Pongo abelii (Sumatran orangutan): 100439073 Help Entry 100439073         CDS       T01416                                  Symbol TOP2B Name (RefSeq) DNA topoisomerase 2-beta   KO K03164   DNA topoisomerase II [EC:5.6.2.2] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01524   Platinum drug resistance Brite KEGG Orthology (KO) [BR:pon00001]  09160 Human Diseases   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100439073 (TOP2B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03032 DNA replication proteins [BR:pon03032]     100439073 (TOP2B)    03036 Chromosome and associated proteins [BR:pon03036]     100439073 (TOP2B) Enzymes [BR:pon01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.2  DNA topoisomerase (ATP-hydrolysing)      100439073 (TOP2B) DNA replication proteins [BR:pon03032]  Eukaryotic type   DNA Topoisomerases    100439073 (TOP2B) Chromosome and associated proteins [BR:pon03036]  Eukaryotic type   Chromosome condensation proteins    Other regulators of chromosome condensation     100439073 (TOP2B)   Centrosome formation proteins    Centriole proteins     100439073 (TOP2B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT Toprim HATPase_c DUF7180 Motif Other DBs NCBI-GeneID:  100439073 NCBI-ProteinID:  NP_001127186 Ensembl:  ENSPPYG00000014061 UniProt:  Q5REX2 LinkDB All DBs Position 2:129009587..129076361 Genome browser AA seq 1620 aa AA seqDB search MAKSGGCGAGAGVGGGNGALTWVNNAAKKEESETANKNDSSKKLSVERVYQKKTQLEHIL LRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTC IKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNG YGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLS KFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGV ALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKK NKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASN CGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDS AKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGQQYKKSYDD AESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNK QELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPE DDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELI LFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQAL MMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLFPAVDDNL LKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDP HPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLN GTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDH MGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITI ENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSGPDFNYI LNMSLWSLTKEKVEELIKQRDAKGRDVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED ILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLD TAAVKVEFDEEFSGAPVEGAGEEALTPSAPMNKGPKPKREKKEPGTRVRKTPTSSGKPSA KKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDD DDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKKSQDFGN LFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTAPK PKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTSK TTSKKPKKTSFDQDSDVDIFPSEFPTEPPSLPRTGRARKEVKYFAESDEEEEDVDFAMFN NT seq 4863 nt NT seq  +upstreamnt  +downstreamnt atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcaacggggcactg acctgggtgaacaatgctgcaaaaaaagaagagtcagaaactgccaacaaaaatgattct tcaaagaagttgtctgttgagagagtgtatcagaagaagacacaacttgaacacattctt cttcgtcctgatacatacattgggtcagtggagccattgacgcagttcatgtgggtgtat gatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatacaagatc tttgacgaaattttggttaatgctgctgacaataaacagagggataagaacatgacttgt attaaagtttctattgatcctgaatctaacattataagcatttggaataatgggaaaggc attccagtagtagaacacaaggtagagaaagtttatgttcctgctttaatttttggacag cttttaacatccagtaactatgacgatgatgagaaaaaagttacaggtggtcgtaatggt tatggtgcaaaactttgtaatattttcagcacaaagtttacagtagaaacagcttgcaaa gaatacaaacacagttttaagcagacatggatgaataatatgatgaagacttctgaagcc aaaattaaacattttgatggtgaagattacacatgcataacattccaaccagatctgtcc aaatttaagatggaaaaacttgacaaggatattgtggccctcatgactagaagggcatat gatttggctggttcatgtagaggggtcaaggtcatgtttaatggaaagaaattgcctgta aatggatttcgcagttatgtagatctttatgtgaaagacaaattggatgaaactggggtg gccctgaaagttattcatgagcttgcaaatgaaagatgggatgtttgtctcacattgagt