Pongo abelii (Sumatran orangutan): 100137030
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Entry
100137030 CDS
T01416
Symbol
MET
Name
(RefSeq) hepatocyte growth factor receptor precursor
KO
K05099
proto-oncogene tyrosine-protein kinase Met [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04360
Axon guidance
pon04510
Focal adhesion
pon04518
Integrin signaling
pon04520
Adherens junction
pon05100
Bacterial invasion of epithelial cells
pon05144
Malaria
pon05200
Pathways in cancer
pon05202
Transcriptional misregulation in cancer
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05211
Renal cell carcinoma
pon05218
Melanoma
pon05223
Non-small cell lung cancer
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100137030 (MET)
04014 Ras signaling pathway
100137030 (MET)
04015 Rap1 signaling pathway
100137030 (MET)
04020 Calcium signaling pathway
100137030 (MET)
04151 PI3K-Akt signaling pathway
100137030 (MET)
09133 Signaling molecules and interaction
04518 Integrin signaling
100137030 (MET)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100137030 (MET)
04520 Adherens junction
100137030 (MET)
09150 Organismal Systems
09158 Development and regeneration
04360 Axon guidance
100137030 (MET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100137030 (MET)
05202 Transcriptional misregulation in cancer
100137030 (MET)
05206 MicroRNAs in cancer
100137030 (MET)
05205 Proteoglycans in cancer
100137030 (MET)
05208 Chemical carcinogenesis - reactive oxygen species
100137030 (MET)
05230 Central carbon metabolism in cancer
100137030 (MET)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100137030 (MET)
05226 Gastric cancer
100137030 (MET)
05218 Melanoma
100137030 (MET)
05211 Renal cell carcinoma
100137030 (MET)
05223 Non-small cell lung cancer
100137030 (MET)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
100137030 (MET)
09174 Infectious disease: parasitic
05144 Malaria
100137030 (MET)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100137030 (MET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100137030 (MET)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100137030 (MET)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
MET family
100137030 (MET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
TIG
Pkinase
Sema
PSI
Kinase-like
Pkinase_fungal
Linker_histone
Motif
Other DBs
NCBI-GeneID:
100137030
NCBI-ProteinID:
NP_001162038
Ensembl:
ENSPPYG00000017932
UniProt:
Q2IBD8
A0A2J8UPG2
LinkDB
All DBs
Position
6:113794936..113918056
Genome browser
AA seq
1390 aa
AA seq
DB search
MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETLIQNVILHEH
HIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL
VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL
GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPE
FRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECIL
TEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS
AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEF
TTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFL
LDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW
CHDKCVRSEECSSGTWTQQICLPAIYKVFPSSAPLEGGTRLTICGWDFGFRRNNKFDLKK
TRVLLGNESCTLTLSESTMNILKCTVGPAMNKHFNMSIIISNGHGTTQYSTFSYVDPVIT
GISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF
AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVH
EAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPV
FKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDL
LKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISIALLLLLGFFLWLKKRKQ
IKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGS
CRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHF
NEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVL
SLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKF
VHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKF
TTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCW
HPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADDEVD
TRPASFWETS
NT seq
4173 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccccgctgtgcttgcacctggcatcctcgtgctcctgtttaccttggtgcag
aggagcaatggggagtgtaaagaggcactagcaaagtccgagatgaatgtgaatatgaag
tatcagcttcccaacttcaccgcggaaacactcatccagaatgtcattctacatgagcat
