KEGG   Pongo abelii (Sumatran orangutan): 100173372
Entry
100173372         CDS       T01416                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04066  HIF-1 signaling pathway
pon04120  Ubiquitin mediated proteolysis
pon05200  Pathways in cancer
pon05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:pon00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    100173372 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    100173372 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100173372 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    100173372 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:pon04121]
    100173372 (VHL)
Ubiquitin system [BR:pon04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul2 complex
    Target recognizing subunit
     100173372 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 100173372
NCBI-ProteinID: NP_001126390
Ensembl: ENSPPYG00000034342
UniProt: Q5R798
LinkDB
Position
2:complement(68602615..68612652)
AA seq 213 aa
MRRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPR
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVQKDLERLTQEHIAHQRMGD
NT seq 642 nt   +upstreamnt  +downstreamnt
atgcgccggagggcggagaactgggacgaagccgaggtaggcgcggaggaggcaggcgtc
gaagagtacggtcctgaagaagacggcggggaggagtcgggcgccgaggagtccggcccg
gaagagtccggcccggaggaactgggcgccgaggaggagatggaggccgggcggccgcgg
cccgtgctgcgctcggtgaactcgcgggagccctcccaggtcatcttctgcaaccgcagc
ccgcgcgtcgtgctgccagtatggctcaacttcgacggcgagccgcagccctacccaacg
ctgccgcctggcacgggccgccgcatccacagctaccgaggtcacctttggctcttcaga
gatgcagggacacacgatgggcttctcgttaaccaaactgaattatttgtgccatctctc
aatgttgacggacagcctatttttgccaatatcacactgccagtgtatactctgaaagag
cgatgcctccaggttgtccggagcctagtcaaacctgagaattacaggagactggacatc
gtcaggtcgctctacgaagatctggaagaccacccaaatgtgcagaaagacctggagcgg
ctgacgcaagagcacattgcacatcaacggatgggagattga

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