Pongo abelii (Sumatran orangutan): 100174748
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Entry
100174748 CDS
T01416
Symbol
PRKACB
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit beta isoform 2
KO
K04345
protein kinase A [EC:
2.7.11.11
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01522
Endocrine resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04020
Calcium signaling pathway
pon04024
cAMP signaling pathway
pon04062
Chemokine signaling pathway
pon04081
Hormone signaling
pon04082
Neuroactive ligand signaling
pon04114
Oocyte meiosis
pon04140
Autophagy - animal
pon04211
Longevity regulating pathway
pon04213
Longevity regulating pathway - multiple species
pon04261
Adrenergic signaling in cardiomyocytes
pon04270
Vascular smooth muscle contraction
pon04310
Wnt signaling pathway
pon04340
Hedgehog signaling pathway
pon04371
Apelin signaling pathway
pon04530
Tight junction
pon04540
Gap junction
pon04611
Platelet activation
pon04713
Circadian entrainment
pon04714
Thermogenesis
pon04720
Long-term potentiation
pon04723
Retrograde endocannabinoid signaling
pon04724
Glutamatergic synapse
pon04725
Cholinergic synapse
pon04726
Serotonergic synapse
pon04727
GABAergic synapse
pon04728
Dopaminergic synapse
pon04740
Olfactory transduction
pon04742
Taste transduction
pon04750
Inflammatory mediator regulation of TRP channels
pon04910
Insulin signaling pathway
pon04911
Insulin secretion
pon04912
GnRH signaling pathway
pon04913
Ovarian steroidogenesis
pon04914
Progesterone-mediated oocyte maturation
pon04915
Estrogen signaling pathway
pon04916
Melanogenesis
pon04918
Thyroid hormone synthesis
pon04919
Thyroid hormone signaling pathway
pon04921
Oxytocin signaling pathway
pon04922
Glucagon signaling pathway
pon04923
Regulation of lipolysis in adipocytes
pon04924
Renin secretion
pon04925
Aldosterone synthesis and secretion
pon04926
Relaxin signaling pathway
pon04927
Cortisol synthesis and secretion
pon04928
Parathyroid hormone synthesis, secretion and action
pon04934
Cushing syndrome
pon04935
Growth hormone synthesis, secretion and action
pon04961
Endocrine and other factor-regulated calcium reabsorption
pon04962
Vasopressin-regulated water reabsorption
pon04970
Salivary secretion
pon04971
Gastric acid secretion
pon04976
Bile secretion
pon05012
Parkinson disease
pon05020
Prion disease
pon05030
Cocaine addiction
pon05031
Amphetamine addiction
pon05032
Morphine addiction
pon05034
Alcoholism
pon05146
Amoebiasis
pon05163
Human cytomegalovirus infection
pon05165
Human papillomavirus infection
pon05166
Human T-cell leukemia virus 1 infection
pon05200
Pathways in cancer
pon05203
Viral carcinogenesis
pon05205
Proteoglycans in cancer
pon05207
Chemical carcinogenesis - receptor activation
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100174748 (PRKACB)
04014 Ras signaling pathway
100174748 (PRKACB)
04310 Wnt signaling pathway
100174748 (PRKACB)
04340 Hedgehog signaling pathway
100174748 (PRKACB)
04371 Apelin signaling pathway
100174748 (PRKACB)
04020 Calcium signaling pathway
100174748 (PRKACB)
04024 cAMP signaling pathway
100174748 (PRKACB)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
100174748 (PRKACB)
04081 Hormone signaling
100174748 (PRKACB)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100174748 (PRKACB)
09143 Cell growth and death
04114 Oocyte meiosis
100174748 (PRKACB)
09144 Cellular community - eukaryotes
04530 Tight junction
100174748 (PRKACB)
04540 Gap junction
100174748 (PRKACB)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100174748 (PRKACB)
04062 Chemokine signaling pathway
100174748 (PRKACB)
09152 Endocrine system
04911 Insulin secretion
100174748 (PRKACB)
04910 Insulin signaling pathway
100174748 (PRKACB)
04922 Glucagon signaling pathway
100174748 (PRKACB)
04923 Regulation of lipolysis in adipocytes
100174748 (PRKACB)
04912 GnRH signaling pathway
100174748 (PRKACB)
04913 Ovarian steroidogenesis
100174748 (PRKACB)
04915 Estrogen signaling pathway
100174748 (PRKACB)
04914 Progesterone-mediated oocyte maturation
100174748 (PRKACB)
04921 Oxytocin signaling pathway
100174748 (PRKACB)
04926 Relaxin signaling pathway
100174748 (PRKACB)
04935 Growth hormone synthesis, secretion and action
100174748 (PRKACB)
04918 Thyroid hormone synthesis
100174748 (PRKACB)
04919 Thyroid hormone signaling pathway
100174748 (PRKACB)
04928 Parathyroid hormone synthesis, secretion and action
100174748 (PRKACB)
04916 Melanogenesis
100174748 (PRKACB)
04924 Renin secretion
100174748 (PRKACB)
04925 Aldosterone synthesis and secretion
100174748 (PRKACB)
04927 Cortisol synthesis and secretion
100174748 (PRKACB)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100174748 (PRKACB)
