Polynucleobacter sp. TUM22923: TUM22923_01600
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Entry
TUM22923_01600 CDS
T10645
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
polt Polynucleobacter sp. TUM22923
Pathway
polt00300
Lysine biosynthesis
polt00550
Peptidoglycan biosynthesis
polt01100
Metabolic pathways
polt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
polt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TUM22923_01600 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TUM22923_01600 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TUM22923_01600 (murF)
Enzymes [BR:
polt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TUM22923_01600 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BDX20839
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Position
151944..153407
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AA seq
487 aa
AA seq
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MSPFITKPMTTLSRMQAMLPGSQLLHIAPEDAKTLSISRVSSDSRKVQAGELFISLVGDR
FDAHDFLDDVESAGASAALVSSLDKCPKHLPAVCVPDVRKSLGQLAQAWRAQFSIPVALV
TGSNGKTTVKEMIASIFKGAVGLDQVLVTQGNLNNDIGLPLTLLRMRESDRLAVIELGMN
HPGETAQLAAIAQANIAVINNAQREHQEFMATVEAVAIEHATALSALPINGVAVFPADSE
FTSLWRQASVDRKVIDFAFATDHQVISASVTGSSLSNGKVEIQTEQGVIEVRLNTLGDHN
IRNALAASAVALGAGLSLENIKTGLESFSPVNGRMQSKYLSAQRTLIDDTYNANPDSVCA
AIDSLKRSGNISWLVLGDMGEVGDQGPAFHEEVGAYAAECGIAQFFALGEQSHFAAQGFN
KIKNERALTSHAFHFMDIDQLLEVMSTQLGALPNSQDQQLDILVKGSRFMRMERVVQALL
EEAKTCS
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
gtgagtccattcattacaaagccaatgactacgctatctcgaatgcaggcaatgctacca
ggcagtcagctgctccacatcgcacccgaagatgccaaaacattatcaatttcgcgagta
agtagcgatagtcgaaaggttcaggcgggtgaactgttcattagcttggtaggcgatcga
tttgatgcccatgattttttggatgatgtggaaagtgcgggcgctagtgctgcacttgtt
tccagtctagataagtgtccaaagcatcttccggcagtatgcgtcccagatgttagaaaa
agcttgggtcagctggcacaagcatggcgtgcacagttttcgattccagtagcccttgtc
actggctccaatggaaaaactactgttaaagaaatgattgcctctatatttaagggggca
gtaggcttagaccaggtgcttgtgactcagggaaacttgaataatgatatcggtctgcca
ttgaccctcttgcgtatgcgcgagagcgatcggttggctgtgattgagttggggatgaat
catcctggtgagactgcccagctagctgctattgcacaagccaacattgcagtaatcaat
aatgctcaacgtgagcatcaagaattcatggctacagtcgaggcggtcgcaatcgagcat
gcgactgcgctgagcgcattaccgattaatggcgtggcagtttttccggcagattctgaa
tttactagtctatggcgtcaagcctctgtggatcgtaaggtgatagattttgcttttgca
actgatcatcaagttattagcgcatcagtaacgggctcatccctatccaatggaaaagtt
gaaattcaaactgagcaaggcgttattgaggttcgactcaatacgctgggcgaccataac
atcaggaatgcgcttgcagctagtgccgttgctttgggtgcgggccttagtcttgaaaat
attaaaacaggcttagagtctttttccccggttaacggcaggatgcagtctaaatactta
agtgcacagcgtacgctgattgatgacacttataacgctaaccctgattctgtttgtgct
gcgattgattcactaaagcgatcaggaaatatatcttggctcgtgttgggtgatatgggt
gaagtcggagatcaaggccctgcttttcacgaagaggttggagcttatgcagctgaatgc
ggaattgctcaattctttgcattaggggagcaatctcattttgcggcgcagggttttaat
aagatcaaaaatgagcgggcgctcacttctcacgcatttcactttatggatattgatcaa
ttactagaggtaatgagcactcaattgggagcgctgcccaacagtcaggatcagcagttg
gatattttggttaaaggatctcgttttatgcgtatggagcgcgtggttcaggctttgcta
gaggaggctaagacatgctcttaa
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