYIRVSD EANAKAAERIVATLTDELLPCTSFAEFCDAAGFLEDFPDPDAFLSTVFEDL NT seq 15636 nt NT seq  +upstreamnt  +downstreamnt atgattactcagtttcttacagtattctcgaaaatggccgccgctggtggatcaatagaa tggtctaccaatgtgaaacctattttaacagcactttatggaccctttttcgacaaaaac gatgcagtggaaataatacaagctattataaaaagtgaaaatgaatttcagaagcatgaa gaagcatacgacttgttttacacatgttttgcttgcctctcagctcattttatcagcatt aatgctaataacatacctccagatcagttaagcacagctcaagatgcttttcgcattatc cttcaacaaatcctcaagaaattgtctgaagctggacagagccaggacgacacttctaat acgctgagcccaaatgtgtctgtcaagcagctgctattgccaattgtggccttatgtggt attgacagcaacggttatctcccttcggatcttgttattttgctggcacttctgaagact gctaagctaccacctcatggaaacgcaaatgaaaatcaaacaacaaagacttcaatatca agtcccataacatctctcacatcaaacacgtctacatcagagaagcaaccgccaacaaat gcccagagacgatctgatgcactgctagaacggctgaccatgccacttcgcagtcaagta tctaatgtattgcctccggttccgtctgccattggagtcacatcaccgtcgagcaaagac agtatcgagagtgctaaggatggaaatgctcaactgtcttccattgatataaagaagtgg gtggcatccacgtgcgcttcgcttctgatggagctgcgagcgggatccacaatattggcc atctgttcgtccctgccgtgcctgcagcgatacttgaaccgctggcagaccgccaaggag tccgattcggcaccgacgtttcattcggacgccgcgctgctgtacttcttggtgaacgag gtggaggtgtgtcgcctggcgctgtccctgccctgcctggagcccttcagtccggagcgg atcgtcaccctcagcgacgtcagcgccgcttggctgctctgcgctaccgcccaggccacc ctccaccaaaaggacgaagagagcgaagcgcagacggcgacgatcgtggagaccgcgctc aacctctacagcaccgtgggagacatcttcaagcagtccacgcgcgccggaggatacgtg taccaaaaccacacgatgatcggggcgtgggtgctcgtctgcggccttcatcacgcgctg ggaggcgcgccgggtcccgtcccgccgggcaagagtcccgccaaagcgggacccctcaga ccctacaatttgaccaaaatgcagcagagcctgggcgtggtgtgggtggcgctgggcgga cgctgcctgtcgtggctcggcgccctgctggccgacgcccgcctcgaggcgctgagctcg ggctcggacggcgccgcgaacaccccggcctcgctccacatctcgactcaccactcggcg caccagagggagctgaggctggccctcgccgctcctctgcaccagttgctggtgaccctc ggcgtagtgtgttaccgcaaggcgacgaacctcaagcgcgccgtggtgccgaaggaccgg gacgccgaagccgagggcgccgccttcttccgggacatgcggctgtgctcggaggactcc gagaccgacgacgaagacagcgaacctctgttcgggctctggttcgagtcgacgctggtg gcgcccgacgccgaagacgacggcctgacccgcctcggcgccgccgaagtcgccgacgcg gcgcccgacgcgaccgagcggggcatcgtgcccgacaaggctgaaccttactcgtacata ttgctcgcgaccgacgtgttcaccctcctgaccgacgagataatcggcggcggcttcgag cgcctcggcggctacgctctccggctgcacgaggcccaccacgccctgttggccgcgctg gcccgagacctggacagggagagcgccaggaccgacacgggaacgatctcgccgtgtttc ggcgcccgtctgggcgcgctctactcggcgttcagttcggcgctggtgcgatatctccac acgctgagcggctccccggccttcgccgcctcgaggccttcgctgcagcagcaactcgcg