04270 Vascular smooth muscle contraction
100174748 (PRKACB)
09154 Digestive system
04970 Salivary secretion
100174748 (PRKACB)
04971 Gastric acid secretion
100174748 (PRKACB)
04976 Bile secretion
100174748 (PRKACB)
09155 Excretory system
04962 Vasopressin-regulated water reabsorption
100174748 (PRKACB)
04961 Endocrine and other factor-regulated calcium reabsorption
100174748 (PRKACB)
09156 Nervous system
04724 Glutamatergic synapse
100174748 (PRKACB)
04727 GABAergic synapse
100174748 (PRKACB)
04725 Cholinergic synapse
100174748 (PRKACB)
04728 Dopaminergic synapse
100174748 (PRKACB)
04726 Serotonergic synapse
100174748 (PRKACB)
04720 Long-term potentiation
100174748 (PRKACB)
04723 Retrograde endocannabinoid signaling
100174748 (PRKACB)
09157 Sensory system
04740 Olfactory transduction
100174748 (PRKACB)
04742 Taste transduction
100174748 (PRKACB)
04750 Inflammatory mediator regulation of TRP channels
100174748 (PRKACB)
09149 Aging
04211 Longevity regulating pathway
100174748 (PRKACB)
04213 Longevity regulating pathway - multiple species
100174748 (PRKACB)
09159 Environmental adaptation
04713 Circadian entrainment
100174748 (PRKACB)
04714 Thermogenesis
100174748 (PRKACB)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100174748 (PRKACB)
05205 Proteoglycans in cancer
100174748 (PRKACB)
05207 Chemical carcinogenesis - receptor activation
100174748 (PRKACB)
05203 Viral carcinogenesis
100174748 (PRKACB)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100174748 (PRKACB)
05163 Human cytomegalovirus infection
100174748 (PRKACB)
05165 Human papillomavirus infection
100174748 (PRKACB)
09174 Infectious disease: parasitic
05146 Amoebiasis
100174748 (PRKACB)
09164 Neurodegenerative disease
05012 Parkinson disease
100174748 (PRKACB)
05020 Prion disease
100174748 (PRKACB)
09165 Substance dependence
05030 Cocaine addiction
100174748 (PRKACB)
05031 Amphetamine addiction
100174748 (PRKACB)
05032 Morphine addiction
100174748 (PRKACB)
05034 Alcoholism
100174748 (PRKACB)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
100174748 (PRKACB)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100174748 (PRKACB)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
100174748 (PRKACB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100174748 (PRKACB)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
pon03019
]
100174748 (PRKACB)
03036 Chromosome and associated proteins [BR:
pon03036
]
100174748 (PRKACB)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.11 cAMP-dependent protein kinase
100174748 (PRKACB)
Protein kinases [BR:
pon01001
]
Serine/threonine kinases: AGC group
PKA family
100174748 (PRKACB)
Messenger RNA biogenesis [BR:
pon03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
100174748 (PRKACB)
Chromosome and associated proteins [BR:
pon03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100174748 (PRKACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Pkinase_C
OST_P1
Motif
Other DBs
NCBI-GeneID:
100174748
NCBI-ProteinID:
NP_001127665
Ensembl:
ENSPPYG00000001209
UniProt:
Q5R472
LinkDB
All DBs
Position
1:complement(148759017..148915987)
Genome browser
AA seq
354 aa
AA seq
DB search
MSARKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGR
VMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNL
YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDH
QGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP
PFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW
FATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
NT seq
1065 nt
NT seq
+upstream
nt +downstream
nt
atgagtgcacgcaaatcatcagatgcatctgcttgctcctcttcagaaatatctgtgaaa
gagtttctagccaaagccaaagaagactttttgaaaaaatgggagaatccaactcagaat
aatgccggacttgaagattttgaaaggaaaaaaacccttggaacaggttcatttggaaga
gtcatgttggtaaaacacaaagccactgaacagtattatgccatgaagatcttagataag
cagaaggttgttaaactgaagcaaatagagcatactttgaatgagaaaagaatattacag
gcagtgaattttcctttccttgttcgactggagtatgcttttaaggataattctaattta
tacatggttatggaatatgtccctgggggtgaaatgttttcacatctaagacgaattgga
aggttcagtgagccccatgcaaggttctatgcagctcagatagtgctaacattcgagtac
ctccattcactagacctcatctacagagatctaaaacctgaaaatctcttaattgaccat
caaggctatatccaggtcacagactttgggtttgccaaaagagttaaaggcagaacttgg
acattatgtggaactccagagtatttggctccagaaataattctcagcaagggctacaat
aaggcagtggattggtgggcattaggagtgctaatctatgaaatggcagctggctatccc
ccattctttgcagaccaaccaattcagatttatgaaaagattgtttctggaaaggtccga
ttcccatcccacttcagttcagatctcaaggaccttctacggaacctgctgcaggtggat
ttgaccaagagatttggaaatctaaagaatggtgtcagtgatataaaaactcacaagtgg
tttgccacgacagattggattgctatttaccagaggaaggttgaagctccattcatacca
aagtttagaggctctggagataccagcaactttgatgactatgaagaagaagatatccgt
gtctctataacagaaaaatgtgcaaaagaatttggtgaattttaa
DBGET
integrated database retrieval system