Pongo abelii (Sumatran orangutan): 100434875
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Entry
100434875 CDS
T01416
Symbol
CHRNA4
Name
(RefSeq) neuronal acetylcholine receptor subunit alpha-4 isoform X1
KO
K04806
nicotinic acetylcholine receptor alpha-4
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04080
Neuroactive ligand-receptor interaction
pon04082
Neuroactive ligand signaling
pon04725
Cholinergic synapse
pon05033
Nicotine addiction
pon05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
100434875 (CHRNA4)
04082 Neuroactive ligand signaling
100434875 (CHRNA4)
09150 Organismal Systems
09156 Nervous system
04725 Cholinergic synapse
100434875 (CHRNA4)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100434875 (CHRNA4)
09165 Substance dependence
05033 Nicotine addiction
100434875 (CHRNA4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pon04040
]
100434875 (CHRNA4)
Ion channels [BR:
pon04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
100434875 (CHRNA4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_memb
Neur_chan_LBD
Motif
Other DBs
NCBI-GeneID:
100434875
NCBI-ProteinID:
XP_024094544
Ensembl:
ENSPPYG00000011231
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All DBs
Position
21:complement(67795265..67809447)
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AA seq
627 aa
AA seq
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MELGGPGAPRLLPPLLLLLGTGLLRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISD
VVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWR
PDIVLYNNADGDFAVTHLTKAHLFHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFG
SWTYDKAKIDLVNMHSRVDQLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIR
RLPLFYTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTS
LVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKR
PSVVKDNCRRLIESMHKMASAPRFWPEPEGEPPTTSGTQSRHPPSPSFCVPLDVPAEPGP
ACKSSSDQLPALQPPEAEKASPHPSPGPCHPPHSTQAPGLAKARSLSVQHMSSPGEAVEG
SVRCRSRSIQYCVPRDDAAPEADGQAAGALASRKTYSAELPPPDQPSPCKCTCKKEPSSV
SPSATVKARSTKAPPRHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDR
IFLWMFIIVCLLGTVGLFLPPWLAGMI
NT seq
1884 nt
NT seq
+upstream
nt +downstream
nt
atggagctcgggggccccggggcgccgcggctgctgccgccgctgctgctgcttctgggc
accggcctcctgcgcgccagcagccatgtggagacccgggcccacgccgaggagcggctc
ctgaagaaactcttctccggttacaacaagtggtcccgacccgtggccaacatctcagac
gtggtcctcgtccgcttcggcctgtccattgctcagctcattgacgtggatgagaagaac
cagatgatgaccacgaacgtatgggtgaagcaggagtggcacgactacaagctgcgctgg
gacccagctgactacgagaatgtcacctccatccgcatcccctctgagctcatctggcgg
ccggacatcgtcctctacaacaatgccgacggggacttcgcggtcacccacctgaccaag
gcccacctgttccatgacgggcgggtgcagtggactcccccggccatttacaagagctcc
tgcagcatcgacgtcaccttcttcccctttgaccagcagaactgcaccatgaaattcggc
tcctggacctacgacaaggccaagatcgacctggtgaacatgcacagccgcgtggaccag
ctggacttctgggagagtggtgagtgggtcatcgtggacgcggtgggcacctacaacacc
aggaagtatgagtgctgtgccgagatctacccagacatcacctacgccttcgtcatccgg
cggctgccactcttctacaccatcaacctcatcatcccctgcctgctcatctcctgcctc
accgtgctggtcttctacctgccctctgagtgcggcgagaagatcacactgtgcatctcc
gtgctgctgtcactcaccgtcttcctgctgctcatcaccgagatcatcccgtccacctca
ctggtcatcccgctcattggcgagtacctgctgttcaccatgattttcgtcaccctgtcc
atcgtcatcacggtcttcgtgctcaatgtgcaccaccgctcgccgcgcacgcacaccatg
cccacctgggtacgcagggtcttcctggacatcgtgccgcgcctgctcctcatgaagcgg
ccgtccgtggtcaaggacaattgccggcggctcatcgagtccatgcacaagatggccagt
gccccgcgcttctggcccgagccagagggggagccccccaccacgagcggcacccagagc
cggcatccgccctcaccgtccttctgcgtccccctggatgtgccagctgagcctgggcct
gcctgcaagtcatcctccgaccagctccctgctctgcagcccccagaagctgagaaagcc
agcccccacccctcgcctggaccctgccacccaccccacagcacccaggcaccagggctg
gccaaagccaggtccctcagcgtccagcacatgtccagccctggcgaagcagtagaaggc
agcgtccggtgccggtctcggagcatccagtactgtgttccccgagacgatgctgccccc
gaggcagatggccaggctgccggcgccctggcctctcgcaagacctactcggctgagctc
ccacccccagaccagccctctccgtgcaaatgcacatgcaagaaggagccctcttcggtg
tccccgagcgccacggtcaaggcccgcagcaccaaagcgccgccccggcacctgcccctg
tcgccggccctgacccgggcggtggagggtgtccagtacattgcagaccacctgaaggcc
gaagacacagacttctcggtgaaggaggactggaagtacgtggccatggtcatcgaccgc
atctttctctggatgttcatcatcgtctgcttgctggggaccgtgggcctcttcctgccg
ccctggctggctggcatgatctag
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