Pongo abelii (Sumatran orangutan): 100433948
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Entry
100433948 CDS
T01416
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04020
Calcium signaling pathway
pon04022
cGMP-PKG signaling pathway
pon04024
cAMP signaling pathway
pon04260
Cardiac muscle contraction
pon04261
Adrenergic signaling in cardiomyocytes
pon04270
Vascular smooth muscle contraction
pon04723
Retrograde endocannabinoid signaling
pon04725
Cholinergic synapse
pon04726
Serotonergic synapse
pon04727
GABAergic synapse
pon04911
Insulin secretion
pon04912
GnRH signaling pathway
pon04921
Oxytocin signaling pathway
pon04924
Renin secretion
pon04925
Aldosterone synthesis and secretion
pon04927
Cortisol synthesis and secretion
pon04929
GnRH secretion
pon04934
Cushing syndrome
pon04935
Growth hormone synthesis, secretion and action
pon05010
Alzheimer disease
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05207
Chemical carcinogenesis - receptor activation
pon05410
Hypertrophic cardiomyopathy
pon05412
Arrhythmogenic right ventricular cardiomyopathy
pon05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100433948 (CACNA1S)
04020 Calcium signaling pathway
100433948 (CACNA1S)
04024 cAMP signaling pathway
100433948 (CACNA1S)
04022 cGMP-PKG signaling pathway
100433948 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100433948 (CACNA1S)
04929 GnRH secretion
100433948 (CACNA1S)
04912 GnRH signaling pathway
100433948 (CACNA1S)
04921 Oxytocin signaling pathway
100433948 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100433948 (CACNA1S)
04924 Renin secretion
100433948 (CACNA1S)
04925 Aldosterone synthesis and secretion
100433948 (CACNA1S)
04927 Cortisol synthesis and secretion
100433948 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100433948 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100433948 (CACNA1S)
04270 Vascular smooth muscle contraction
100433948 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100433948 (CACNA1S)
04725 Cholinergic synapse
100433948 (CACNA1S)
04726 Serotonergic synapse
100433948 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100433948 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100433948 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100433948 (CACNA1S)
05020 Prion disease
100433948 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100433948 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100433948 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100433948 (CACNA1S)
05414 Dilated cardiomyopathy
100433948 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100433948 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pon04040
]
100433948 (CACNA1S)
Ion channels [BR:
pon04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100433948 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
100433948
NCBI-ProteinID:
XP_054379452
Ensembl:
ENSPPYG00000000369
LinkDB
All DBs
Position
1:48439992..48513006
Genome browser
AA seq
1861 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLENPLRKACISVVEWKYPSGPGPPF
ETIILLTIFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFH
QDAYLRSGWNVLDFTIVFLGVFTVILEQVNVIQSHTAPMSSKGAGLDVKALRAFRVLRPL
RLVSGVPSLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFTGTDI
VATVENEEPSPCARTGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEG
WTDVLYWVNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKL
REKQQLDEDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIAGLNKIIQFIRR
WRQWNRIFRWKCHDIVKSKAFYWLVILIVALNTLSIASEHHNQPLWLTHLQDIANRVLLS
LFTVEMLMKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLL
RIFKITKYWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVR
RSNFDNFPQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVCGNYILL
NVFLAIAVDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSTMAKKLEQKPKGEG
IPTTAKLKIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPLSPRPRPLAELQLKEKAVPI
PEASSFFIFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRADSMRNQILK
HFDIGFTSVFTVEIVLKMTTYGAFLHKGSFCRNYFNMLDLLVVAVSLISMGLESSAISVV
KILRVLRVLRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGK
FFRCTDLSKMTEEECRGYYYVYKDGDPKQIELRRREWVHSDFHFDNVLSAMMSLFTVSTF
EGWPQLLYKAIDSNEEDVGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGE
TEYKNCELDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTI
CLGMQHYNQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGS
IIDVILSEIDDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFIKSFQALPYVAL
LIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLFRCATGEAWQEILLAC
SYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLVINLFVAVIMDNFDYLTRDWS
ILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMN
MPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPP
IGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIVQIQAGLRTIEEEAAPEIRR
TVSGDLAAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPPVMANQRPLQFAE
IEMEEMESPVFLEDFPQDPRTNPLARANTNNANANVAYGNSNHSNSHVFSSVHYDREFPE
ETETPATRGGALGQPCRAVGPHSKPCVEMLKGLLTQRAMPRGQAPPAPCQCPRVESPMPE
DRKSSTPGSLHEETPHSRSTGENTSRCSAPATALLIQEALVRGGLGTLAADANFIMATGQ
ALADACQMEPEEVEVMATELLKGREAPEGMASCLGCLNLRSSLGSLDQHQGSQETLIPPR
L
NT seq
5586 nt
NT seq
+upstream
nt +downstream
nt
atggagccatcctcaccccaggatgaaggcctgaggaagaaacagcccaagaagccggtt
cctgagattctgccaaggccacccagggccttgttctgcctgaccctagagaaccccctg
aggaaggcctgcatcagcgttgtagaatggaaatatccttcagggcctgggccgcccttc
gagacgatcatcttgctcaccatctttgccaactgtgtggccctggctgtgtacctgccc
atgccggaagatgacaacaactctctgaacctcggcctggagaagctggagtatttcttc
ctcatcgtcttctcgattgaagccgccatgaagatcattgcctatggcttcttattccac
caggacgcttacctgcgcagtggctggaatgtgctggacttcaccattgtcttcctgggg
gtcttcactgtgattctggaacaggttaacgtcatccaaagccacacagccccaatgagc
agcaaaggagccggcttggatgtcaaggccctcagagccttccgagtgctcagacccctc
cggctggtgtcgggggtgcctagcctgcaggtggtcctgaactccatcttcaaggccatg
ctccccctcttccacatcgccctgctggtcctctttatggtcatcatctatgccatcatc
gggctggagctcttcaagggcaagatgcacaagacctgctacttcactggcacagatatc
gtggccacggtggagaatgaggagccatcgccctgcgccaggacgggctcagggcgccgg
tgcaccatcaatggcagtgagtgccggggcggctggccagggcccaaccatggcatcacc
cacttcgacaacttcggcttctccatgctcaccgtgtaccagtgcatcaccatggaggga
tggactgacgtcctttactgggtcaatgatgccatcgggaatgagtggccctggatctat
tttgtcaccctcattctgctgggatccttcttcatcctcaacctggtgctgggtgtcctg
agcggggaattcaccaaggagcgggagaaggcgaagtccaggggaaccttccagaagctc
cgggagaagcagcagctagatgaggaccttcggggctacatgagctggatcacgcagggc
gaggtcatggacgttgaggacttcagagaaggaaaactgtctttggatgaaggtggctct
gacacagagagcctgtatgaaattgcaggcttgaacaaaatcatccagttcatccggcgt
tggaggcagtggaaccgcatctttcgctggaagtgccatgacatcgtgaagtccaaggcc
ttctactggctggtgattctgatcgttgccctcaacaccctgtctatcgcctcagagcac
cacaaccagcctctctggctgacccatttgcaagacattgccaaccgggtgctgctgtcc
ctcttcaccgtcgagatgctgatgaagatgtatgggctgggcctgcgccagtacttcatg
tccatcttcaaccgcttcgattgcttcgtggtgtgcagcggtatcctggagatcctgctg
gtggagtcgggcgccatgacacccctgggcatctccgtgctccgctgcatccgcctcctg
aggatcttcaagatcaccaaatattggacgtcgctgagcaacctggtggcatctctgctc
aactccatccgctccatcgcctccctgctgctgctgctcttcctcttcatcgtcatcttc
gccctcctgggcatgcagctctttggggggaggtatgactttgaggacacagaagtacgg
cgcagcaactttgacaactttcctcaagcgctcatcagcgtcttccaggtcctgacaggt
gaagactggacctcgatgatgtacaatgggatcatggcctacggagggccgtcctaccct
ggcatgcttgtgtgcatttacttcatcatccttttcgtctgtggcaactacatccttctc
aatgtcttcctggccattgccgtggacaacctggccgaggcggagagcctgacttctgcc
