| Entry |
|
|---|
| Symbol |
TBK1
|
|---|
| Name |
(RefSeq) serine/threonine-protein kinase TBK1 isoform X2
|
|---|
| KO |
|
|---|
| Organism |
pon Pongo abelii (Sumatran orangutan)
|
|---|
| Pathway |
| pon04620 | Toll-like receptor signaling pathway |
| pon04621 | NOD-like receptor signaling pathway |
| pon04622 | RIG-I-like receptor signaling pathway |
| pon05022 | Pathways of neurodegeneration - multiple diseases |
| pon05163 | Human cytomegalovirus infection |
| pon05167 | Kaposi sarcoma-associated herpesvirus infection |
| pon05168 | Herpes simplex virus 1 infection |
| pon05170 | Human immunodeficiency virus 1 infection |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:pon00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100433568 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100433568 (TBK1)
04137 Mitophagy - animal
100433568 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100433568 (TBK1)
04621 NOD-like receptor signaling pathway
100433568 (TBK1)
04622 RIG-I-like receptor signaling pathway
100433568 (TBK1)
04623 Cytosolic DNA-sensing pathway
100433568 (TBK1)
04657 IL-17 signaling pathway
100433568 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100433568 (TBK1)
05161 Hepatitis B
100433568 (TBK1)
05160 Hepatitis C
100433568 (TBK1)
05171 Coronavirus disease - COVID-19
100433568 (TBK1)
05164 Influenza A
100433568 (TBK1)
05162 Measles
100433568 (TBK1)
05168 Herpes simplex virus 1 infection
100433568 (TBK1)
05163 Human cytomegalovirus infection
100433568 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100433568 (TBK1)
05169 Epstein-Barr virus infection
100433568 (TBK1)
05165 Human papillomavirus infection
100433568 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100433568 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100433568 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
100433568 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100433568 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100433568 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:pon01001]
100433568 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:pon04131]
100433568 (TBK1)
Enzymes [BR:pon01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
100433568 (TBK1)
Protein kinases [BR:pon01001]
Serine/threonine kinases: Other
IKK family [OT]
100433568 (TBK1)
Membrane trafficking [BR:pon04131]
Autophagy
Xenophagy
Other xenophagy associated proteins
100433568 (TBK1)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
10:62402650..62452827
|
|---|
| AA seq |
729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELIKDDYNETVHKKTEVVITLDFCVRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGSLADAWAHQE
GTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLNKSEEWIRKMLHLRKQLLSLTNQCFDIEEEVSKYQEYTNELQETLPQ
KMFTASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL |
|---|
| NT seq |
2190 nt +upstreamnt +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttgaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtgggagtttatacactgttttagaagaa
ccttctaatgcctatggactaccagaatctgaattcttaattgttttgcgagatgtggtg
ggtggaatgaatcatctacgagagaatggtatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
caccctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatatggagca
acagttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccctttgaagggcctcgtaggaataaagaagtgatgtataaaataattacagga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcctgtttcttgcagtctttctcggggtcttcaggttctacttacccctgtt
cttgcaaacatccttgaagcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatattcatagctataatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatctatgaagggcgacgcttagtc
ttagaacctggaagactggcacaacatttccctaaaactactgaggaaaaccctatattt
gtagtaagccgggaacctctgaataccataggattaatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagacggggatgctagcatggctaaggcaataacaggg
gttgtgtgttatgcctgcagaattgccagtaccttactgctttatcaggaattaatgcga
aaggggatacgatggctgattgaattaattaaagatgattacaatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgtgtcagaaacattgaaaaaactgtgaaa
gtatacgaaaagttgatgaagatcaacctagaagcggcagagttaggtgaaatttcagac
atacacacgaaattattgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgacagcagattgtctccaggtggatcgctggcagacgcatgggcacatcaagaa
ggcactcatccgaaagacagaaacgtagaaaaactacaagtcctgttaaattgcatgaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagattagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacacac
tttacagatgaatgtgttaaaaagtatgaggcatttttgaataagtcagaagaatggata
agaaagatgcttcatcttaggaaacagttattatctctgactaatcagtgttttgatatt
gaagaagaagtatcaaaatatcaagaatatactaatgagttacaagaaactctgcctcag
aaaatgtttacagcttccagtggaatcaaacataccatgaccccaatttatccaagttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagagatggaaggggtg
gttaaagaacttgctgaaaataaccacattttagaaaggtttggctctttaaccatggat
ggtggccttcgcaacgttgactgtctttag |
|---|
