Pseudarthrobacter oxydans: SMD14_08025
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Entry
SMD14_08025 CDS
T09608
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pok
Pseudarthrobacter oxydans
Pathway
pok00300
Lysine biosynthesis
pok00550
Peptidoglycan biosynthesis
pok01100
Metabolic pathways
pok01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pok00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SMD14_08025 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SMD14_08025 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SMD14_08025 (murF)
Enzymes [BR:
pok01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SMD14_08025 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
CbiA
Motif
Other DBs
NCBI-ProteinID:
WPU10924
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Position
1768516..1769982
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AA seq
488 aa
AA seq
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MIAFTAAEIADITKGRLDADPGITPLSVVTDSREATPGSLYVAKPGEYADGHDFVEAAFT
AGASLALVERPVAAPDGSPYPSVVVPDAVLAMGALAAEAVRRIRAARAEANEELTVIGIT
GSAGKTTTKDLLAGILSRHGATVAPRGSYNGEIGVPLTVFTAGTDTRYLVIEMGATGIGH
IRYLAEMVRPDIGVVLGVGTAHAGEFGGVENIARAKGELVEGLAASGTAIINLDDERVAD
MRARTSASVVGFSAEGRPGAGVQALNADTNAEGHPEFELLLPGADTTHHVSSRLIGAHHV
SNLLAAAAAAWAAGIPGPDIAAALSGQTAASRWRMERTEREDGVTIINDAYNANPESMRA
ALRTLADLGQGRRTWAVLGAMLELGEDSIREHTAVGTQVVRLNISRLVVVGREARALYVS
AVQEGSWGDECVFAETADDAYELLSAELKPGDLVLFKSSNSVGLRHLGDRIALPPQTPQP
ADERSTQL
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgattgcatttaccgcggcggaaatcgccgacatcactaaagggcgcctggacgccgat
cccgggatcacgcctctgtcggtggtcaccgattcccgcgaagccacgccgggatcgctc
tacgtcgcaaaacccggcgagtacgcggacggacacgacttcgtcgaagccgccttcacc
gccggtgccagcctggcactagtggagcgcccagtggcagcaccggacggttcgccgtat
ccgtccgtggtggttcccgacgccgtgctcgcgatgggcgcgctggccgcggaagccgtc
cggaggatccgtgccgcccgcgcggaggccaacgaagaactgactgtcatcggcatcacc
ggctctgccggaaagaccaccaccaaggacctgcttgccggcatactttcccggcacggc
gccactgtggcgccgcgggggtcctacaacggtgaaatcggagtgccgctcaccgtcttc
accgccggaaccgacacccgctacctcgtgatcgagatgggcgccaccggcatcggccac
atcaggtacctggccgagatggtcaggcctgacatcggagtggtgctcggcgtcgggacc
gcgcacgccggcgaattcgggggagtggagaacatcgcccgagccaagggcgaactcgtg
gaaggcctggcagcctccggcacagccatcatcaacctcgacgacgagagggtggcggac
atgcgcgcacgcacctccgcgtccgtcgtcggcttctccgccgaaggccggcccggcgcc
ggcgtgcaggcgctcaatgcggacaccaacgcggagggccaccccgaattcgaactcctc
cttcccggtgcggacacgacccaccacgtcagcagccgcctgattggtgcccaccatgtc
agcaatttgctggcagcggccgcagccgcgtgggcggcaggaattcccggcccggacatc
gccgcggccctcagcggccaaacggcagccagccggtggcgcatggagcgcaccgagcgg
gaggacggcgtcaccatcatcaatgacgcctacaacgccaacccggagtcaatgcgcgcg
gccctgcgcacactcgcggacctgggccaaggaaggcgcacctgggcagtcctgggcgcc
atgctcgaactcggcgaggattccatccgcgagcatacggccgtgggcacccaggtggtg
cgccttaacatttcccggctggtggtagtgggccgggaagcccgtgccctctacgtatcc
gccgtccaggagggctcctggggtgacgaatgcgtcttcgccgagaccgccgacgacgcg
tacgagctgctgtcagcggaactcaaacccggcgacctggtgctgttcaaatcatccaac
agcgtgggacttcgccatttgggcgatcggatagcattacccccacaaaccccgcagccc
gccgatgaaaggagcacacagctgtga
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