tccgcggagcgacccaacaccgtccctctacaggtggggccgcgcgtggtgaagctgctc ggcggcatggtgctgagcaagccggcttcggagagagagaacagtatcctggtgatgtgg cacaacctcgtcaataccctgcaagagtacgccttgcagccgccctcgcaggaccacgac tacgaagatctcaacgtcgaacacgctcagctcatggtgtacctgtttcactcgttgacg ctgatgcagaagaagtccgtcctgctctccaccgccaacgccatcatcaaggtggtggag acgctgggcgtaaacgacaggcagcgcgcgacggacctggctccgcaccggctgacgctc gcgaccaggctgatgctgcttctggagtacctcatgaaacatttatacgacgccccgcag acgctgctgcagcagatcgagtggaacctcgtggtggccacgggcctggcccggccctcg gcggagacctctctcggcgaagtcggaaccggctccgacgccggccagaagacgcgcatt tactgcgaagtgcccttcgtcgagcagacctaccgcaggctgtcgcaggacgagacctcg atgcgacccaagttctacgcgctgaccgacaccaaagtcaacaaccaggagaatccgaag ttcgacgggctggcctgcaacttcgtgctcggcactccgcacaagttgaagtatccggtg ctggtggacgccctcctggccctgctcaactgcgcctgcgtctgcgacagtcggagcaac cgcaccgcggtggcggctcgcgccgcggcgcactactgcttccagaccgcttggaggctc gtgacgagcatgcccccggccactccgcacatggacaagctgcaggccgggacggcggcc gacctgccctcgcctctgccgctgtacgccctcgtgtgggctccccgcgccgacgccaag aaggcgttcaacccctggctcaaggacgcgctcgtcaaacagggcatgtacacgcagtac gccgaaaatcttctggccggagtgagctcgtcgtgcgacaacatcaaatactcggcctgg ctggcctcggagaccatcgagcacctgaagcggaacctccgagacggcctcccggctctc ctcgacgtgatctcttgcgacgcggcgttgatgcgcctcagggtgtgcctggtggacgcg tcctccgcggcggaggcgcaccccttcgtgccgcacctgctgcggctgctcgagaccgtc ctcgcgtgttgcaggtcgagcgcgagcctggaggcgggcgcggccgcggggccggcgacg gaggtggcgctgagcgtgtgcggcgtcgggtccggcgcgggcgccgcgtctccgccccgc ctggggccggcgctgaaggcgctgctgccgagcgacgtcgccgcgctgctcgactcccgc tcggcggacccggcttcgacggtcgcgccgtccgagggcgccgtgctcgagctggtgtcc gcgcactgcgagctgatgagcgacagggccgcctacggcgtcgggccatctctggcgatg ctggctcgctcggccgccagactcctggagatcggcgcggccgagatcgccgatagcctc gagctgacgaggaagacgttggcgctcatcgtccccgctctgaccgacggacgcctcgag ttcctggcggagccgttgacggccactctgcactcgatcgtgccccaggccgtcaaggcg gaggagatcgtccacgagcacatcctgcggaccacgtaccccgcgctctgcgcctacgcc ccctccgcggaggggacgctcgtgcacatcgtgaggtattgggaggagatcctggatcgt ccggccggtcgcgccgcctacgaggccgtgttcgtcgaaggagacggcgagttcgtgctc gggaggatccttctgtcggcgcccgacaccagcaatcctttcaccgatcgcgtcgtcaag ctgttcatcaagatattcgcgggctgcgaatcggaagacgtgagccgaagcctgtgcgtc ggggtgtgcaagttcatcggcgtcgccgaccgacggagcctgctggacctcctcggccac atctgcatttacgcaccgaccctcgcgacggtcggcacggccgacggcagtcccgcgggg acggaactcccgactccgacgggctcggcccccgacggccaccccgcctcgctcgccctg