Pongo abelii (Sumatran orangutan): 100440043 Help Entry 100440043         CDS       T01416                                  Symbol NF1 Name (RefSeq) neurofibromin isoform X3   KO K08052   neurofibromin 1 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01521   EGFR tyrosine kinase inhibitor resistance pon04010   MAPK signaling pathway pon04014   Ras signaling pathway Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100440043 (NF1)    04014 Ras signaling pathway     100440043 (NF1)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100440043 (NF1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PH_NF1 RasGAP CRAL_TRIO_2 CRAL_TRIO MIF4G_like_2 Motif Other DBs NCBI-GeneID:  100440043 NCBI-ProteinID:  XP_024091410 Ensembl:  ENSPPYG00000008147 LinkDB All DBs Position 19:complement(45423031..45705976) Genome browser AA seq 2839 aa AA seqDB search MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL REILICRNKFLLKNKQADRSSCHFLLFYGVGCDIPSSGNTSQMSMDHEELLRTPGASLRK GKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFRHLCEEADIR CGVDEVSVHNLLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWEDT HAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWINM TGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRLLS LMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNTQF VEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVE VMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVSLL AGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDESTQTGGRKRGMSRRLAS LRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAETV LADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLWNM FSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSADWQHVSFE VDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLNKA TVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERGLK LMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSFIS DGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTHWS SLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQING DLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVYIY NCNSWVREYTKYHERLLTGLKGSKRLVFIDCPGKLAEHIEHEQQKLPAATLALEEDLKVF HNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQFT LTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIALL NLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAANEP HLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKLIT MTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVALAS GNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAHL PYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLPK FYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMRDI PTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLK GPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQ NLHTLDSLRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRH PSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHRKS LLLTDISMENVPMDTYPIHHGDPTYRTLKETQPWSSPKGSEGYLAATYPTVGQTSPRARK SMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYEME TQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRILY EYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQYQT SYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTPTS PYPPALQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSASQ VQKQRSAGSFKRNSIKKIV NT seq 8520 nt NT seq  +upstreamnt  +downstreamnt atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag cttccaataaaaacaggacagcagaacacgcataccaaagtcagtactgagcacaacaag gaatgtctaatcaatatttccaaatacaagttttctttggttataagcggcctcactact attttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttatat ctctctcagttgataatattggatacactggaaaaatgtcttgctgggcaaccaaaggac acaatgagattagatgaaacgatgctggtcaaacagttgctgccagaaatctgccatttt cttcacacctgtcgtgaaggaaaccagcatgcagctgaacttcggaattctgcctctggg gttttattttctctcagctgcaacaacttcaatgcagtctttagtcgcatttctaccagg ttacaggaattaactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta cagtatatcaatgtggattgtgcaaaattaaaacgactcctgaaggaaacagcatttaaa tttaaagccctaaagaaggttgcgcagttagcagttataaatagcctggaaaaggcattt tggaactgggtagaaaattatccagatgaatttacaaaactataccagatcccacagact