Pongo abelii (Sumatran orangutan): 100441126 Help Entry 100441126         CDS       T01416                                  Symbol TSC2 Name (RefSeq) tuberin isoform X6   KO K07207   tuberous sclerosis 2 Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon04072   Phospholipase D signaling pathway pon04115   p53 signaling pathway pon04140   Autophagy - animal pon04150   mTOR signaling pathway pon04151   PI3K-Akt signaling pathway pon04152   AMPK signaling pathway pon04211   Longevity regulating pathway pon04218   Cellular senescence pon04714   Thermogenesis pon04910   Insulin signaling pathway pon04919   Thyroid hormone signaling pathway pon05163   Human cytomegalovirus infection pon05165   Human papillomavirus infection pon05168   Herpes simplex virus 1 infection pon05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     100441126 (TSC2)    04151 PI3K-Akt signaling pathway     100441126 (TSC2)    04152 AMPK signaling pathway     100441126 (TSC2)    04150 mTOR signaling pathway     100441126 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     100441126 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     100441126 (TSC2)    04218 Cellular senescence     100441126 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     100441126 (TSC2)    04919 Thyroid hormone signaling pathway     100441126 (TSC2)   09149 Aging    04211 Longevity regulating pathway     100441126 (TSC2)   09159 Environmental adaptation    04714 Thermogenesis     100441126 (TSC2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     100441126 (TSC2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     100441126 (TSC2)    05163 Human cytomegalovirus infection     100441126 (TSC2)    05165 Human papillomavirus infection     100441126 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:pon01009]     100441126 (TSC2) Protein phosphatases and associated proteins [BR:pon01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      100441126 (TSC2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  100441126 NCBI-ProteinID:  XP_024089853 Ensembl:  ENSPPYG00000006986 LinkDB All DBs Position 18:2155683..2197767 Genome browser AA seq 1784 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRM IGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFI VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVG MALWGAHRLYSLRNSPTSVLPSFYQAMVCPNEVVSYEIVLSITRLIKKYRKELQVVTWDI LLNIIERLLQQLQTLDSPELRTVVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVAARSLS PPPELEERDAAAHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKH SYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTS GPLSPPSGPPGPAPAGPAVRLGSLPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYK VLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYL DKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMA VPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS PPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHL ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL LGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVG ALDMPASQFLGSATSPGPRTAPAAKPEKVSAGTRVPVQEKTNLAAYVPLLTQGWAEILVR RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAST ARPPPLPRSNTDSAAVVEEGSPGEVPVPVEPPGLEDFEAALGMDRRTDAYSRSSSVSSQE EKSLHAEELVARGIPIERAVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGD KADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTI SDSAPSRRGKRVERDAFKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNE SQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIE LKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDRHRCDKKRHLGN DFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIV SDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNP SLPLVHPPSHTKAPAQTPAEPTPGYEMGQRKRLVSSVEDFTEFV NT seq 5355 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattcaggcttgaaggagaagtttaagattctgttggga ctgggaacaccgaggccaaatcccaggtctgcagagggtaaacagacggagtttatcatc accgcggaaatactgagagaactgagcatggaatgtggcctcaacaatcgcatccggatg atagggcagatttgtgaagttgcaaaaaccaagaaatttgaagagcacgcagtggaagca ctttggaaggcggtcgcggatctgttgcagccggagcggccactggaggcccggcacgcg gtgctggctctgctgaaggccatcgtgcagggacagggcgagcgtttgggggtcctcaga gccctcttctttaaggtcatcaaggattacccttccaatgaagaccttcacgaaaggctg gaagttttcaaggccctcacagacaatgggagacacatcacctacttggaggaagagctg gctgactttgtcctgcagtggatggatgttggcttgtcctcggaattccttctggtgctg gtgaacttggtcaaattcaatagctgttacctcgacgagtacatcgcaaggatggttcag