| Entry |
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| Symbol |
APP
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| Name |
(RefSeq) amyloid-beta precursor protein precursor
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| KO |
| K04520 | amyloid beta A4 protein |
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| Organism |
pon Pongo abelii (Sumatran orangutan)
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| Pathway |
| pon05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:pon00001]
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
100174038 (APP)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100174038 (APP)
05022 Pathways of neurodegeneration - multiple diseases
100174038 (APP)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:pon01002]
100174038 (APP)
09183 Protein families: signaling and cellular processes
00535 Proteoglycans [BR:pon00535]
100174038 (APP)
00536 Glycosaminoglycan binding proteins [BR:pon00536]
100174038 (APP)
Peptidases and inhibitors [BR:pon01002]
Peptidase inhibitors
Family I2: Kunitz - BPTI family
100174038 (APP)
Proteoglycans [BR:pon00535]
Cell surface proteoglycans
Others
100174038 (APP)
Glycosaminoglycan binding proteins [BR:pon00536]
Heparan sulfate / Heparin
Others
100174038 (APP)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22:complement(36038336..36320820)
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| AA seq |
695 aa
MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTK
TCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVG
EFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFR
GVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEE
EAHDDEDDEDGDEVEEEAEEPYGEATERTTSIATTTTTTTESVEEVVRVPTTAASTPDAV
DKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHF
QEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLK
KYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVA
EEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNEALMPSLTETKTTVELLPVNGEFSL
DDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEF
RHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGV
VEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN |
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| NT seq |
2088 nt +upstreamnt +downstreamnt
atgctgcccggtttggcactgctcctgctggccgcctggacggctcgggcgctggaggta
cccactgatggcaatgctggcctgctggctgaaccccagattgccatgttctgtggcaga
ctgaacatgcacatgaatgtccagaatgggaagtgggattcagatccatcagggaccaaa
acctgcattgataccaaggaaggcatcctgcagtattgccaagaagtctaccctgaactg
cagatcaccaatgtggtagaagccaaccaaccagtgaccatccagaactggtgcaagcgg
ggccgcaagcagtgcaagacccatccccactttgtgattccctaccgctgcttagttggt
gaatttgtaagcgatgcccttctcgttcctgacaagtgcaaattcttgcaccaggagagg
atggatgtttgtgaaactcatcttcactggcacaccgtcgccaaagagacgtgcagtgag
aagagtaccaacttgcatgactacggcatgttgctgccctgcggaattgacaagttccga
ggggtagagtttgtgtgttgcccactggctgaggaaagtgacaatgtggattctgctgac
gcggaggaggatgactcggatgtctggtggggcggagcagacacagactatgcagatggg
agtgaagacaaagtagtagaagtagcagaggaggaagaagtggctgaggtggaagaagaa
gaagctcatgatgacgaggatgatgaggatggtgacgaggtagaggaagaggctgaggaa
ccctacggagaagccacagagagaaccaccagcatcgccaccaccaccaccaccaccaca
gagtctgtggaagaggtggttcgagttcctacaacagcagccagtacccctgatgccgtt
gacaagtatctcgagacacctggggatgagaatgaacacgcccatttccagaaagccaaa
gagaggcttgaggccaagcaccgagagagaatgtcccaggtcatgagagaatgggaagag
gcagaacgtcaagcaaagaacttgcctaaagctgataagaaggcagttatccagcatttc
caggagaaagtggaatctttggaacaggaagcagccaacgagagacagcagctggtggag
acacacatggccagagtggaagccatgctcaatgaccgccgccgcctggccctggagaac
tacatcaccgctctgcaggctgttcctcctcggcctcgtcacgtgttcaatatgctaaag
aagtatgtccgcgcagaacagaaggacagacagcacaccctaaagcatttcgagcatgtg
cgcatggtggatcccaagaaagctgctcagatccggtcccaggttatgacacacctccgt
gtgatttacgagcgcatgaatcagtctctctccctgctctacaacgtgcctgcagtggcc
gaggagattcaggatgaagttgatgagctgcttcagaaagagcaaaactattcagatgac
gtcttggccaacatgattagtgaaccaaggatcagttacggaaacgaagccctcatgccg
tctttgaccgaaacgaaaaccaccgtggagcttcttcctgtgaatggagagttcagcctg
gacgatctccagccgtggcattcttttggggctgactctgtgccagccaacacagaaaac
gaagttgagcctgttgatgcccgtcctgctgccgaccggggactgaccactcgaccaggt
tctgggttgacaaatatcaagacggaggagatctctgaagtgaagatggatgcagaattc
cgacatgactcgggatatgaagttcatcatcaaaaattggtgttctttgcagaagatgtg
ggttcaaacaaaggtgcaatcattggactcatggtgggcggtgttgtcatagcgacagtg
atcgtcatcaccttggtgatgctgaagaagaaacagtacacatccattcatcatggtgtg
gtggaggttgacgccgctgtcaccccagaggagcgccacctgtccaagatgcagcagaac
ggctatgaaaatccaacctacaagttctttgagcagatgcagaactag |
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