gatatggctgaatgtgcagaaaagctatttgacttggtggatggttttgctgaaagcacc aaacgtaaagcagcagtttggccactacaaatcattctccttatcttgtgtccagagata atccaggatatatccaaagatgtggttgatgaaaacaacatgaataagaagttatttctg gacagtctacgaaaagctcttgctggccatggaggaagtaggcagctgacagaaagtgct gcaattgcctgtgtcaaactgtgtaaagcaagtacctacatcaattgggaagataactct gtcattttcctacttgttcagtccatggtggttgatcttaagaacctgctttttaatcca agtaagccattctcaagaggcagtcagcctgcagatgtggatctaatgattgactgcctt gtttcttgctttcgtataagccctcacaacaaccaacactttaagatctgcctggctcag aattcaccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat tctgcattggattggtggcctaagattgatgctgtgtattgtcactcggttgaacttcga aatatgtttggtgaaacacttcataaagcagtgcaaggttgtggagcacacccagcaata cgaatggcaccgagtcttacatttaaagaaaaagtaacaagccttaaatttaaagaaaaa cctacagacctggagacaagaagctataagtatcttctcttgtccatggtgaaactaatt catgcagatccaaagctcttgctttgtaatccaagaaaacaggggcccgaaacccaaggc agtacagcagaattaattacagggctcgtccaactggtccctcagtcacacatgccagag attgctcaggaagcaatggaggctctgctggttcttcatcagttagatagcattgatttg tggaatcctgatgctcctgtagaaacattttgggagattagctcacaaatgcttttttac atctgcaagaaattaactagtcatcaaatgcttagtagcacagaaattctcaagtggttg cgggaaatattgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagt tcctgtcactttctccttttttacggggtaggatgtgatattccttctagtgggaatacc agtcaaatgtccatggatcatgaagaattactacgtactcctggagcctctctccggaag ggaaaagggaactcctctatggatagtgcagcaggatgcagtggaacccccccgatttgc cgacaagcccagaccaaactagaagtggccctgtacatgtttctgtggaaccctgacact gaagctgttctggttgccatgtcctgtttccgccacctctgtgaggaagcagatatccgg tgtggggtggatgaagtgtcagtgcataacctcttgcccaactataacacattcatggag tttgcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaagagtaatg gcactgctgaggcgcattgagcatcccactgcaggaaacactgaggcttgggaagataca catgcaaaatgggaacaagcaacaaaactaatccttaactatccaaaagccaaaatggaa gatggccaggctgctgaaagccttcacaagaccattgttaagaggcgaatgtcccatgtg agtggaggaggatccatagatttgtctgacacagactccctacaggaatggatcaacatg actggcttcctttgtgcccttgggggagtgtgcctccagcagagaagcaattctggcctg gcaacctatagcccacccatgggtccagtcagtgaacgtaagggttctatgatttcagtg atgtcctcagagggaaacgcagatacacctgtcagcaaatttatggatcggctgttgtcc ttaatggtgtgtaaccatgagaaagtgggacttcaaatacggaccaatgttaaggatctg gtgggtctagaattgagtcctgctctgtatccaatgctatttaacaaattgaagaatacc atcagcaagttttttgactcccaaggacaggttttattgactgataccaatactcaattt gtagaacaaaccatagctataatgaagaacttgctagataatcatactgaaggcagctct gaacatctagggcaagctagcattgaaacaatgatgttaaatctggtcaggtatgttcgt gtgcttgggaatatggtccatgcaattcaaataaaaacgaaactgtgtcaattagttgaa gtaatgatggcaaggagagatgacctctcattttgccaagagatgaaatttaggaataag atggtagaatacttgacagactgggttatggggacatcaaaccaagcagcagatgatgat gtaaaatgtcttacaagagatttggaccaggcaagcatggaagcagtagtttcacttcta gctggtctccctctgcagcctgaagaaggagatggtgtggaattgatggaagccaaatcg cagttatttcttaaatacttcacattatttatgaaccttttgaatgactgcagtgaagtt gaagatgaaagtacacaaacaggtggcaggaaacgtggcatgtctcggaggctggcatca ctgaggcactgtacagtccttgcaatgtcaaacttactcaatgccaacgtagacagtggt ctcatgcactccataggcttaggttaccacaaggatctccagacaagagctacatttatg gaagttctgacaaaaatccttcaacaaggcacagaatttgacacacttgcagaaacggta ttggctgatcggtttgagagattggtggaactggtcacaatgatgggtgatcaaggagaa ctccctatagcgatggctctggccaatgtggttccttgttctcagtgggatgaactagct cgagttctggttactctgtttgattctcggcatttactctaccaactgctctggaacatg ttttctaaagaagtagaattggcagactccatgcagactctcttccgaggcaacagcttg gccagtaaaataatgacattctgtttcaaggtatatggtgctacctatctacaaaaactc ctggatcctttattacgaattgtgatcacatccgctgattggcaacatgttagctttgaa gtggatcctaccaggttagaaccatcagagagccttgaggaaaaccagcggaacctcctt cagatgactgaaaagttcttccatgccatcatcagttcctcttcagaattcccccctcaa cttcgaagtgtgtgccactgtttataccaggcaacttgccactccctactgaataaagct acagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgtttccctcagaac agcatcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccattgtctca ccgtatgaagcagggattttagataaaaagccaccacctagaatcgaaagaggcttgaag ttaatgtcaaagatacttcagagtattgccaatcatgttctcttcacaaaagaagaacat atgcggcctttcaatgattttgtgaaaagcaactttgatgcagcacgaaggtttttcctt gatatagcatctgattgtcctacaagtgatgcagtaaatcatagtctttccttcatcagt gacggcaatgtgcttgctttacatcgtctactctggaacaatcaggagaaaattggccag tatctttccagcaacagggatcataaagctgttggaagacgaccttttgataagatggca acacttcttgcatacctgggtcctccagagcacaaacctgtggcagatacacactggtcc