cgcaacgccatccgctgcgtgctcttccgcaccgacggcgacgccgccccgcgcccggac ctgcccgtcttcgagaatcctgtcgcggcgactccggctccgggggctcaatcggagacg aacgcccaacaatctggaaattcagagacgtgcagctggtcggactgcagcaaggacagc gcgggggcccccgggacgggcgcgggggcgacccgcgccgaggcgagttcgcccgtgggc gagggcacccacgccgcccttctcacggcgctctgcaagcacgtcgtcctgcactgcgaa gaggaggcgagcgagcggatgctggggactctgatcgaagtgagcggcgaaggctgtcct cctccgctgcttcgagagatgtgccgcctcgcggactcgcactcgggcacgctgcacgag cttctcttcccggccgcgctggcgtggctgtcctcccgcgtcgagagtctctgcagcccc gaggtgctggagaagttagaggagggcacgatcgacaacgagaagacgtcgccgcagata gagtccgcgtgtacgctgctgtcgtacttgggcgacgccttgcacgctatcggcgctccg ccctcgcacgcgtggcgatcggtcagcccgacctgggagtctccttccgacctcggcttc gacttggactacgccgacgaacaacaagacgacgacgacacgagcgccgacgattccgac gaggacgcggtgctcaccaacaagctgtgcaccttcaccgtaacgcaacgcgagttcatg aaccagcactggtaccactgccacacgtgcaagatggtggacggcgtcggagtgtgcacg gtctgcgcgagggtgtgccaccgcggtcacgacatctcctacgccaagttcggcaacttc ttctgcgactgcggagccaagccggacttcagctgccaagccctggtgaagcgcgagaag tcttcgggcggcggtcgccccgccgaggaggcgcccccggcgccgtccctgcgccgtcga ccctccagccccacgcccgccgctttgctggccccgcccaggaggcccgtgctggctcac aacattcagggttgccgaagtttcctggcgagctacggaaagtgggagtggtgcctcgaa cgcgtgcgcacgctgctgtgcgcgctggcgggccccgtgcgcgccgcgtgtgagcggacg gccgcggtcggagcgcacggtcgagcgcagagggcgctggcgcaactccacctgggcgaa aagaagttctcgcacacggactcgctcatgctgcccaccctaggttctcaagaaggcgcc ttcgaaaacgtgcgaatgtcgtacacgggagagaacggtcagaccatcagacagctgata tcggcgcacaagctgcgccgcgtggccatgtgctgcttggcttcgccgcagggccggagg caacacctcgccgtctcgcacgagaaaggcaaaataacggtgctccagctgtcggccctc ctgaagcaagcggactcgtcgaagcacaggctgaccctgactcggctgtcttcggccccg atcccgttcaccgtgctcagtctgagcgggaacgcggccaacgaggacctcctggccgtg tgcggcctcaaggagtgccacgtgctcaccttcaactctggcggagccgtggtggatcat ctggtgcttacgaccgacctggaggcgaacaactacataattaaagccatctggctgccg ggctcgcagacgcagctcgcgctcgtcacgtcgaacttcgtcaagatattcgatctcagc aaggacctcgacagtccctcgcattacttcctcgtgcccagcggaaaggtccgcgacgtg acgttcgtgaaccaagagggagtgatgaacatgctctgcatgagctcggcgggtcacatc tactggcagccgctgagcgaggagtctcgggcgacgctcggcaccttctacgtcaccaac accttggaagtgttgcacccggagatacaggacgtcgcggggttggtgggcggaggtgga gtttcgatctactactcgcacactctgaagatgctcttcttctcgtacgcgcagggaaag agctttctcgccccgctcaattcggtcgaagacagcgtcaaaggcaccgccatgatcacg gtgtacggcggaggggggggccccaaggagggcgggcgcggcaagggcggcgcccagtct ctgctgcagtgggccgaagtgcccggacacccgggcctgctcacggccctgatgcaggcc