Pongo abelii (Sumatran orangutan): 100171540
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Entry
100171540 CDS
T01416
Symbol
FGFR2
Name
(RefSeq) fibroblast growth factor receptor 2
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04144
Endocytosis
pon04151
PI3K-Akt signaling pathway
pon04550
Signaling pathways regulating pluripotency of stem cells
pon04810
Regulation of actin cytoskeleton
pon05200
Pathways in cancer
pon05215
Prostate cancer
pon05226
Gastric cancer
pon05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100171540 (FGFR2)
04014 Ras signaling pathway
100171540 (FGFR2)
04015 Rap1 signaling pathway
100171540 (FGFR2)
04020 Calcium signaling pathway
100171540 (FGFR2)
04151 PI3K-Akt signaling pathway
100171540 (FGFR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100171540 (FGFR2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100171540 (FGFR2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100171540 (FGFR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100171540 (FGFR2)
05230 Central carbon metabolism in cancer
100171540 (FGFR2)
09162 Cancer: specific types
05226 Gastric cancer
100171540 (FGFR2)
05215 Prostate cancer
100171540 (FGFR2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100171540 (FGFR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100171540 (FGFR2)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pon04090
]
100171540 (FGFR2)
00536 Glycosaminoglycan binding proteins [BR:
pon00536
]
100171540 (FGFR2)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100171540 (FGFR2)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
100171540 (FGFR2)
CD molecules [BR:
pon04090
]
Proteins
100171540 (FGFR2)
Glycosaminoglycan binding proteins [BR:
pon00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100171540 (FGFR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
Ig_2
ig
V-set
Ig_5
ABC1
C2-set_2
V-set_CD47
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
100171540
NCBI-ProteinID:
NP_001124693
Ensembl:
ENSPPYG00000002710
UniProt:
A0A8I5U6M7
Q5RF81
LinkDB
All DBs
Position
8:complement(128552204..128671688)
Genome browser
AA seq
840 aa
AA seq
DB search
MGLTSTWRYGRGPGIGTITMVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTK
YQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRD
SGLYACTATRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEK
MEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESV
VPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY
SDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMK
NTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLA
GVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRP
PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK
IADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG
SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIL
TLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
NT seq
2523 nt
NT seq
+upstream
nt +downstream
nt
atgggattaacgtccacatggagatatggaagaggaccagggattggtaccataaccatg
gtcagctggggtcgtttcatctgcctggtcgtggtcaccatggcaaccttgtccctggcc
cggccctccttcagtttagttgaggataccacattagagccagaagagccaccaaccaaa
taccaaatctctcaaccagaagtgtacgtggctgcgccaggggagtcgctagaggtgcgc
tgcctgttgaaagatgccgccgtgatcagttggactaaggatggggtgcacttggggccc
aacaataggacagtgcttattggggagtacttgcagataaagggcgccacgcctagagac
tccggcctctatgcttgtactgccactaggactgtagacagtgaaacttggtacttcatg
gtgaatgtcacagatgccatctcatctggagatgatgaggatgacaccgatggtgcggaa
gattttgtcagtgagaacagtaacaacaagagagcaccatactggaccaacacagaaaag
atggaaaagcggctccatgctgtgcctgcagccaacactgtcaagtttcgctgcccagcc
ggggggaacccaacaccgaccatgcggtggctgaaaaacgggaaggagtttaagcaggag
catcgcattggaggctacaaggtacgaaaccagcactggagcctcattatggaaagcgtg
gtcccatctgacaagggaaattatacctgtgtggtggagaatgaatacgggtccatcaat
cacacgtaccacctggatgttgtggagcgatcgcctcaccggcccatccttcaagccgga
ctgccggcaaatgcctccacagtggtcggaggagacgtagagtttgtctgcaaggtttac
agtgatgcccagccccacatccagtggatcaagcacgtggaaaagaacggcagtaaatac
gggcctgacgggctgccctacctcaaggttctcaaggccgccggtgttaacaccacggac
aaagagattgaggttctctatattcggaatgtaacttttgaggacgctggggaatatacg
tgcttggcgggtaattctattgggatatcctttcactctgcatggttgacagttctgcca
gctcctggaagagaaaaggagatcacagcttccccagactacctggagatagccatttac
tgcataggggtcttcttaatcgcctgtatggtggtaacagtcatcctgtgccgaatgaag
aacacgaccaagaagccagacttcagcagccagccggctgtgcacaagctgaccaagcgc
atccccctgcggagacaggtaacagtttcggctgagtccagctcctccatgaactccaat
accccgctggtgaggataacaacacgcctctcttcaacggcagacacccccatgctggca
ggggtctccgagtatgaacttccagaggacccaaaatgggagtttccaagagataagctg
acactgggcaagcccctgggagaaggttgctttgggcaagtggtcatggcggaagcagtg
ggaattgacaaagacaagcccaaggaggcggtcaccgtggccgtgaagatgttgaaagat
gatgccacagagaaagacctttctgatctggtgtcagagatggagatgatgaagatgatt
gggaaacacaagaatatcataaatcttcttggagcctgcacacaggatgggcctctctat
gtcatagttgagtatgcctctaaaggcaacctccgagaatacctccgagcccggaggcca
cccgggatggagtactcctatgacattaaccgtgttcctgaggagcagatgaccttcaag
gacttggtgtcatgcacctaccagctggccagaggcatggaatacttggcttcccaaaaa
tgtattcatcgagatttagcagccagaaatgttttggtaacagaaaacaatgtgatgaaa
atagcagactttggacttgccagagatatcaacaatatagactattacaaaaagaccacc
aatgggcgacttccagtcaagtggatggctccagaagccctgtttgatagagtatacact
catcagagtgatgtctggtccttcggggtgttaatgtgggagatcttcactttagggggc
tcgccctacccagggattcccgtggaggaactttttaagctgctgaaggaaggacacaga
atggataaaccagccaactgcaccaacgaactgtacatgatgatgagggactgttggcat
gcagtgccctcccagagaccaacgttcaagcagttggtagaagacttggatcgaattctc
actctcacaaccaatgaggaatacttggacctcagccaacctctcgaacagtattcacct
agttaccctgacacaagaagttcttgttcttcaggagatgattctgttttttctccagac
cccatgccttacgaaccatgccttcctcagtatccacacataaacggcagtgttaaaaca
tga
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