agccttaaccttaccagttcaaagtttgaggaatttatgactaggcatcaggtacatgaa aaagaagaattcaaagctttgaaaacgttaagtattttctaccaagctgggacttccaaa gctgggaatcctattttttattatgttgcacggaggttcaaaactggtcaaatcaatggt gatttgctgatataccatgtcttactgactttaaagccatattatgcaaagccatatgaa attgtagtggaccttacccataccgggcctagcaatcgctttaaaacagactttctctct aagtggtttgttgtttttcctggctttgcttacgacaacgtctccgcagtctatatctat aactgtaattcctgggtcagggagtacactaagtatcatgagcggctgctgactggcctc aaaggtagcaaaaggcttgttttcatagactgtcctgggaaactggctgagcacatagag catgaacaacagaaactacctgctgccaccttggctttagaagaggacctgaaggtattc cacaatgctctcaagctagctcacaaagacaccaaagtttctattaaagttggttctact gctgtccaagtaacctcagcagagcgaacaaaagtcctagggcaatcagtctttctaaat gacatttattatgcttcggaaattgaagaaatctgcctagtagatgagaaccagttcacc ttaaccattgcaaaccagggcacaccgctcaccttcatgcaccaggagtgtgaagccatt gtccagtctatcattcatatccggactcgctgggaactgtcacagcccgactctatcccc caacacaccaagattcggccaaaagatgtccctgggacactgctcaatatcgcattactt aatttaggcagttctgacccgagtttacggtcagctgcctataatcttctgtgtgcctta acttgtacctttaatttaaaaatcgagggccagttactagagacatcaggtttatgtatt cctgccaacaacaccctctttattgtctctattagtaagacactggcagccaatgagcca caccttacattagaatttttggaagagtgtatttctggatttagcaaatctagtattgaa ttgaaacacctttgtttggaatacatgactccatggctgtcaaatctagttcgtttttgc aagcataatgatgatgccaaacgacaaagagttactgctattcttgacaagctgataaca atgaccatcaatgaaaaacagatgtacccatctattcaagcaaaaatatggggaagcctt gggcagattacagatctgcttgatgttgtactagacagtttcatcaaaaccagtgcaaca ggtggcttgggatcaataaaagctgaggtgatggcagatactgctgtagctttggcttct ggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataattgacaag acatgcttatctccaactcctactttagaacaacatcttatgtgggatgatattgctatt ttagcacgctacatgctgatgctgtccttcaacaattcccttgatgtggcagctcatctt ccctacctcttccacgttgttactttcttagtagccacaggtccgctctcccttagagct tccacacatggactggtcattaatatcattcactctctgtgtacttgttcacagcttcat tttagtgaagagaccaagcaagttttgagactcagtctgacagagttctcattacccaaa ttttacttgctgtttggcattagcaaagtcaagtcagctgctgtcattgccttccgttcc agttaccgggacaggtcattctctcctggctcctatgagagagagacttttgctttgaca tccttggaaacagtcacagaagctttgttggagatcatggaggcatgcatgagagatatt ccaacgtgcaagtggctggaccagtggacagaactagctcaaagatttgcattccaatat aatccatccctgcaaccaagagctcttgttgtctttgggtgtattagcaaacgagtgtct catgggcagataaagcagataatccgtattcttagcaaggcacttgagagttgcttaaaa ggacctgacacttacaacagtcaagttctgatagaagctacagtaatagcactaaccaaa ttacagccacttcttaataaggactcgcctctgcataaagccctcttttgggtagctgtg gctgtgctgcagcttgatgaggtcaacttgtattcagcaggcaccgcacttcttgaacaa aacctgcatactttagatagtctccgtatattcaatgacaagagtccagaggaagtattt atggcaatccggaatcctctggagtggcactgcaagcaaatggatcattttgttggactc aatttcaactctaactttaactttgcattggttggacaccttttaaaagggtacaggcat ccttcacctgccattgttgcaagaacagtcagaattttacatacactactaactctggtt aacaaacacagaaattgtgacaaatttgaagtgaatacacagagcgtggcctacttagca gctttacttacagtgtctgaagaagttcgaagtcgctgcagcctaaaacatagaaagtca cttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccattcatcat ggtgaccctacctataggacactgaaggagactcagccatggtcctctcccaaaggttct gaaggataccttgcagccacctatccaactgtcggccagaccagtccccgagccaggaaa tccatgagcctggacatggggcagccttctcaagccaacactaagaagttgcttggaaca aggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaaatggaa tcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaaatggaa actcagaggatttcctcatcacaacagcacccacatttacgtaaggtttcagtgtctgaa tcaaatgttctcttggatgaagaagtacttactgatccgaagatccaggcgctgcttctt actgttctagctacactggtaaaatataccacagatgagtttgatcaacgaattctttat gaatacttagcagaggccagtgttgtgtttcccaaagtctttcctgttgtgcataatttg ttggactctaagatcaacaccctgttatcattgtgccaagatccaaatttgttaaatcca atccatggaattgtgcagagtgtggtgtaccacgaagaatccccaccacaataccaaaca tcttacctgcaaagttttggttttaatggcttgtggcggtttgcaggacccttttcaaag caaacacaaattccagactatgctgagcttattgttaagtttcttgatgccttgattgac acgtacctgcctggaattgatgaagaaaccagtgaggaatccctcctgacacccacatct ccttaccctcctgcactgcagagccagcttagtatcactgccaaccttaacctctctaat tccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagaacgttgaa ctctcccctaccactggccactgtaacagtggacgaactcgccacggatccgcaagccaa gtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcattaagaagatcgtgtga

DBGET integrated database retrieval system