tccaacaaccccgtcgtgctcatgctcacgccggccggaattcacgtgcaagagatcaag gtggtgccggccaaggcgaagatcaccgacatggtggccgtgcggcactggtgcggcgcc ggcgagcagaagagcacgctgatcctgctgtgcgaggacggcagcctgcgcatgtacgcc gccgatcccgcccggacgggcttctggctctccggcgccgtgcagcccgtgcacgcgccg cgcaggcgcgcccgccccgccaagccctcgcacgcgcacaccgctccccggaagcagcat cagccgacgccgaagacgagcgacggcgctccccagttcccgatagacttcttcgagcac tgccacgagatgagggacgccgagttcggcggcaacgacctcctgcaggtgtacaacacg gcgcagatcaagcatcggctgaacaccaccggtctctacgtcgtgtcgaccaagatgagc ggtttcacaatggaaatcacgaactccgaccccaacacggtcgtgtgcgggattcgagtc ctgctcggcagccaggacgtcgccaggaccccgacttacgtcgaaatatacggcagagcg gtcccgactatggtggttcgcaatcgatggttcgacattcctctctcgagagaagagtcg ttgcaatccgacaagaagctctgcgtcgtcttcggtccctcgcaagatcccgacggcgtc accatggtggattccgtgaagatctacggaaagaacaaggagcagttcggttggccggag gagaacgaagacccggccgcctgtccgtcttccggcagagtggctcaggaacccgagggc gcggcgggcgccgccgacgggcccggcgccgtggagcgtctggcgtgctcggcgctcgag gcgctggagctgagcgccggcgcggccgtccgctcgggcgtctcggcgggagcggacgcg gccgcggacgccgccgagagcctgctgtgcgtgcccgcctcgccgccgctgcacgcgagg gcccagggcctcctgcgcgccgtctaccagggcgactatcatcagcgcaaggaccgggcc gtgctgcggtacgtatgcgcctccctgcgagagctgcgcgacgcgacggacgctcgcaac gtggaccccgaggcctacttccgcctcgtgctcctcgctcgctcggtggccgtcgcgcgt ccgcacaacttggttcgattcacggcgccgacgcccgagaagcccgccgacggcgactgg tccgccctgtggaagggagactcgccgggcgacgagccgcacgcgtgcgccttgctggcg agcgtgctctggaagttggcggcctgcaagaaccaggctcgaggcccccccggcatcctg tcttacggcttgagacacgccgagcacaccttgcacgccctggccgacatcatacacgcg ttccaactcaactccgacccggaatgtgtcgaattcggcaatcaaatctatctgtcgctc ctcctcgccgaagaccagaacatcagcttcggcgcgaagacggctctcgtgcgagtgctg cgacctcgggtgaggaggcgacgcgtctacattccgtctccgccgaacacgccgggagcc ggctcgtcggcgaacgccgctcgcgcgagcggctcggcggccgaggtcgcggcctcggag cccgagctcggcgcgcggcgggagcctcgatacgtggacgtcgacgactcgctcgaaccg atggtgctgctggcgcccgacggaggtctcgaggcgctgctggacattccggccgacgcg gacgacgagacgatggtggaactggccatcgcgctgtcgctgcaggagcaggagcagccg cggaggcggcggccgcacacgcccacggcgccgccgccgcccgcgcccggcttcagcgac gccaacgcctcgcctaacggctcggacgacgaaggcagcacggcggcgacggacggcagc accctgcggacgtcgccggccgaggccgcggggtcggccggcgaggagagcgggggttcc ggcgccgacagcatcggcggagtgtccggccgcagcagcgtatacgccgggccttcgact tcgtcgtcgcagccggtggcgtccacgtcccgcggccccgaagcggagagcgagacgcgc aagctgcacgcgctgcgcctgtctctgctgtccgccgcgctggacgccctgccgaccctc aggaacttaccgggagagagagccattccgttcgtccaagtggtgctgatgctcgccggc