Pongo abelii (Sumatran orangutan): 100172452
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Entry
100172452 CDS
T01416
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00020
Citrate cycle (TCA cycle)
pon00620
Pyruvate metabolism
pon01100
Metabolic pathways
pon01200
Carbon metabolism
pon04934
Cushing syndrome
pon05200
Pathways in cancer
pon05211
Renal cell carcinoma
Module
pon_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pon_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100172452 (FH)
00620 Pyruvate metabolism
100172452 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100172452 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
100172452 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100172452 (FH)
Enzymes [BR:
pon01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
100172452 (FH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
100172452
NCBI-ProteinID:
NP_001125540
Ensembl:
ENSPPYG00000000071
UniProt:
Q5RBC0
LinkDB
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Position
1:7549464..7571941
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AA seq
510 aa
AA seq
DB search
MYRALRLLARSRRLVRAPASALASAPGLGGAAVPSFWPPNAARMASQNSFRIEYDTFGEL
KVPNDKYYGAQTVRSTMNFKIGGVTERMPTPVIKAFGILKRAAAEVNQDYGLDPKIANAI
MKAADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKIPVHPNDH
VNKSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKPKEFEQIIKIGRTHTQDAV
PLTLGQEFSGYVQQVKYAMTRTKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAAL
TGLPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPE
NEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSA
RLLGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGS
TLKETAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1533 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgagcacttcggctcctcgcgcgctcgcgtcgtctcgtgcgggctccagcctca
gccttagcttcggctcctggcttgggtggcgcggctgtgccctcgttttggcccccgaac
gcggctcgaatggcaagccaaaattccttccggatagaatatgatacctttggtgaacta
aaggtgccaaatgataagtattatggcgcccagacggtgagatctacgatgaactttaag
attggaggtgtgacagaacgcatgccaaccccagttattaaagcttttggcatcttgaag
cgagcagccgctgaagtaaaccaggattatggtcttgatccaaagattgctaatgcaata
atgaaggcagcagatgaggtagctgaaggtaaattaaatgatcattttcctcttgtggta
tggcagactggatcaggaactcagacaaatatgaatgtaaatgaagtcattagcaataga
gcaattgaaatgttaggaggtgaacttggcagcaagatacctgtgcatcccaatgatcat
gttaataaaagccagagctcaaatgatacttttcccacagcaatgcacattgctgctgca
atagaagttcatgaagtactgttaccaggactacagaagttacatgatgctcttgatgca
aaacccaaagagtttgagcagatcatcaagattggacgtactcatactcaggatgctgtt
ccacttactcttgggcaggaatttagtggttatgttcaacaagtaaaatatgcaatgaca
agaacaaaagctgccatgccaagaatctatgagctcgcagctggaggcactgctgttggt
acaggtttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactt
acaggcttgccttttgtcactgctccaaataaatttgaagctctggctgctcatgacgct
ctggttgagctcagtggagccatgaacactactgcctgcagtctgatgaagatagcaaat
gatattcgatttttgggttctggtcctcggtcaggtctcggagaattgatcttgcctgaa
aatgaaccaggaagcagtatcatgccaggcaaggtgaaccctactcaatgtgaagcaatg
accatggttgcagcccaagtcatggggaaccatgttgctgtcactgttggaggcagcaat
ggacattttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagcc
aggctgctgggggatgcttcagtttcctttacagaaaactgcgtggtgggaatccaggcc
aatacagaaaggatcaacaagctgatgaatgagtctctaatgttggtgacagctctcaat
cctcatatagggtatgacaaggcagcaaagattgctaagacagcacacaaaaatggatca
accttaaaggaaactgctattgaacttggctatctcacagcagagcagtttgacgaatgg
gtaaaacctaaggacatgctgggtccaaagtga
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