Pongo abelii (Sumatran orangutan): 100440902
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Entry
100440902 CDS
T01416
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4A isoform X2
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00230
Purine metabolism
pon01100
Metabolic pathways
pon04024
cAMP signaling pathway
pon04928
Parathyroid hormone synthesis, secretion and action
pon05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100440902
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100440902
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100440902
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100440902
Enzymes [BR:
pon01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100440902
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
100440902
NCBI-ProteinID:
XP_024092633
Ensembl:
ENSPPYG00000009552
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Position
20:10467922..10507153
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AA seq
860 aa
AA seq
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MARPRGLGRIPELQLVAFPVAVAAEDEAFLPEPLAPRAPRRLCSPPSSPVFFASPSPTFR
RRLRLLRSFQDLGRQAWAGAGFEAENGPTPSPGRSTLDSQASPGLVLHAGAATSQRRESF
LYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPFAQVLASLRSVRSNFSLLTNVPVPSN
KRSPLGGPTPVCKATLSEETCQQLARETLEELDWCLEQLETMQTYRSVSEMASHKFKRML
NRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIPSPTMKEREKQQAPRPRPSQPPPPPV
PHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTDQEELLAQELENLNKWGLNIFCVSDYA
GGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLTLEDHYHVDVAYHNSLHAADVLQSTH
VLLATPALDAVFTDLEILAALFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVT
SSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLELYRQWTDRIMAEFFQQGDRERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVHPDAQEILDTLEDNRDWYYSAIRQS
PSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEEISMAQIPCTAQEALIAQGLSGVKEAL
DATMAREASPAQESLEVMAQEASLEAELEEVYLTQQAQPTGSAPVAQDDFSSQEESVVAV
SHSSPSALALQSPLLPAWRTLSGSEHAPGLPGLPSTAAEVEAQREHQAAKRACSACAGTF
GEDTSALPAPGGVGSGGDPT
NT seq
2583 nt
NT seq
+upstream
nt +downstream
nt
atggcgcggccgcgcggcctaggccgcatcccggagctgcaactggtggccttcccggtg
gcggtggcggctgaggacgaggcgttcctgcccgagcccctggccccgcgcgcgccccgc
cgcctgtgttcgccgccgtcctcgcccgtcttctttgccagcccgtccccaactttccgc
agacgccttcggcttctccgcagcttccaggatttgggccgccaggcgtgggctggggct
ggctttgaggcagagaatgggccgacaccatctcctggccgcagcaccctggactcgcag
gcgagtccaggactcgtgctgcacgctggggcggccaccagccagcgccgggagtccttc
ttgtaccgctcagacagcgactatgacatgtcacccaagaccatgtcccggaactcatcg
gtcaccagcgaggcgcacgctgaagacctcatcgtaacaccgtttgcccaggtgctggcc
agcctccggagcgtccgtagcaacttctcactcctgaccaatgtgcccgttcccagtaac
aagaggtccccgctgggcggccccacccctgtctgcaaggccacgctgtcagaagaaaca
tgtcagcagttggcccgggagactctggaggagctggactggtgtctggagcagctggag
accatgcagacctaccgctctgtcagcgagatggcctcgcacaagttcaagaggatgttg
aaccgtgagctcacacacctgtcagaaatgagcaggtccggaaaccaggtctcagagtac
atttccacaacattcctggacaaacagaatgaagtggagatcccatcacccacgatgaag
gaacgagaaaaacagcaagcaccgcgaccaagaccctcccagccacccccgccccctgta
ccacacttacagcccatgtcccaaatcacaggggtgaaaaagttgatgcatagtaacagc
ctgaacaactctaacattccccgatttggggtgaagactgatcaagaagagctcctggcc
caagaactggagaacctgaacaagtggggtctgaacatcttttgcgtgtcggattatgcc
ggaggccgctcgctcacctgcatcatgtacatgatattccaggagcgggacctgctgaag
aaattccgcatccctgtggacacgatggtgacatacatgctgacgctggaggatcactac
cacgtagacgtggcctaccataacagcctgcacgcagctgacgtgctgcagtccacccac
gtactgctggccacgcctgcgctagatgcagtgttcacggacctggagattctcgccgcc
ctcttcgcggctgccatccacgatgtggatcaccctggggtctccaaccagttcctcatc
aacaccaattcggagctggcgctcatgtacaacgatgagtcggtgctcgagaatcaccac
ctggccgtgggcttcaagctgctgcaggaggacaactgcgacatcttccagaacctcagc
aagcgccagcggcagagcctacgcaagatggtcatcgacatggtgctggccacggacatg
tccaagcacatgaccctcttggctgacctgaagaccatggtggagaccaagaaagtgacc
agctcaggggtcctcctgctggataactactccgaccgcatccaggtcctccggaacatg
gtgcactgtgcagacctcagcaaccccaccaagccgctggagctgtaccgccagtggaca
gaccgcatcatggctgagttcttccagcagggtgaccgtgagcgcgagcgtggcatggaa
atcagccccatgtgtgacaagcacactgcctccgtggagaagtctcaggtgggttttatt
gactacattgtgcacccattgtgggagacctgggcggaccttgtccacccagatgcccag
gagatcctggacactttggaggacaaccgggactggtactacagcgccatccggcagagc
ccgtctccaccacccgaggaggagtcaagggggccaggccacccacccccgcctgacaag
ttccagtttgagctgacgctggaggaggaagaagaggaagaaatatcaatggcccagata
ccatgcacagcccaagaggcattgatagcgcagggattgtcaggagtcaaggaagctctg
gatgcaaccatggcccgggaggcatccccggcccaggagtcattggaagttatggcacag
gaagcatccctggaggccgagctggaggaagtgtatttgacacagcaggcacagcccaca
ggcagtgcacctgtggctcaggatgacttctcgtcccaggaggaatccgtggttgctgta
agccacagcagcccctctgccctggctcttcaaagcccccttctccctgcctggaggacc
ctgtctggttcagagcatgccccgggcctcccgggcctcccctccacggcggccgaggtg
gaggcccaacgagagcaccaggctgccaagagggcttgcagtgcctgcgcagggacattt
ggggaggacacatccgcactcccagctcctggtggggtggggtcaggtggagaccctacc
tga
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