gacttggattctagcgtcgaaggagacagagcgctcctggatctcctgctggaggttctg atcggcgagctcgacattcagagcgaggagccctccggcgaagatcgcgacgctcgacga gacttccagtcggccatcgccaggttggaaacgccggtctcggaaccggcctccgccgac gacggcgccccgcccgtctacgagaggaccaatcgcagagagctgcagctcgtcataatg agactgctgagcgtgctcatgagccggtggaagacctgcgggtcccgcgagcacgcgccc agcgcgtcgtgcgcggcccacgtgtcgcgattggccgcggccgccttcgtgcgcgccggc gcccccggccactgctacggcgtgctggccgcgctgctgccctactggcggcagaagaac aacagcaacgcggccgcctcgactcctacgcgacagcttctcaaacctcaaccgccgcag ccgctgcccgacatgcagccgttcttcgtcaaggagtacgtcaagagtcacgtgctggac gtattcgataactacccgcagcttttgatggaaatggcggttcgtcttccgtaccagatc cacaagcactgcgattcctcgcatttcgattctcgctggcgcactcttctctgcgagtac atgatgaatcctcagacgccgctcaggaaacaagtccgcaagctcctgctgctcctgtgc gacactcgagagcgctaccgtcagatacgcgacgtgcacgcgctcgacacgcacctgaac gccgcgcgggcgctgctggccacggaccccgcctacgacaagctggttcggctcatggag catctcaaggcgtgcgtggagatcgtgacccctcgaaccggcaactggcagcacgcgtgc cgctcggagcggcgcgagaccctgccgtggctgctgggcgcggccagacgcctgcacccg cacgtggctcccaccgtgctgcagctgctgcaggcggcgctgtgcccgcccggcgcccag cccgcgaacgccgcccaaccggcccaggccggcgccaaggacgccaaggcgcagcccgag tggcctaagcgcgagcgcagcgccgacagcgacggctacgtgtcggacgcctccaagttc caagagcagagagtgcccgacctcgtggcccagatacacaaacaggtgtctcaggaagaa ttgaaacttttcgtgaaggccttccttctggagaccaattcgaccgcggttcgttggcaa gcgcacgcgctgctattggccatttacaacaactcgtctccgaacaaacaagcgtctctg gtggcgctgctctggagtctgtggcccacgctgccgcagtacggacgcaaggcggcgcaa ttcgtcgacctgctcggctacttcacgctcaagacctcgaaggtcgacggctcggagtac atcgacagcgcggtggacctcctgcgcaaccagaaccgtctgttgacgtcccacgggaac tcggctctgtacgcgtctctgggagcgtacgtggagctcgagggctactacctggagtcg gagccctgtctcgtgtgcaacaacccggaggtgcccatggccaccatcaagctgcccacg ataaagatcgactccaagttcacgaccacgacgcagatcgtgaagctggtgagcagccat acgatcagccgcatcagcctgcgcgtcggagacatcaagcgcagcaagatggtgcgcggc atcaacttctactacaacaaccgcaccgtgcaggccgtgcaggagctcaagaacaaaccc ggcatgtggcataaggccaagcgcgtccagctgcaatccggacagaccgaagtgcgggtg gacttcccgctgccgatagtcgcctgcaacctcatgatggagtacgccgacttctacgag aaccagcaggccaccggggaatctcttcagtgccctcgctgctcgcagtcggtgcccgcg aatcccggggtgtgcgctaattgcggcgaaaacgtcttccaatgtcacaagtgccgggca ataaactacgacgaaaaggatccgttcctgtgtcacgcgtgcggcttctgcaagtacgcc aagttcgattacactctgatcgccagaccctgctgcgtcgtcgattccatcgaaaacgac gaggaacggaagaagaccgtgcagacgatcggcactctgctggacaaggccgaccgcgtc