cagaaggccaaggctgaggagagaaaacgcaggaagatgtccaagggtctcccagacaag
tcagaggaggagaagtccacgatggccaagaagctggagcagaaacccaagggtgagggc
atccccaccactgccaagctgaaaatcgatgagtttgaatctaatgtcaacgaggtgaag
gatccctacccctcagctgacttcccaggggatgatgaggaagatgagcccgagatcccg
ctgagcccccgaccacgtcccctggctgagctgcagctgaaagagaaggccgtgcccatt
ccagaagccagctccttcttcatcttcagccccaccaataagatccgtgtcctgtgtcac
cgcatcgtcaatgccacctggttcaccaacttcatcctgctcttcattctccttagcagc
gctgcactggctgcggaagaccccatccgggctgattccatgagaaatcagatccttaaa
cactttgacatcgggttcacctctgtcttcactgtggagattgtcctcaagatgactacc
tatggagccttcctgcacaagggttccttctgccgcaattacttcaacatgctggacctg
ctggtggtggccgtgtccctcatctccatgggacttgagtccagcgccatctctgtggtg
aagatcctgagggtgctgagggtgctccgaccactcagagccatcaacagagccaagggg
ttgaagcacgtggtgcagtgcatgtttgtggccatcagcaccatcgggaacatcgtgctg
gtcactaccctcctacagttcatgtttgcctgcatcggtgtccagctcttcaaggggaag
ttcttcaggtgcaccgacttgtccaagatgacagaggaggagtgcaggggctactactac
gtgtacaaggacggggaccccaagcagatagagctgcgtcgccgcgagtgggtacacagc
gacttccacttcgacaatgtgctctcagccatgatgtccctcttcacggtctccaccttc
gagggatggcctcagctgctgtacaaggccatagactccaatgaggaggacgtgggtccc
atctacaacaaccgtgtggagatggccatcttcttcatcatctacatcatcctcattgcc
ttcttcatgatgaacatcttcgtgggcttcgtcattgtcaccttccaggagcagggagag
actgagtacaagaactgtgagctggacaagaaccagcgccaatgtgtacagtatgccctg
aaggcccgcccactgaggtgctacattcccaaaaacccataccagtaccaggtgtggtac
attgtcacctcctcctactttgaatacctgatgtttgccctcatcatgctcaacaccatc
tgcctcggcatgcagcactacaaccagtcagagcagatgaaccacatctcagacatcctc
aatgtggccttcactatcatcttcaccctggagatgatcctcaagctcatggccttcaag
gccaggggctactttggagacccctggaatgtgtttgacttcctgattgtcattggcagc
atcattgatgtcatcctcagcgagatcgacgacccagacgagagtgcccgcatctccagc
gccttcttccgcctgttccgtgtcatgaggctgatcaagctgctgagccgggcagaggga
gtgcgcaccctcctgtggacgttcatcaagtccttccaggccctaccctacgtggctctg
ctcatcgtcatgctcttcttcatctacgctgtcatcggcatgcagatgtttgggaagatc
gccttggtggatgggacccaaataaaccggaacaacaacttccagaccttcccacaagct
gtgctgctgctcttcaggtgtgcaacaggtgaggcctggcaggagatcctactggcctgc
agctatgggaagctgtgtgacccagagtcagactatgccccaggggaggagtacacatgt
ggcaccaactttgcatactactacttcatcagcttctacatgctctgcgccttcctggtc
atcaacctttttgtggctgtcatcatggacaattttgactacctcacccgggactggtcc
atcctgggccctcatcacctggatgagttcaaggccatctgggcagagtatgacccggag
gctaaggggagaatcaaacacctggacgtggtgaccctgctgagaaggattcagcctcct
ttgggctttggaaagttctgcccacatcgggtagcttgtaagcggctggtgggcatgaac
atgcccctgaacagcgatggcacagtcaccttcaatgccacactcttcgccctggtccgc
acggcactcaagatcaagacggaaggtaactttgagcaggccaacgaggagctgagggcc
atcatcaagaagatctggaagagaaccagcatgaagctcttggaccaggtcatccctcca
ataggagatgatgaggtgacagtggggaagttctatgccacattcctcatccaggagcac
ttccggaagttcatgaaacgccaggaggagtattatggctatcggcccaagaaggacatt
gtacagatccaggcaggactgcggaccattgaggaagaggcagcccccgagatccgtcgc
acggtctcaggagacctggctgctgaggaggagctggagagagccatggtggaggctgcg
atggaggagggaatattccggaggactggaggcctgtttggccaggtggacaacttcctg
gaaaggaccaactccctgccccccgtcatggccaatcagagacccctccagtttgctgag
atagagatggaagagatggagtcacctgtcttcttggaggacttcccacaagatccacgc
accaaccccctggctcgtgccaataccaacaatgccaacgccaatgtcgcctatggcaac
agcaaccatagcaacagccatgtattttccagtgtccactatgacagggagttcccagaa
gagacagagacgcctgctaccagaggaggagcccttggccaaccctgcagggccgtggga
ccccacagcaaaccctgtgtggagatgctgaagggactgctgacccagagggcaatgccc
agaggccaggcacctcctgccccctgccagtgccccagggtggagtcccccatgcctgag
gacagaaagagctccacaccagggtctctgcatgaggagacaccccacagcaggagcacc
ggggagaatacttccaggtgctcagcgccagctacagccctgctgatccaagaggctctg
gttcgagggggcctgggcaccttggcagctgatgcaaacttcatcatggcaacaggccag
gccctggcagatgcctgccaaatggaaccagaggaagtggaggtcatggcaacagagcta
ctgaaaggacgagaggccccagagggcatggccagctgcctgggatgcctgaacctcagg
tcctccctgggcagcctcgaccagcaccagggctcccaggagacccttattcctcccagg
ctgtga
DBGET
integrated database retrieval system
