Pongo abelii (Sumatran orangutan): 100171460
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Entry
100171460 CDS
T01416
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00260
Glycine, serine and threonine metabolism
pon00630
Glyoxylate and dicarboxylate metabolism
pon00670
One carbon pool by folate
pon01100
Metabolic pathways
pon01200
Carbon metabolism
pon01230
Biosynthesis of amino acids
pon01240
Biosynthesis of cofactors
pon01523
Antifolate resistance
pon04981
Folate transport and metabolism
Module
pon_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100171460 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100171460 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100171460 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100171460 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100171460 (SHMT1)
Enzymes [BR:
pon01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100171460 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
100171460
NCBI-ProteinID:
NP_001124622
Ensembl:
ENSPPYG00000008051
UniProt:
Q5RFK5
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All DBs
Position
19:17909034..17943461
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AA seq
483 aa
AA seq
DB search
MTMPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELFASENFASQA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTGKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVQSVDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
VAHFIHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQGAVQALREKVESFASLFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atgacgatgccagtcaacggggcccacaaggatgctgacctgtggtcctcacatgacaag
atgctggcacaacccctcaaagacagtgatgttgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggattggagctgtttgcctcggagaatttcgccagccaagca
gttttggaggccctaggctcttgcttaaataacaaatactctgaggggtacccgggccag
agatactatggcgggactgagtttattgatgaactggagaccctctgtcagaagcgagcc
ctgcaggcctataagctggacccacagtgctggggggtcaacgtccagccctactcaggc
tcccctgcaaacttcgctgtgtacactgccctggtggaaccccatgggcgcatcatgggc
ctggacctgccggatgggggccacctgacccatgggttcatgacaggcaagaagaaaatc
tctgccacatccatcttctttgaatctatgccctataaggtgaacccagacactggctac
atcaactatgaccagctggaggagaatgcacgcctcttccacccgaagctgatcatcgca
ggaaccagctgctactcccgaaacctggactatgcccggctgcggaagattgcagatgag
aacggggcgtatctcatggcggacatggctcacatcagcgggctggtggcggctggtgtg
gtgccctccccatttgaacactgccacgtggtgaccaccaccactcacaagaccctgcga
ggctgccgagctggcatgatcttctaccggaaaggagtgcaaagtgtggatcccaagact
ggcaaagagattctgtacaacctggagtctctcatcaattctgctgtgttccctggcctg
cagggaggtccccacaaccacgccattgcgggggttgctgtggcactgaagcaagctatg
actctggaatttaaagtttatcaacaccaggtggtggccaactgcagggctctgtctgag
gcactgacggagctgggctacaaaatagtcacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagatggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgtccaggtgacagaagcgctctgcggcccagtgga
ctgcggctggggaccccagcactgacgtcccgtggacttttggaaaaagacttccaaaaa
gtagcccactttattcacagagggatagagctgaccctgcagatccagagcgacactggt
gtcagagccaccctgaaggagttcaaggagagactggcaggggataagtaccagggggcc
gtgcaggctctccgggagaaggttgagagcttcgcctctctcttccctctgcctggcctg
cctgacttctaa
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