taccgccagctgatcgccaacaagccccacttggagtcgctcgtgcacaagataagcgag caccgcgtggacggtcggccggacgagaacagcaacacggcgaccgcggccccgggaggg ggtcaggtcaaccgcgtcatccaggcgctcgcgcacaagtactgcgtcgagagcaagggg cacttcgaggacctctccaagatcatccagaaggtgctggcctgcaggaaagaattggtc gcctacgacaaagctcagagcgaccgacaaaacggcgaggcgtcgcccgcgtactccgtg ctcgcgcagaactacgacggcgacctcgccaaggagagcggcggctcgtgctacgggtgc tcgctgtgtacggcggagcactgcctgaccctgctgcgggccctggcgtcgcagccggac aagagagccgcgctgtgcggcgccggcctcgtgcacgagctcgtgcatcacaatctgcac cgcggcacgccgcagagccaggaagaggtgcgcgccctgatctgcctggtgactcgagac aacttggcggccacggaacgcctgtgcactctgctgacgcagcgcatcactctgtcgctc gtggggcacgccgcctcgcaggatcacaacaactccgtgcggcccctggttctcctcctg ggatcgctggtcaaagtccaggactcgatcgaatgttgggaggtgaggctgcgatgcgtc gtgaagctgtgggtctggtgctgcccgaaagtgagcgaagtggcggggatcccgccggcc gcccactacatcctcaaggacgaggcgttggccgacatgcccggcatcaacacctcctcg cccaactctcaccaattcgcccttcaacaagtggccctgccttgtctccgctacatgcaa gagctgatggctccgctcgccgccgcgccgtccgccgccccgtccgccgcggcctccgcg acggacgatcgagtcgaggaagtcaaggtacgcgtcgtcgaatcgtgtcgtgtacgcggt cgccggacgaccgtaacgccggacgcgtgtccgcaggagggagacgagccgccgaatcgg acgggcgacctcgtcgtcgacctggcggcgtggctggccggccgagtgtcgcggagggag tggcgcagcctggccgccccggaggccgcgccgcccgccgactgcgagctgccgccgagg gacctgcgcctggcgcgcgagtgcgtcggccggtggaggcgccgggtgctgctcggccgc ggcatgcggcgcgtcagcctgtcggacggcggctggctgcggcccgtcatgttcgacccc agctcccgcatcgcgagggacacggcctgccgagtcgtcgcctcgctgtgcgactcctac gagcggaccaaggcggtgctgatactgttgacgagcttcctgcccgaggtgggcgcggcc ggggaggcgagcgagcagttccttcagctgtatcagcgtctagccgcgaagagcccgtgg aagcaattcctggcgctgcggggcgtgctgcagcagatagcggatctcatgactgacgag atcgagcagctgcaccgcctcgaggagaccacgctcacctcggacctggctcaaggatac gctcttcagcgtctcacggagttgttggcgatgttcctggaggagccgggggcgcggagg gcgtacaaaggccggctggtgggagccgtcctcgggggctacctctctctgcgtaggctg gtggtacagaggacccgcctcacggacgacacgcaggagaagctgctggagctgctcgag gagatgaccaccggcaccgaagcggagacggccgagttcatggcggtgtgcatagagacc gtgcagaagtacccgctgcacgactaccgcactccggtgttcatcttcgaacggctctgc tccatcatctacccggaagaaaacgacgtcggcgaattcttcctctctctggagaaggat ccgcagcaggaggacttcttgcagggccgcatgttgggcaacccgtactcgtcgggagag ccgggaatggggcccctgatgcgcgacgtcaaaaacaagatctgcacggactgcgagctc gtggctctgctggaagacgacaacggcatggagttgctcgtctgcaataagatcatgtcc ctggacttgcccgtcaaggatgtctacaagaaggtgtggtgcacgttgggagagagtctg gaggcgatgcgcgtcgtgtaccggatgagaggccttctcggagacgccaccgaagagttc