Pongo abelii (Sumatran orangutan): 100171634
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Entry
100171634 CDS
T01416
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00020
Citrate cycle (TCA cycle)
pon00480
Glutathione metabolism
pon01100
Metabolic pathways
pon01200
Carbon metabolism
pon01210
2-Oxocarboxylic acid metabolism
pon01230
Biosynthesis of amino acids
pon04146
Peroxisome
pon05230
Central carbon metabolism in cancer
Module
pon_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pon_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100171634 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
100171634 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
100171634 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100171634 (IDH1)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
100171634 (IDH1)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
100171634
NCBI-ProteinID:
NP_001124781
Ensembl:
ENSPPYG00000013125
UniProt:
Q5R9C5
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Position
11:complement(111585848..111604246)
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AA seq
414 aa
AA seq
DB search
MSKKISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDTFQEIYDKQYKSQFE
ARKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIVSIFAWTRGLAHRAKLDNNKELAFFANALE
EVSVETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLAQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatcagtggcggttctgtggtagagatgcaaggagatgaaatgacacga
atcatttgggaactgattaaagagaaactcatttttccctacgtggaattggatctacat
agctatgatttaggcatagagaatcgtgatgccaccaacgaccaagtcaccaaggatgct
gcagaagctataaagaagtataatgttggcgtcaaatgtgccactatcactcctgatgag
aagagggttgaggagttcaagttgaaacaaatgtggaaatcaccaaatggtaccatacga
aatattctgggtggcacagtcttcagagaagccattatctgcaaaaatatcccccggctt
gtgagtgggtgggtaaaacctatcatcataggtcgtcatgcttatggggatcaatacaga
gcaactgattttgttgttcctgggcctggaaaagtagagataacctacacaccaagtgac
gggacccaaaaggtgacatacctggtacataactttgaagagggtggtggtgttgccatg
gggatgtataatcaagataagtcaattgaagattttgcacacagttccttccaaatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
gggcgttttaaagacacctttcaggaaatatatgacaagcagtacaagtcccaatttgaa
gcacgaaagatctggtatgagcataggctcatcgacgacatggtggcccaagctatgaaa
tcagagggaggcttcatctgggcctgtaaaaactatgatggtgacgtgcagtcagactct
gtggcccaagggtatggctctctcggcatgatgaccagcgtgctggtttgtccagatggc
aagacagtagaagcagaggctgcccacgggactgtaacccgtcactaccgcatgtaccag
aaaggacaggagacgtccaccaatcccattgtttccatttttgcctggaccagagggtta
gcccacagagcaaagcttgataacaataaagagcttgccttctttgcaaatgctttggaa
gaagtctctgttgagacaattgaggctggcttcatgaccaaggacttggctgcttgcatt
aaaggtttacccaatgtgcaacgttctgactacttgaatacatttgagttcatggataaa
cttggagaaaacttgaagatcaaactagcccaggccaaactttaa
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