KEGG   Pongo abelii (Sumatran orangutan): 100434731
Entry
100434731         CDS       T01416                                 
Symbol
RPTOR
Name
(RefSeq) regulatory-associated protein of mTOR isoform X1
  KO
K07204  regulatory associated protein of mTOR
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04136  Autophagy - other
pon04140  Autophagy - animal
pon04150  mTOR signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04152  AMPK signaling pathway
pon04211  Longevity regulating pathway
pon04213  Longevity regulating pathway - multiple species
pon04714  Thermogenesis
pon04910  Insulin signaling pathway
pon05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    100434731 (RPTOR)
   04152 AMPK signaling pathway
    100434731 (RPTOR)
   04150 mTOR signaling pathway
    100434731 (RPTOR)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100434731 (RPTOR)
   04136 Autophagy - other
    100434731 (RPTOR)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    100434731 (RPTOR)
  09149 Aging
   04211 Longevity regulating pathway
    100434731 (RPTOR)
   04213 Longevity regulating pathway - multiple species
    100434731 (RPTOR)
  09159 Environmental adaptation
   04714 Thermogenesis
    100434731 (RPTOR)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    100434731 (RPTOR)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pon04131]
    100434731 (RPTOR)
Membrane trafficking [BR:pon04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    100434731 (RPTOR)
SSDB
Motif
Pfam: Raptor_N WD40_CDC20-Fz Beta-prop_EML_2 HEAT WD40_Prp19 WD40_WDHD1_1st WD40 HEAT_2 Beta-prop_WDR90_POC16_2nd WDR55 Cnd1 Beta-prop_TEP1_2nd Beta-prop_EML EIF3I PDS5 WD40_RFWD3 WD40_2
Other DBs
NCBI-GeneID: 100434731
NCBI-ProteinID: XP_024090830
Ensembl: ENSPPYG00000029703
LinkDB
Position
19:96016052..96432009
AA seq 1335 aa
MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV
ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK
QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY
DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC
IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG
RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY
NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL
TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL
QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA
VIVNSYNTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA
HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR
KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV
SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS
FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK
ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD
LPPGRPGTTGPTGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC
DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN
RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD
CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS
SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS
ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD
IHPQADLIACGSVNQFTAIYNGSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS
NDYYISVYSVEKRVR
NT seq 4008 nt   +upstreamnt  +downstreamnt
atggagtccgaaatgctgcaatcgcctcttctgggcctgggggaggaagatgaggctgat
cttacagactggaacctacctttggcttttatgaagaagaggcactgtgagaaaattgaa
ggctccaaatccttagctcagagctggaggatgaaggatcggatgaagacagtcagtgtt
gccttagttttgtgcctgaatgttggtgtggaccctcccgatgtggtgaagaccacgccc
tgtgcgcgcttggaatgctggatcgatcctctgtcgatgggtcctcagaaagctctggaa
accatcggtgcaaatttacagaagcagtacgagaactggcagccaagggcccggtacaag
cagagccttgacccaactgtggatgaagtcaagaagctctgcacgtccttacgtcgcaac
gccaaggaggagcgagtcctctttcactacaatggccacggggtgccccggcccacagtc
