Pongo abelii (Sumatran orangutan): 100435140 Help Entry 100435140         CDS       T01416                                  Symbol PKLR Name (RefSeq) pyruvate kinase PKLR isoform X2   KO K12406   pyruvate kinase isozymes R/L [EC:2.7.1.40] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00010   Glycolysis / Gluconeogenesis pon00620   Pyruvate metabolism pon01100   Metabolic pathways pon01200   Carbon metabolism pon01230   Biosynthesis of amino acids pon04910   Insulin signaling pathway pon04930   Type II diabetes mellitus pon04932   Non-alcoholic fatty liver disease pon04950   Maturity onset diabetes of the young Module pon_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate pon_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100435140 (PKLR)    00620 Pyruvate metabolism     100435140 (PKLR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100435140 (PKLR)  09160 Human Diseases   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100435140 (PKLR)    04950 Maturity onset diabetes of the young     100435140 (PKLR)    04932 Non-alcoholic fatty liver disease     100435140 (PKLR)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100435140 (PKLR) Enzymes [BR:pon01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      100435140 (PKLR) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    100435140 (PKLR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C IMPDH HpcH_HpaI Motif Other DBs NCBI-GeneID:  100435140 NCBI-ProteinID:  XP_024102956 Ensembl:  ENSPPYG00000010643 LinkDB All DBs Position 1:95288273..95299223 Genome browser AA seq 604 aa AA seqDB search MSIQKNISSLQLRSWVSKSQRDLAKSILIGAPGAQPGLTPLTTQQCGADPQRGRPREVCS GMEGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSI IATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAASPLSYRP VAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRV VPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVR DLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVS DGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSD VANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRD PTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCR GVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRV LSIS NT seq 1815 nt NT seq  +upstreamnt  +downstreamnt atgtcgatccagaagaacatatcatccctgcagcttcggtcatgggtctctaagtcccaa agagacttagcaaagtccatcctgattggggctccaggagcccagccgggcctcacgcct ctgacaacccaacagtgtggagcagacccacaaagagggagacccagagaggtgtgcagt ggcatggaagggccagcggggtatctgcggcgggccagtgtggcccaactgacccaggag ctgggcactgccttcttccagcagcagcagctgccagctgctatggcagacaccttcctg gaacacctctgcctactggacatcgactccgagcccgtggctgctcgcagtaccagcatc attgccaccatcgggcctgcatctcgctccgtggagcgcctcaaggagatgatcaaggcc gggatgaacattgcgcgactcaacttctcccacggctcccacgagtaccacgctgagtcc atcgccaacgtccgggaggcggtggagagctttgcagcttccccgctcagctaccggccc gtggccatcgccctggacaccaagggaccggagatccgcactgggatcctgcaggggggt ccagagtcggaagtggagctggtgaagggctcccaagtgctggtgactgtggaccccgcg ttccggacgcgggggaacgcgaacaccgtgtgggtggactaccccaatattgtccgggtc gtgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtccagaaa atcggcccagagggactggtgacccaagtggagaacggtggcgtcctgggcagccggaag ggcgtgaacttgccaggggcccaggtggacttgcccgggctgtccgagcaggacgtccga gacctgcgcttcggggtggagcatggcgtggacatcgtctttgcctcctttgtgcggaaa gccagcgacgtggctgccgtcagggctgctctgggtccggaaggacacggcatcaagatc atcagcaaaattgagaaccacgaaggcgtgaagaggtttgatgaaatcctggaggtgagc gacggcatcatggtggcacggggggacctaggcatcgagatcccagcagagaaggttttc ctggctcagaagatgatgatcgggcgctgcaacttggccggcaagcctgttgtctgtgcc acacagatgctggagagcatgattaccaagccccggccaacgagggcagagacaagcgat gtcgccaacgctgtgctggatggggctgactgcatcatgctgtcaggggagactgccaag ggcaacttccctgtggaagccgtgaagatgcagcatgcgattgcccgggaggcagaggcc gcagtgtaccaccggcagctgtttgaggagctacgtcgggcagcgccactaagccgtgat cccactgaggtcaccgccattggcgctgtggaggctgccttcaagtgctgtgctgctgcc atcattgtgctgaccacaactggccgctcagcccagcttctgtctcggtaccgacctcgg gcagcagtcattgctgtcacccgctctgcccaggctgcccgccaggtccacttatgccga ggagtcttccccttgctttaccgtgaacctccagaagccatatgggcagatgatgtagat cgccgggtgcaatttggcattgaaagtggaaagctccgtggcttcctccgtgttggagac ctggtgattgtggtgacaggctggcgacctggctccggctacaccaacatcatgcgggtg ctgagcatatcctga

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