Pongo abelii (Sumatran orangutan): 100174735
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Entry
100174735 CDS
T01416
Symbol
CHUK
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit alpha
KO
K04467
inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:
2.7.11.10
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01523
Antifolate resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04062
Chemokine signaling pathway
pon04064
NF-kappa B signaling pathway
pon04068
FoxO signaling pathway
pon04150
mTOR signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04210
Apoptosis
pon04380
Osteoclast differentiation
pon04620
Toll-like receptor signaling pathway
pon04621
NOD-like receptor signaling pathway
pon04622
RIG-I-like receptor signaling pathway
pon04623
Cytosolic DNA-sensing pathway
pon04625
C-type lectin receptor signaling pathway
pon04657
IL-17 signaling pathway
pon04658
Th1 and Th2 cell differentiation
pon04659
Th17 cell differentiation
pon04660
T cell receptor signaling pathway
pon04662
B cell receptor signaling pathway
pon04668
TNF signaling pathway
pon04920
Adipocytokine signaling pathway
pon04936
Alcoholic liver disease
pon05010
Alzheimer disease
pon05132
Salmonella infection
pon05135
Yersinia infection
pon05142
Chagas disease
pon05145
Toxoplasmosis
pon05160
Hepatitis C
pon05161
Hepatitis B
pon05162
Measles
pon05163
Human cytomegalovirus infection
pon05164
Influenza A
pon05165
Human papillomavirus infection
pon05166
Human T-cell leukemia virus 1 infection
pon05167
Kaposi sarcoma-associated herpesvirus infection
pon05168
Herpes simplex virus 1 infection
pon05169
Epstein-Barr virus infection
pon05170
Human immunodeficiency virus 1 infection
pon05171
Coronavirus disease - COVID-19
pon05200
Pathways in cancer
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05212
Pancreatic cancer
pon05215
Prostate cancer
pon05220
Chronic myeloid leukemia
pon05221
Acute myeloid leukemia
pon05222
Small cell lung cancer
pon05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05417
Lipid and atherosclerosis
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100174735 (CHUK)
04014 Ras signaling pathway
100174735 (CHUK)
04064 NF-kappa B signaling pathway
100174735 (CHUK)
04668 TNF signaling pathway
100174735 (CHUK)
04068 FoxO signaling pathway
100174735 (CHUK)
04151 PI3K-Akt signaling pathway
100174735 (CHUK)
04150 mTOR signaling pathway
100174735 (CHUK)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
100174735 (CHUK)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100174735 (CHUK)
04621 NOD-like receptor signaling pathway
100174735 (CHUK)
04622 RIG-I-like receptor signaling pathway
100174735 (CHUK)
04623 Cytosolic DNA-sensing pathway
100174735 (CHUK)
04625 C-type lectin receptor signaling pathway
100174735 (CHUK)
04660 T cell receptor signaling pathway
100174735 (CHUK)
04658 Th1 and Th2 cell differentiation
100174735 (CHUK)
04659 Th17 cell differentiation
100174735 (CHUK)
04657 IL-17 signaling pathway
100174735 (CHUK)
04662 B cell receptor signaling pathway
100174735 (CHUK)
04062 Chemokine signaling pathway
100174735 (CHUK)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100174735 (CHUK)
09158 Development and regeneration
04380 Osteoclast differentiation
100174735 (CHUK)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100174735 (CHUK)
05208 Chemical carcinogenesis - reactive oxygen species
100174735 (CHUK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100174735 (CHUK)
09162 Cancer: specific types
05212 Pancreatic cancer
100174735 (CHUK)
05221 Acute myeloid leukemia
100174735 (CHUK)
05220 Chronic myeloid leukemia
100174735 (CHUK)
05215 Prostate cancer
100174735 (CHUK)
05222 Small cell lung cancer
100174735 (CHUK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100174735 (CHUK)
05170 Human immunodeficiency virus 1 infection
100174735 (CHUK)
05161 Hepatitis B
100174735 (CHUK)
05160 Hepatitis C
100174735 (CHUK)
05171 Coronavirus disease - COVID-19
100174735 (CHUK)
05164 Influenza A
100174735 (CHUK)
05162 Measles
100174735 (CHUK)
05168 Herpes simplex virus 1 infection
100174735 (CHUK)
05163 Human cytomegalovirus infection
100174735 (CHUK)
05167 Kaposi sarcoma-associated herpesvirus infection
100174735 (CHUK)
05169 Epstein-Barr virus infection
100174735 (CHUK)
05165 Human papillomavirus infection
100174735 (CHUK)
09171 Infectious disease: bacterial
05132 Salmonella infection
100174735 (CHUK)
05135 Yersinia infection
100174735 (CHUK)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100174735 (CHUK)
05142 Chagas disease
100174735 (CHUK)
09164 Neurodegenerative disease
05010 Alzheimer disease
100174735 (CHUK)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100174735 (CHUK)
05418 Fluid shear stress and atherosclerosis
100174735 (CHUK)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100174735 (CHUK)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100174735 (CHUK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100174735 (CHUK)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100174735 (CHUK)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: Other
IKK family [OT]
100174735 (CHUK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Kdo
TBK1_ULD
YrbL-PhoP_reg
Motif
Other DBs
NCBI-GeneID:
100174735
NCBI-ProteinID:
NP_001127653
Ensembl:
ENSPPYG00000002562
UniProt:
Q5R4K1
LinkDB
All DBs
Position
8:complement(107124556..107165345)
Genome browser
AA seq
457 aa
AA seq
DB search
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMSGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLNWDPQQRGGPVDLTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGI
SLDPRKPASQCVLDGVVRKLIIISLEYVKSRGIACPAIFMHTWNSLGGRTFCFGFVLLPT
LIIALQGEQDRNETFVVLNFARLFLWCQFSAPVPRPN
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
ctgggcaccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaa
atagcaattaagtcttgtcgcctagagctaagtaccaaaaacagagaacgatggtgccat
gaaatccagattatgaagaagttgaaccatgccaatgttgtaaaggcctgtgatgttcct
gaagaactgaatattttgattcatgatgtgcctcttctagcaatggaatactgttctgga
ggagatctccgaaagctgctcaacaaaccagaaaattgttgtggacttaaagaaagccag
atactttctttactaagtgatatagggtctgggattcgatatttgcatgaaaacaaaatt
atacatcgagatctaaaacctgaaaacatagttcttcaggatgttggtggaaagataata
cataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatct
tttgtgggaacactgcagtatctggccccagagctctttgagaataagccttacacagcc
actgttgattattggagctttgggaccatggtatttgaatgtattgctggatataggcct
tttttgcatcatctgcaaccatttacctggcatgagaagattaagaagaaggatccaaag
tgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctacagttgatgttg
aattgggacccacagcagagaggaggacctgttgaccttactttgaagcagccaagatgt
tttgtattaatggatcacattttgaatttgaagatagtacacatcctaaatatgacttct
gcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgt
attgagcgtgaaactggaataaatactggttctcaagaacttctttcggagacaggaatt
tctctggatcctcggaaaccagcctctcaatgtgttctagatggagttgtaagaaaatta
attataatatccctagagtatgtgaaatctagagggattgcatgtcctgcaatttttatg
catacttggaattccttgggaggccgcacattttgttttggttttgtcctactcccaact
cttatcattgctttgcaaggtgaacaggatagaaatgaaacatttgttgttttaaacttt
gcaagactttttctttggtgccagttttctgctcctgttcccagaccaaactga
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