Pongo abelii (Sumatran orangutan): 100436584 Help Entry 100436584         CDS       T01416                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00220   Arginine biosynthesis pon00330   Arginine and proline metabolism pon01100   Metabolic pathways pon04020   Calcium signaling pathway pon04066   HIF-1 signaling pathway pon04146   Peroxisome pon04371   Apelin signaling pathway pon04926   Relaxin signaling pathway pon05010   Alzheimer disease pon05014   Amyotrophic lateral sclerosis pon05022   Pathways of neurodegeneration - multiple diseases pon05133   Pertussis pon05140   Leishmaniasis pon05142   Chagas disease pon05145   Toxoplasmosis pon05146   Amoebiasis pon05152   Tuberculosis pon05200   Pathways in cancer pon05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     100436584 (NOS2)    00330 Arginine and proline metabolism     100436584 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     100436584 (NOS2)    04066 HIF-1 signaling pathway     100436584 (NOS2)    04020 Calcium signaling pathway     100436584 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     100436584 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     100436584 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100436584 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     100436584 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     100436584 (NOS2)    05152 Tuberculosis     100436584 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     100436584 (NOS2)    05145 Toxoplasmosis     100436584 (NOS2)    05140 Leishmaniasis     100436584 (NOS2)    05142 Chagas disease     100436584 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     100436584 (NOS2)    05014 Amyotrophic lateral sclerosis     100436584 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     100436584 (NOS2) Enzymes [BR:pon01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      100436584 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  100436584 NCBI-ProteinID:  XP_054391579 Ensembl:  ENSPPYG00000008080 UniProt:  H2NT20 LinkDB All DBs Position 19:complement(41747589..41790172) Genome browser AA seq 1153 aa AA seqDB search MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHSLSKQQNESPQPL VETGKKSPESLVKLDATALSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG RFDVVPLVLQADGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYNLSCLEEERLLLVVTSTFGNGDCPG NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDL SKALSSMHAKNVFTLRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ PALVQGILERVVDGPAPHQTVRLEVLDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ LLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNNLKPQDPVPCF VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQRKGVRGGRMTLVFGCRRPD EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHEEPGHLY VCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDT AAVQPSSLEMSVL NT seq 3462 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccttggaaatttctgttcaagaccaaattccaccagtatgcaatgaatggg gaaaaagacatcaacaacaacgtggagaaagccccctgtgccacctccagtccagtgaca caggatgacctccagtatcacagcctcagcaagcagcagaatgagtccccgcagcccctc gtggagacgggaaagaagtctccagaatctctggtcaagctggatgcaaccgcattgtcc tccccacggcatgtgaggatcaaaaactggggcagcgggatgactttccaagacacactt