Pongo abelii (Sumatran orangutan): 100434686
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Entry
100434686 CDS
T01416
Symbol
TOP3B
Name
(RefSeq) DNA topoisomerase 3-beta-1 isoform X1
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon03440
Homologous recombination
pon03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
100434686 (TOP3B)
03460 Fanconi anemia pathway
100434686 (TOP3B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
pon03032
]
100434686 (TOP3B)
03400 DNA repair and recombination proteins [BR:
pon03400
]
100434686 (TOP3B)
Enzymes [BR:
pon01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
100434686 (TOP3B)
DNA replication proteins [BR:
pon03032
]
Eukaryotic type
DNA Topoisomerases
100434686 (TOP3B)
DNA repair and recombination proteins [BR:
pon03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
100434686 (TOP3B)
FA (Fanconi anemia) pathway
100434686 (TOP3B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_TOP3B
Toprim
Motif
Other DBs
NCBI-GeneID:
100434686
NCBI-ProteinID:
XP_002834673
Ensembl:
ENSPPYG00000012014
UniProt:
A0A6D2VV39
LinkDB
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Position
23:26458090..26483893
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AA seq
862 aa
AA seq
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MKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQPVRFKMTSVCGH
VMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMVKFLQVEGRGCDYIVLWLDCDK
EGENICFEVLDAVLPVMNKAHGGEKTVFRARFSSITDTDICNAMACLGEPDHNEALSVDA
RQELDLRIGCAFTRFQTKYFQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETY
WVLQAKVNTDKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPLA
LNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFDLKGSLRQQANH
PYWADTVKQLLAEGINRPRKGHDAGDHPPITPMKSATEAELGGDAWRLYEYITRHFIATV
SHDCKYLQSTISFRIGPELFTCSGKTVLSPGFTEIMPWQSVPLEESLPTCQRGDTFPVGE
VKMLEKQTNPPDYLTEAELITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNL
GIVLVHGYYKIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDSI
AGMDELMEVSFSPLAATGKPLSRCGKCHRFMKYIQAKPSRLHCSHCDETYTLPQNGTIKL
YKELRCPLDDFELVLWSSGSRGKSYPLCPYCYNHPPFRDMKKGMGCNECTHPSCQHSLSM
LGIGQCVECESGVLVLDPTSGPKWKVACNKCNVVAHCFENAHRVRVSADTCSVCEAALLD
VDFNKAKSPLPGDETQHMGCVFCDPVFQELVELKHAASCHPMHRGGPGRRQGRGRGRARR
PPGKPNPRRPKDKMSALAAYFV
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgaagactgtgctcatggttgccgaaaagccgtccttggcacagtcaattgccaaaatc
ctctctagagggagcctgtcctcacacaaagggctgaacggggcctgctcagtccacgag
tacactgggacctttgctggccagccagtgcgcttcaagatgacgtctgtctgtggtcac
gtgatgaccctggatttcctgggaaaatacaacaaatgggacaaagtggaccctgcagaa
ctgttcagccaagctcccacggagaagaaagaagctaaccccaagctgaacatggtgaag
ttcctgcaggtggagggaagaggctgcgactacatcgtgctgtggctggactgcgacaag
gagggggagaacatctgctttgaggttcttgatgctgttctgcctgtcatgaacaaggcc
catggtggcgagaagaccgtattccgggccaggtttagctccatcacggacacagacatc
tgtaatgccatggcctgcctgggcgagcctgaccacaacgaggcgctctcagtggatgct
cgccaggagctggacctgcgaatcggctgtgcgttcaccaggtttcagactaaatatttc
caggggaaatacggtgatttagacagctctctcatctcctttgggccgtgtcagactcca
accctgggattctgcgtggagagacatgataaaatccagtccttcaaaccagagacgtac
tgggtgctgcaggccaaggttaacactgacaaagacagatctctccttttggactgggac
cgagtaagagtgtttgaccgggagatcgcacagatgtttttaaacatgacaaagctggag
aaggaagcccaggtggaggccacaagcaggaaagaaaaggccaagcagagacccctggcc
ctgaacaccgtggagatgctgcgtgtggccagctcttctctgggcatggggccgcagcac
gccatgcagacggctgagcggctctacacgcaaggctacatcagctacccacggacagag
accacccactaccctgagaactttgacctgaagggctctctgcggcagcaggccaaccac
ccctactgggccgacacggtgaagcagttgttagcagaaggtatcaaccgcccgcggaaa
ggccatgacgccggcgaccatccccccatcacccccatgaagtctgccacagaggccgaa
ttagggggtgacgcgtggcggctctatgagtacatcaccagacacttcatcgccacggtc
agccacgactgcaagtacctgcagagcaccatctccttcagaatcgggcccgagctcttc
acctgctccgggaagaccgtcctctcaccaggcttcacagagatcatgccctggcagagc
gtgccgctggaggagagcctgcccacttgccagcggggcgacaccttccctgtgggtgag
gttaagatgctggagaagcagacgaacccgcccgactacctgacggaggccgagctcatc
acgctcatggagaagcatggcatcggcacggatgccagcatccctgtgcatatcaacaac
atctgccagcgcaactatgtcactgtggagagcgggcgccggctcaagcccaccaacctc
ggcatcgtcctggtgcatggctactataagattgatgcagagctggtgctccccaccatc
cgcagtgcagtggagaagcagctgaacctgatcgcccagggcaaggccgactaccgccag
gtcctgggccacaccctggacgtgttcaagaggaagttccactactttgtcgactccatt
gctggcatggatgagttgatggaggtgtctttctcgcccctggcggccacaggcaagccc
ctctcacgctgtgggaagtgccaccgcttcatgaagtacatccaggccaagccaagccgc
ctgcactgctcccactgcgatgagacctacacgctcccccagaacggcaccatcaagctc
tacaaggagctccgctgccctctggatgacttcgagctggtcctgtggtcatcaggctct
cggggcaagagctaccctctgtgcccctactgctacaaccacccacccttccgagacatg
aagaaaggcatgggctgcaacgagtgtacacacccctcctgccagcactcgctgagcatg
ctgggcatcggccagtgcgtggaatgtgagagcggggtgctggtgctggaccccacctcg
ggccccaagtggaaggtggcctgcaacaagtgcaacgtggtagcgcactgcttcgagaac
gcccaccgcgtgcgggtgtccgccgacacctgcagtgtctgtgaggccgccttgcttgat
gtagacttcaacaaggccaagtccccactcccgggcgatgagacgcagcacatgggctgc
gtcttttgtgaccccgtcttccaggagctggtggagctgaagcatgcggcctcctgccac
cccatgcaccgcggtggaccagggagaaggcagggtcgaggacggggccgggccaggagg
ccccctgggaagcccaaccccagacggcccaaggacaagatgtcagccctggccgcctac
ttcgtatga
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