aacggggaggtctgggtcttcaacaagaactacacgcagtacatccctctgtccatatat
gacctgcagacgtggatgggcagcccgtcgatcttcgtctacgactgctccaatgctggc
ttgatcgtcaagtccttcaagcagttcgcactacagcgggagcaggagctggaggtagct
gcaatcaacccaaatcaccctcttgctcagatgcctttgcctccatcgatgaaaaactgc
atccagctggcagcctgcgaggccaccgagctgctgcccatgatccccgacctcccggct
gacctgttcacctcctgcctcaccacccccatcaagatcgccttgcgctggttttgcatg
cagaaatgtgtcagtctggtgcctggcgtcacactggatttgatagaaaagatccctggc
cgcctgaacgacaggaggacgcccctgggtgaactcaactggatcttcacagctatcacg
gacaccatcgcgtggaacgtgctcccccgggatctcttccaaaagctcttcagacaggac
ttgctggtggctagtctgtttcgaaattttttattggcggaaaggattatgaggtcgtat
aactgcactcccgtcagcagcccgcgtctgccgcccacgtacatgcacgccatgtggcaa
gcctgggacctggctgttgacatctgtctgtctcagctgccgacgatcatcgaggaaggc
actgcatttcggcacagtccgttcttcgccgagcagctgaccgcattccaggtgtggctc
accatgggcgtggagaaccgaaacccacccgaacagctgcccatcgtcctgcaggtgctg
ttaagccaagtgcaccggctgagagcattggacttgcttggaagatttttggacctgggt
ccctgggcagtgagcctggccttgtctgtcggcatcttcccctatgtgctgaagctgctc
cagagctcggcccgagagctgcggccacttctcgttttcatctgggccaagatcctcgca
gtggacagctcatgccaggcggacctcgtgaaggacaacggccacaagtacttcctgtcg
gtcctggcggacccctacatgccagctgaacacaggaccatgacggctttcattctcgcc
gtgatcgtcaacagctataacacggggcaggaagcctgccttcagggaaacctcattgcc
atctgtctggagcagctcaacgacccgcaccccttgctgcgccagtgggtggccatctgc
cttggcaggatctggcagaacttcgactcggcgaggtggtgcggcgtgagggacagcgct
catgagaagctctacagcctcctctccgaccccattcccgaggtccgctgcgcagcagtc
ttcgcccttggcaccttcgtgggcaactctgcagagaggacggaccactccaccaccatc
gaccacaacgtggccatgatgctggcccagctggtcagcgacgggagccccatggtccgg
aaggagctggtggtggctctgagtcatctcgtggttcagtatgaaagcaatttctgcacc
gtggccctgcagttcatagaagaggaaaagaactacgccttgccttctccagcgaccaca
gagggagggagtttgaccccagtgcgagacagcccgtgcacccccagacttcgttccgtg
agctcctacggaaacatccgtgctgtcgccacagccaggagcctcaacaaatctttgcag
aacctgagtttgacagaggaatctggtggcgcagtggcgttctcccccggaaacctcagc
accagcagcagcgccagcagcaccctgggcagccccgagaatgaggagcacatcctgtcc
tttgagaccatcgacaagatgcgccgcgccagctcctactcctcccttaactccctcatc
ggagtttcctttaacagtgtttacactcagatttggagagtcctgctgcacctggctgct
gacccctatccagaggtctcggacgtggccatgaaagtactcaacagcatcgcctacaag
gccaccgtgaacgcccggccgcagcgcgtcctggacacctcctccctcacacagtcagcc
cccgccagccccaccaacaagggtgtgcacatccaccaggcggggggctcccctccggcg
tccagcaccagcagctccagcctgaccaacgacgtggccaagcagccggtcagccgagac
ttgcctcccggccggccgggcaccacaggccccacgggggcacagtacaccccccactcc
caccagttcccccggacacggaagatgttcgacaagggcccagagcagactgcagacgac
gcagacgatgctgctggacacaaaagtttcatctccgccacggtgcagacggggttctgc
gactggagcgcccgctattttgcccagcctgtcatgaagatcccagaagagcacgacctg
gagagtcagatccgcaaggagcgggagtggcggttcctgcgaaacagccgcgtcaggaga
caggcccagcaagtcatccagaagggcattacgagattggacgaccaaatatttctgaac
aggaaccccggcgtcccctctgtggtgaaattccaccccttcacgccgtgcatcgccgta
gccgacaaggacagcatctgcttttgggactgggagaaaggggagaagctggattatttc
cacaacgggaaccctcggtacacgagggtcactgccatggagtatctgaacggccaggac
tgctcgcttctgctgacggccacagacgatggtgccatcagagtctggaagaattttgct
gatttggaaaagaacccagagatggtgaccgcgtggcaggggctctcagacatgctgcca
acgacgcgaggagctgggatggtggtggactgggagcaggagaccggcctcctcatgagc
tcgggagacgtgcggatcgtccggatctgggacacagaccgtgagatgaaggtgcaggac
atccccacgggcgcagacagctgcgtgacgagtctgtcctgtgattcccaccgctcactc
atcgtggctggcctcggtgacggctccatccgcgtctacgacagaaggatggcactcagc
gaatgccgcgtcatgacgtaccgggagcacacagcctgggtggtaaaggcctccctgcag
aagcgtcccgacggccacatcgtgagcgtgagcgtcaatggagatgtgcgcatctttgat
ccccggatgcccgagtcagtgaatgtgcttcagatcgtgaaggggctgacggcgctggac
atccacccccaggcggacctgatcgcatgtggctccgtcaatcagttcaccgccatctac
aacgggagcggagagctcatcaacaacatcaagtactacgacggcttcatgggccagcgg
gtcggcgccatcagctgcctggccttccacccgcactggcctcacctggccgtgggaagc
aacgactactacatctccgtgtactcggtggagaagcgtgtcagatag

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