caccataaggccaaagggattttaacttgcaggtccaaatcttgcctggggtccattatg actcccaaaagtttgaccagaggacccagggacaagcctacccctccagatgagcttcta cctcaagctatcgaatttgtcaaccaatattacggctccttcaaagaggcaaaaatagag gaacatctggccagagtggaagcagtaacaaaggagatagaaacaacaggaacctaccaa ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaatgccccacgctgc attgggaggatccagtggtccaacctgcaggtctttgatgcccgcagctgttccactgcc cgggaaatgtttgaacacatctgcagacacgtgcgttactccaccaacaatggcaacatc aggtcggccatcaccgtgttcccccagcggagcgatggcaagcacgacttccgggtgtgg aatgctcagctcatccgctatgctggctaccagatgccagatggcagcatcagaggggac cctgccaacgtggaattcactcagctgtgcattgacctgggctggaagcccaagtacggc cgctttgatgtggtccccctggtcctgcaggctgatggccgtgaccctgagctcttcgaa attccacctgaccttgtgcttgaggtggccatggaacatcccaaatacgagtggtttcgg gaactggagctaaagtggtacgccctgcctgcagtggccaacatgctgctcgaggtgggc ggcctggagttcccagggtgccccttcaatggctggtacatgggcacagagatcggagtc cgggacttctgtgacgtccagcgctacaacatcctggaggaagtgggcaggagaatgggc ttggaaacgcacaagctggcctcactctggaaagaccaggctgtcgttgagatcaacatt gctgtgctccatagtttccagaagcagaatgtgaccatcatggaccaccactcggctgca gaatccttcatgaagtacatgcagaatgaataccggtcccgtgggggctgcccggcagac tggatttggctggtccctcccatgtctgggagcatcacccccgtgtttcaccaggagatg ctgaactacgtcctgtcccctttctactactatcaggtagaggcctggaaaacccatgtc tggcaggacgagaagcggagacccaagagaagggagattccgttgaaagtcttggtcaaa gctgtgctctttgcctgtatgctgatgcgcaagacaatggcgtcccgagtcagagtcacc atcctctttgcgacagagacaggaaaatcagaggcgctggcctgggacctgggggccttg ttcagctgtgccttcaaccccaaggttgtctgcatggataagtacaacctgagctgcctg gaggaggagcggctgctgttggtggtgaccagtacgtttggcaacggagactgccccggc aatggagagaaactgaagaaatcgctcttcatgctgaaagagctcaacaacaaattcagg tacgctgtgtttggccttggctccagcatgtaccctcggttctgcgcctttgctcatgac attgatcagaagctgtcccacctgggggcctctcagctcaccccgatgggagaaggggat gagctcagtggacaggaggacgccttccgcagctgggccgtgcaaaccttcaaggcagcc tgtgagacgtttgatgtccgaggcaaacagcacattcagatccccaagctctacacctcc aatgtgacctgggacccgcaccactataggctcgtgcaggactcacagcctttggacctc agcaaagccctcagcagcatgcacgccaagaacgtgttcaccctgaggctcaaatctcgg cagaatctacaaagtccgacatccagccgtgccaccatcctggtggaactctcctgtgag gatggccaaggcctgaactacctgccgggggagcaccttggggtttgcccaggcaaccag ccggccctggtccaaggcatcctggagcgagtggtggacggccccgcaccccaccagaca gtgcgcctggaggtcctggatgagagcggcagctactgggtcagtgacaagaggctgccc ccctgctcactcagccaggccctcacctacttcctggacatcaccacacccccaacccag ctgctgctccaaaagctggcccaggtggccacagaagagcctgagagacagaggctggag gccttgtgtcagccctcagagtacagcaagtggaagttcaccaacagccccacgttcctg gaggtgctagaagagttcccgtccctgcgggtgtctgctggcttcctgctttcccagctc cccattctgaagcccaggttctactccatcagctcctcccgggatcacacgcccacggag atccacctgactgtggccgtggtcacctaccacacccgagatggccagggtcccctgcac cacggcgtctgcagcacatggctcaacaacctgaagccccaagacccagtgccctgcttt gtgcggaatgccagcggcttccacctccccgaggacccctcccatccttgcatcctcatc gggcctggcacaggcatcgctcccttccgcagtttctggcagcagcggctccatgactcc cagcgcaagggagtgcggggaggccgcatgaccttggtgtttgggtgccgccgcccagat gaggaccacatctaccaggaggagatgctggagatggcccagaagggggtgctgcatgcg gtgcacacagcctattcccgcctgcctggcaagcccaaggtctatgttcaggacatcctg cggcagcagctggccagcgaggtgctccgtgtgctccacgaggagccgggccacctctat gtttgcggagatgtgcgcatggcccgggacgtggcccacaccctgaagcagctggtggct gccaagctgaaattgaatgaggagcaggtcgaggactatttctttcagctcaagagccag aagcgctatcatgaagatatctttggtgctgtatttccctacgaggcgaagaaggacacg gcggcggtgcagcccagcagcctggagatgtcagtgctctga

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