gaaaaaggattccagcaaatcagctttgtaaatagtattgcaactacaaaaggtggacgg cacgtggattatgtggtagatcaagttgttggtaaactgattgaagtagttaagaaaaag aacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccatatatgggtttttatt aattgccttattgaaaatccaacttttgattctcagactaaggaaaacatgactctgcag cccaaaagttttgggtctaaatgccagctgtcagaaaaattttttaaagcagcctctaat tgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcagctgaat aagaagtgttcatcagtaaaatacagtaaaatcaaaggtattcccaaactggatgacgct aatgatgctggtggtaaacattccctggagtgtacactgatattaacagagggagactct gccaaatcactggctgtgtctggattaggtgtgattggacgagacagatacggagttttt ccactcaggggcaaaattcttaatgtacgggaagcttctcataaacagatcatggaaaat gctgaaataaataatattattaaaatagttggtcagcaatataagaaaagttacgatgat gcagaatctctgaaaaccttacgctatggaaagattatgattatgaccgatcaggatcaa gatggttctcacataaaaggcctgcttattaatttcatccatcacaattggccatcactt ttgaagcatggttttctcgaagagttcattactcctattgtaaaggcaagcaaaaataag caggaactttccttctacagtattcctgaatttgatgaatggaaaaaacatatagaaaac cagaaagcctggaaaataaagtactataaaggattgggtactagtacagctaaagaggca aaggaatattttgctgatatggaaaggcatcgcatcttgtttagatatgctggtcctgaa gatgatgctgccattaccttggcatttagtaagaagaagattgatgacagaaaagaatgg ttaacaaattttatggaagaccggagacagcgtaggctacatggcttaccagagcaattt ttatatggtactgcaacaaagcatttgacttataatgatttcatcaacaaggaattgatt ctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggctttaaacct ggccagcggaaagttttatttacctgtttcaagaggaatgataaacgtgaagtaaaagtt gcccagttggctggctctgttgctgagatgtcggcttatcatcatggagaacaagcattg atgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaacttgctt cagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagtcctcgt tatattttcacaatgttaagctctttagcaaggctttttcctgctgtggatgacaacctc cttaagttcctttatgatgataatcaacgtgtagagcctgagtggtatattcctataatt cccatggttttaataaatggtgctgagggcattggtactggatgggcttgtaaactaccc aactatgatgctagggaaattgtgaacaatgtcagacgaatgctagatggcctggatcct catcccatgcttccaaactacaaaaactttaaaggcacgattcaagaacttggtcaaaac cagtatgcagtcagtggtgaaatatttgtagtggacagaaacacagtagaaattacagag cttccagttagaacttggacacaggtatataaagaacaggttttagaacctatgctaaat ggaacagacaaaacaccagcgttaatttctgattataaagaatatcatactgacacaact gtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagctgctggactg cataaagtttttaaacttcaaactactcttacttgtaattccatggtactctttgatcat atgggatgtctgaagaaatatgaaactgtgcaagacattctgaaagaattctttgattta cgattaagttattacggtttacgtaaggagtggcttgtgggaatgttgggagcagaatct acaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaaaattactata gagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttatgaatctgac ccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggatgaaacacaaaac cagcatgatgatagttcctccgattcaggaactccttcaggcccagattttaattatatt ttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgattaaacagaga gatgcaaaagggcgagatgtcaatgatcttaaaagaaaatctccttcagatctttggaaa gaagatttagcagcatttgttgaagaattggataaagtggaatctcaagaacgagaagat attctggctggaatgtctggaaaagcaattaaaggtaaagttggcaaacctaaggtgaag aaactccagttggaagagacaatgccctcaccttatggcagaagaataattcctgaaatt acagctatgaaggcagatgccagcaaaaagttgctgaagaagaagaagggtgatcttgat actgcagcagtaaaagtggaatttgatgaagaattcagtggagcgccagtagaaggtgca ggagaagaggcattgactccatcagctcctatgaataaaggccccaaacccaaaagggag aagaaggagcctggtaccagagtgagaaaaacacctacatcatctggtaaacctagtgca aagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtcagaaagtgatttg gaagaaacagaacctgtggttattccaagagattctttgcttaggagagcagcagccgaa agacctaaatacacatttgatttctcagaagaagaggatgatgatgctgatgatgatgat gatgacaataatgatttagaggaattgaaagttaaagcatctcccataacaaatgatggg gaagatgaatttgttccttcagatgggttagataaagatgaatatacattttcaccaggc aaatcaaaagccactccagaaaaatctttgcatgacaaaaaaagtcaggattttggaaat ctcttctcatttccttcatattctcagaagtcagaagatgattcagctaaatttgacagt aatgaagaagattctgcttctgttttttcaccatcatttggtctgaaacagacagataaa gttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagatacagcccctaag cccaagagagccccaaaacagaagaaggtagtagaggctgtaaactctgactcggattca gaatttggcattccaaagaagactacaacaccaaaaggtaaaggccgaggggcaaagaaa aggaaagcatctggctctgaaaatgaaggcgattataaccctggcaggaaaacatccaaa acaacaagcaagaaaccgaagaagacatcttttgatcaggattcagatgtggacatcttc ccctcagagttccctactgagccaccttctctgccacgaaccggtcgggctaggaaagaa gtaaaatattttgccgagtctgatgaagaagaagaagacgttgattttgcaatgtttaat taa

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