KEGG   Polaromonas sp. JS666: Bpro_0273
Entry
Bpro_0273         CDS       T00343                                 
Name
(GenBank) branched-chain alpha-keto acid dehydrogenase E1 component
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
pol  Polaromonas sp. JS666
Pathway
pol00280  Valine, leucine and isoleucine degradation
pol00640  Propanoate metabolism
pol00785  Lipoic acid metabolism
pol01100  Metabolic pathways
pol01110  Biosynthesis of secondary metabolites
pol01210  2-Oxocarboxylic acid metabolism
Module
pol_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:pol00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    Bpro_0273
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    Bpro_0273
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    Bpro_0273
Enzymes [BR:pol01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     Bpro_0273
SSDB
Motif
Pfam: E1_dh OxoDH_E1alpha_N ZapG-like DUF4377
Other DBs
NCBI-ProteinID: ABE42238
LinkDB
Position
288986..290251
AA seq 421 aa
MNKNQVLRLHVPEPSGRPGHETDFSYLHLSPAGAVRRPPVEASPADTSDLAYSLVRVLDD
DNRAVGPWVPPVEPQRLRQGLRAMMKTRIYDARMLIAQRQKKISFYMQCLGEEAIATAHA
LALQPGDMCFPTYRQQGLLLARDDVDMVEMICQLMSNERDPLKGRQLPVMYSYKRAGFFT
ISGNLATQFIQAVGWGMASAIKGDSKIASAWIGDGATAEADFHTALTFAHVYRAPVILNV
VNNQWAISTCQAIAGGEATTFAARGVGCGIASLRVDGNDFLAVYAASLWAAERARSNLGP
TLIEWVTYRGGAHSTSDDPSRYRPVDDWAHFPLGDPIARLKAHLMQTGAWTEQEHEATQK
ELEAQVSAALKEAERYGSLADGHLAGAAAMFEDVYKDMPEHLRRQREQLLRGEMDTPRRE
A
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgaacaagaaccaggtgctacgtctgcatgtgccggagccttcggggcgccccggccac
gagaccgacttttcctatctgcatctgtcaccggccggcgcggtgcggcgcccgcccgtg
gaggcctcccccgccgacaccagcgacctggcctacagcctggtgcgggtgctggatgac
gacaaccgcgccgtggggccctgggttccgccggtggaaccgcagcggctgcgccagggt
ctgcgcgccatgatgaagacgcgcatctatgacgcccgcatgctgatcgcgcagcggcag
aaaaaaatctcgttttacatgcagtgcctgggcgaggaggcgattgccaccgcgcatgcg
ctggcgctgcagcccggcgatatgtgttttcccacctaccgccagcaggggctgctgctg
gcgcgcgacgacgtcgacatggtcgagatgatctgccagctgatgtccaacgagcgcgat
ccgctcaaggggaggcagctgccggtgatgtactcgtacaagcgggccggattttttacc
atttcgggaaacctggccacgcagttcatccaggcggtgggctggggcatggcgtcggcg
atcaagggcgactctaaaatagcctcggcctggattggcgatggcgccaccgccgaggcc
gacttccataccgcgctgactttcgcccatgtgtaccgcgcgccggtcattctcaacgtg
gtcaacaaccagtgggcgatctccacctgccaggcgattgccggcggcgaggccaccact
tttgctgcgcggggtgtcggctgcggtattgcctccctgcgcgtggacggcaatgacttt
ctcgctgtctacgccgcttcgctgtgggccgcggagcgcgcgcgcagcaacctggggccg
acgctgatcgagtgggtcacctaccgcggcggggcgcactcgacctcggacgatccctcc
cgctaccgccccgtcgacgattgggcgcactttccgctgggcgacccgatcgcgcggctc
aaggcacacctgatgcagacaggcgcatggaccgagcaggagcatgaagccacgcagaag
gagctggaggcccaggtgagcgcggcgctgaaggaggccgagcgctacggctcgctggcc
gacggacacctggccggcgcggcggcgatgttcgaggatgtctacaaggacatgccggag
catctgcgccggcagcgcgaacaactgctcaggggtgaaatggacacccccaggcgggag
gcctga

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