gtggagacgctcagccagaccaacgccgaagccgtcgacgacgagcagacgtaccgcatg gccaacgtgctggcggactgcggcggcctggaggcgatgctgcggcgtttggcggcgatt cagcgagtgggcgccgcgcgagccctcgtgtcgaccctgctgcgcctgctgagcctgtgc gtgcgcgtgcgccgctgcgtgcgcgtgctgacgagcacggaaacgcgcgccctgcccgtc ctcttgcacgcgctcacgctcgccgccgccgaggagaaggacatgcccagggccgagctc gtgcatcaactgctcgagataatggagcgcatactcaccgtggcggccagcgagagcttg gagtctttcctgcaattctcgctcacgttcggcggcccggagcacgtgcaggccctgctc aactgcaccgaactgacggcgatccgcaacaactccgtgtctctcggccacctgatgcgc gttttggccgcgttggtctacggcaacgacctgaagatggcgatgctggtggagcacttc aagccggcgctggagttcgagcgcctcgacgccgagcagtggggcgagcgcgagttccgc atcgagctgttctgcgcgctctgcgccaacatcgagaggaacagcgtcggaggcacgctc aaagactacctgatctcgctcggcgtcgtccgcgacgccttggactacatagtgagacac gcgccgtgcgtgaagccgacgctggtctgcaccgactccgacgagctgaaggagttcata agccggccggctctgaagttcatcctgaggttcctcaccggcctggcttccgaccacgaa ccgactcagatgctggtgtgcgagaaggcgatcccgatagtgcatcggctcgagcaggtg tcctccggggaacacgtgggctccctggccgagaaccttctcgaggcgctccggtcgcag ccgcagtgcgccgacagggtgcggcaagtgcgggagttcaccagacaggagaagaagcgc ctcgcgatggccgtgcgcgagcggcagctgggcgcgctgggcatgcgcagcaacgaacga gggcaggtgacggcgcagtgctcgctcacgcagcaggttgccgacctggccgaggaggcc ggcgccgtgtgctgcatttgccgcgagggatacaagtaccagcccacgaaggtgctgggc gtctacacttacacgaagcgctgccccgtggaggaggcggaggcgcgcccgcgcaagacc ctcggcttcacgacggtctcgcactataacgtcgtccacgtcgagtgccacatggccgcc gtgaggctgcagcgcgccagggacgagtgggagagcgccgccctgcagaacgccagcact cgctgcaacggcctgctgccgctgtggggacccaacgtgcccgagtcggccttcgccagc tgcctcgcccgacacaccacctacctgcaggagtgcacgggccaccgcgacatcggctac cagtgcacggtgcacgacctgaagctgctcgcgtggcgcttcgcccgcggccgcactttc cacgacgacacgggcggcggaggcccgctctccaatatgcagctgctgccggcgatgctg cacatggccctctacgtcatgaacaccacccgcatggcggctcgcgaggccaacgccgtg aacgagttcctgtcctgggcgccggccaagcgcctcgagtcggcccacgaggcggacggc gccctctactacgcgacgctcgcgctgctggtcctgccgcccgccgagtggcggcgcaac cgcgcggaggtgctgcggcggttgctgatcacggggcaggcgcgctgcgtgtcgagcggc gtgcccctgcacgcgctgtcgcccgagcagcgcgtcccgaggccctgggccgacctcgcg gcctacgccgtgttcgccgccctcgtcgaccagctgtacggggtcatgttcaagaacgtg tcggcggcctccgcggagcagtggcccgtgaagctggcggagtacatccgcgtgagcgac gaggccaacgcgaaggcggccgagcgcatcgtggcgacgctgaccgacgagctgctgccc tgcacctccttcgccgagttctgcgacgcggccggcttcctcgaggacttccccgacccc gacgcgtttctctcgaccgtcttcgaagacctctga

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