Polynucleobacter sp. SHI8: PSHI8_01770
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Entry
PSHI8_01770 CDS
T10387
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
poln Polynucleobacter sp. SHI8
Pathway
poln00300
Lysine biosynthesis
poln00550
Peptidoglycan biosynthesis
poln01100
Metabolic pathways
poln01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
poln00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PSHI8_01770 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PSHI8_01770 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PSHI8_01770 (murF)
Enzymes [BR:
poln01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PSHI8_01770 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BDW12541
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Position
168388..169869
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AA seq
493 aa
AA seq
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MSHYLTLEKMSQMVPGSRLLNVSSAMMHSPIDNLSTDSRKIQSGDFFIAIAGEKFDGNQF
LKEVCKKGSLAALASKEECVPENFPVLLVEDTLKALQMIATAWRKELNPQLILVTGSNGK
TTVKEMIASILKEALGEKHVLATPGNLNNDIGLPLTLLGLRAHHQIAVIELGMNHPGETQ
FLASIAQPNIVLINNAQREHQEFMHTVEAVALEHADAISQLQENGVAIFPADSEYTEIWK
SKSNGYTYLDFSLSENLKESLGQVVGCWKSQSHLRIELPENKQHPKTGIEVKLATLGDHN
AKNAIAAATVAFAANINHEAICRGLEKFMPVAGRMRSHSLPSFGELGQLVDDTYNANPDS
VIAAIDVLAQLPGTRWLVLGDMGEVGNQGQQFHHEIGKYAKDKGIEHLYATGELSTYAIE
GFKTQIQAQPLAKEAQGIHFHEPKALLKQLKADLQTFQHHFSTGHVAILVKGSRFTKMER
IVNCLLKEESLCF
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgagtcattatttgacccttgagaaaatgtcgcagatggtgcccggatcacgcttactc
aatgtgagctctgccatgatgcactcgcctattgataacttatcaacagacagtcgaaaa
attcagtctggagattttttcatagcgattgctggcgaaaaatttgatggtaatcaattt
ttaaaagaagtatgtaaaaaaggttcactagccgcattagcgagtaaagaagaatgtgtt
cctgagaattttccagtcctactagtcgaagatactttaaaagctttgcaaatgatagca
acagcttggcgaaaagagttaaatcctcaattaatattagtaacgggtagtaatggtaaa
accaccgtgaaagagatgattgccagtatcttaaaggaagccctaggcgaaaagcacgtc
ttagcaactcctggcaatttaaacaacgatattggtttgcccctgactctgttaggactt
cgagcacatcatcaaattgccgtgattgaactaggcatgaatcaccctggcgaaacacag
tttttagcaagtattgcgcaacctaatattgtgttgattaataatgctcaacgagagcat
caagaatttatgcatacggttgaagctgtagctttagagcacgcagatgccatatcgcaa
ttacaggaaaacggtgttgctatatttccggcggattctgaatatacagagatatggaaa
agtaaatctaacggatatacctatttagatttttctttaagtgaaaacttgaaagagtca
ttgggacaagttgtaggatgttggaagagtcaaagtcatttacgtattgagttaccagaa
aataagcaacatccaaaaacagggattgaagtcaaactagcgacgctaggtgaccataat
gcaaagaatgctattgcagccgctacagtagcatttgcggcaaatatcaatcatgaagct
atctgtcgtggattagaaaaatttatgccagtagctggcagaatgcgtagtcattcatta
ccgagttttggcgaacttgggcaactggtcgacgatacctacaatgcaaatccagattca
gtaattgctgcgattgatgttcttgctcaattgccgggaacccgttggttagtgcttgga
gatatgggcgaggttggtaatcaaggtcagcagtttcatcatgaaattggtaaatatgcc
aaggataaaggcattgaacatctatacgctaccggtgaattatcaacttatgcaattgag
ggtttcaagacacaaatacaggcacagccgctagcgaaagaagcgcaaggaattcatttt
catgaacctaaggcattgctcaagcaattaaaagctgatttacaaacatttcaacaccat
ttttcaacggggcatgttgcgattttagtaaaaggctcacgctttaccaagatggaaaga
atcgttaactgcttattgaaagaggagagcttatgtttctag
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