cacattttccttggtgccactaactacatttatgttttaaatgaggaagaccttcagaag
gttgctgagtacaagaccgggcctgtgttggaacacccagattgtttcccatgtcaggac
tgcagcagcaaagccaatttatcaggaggcgtttggaaagataacatcaacatggctcta
gttgtcgacacctactatgatgatcaactcattagctgtggcagcgtcaacagagggacc
tgccagcgacatgtctttccccacaatcatactgctgacatacagtcggaggttcactgc
atattctccccacagatagaagagcccagccagtgtcctgactgtgtggtgagcgccctg
ggagccaaagtcctttcatctgtaaaggaccggttcatcaacttctttgtaggtaatacc
ataaattcttcttatttcccagatcatccattgcattcaatatcagtgagaaggctaaag
gaaacgaaagatggttttatgtttttgacggaccagtcctacattgatgttttacctgag
ttcagagattcttaccccattaagtatgtccatgcctttgaaagcaacaattttatttac
ttcttgacggtccaaagggaaactctagatgctcagacttttcacacaagaataatcagg
ttctgttccataaactctggattgcattcctacatggaaatgcctctggagtgtattctt
acagaaaagagaaaaaagagatccacaaagaaggaagtgtttaatatccttcaggctgcg
tatgtcagcaagcctggggcccaacttgctagacaaataggagccagcctgaatgatgac
attctctttggggtgttcgcacaaagcaagccagattctgccgaaccaatggatcgatct
gccatgtgtgcattccctatcaaatatgtcaacgacttcttcaacaagatcgtcaacaaa
aacaatgtgagatgtctccagcatttttacggacccaatcatgagcactgttttaatagg
acacttctgagaaattcatcaggctgtgaagcgcgccgtgatgaatatcgaacagagttt
accacagctttgcagcgcgttgacttattcatgggtcaattcagcgaagtcctcttaaca
tctatatccaccttcattaaaggagacctcaccatagctaatcttgggacatcagagggt
cgcttcatgcaggttgtggtttctcgatcaggaccatcaacccctcatgtgaattttctc
ctggactcccatccggtgtctccagaagtgattgtggagcatccattaaaccagaatggc
tacacactggttgtcactgggaagaagatcacgaagatcccattgaatggcttgggctgc
agacatttccagtcctgcagtcagtgcctctctgccccaccctttgttcagtgtggctgg
tgccatgacaaatgtgtgcgatcggaggaatgctcgagcgggacatggactcaacagatc
tgtctgcctgcaatctacaaggttttcccaagtagtgcaccccttgaaggagggacaagg
ctgaccatatgtggctgggactttggatttcggaggaataataaatttgatttaaagaaa
actagagttctccttggaaatgagagctgcaccttgactttaagtgagagcacgatgaat
atattgaaatgcacagttggtcctgccatgaataagcatttcaatatgtccataattatt
tcaaatggccacgggacaacacaatacagtacattctcctatgtggatcctgtaataaca
ggtatttcgccgaaatatggtcctatggctggtggcactttacttactttaactggaaat
tacctaaacagtgggaattccagacacatttcaattggtggaaaaacatgtactttaaaa
agtgtgtcaaacagtattcttgaatgttataccccagcccaaaccatttcaactgagttt
gctgttaaattgaaaattgacttagccaaccgagagacaagcatcttcagttaccgggaa
gatcccattgtctacgaaattcatccaaccaaatcttttattagtggtgggagcacaata
acaggtgttgggaaaaacctgaattcagttagtgtcccgaggatggtcataaatgtgcat
gaagcaggaaggaactttactgtggcatgtcaacatcgctctaattcagagataatctgc
tgtaccactccttccctgcaacagctgaatctgcaactccccctgaaaaccaaagccttt
ttcatgttagatgggatcctttccaaatactttgatctcatttatgtacataatcctgtg
tttaagccttttgaaaagccagtgatgatctcaatgggcaatgaaaatgtactggaaatt
aagggaaatgatattgaccctgaagcagttaaaggtgaagtgttaaaagttggaaataag
agctgtgagaatatacacttacattctgaagccgttttatgcacggtccccaatgacctg
ctgaaattgaacagcgagctaaatatagagtggaagcaagcaatttcttcaaccgtcctt
ggaaaagtaatagttcaaccagatcagaatttcacaggattgattgctggtgttgtctca
atatcaatagcactgttattactacttgggtttttcctgtggctgaaaaagagaaagcaa
attaaagatctgggcagtgaattagttcgctatgatgcaagagtacacactcctcatttg
gataggcttgtaagtgcccgaagtgtaagcccaactacagaaatggtttcaaatgaatct
gtagactaccgagctacttttccagaagatcagtttcctaattcatctcagaacggttca
tgccgacaagtgcagtatcctctgacagacatgtcccccatcctaactagtggggactct
gatatatccagtccattactgcaaaatactgtccacattgacctcagtgccctaaatcca
gagctggtccaggcagtgcaacatgtagtgattgggcccagtagcctgattgtgcatttc
aatgaagtcataggaagagggcattttggttgtgtatatcatgggactttgttggacaat
gatggcaagaaaattcactgtgctgtgaaatccttgaatagaatcactgacataggagaa
gtttcccaatttctgaccgagggaatcatcatgaaagattttagtcatcccaatgtcctc
tcgctcctgggaatctgcctgcgaagtgaagggtctccactggtggtcctaccatacatg
aaacatggagatcttcgaaatttcattcgaaatgagactcataatccaactgtaaaagat
cttattggctttggtcttcaagtagccaaaggcatgaaatatcttgcaagcaaaaagttt
gtccacagagacttggctgcaagaaactgtatgctggatgaaaaattcacagtcaaggtt
gctgattttggtcttgccagagacatgtatgataaagaatactatagtgtacacaacaaa
acaggtgcaaagctgccagtgaagtggatggctttggaaagtctgcaaactcaaaagttt
accaccaagtcagatgtgtggtcctttggcgtgctcctctgggagctgatgacaagagga
gccccaccttatcctgacgtgaacacctttgatataactgtttacttgttgcaagggaga
aggctcctacaacccgaatactgcccagaccccttatatgaagtaatgctaaaatgctgg
caccctaaagccgaaatgcgcccatccttttctgaactggtgtcccggatatcagcgatc
ttctctactttcattggggagcactatgtccatgtgaacgctacttatgtgaacgtaaaa
tgtgtcgctccatatccttctctgttgtcatcagaagataacgctgatgatgaggtggac
acacgaccagcctccttctgggagacatcatag
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integrated database retrieval system
