Pongo abelii (Sumatran orangutan): 100173944
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Entry
100173944 CDS
T01416
Symbol
HSPA5
Name
(RefSeq) endoplasmic reticulum chaperone BiP precursor
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon03060
Protein export
pon04141
Protein processing in endoplasmic reticulum
pon04612
Antigen processing and presentation
pon04918
Thyroid hormone synthesis
pon05012
Parkinson disease
pon05014
Amyotrophic lateral sclerosis
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
100173944 (HSPA5)
04141 Protein processing in endoplasmic reticulum
100173944 (HSPA5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
100173944 (HSPA5)
09152 Endocrine system
04918 Thyroid hormone synthesis
100173944 (HSPA5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100173944 (HSPA5)
05014 Amyotrophic lateral sclerosis
100173944 (HSPA5)
05020 Prion disease
100173944 (HSPA5)
05022 Pathways of neurodegeneration - multiple diseases
100173944 (HSPA5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100173944 (HSPA5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
pon03110
]
100173944 (HSPA5)
04131 Membrane trafficking [BR:
pon04131
]
100173944 (HSPA5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
pon04147
]
100173944 (HSPA5)
Enzymes [BR:
pon01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
100173944 (HSPA5)
Chaperones and folding catalysts [BR:
pon03110
]
Heat shock proteins
HSP70 / DNAK
100173944 (HSPA5)
Membrane trafficking [BR:
pon04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
100173944 (HSPA5)
Autophagy
ER-phagy
ER stress-related proteins
100173944 (HSPA5)
Exosome [BR:
pon04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100173944 (HSPA5)
Exosomal proteins of other body fluids (saliva and urine)
100173944 (HSPA5)
Exosomal proteins of colorectal cancer cells
100173944 (HSPA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Motif
Other DBs
NCBI-GeneID:
100173944
NCBI-ProteinID:
NP_001126927
Ensembl:
ENSPPYG00000019609
UniProt:
Q5R4P0
LinkDB
All DBs
Position
13:complement(116520144..116525241)
Genome browser
AA seq
654 aa
AA seq
DB search
MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPPYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLALLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagctctccctggtggccgcgatgctgctgctgctcagcgcggcgcgggccgaggag
gaggacaagaaggaggacgtgggtaccgtggtcggcatcgacctggggaccacctactcc
tgcgtcggcgtgttcaagaacggccgcgtggagatcatcgccaacgatcagggcaaccgc
atcacgccgccctatgtggccttcactcctgaaggggaacgtctgatcggcgatgccgcc
aagaaccagctcacctccaaccccgaaaacacggtctttgacgccaagcggctcatcggc
cgcacgtggaatgacccgtctgtgcagcaggacatcaagttcttgccgttcaaggtggtt
gaaaagaaaactaaaccatacattcaagttgacattggaggtgggcaaacaaagacattt
gctcctgaagaaatttctgccatggttctcactaaaatgaaagaaaccgctgaggcttat
ttgggaaagaaggttacccatgcagttgttactgtaccagcctattttaatgatgcccaa
cgccaagcaaccaaagacgctggaactattgctggcctaaatgttatgaggatcatcaac
gagcctacggcagctgctattgcttatggactggataagagggagggggagaagaacatc
ctggtgtttgacctgggtggcggaaccttcgatgtgtctcttctcaccattgacaatggt
gtcttcgaagtcgtggccactaatggagatactcatctgggtggagaagactttgaccag
cgtgtcatggaacacttcatcaaactgtacaaaaagaagactggcaaagatgtcaggaaa
gacaacagagctgtgcagaaactccggcgcgaggtagaaaaggccaaacgggccctgtct
tctcaacatcaagcaagaattgaaattgagtccttctatgaaggagaagacttttctgag
accctgactcgggccaaatttgaagagctcaacatggatctgttccggtctactatgaag
cccgtccagaaagtgttggaagattctgatttgaagaagtctgatattgatgaaattgtt
cttgttggtggctcgactcgaattccaaagattcagcaactggttaaagagttcttcaat
ggcaaggaaccatcccgcggcataaacccagatgaagctgtagcgtatggtgctgctgtc
caggctggtgtgctctctggtgatcaagatacaggtgacctggcactgcttgatgtatgt
ccccttacacttggtattgaaactgtgggaggtgtcatgaccaaactgattccaaggaac
acagtggtgcctaccaagaagtctcagatcttttctacagcttctgataatcaaccaact
gttacaatcaaggtctatgaaggtgaacgacccctgacaaaagacaatcatcttctgggt
acatttgatctgactggaattcctcctgctcctcgtggggtcccacagattgaagtcacc
tttgagatagatgtgaatggtattcttcgagtgacagctgaagacaagggtacagggaac
aaaaataagatcacgattaccaatgaccagaatcgcctgacacctgaagaaatcgaaagg
atggttaatgatgctgagaagtttgctgaggaagacaaaaagctcaaggagcgcattgat
actagaaatgagttggaaagctatgcatattctctaaagaatcagattggagataaagaa
aagctgggaggtaaactttcctctgaagataaggagaccatggaaaaagctgtagaagaa
aagattgaatggctggaaagccaccaagatgctgacattgaagacttcaaagctaagaag
aaggaactggaagaaattgttcaaccaattatcagcaaactctatggaagtgcaggccct
cccccaactggtgaagaggatacagcagaaaaagatgagttgtag
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