atgatctgtctgctctgcgtccggaccgcatcctctgtggacatagaggtctccctgcag gtgctggacgctgtggtctgctacaactgcctgccggctgagagcctcccgctgttcatc gttactctctgtcgcaccatcaacgtcaaggagctctgcgagccttgctggaagctgatg cggaacctccttggcacccacctgggccacagcgccatctataacatgtgccacctcatg gaggacagagcctacatggaggacgcgcccctgctgagaggagccgtgttttttgtgggc atggctctctggggagcccaccggctctattctctgaggaactcgccgacatctgtgcta ccatcattttaccaggccatggtatgtccgaacgaggtggtgtcctatgagatcgtcctg tccatcaccaggctcatcaagaagtacaggaaggagctccaggtggtgacgtgggacatt ctgctgaacatcatcgaacggctccttcagcagctccagaccttggacagcccggagctc aggaccgttgtccatgacctgttgaccacggtggaggagctgtgtgaccagaacgagttc cacgggtctcaggagagatactttgaactggtggagagatgtgcggaccagaggccggag tcctccctcctgaacctgatctcctatagagcgcagtccatccacccggccaaggacggc tggattcagaacctgcaggcgctgatggagagattcttcaggagcgagtcccgaggcgcc gtgcgcatcaaggtgctggacgtgctgtcctttgtgctgctcatcaacaggcagttctat gaggaggagctgattaactcagtggtcatctcgcagctctcccacatccccgaggataaa gaccaccaggtccgaaagctggccacccagttgctggtggacctggcagagggctgccac acacaccacttcaacagcctgctggacatcatcgagaaggtggcggcccgctccctctcc ccacccccagagctggaagaaagggatgcggccgcacactcagcctccttggaggatgtg aagacagctgtcctgggtcttctggtcatccttcagaccaagctgtacaccctgcctgca agccacgccacgcgcgtgtatgagatgctggtcagccacattcagctccactacaagcac agctacaccctgccaatcgcgagcagcatccggctgcaggcctttgacttcctgttgctg ctgcgggccgactcactgcaccgcctcggcctgcccaacaaggatggagtcgtgcggttc agcccctactgcgtctgcgactacatggagccagagagaggctctgagaagaagaccagc ggccccctttctcctccctcagggccgcctggcccggcgcctgcaggtcccgccgtgcgg ctgggttccctgccctactccctgctcttccgtgtcctgctgcagtgcttgaagcaggag tctgactggaaggtgctgaagctggttctgggcaggctgcccgagtccctgcgctacaaa gtgctcatctttacttccccttgcagtgtggaccagctgtgctctgctctctgctccatg ctttcaggcccaaagacactggagcggctccgaggcgccccagaaggcttctccagaact gacctgcacctggctgtggttccagtgctgacagcattaatctcttaccataactacctg gacaaaaccaaacagcgcgagatggtctactgcctggagcagggcctcatccaccgctgt gccagccagtgcgtcgtggccttgtccatctgcagcgtggagatgcctgacatcatcatc aaggcgctgcccgtcctggtggtgaagctcacacacatctcggccacagccagcatggcc gtcccactgctggagttcctgtccactctggccaggctgccgcacctctacaggaacttt gccgcggagcagtatgccagtgtgttcgccatctccctgccgtacaccaacccctccaag tttaatcagtacatcgtgtgtctggcccatcacgtcatagccatgtggttcatcaggtgc cgcctgcccttccggaaggatttcgtccctttcatcactaagggcctgcggtccaatgtc ctcttgtcttttgatgacacccccgagaaggacagcttcagggcccggagtactagtctc aacgagagacccaagagtctgaggatagccagaccccccaaacaaggcttgaataactct ccacccgtgaaagaattcaaggagagctctgcagccgaggccttccggtgccgcagcatc agtgtgtctgaacatgtggtccgcagcaggatacagacgtccctcaccagtgccagcttg gggtctgcagacgagaactccgtggcccaggctgacgatagcctgaaaaacctccacctg gagctcacggaaacctgtctggacatgatggctcgatacgtcttctccaacttcacggct gtcccgaagaggtctcctgtgggcgagttcctcctggcgggtggcaggaccaaaacctgg ctggttgggaacaagcttgtcactgtgacgacaagcgtgggaaccgggacccggtcgtta ctaggcctggactcgggggagttgcagtccggcccagagtcgagctccagccccggcgtg catgtgagacagacaaaggaggcgccggccaagctggagtcccaggctgggcagcaggtg tcccgtggggcccgggaccgggtccgttccatgtcggggggccatggtcttcgagttggc gccctggacatgccggcctcccagttcctgggcagtgccacttctccaggaccacggact gcaccagccgcgaagcctgagaaggtgtcagctggcacccgggttcctgtgcaggagaag acgaacttggcggcctacgtacccctgctgacccagggctgggcggagatcctggtccgg aggcccacagggaacaccagctggctgatgagcctggagaacccgctcagccctttctct tcggacatcaacaacatgcccctgcaggagctgtccaacgccctcatggcggctgagcgc ttcaaggagcaccgggacacagccctgtacaagtcattgtcggtgccggcggccagcacg gccagaccccctcctctgcctcgctccaacacagactccgctgcggtcgtggaggaggga agtcctggcgaggttcctgtgccagtggagcccccaggcttggaggactttgaggcagcg ctaggcatggacaggcgcacggatgcctacagcaggtcgtcctcagtctccagccaggag gagaagtcgctccacgcggaggagctggttgccaggggcatccccatcgagcgagccgtc tcctcggagggtggccggccctctgtggacctctccttccagccctcgcagcccctgagc aagtccagctcctctcccgagctgcagaccctgcaggacatcctcggggaccctggggac aaggccgacgtgggccggctgagccctgaggttaaggcccggtcacagtcagggaccctg gacggggaaagtgctgcctggtcagcctcgggcgaagacagtcggggccagccggagggt cccttgccttccagctccccccgctcgcccagtggcctccggccccgaggttacaccatc tccgactcggccccatcacggaggggcaagagggtagagagggatgcctttaagagcaga gccacagcctccaatgcagagaaagtgccgggcatcaaccccagtttcgtgttcctgcag ctctaccattcccccttctttggcgacgagtcaaacaagccaatcctgctgcccaatgag tcacagtcctttgagcggtcggtgcagctcctcgaccagatcccatcatacgacacccac aagatcgccgtcctgtatgttggagaaggccagagcaacagcgagctcgccatcctgtcc aacgagcatggctcctacaggtacacggagttcctgacgggcctgggccggctcatcgag ctgaaagactgccagcccgacaaggtgtacctgggaggcctggacgtgtgtggtgaggat ggccagttcacctactgctggcacgatgacatcatgcaagccgtcttccacatcgcgacc ctgatgcccaccaaggacgtggacaggcaccgctgcgacaagaagcgccacctgggcaat gactttgtgtccattgtctacaatgactccggcgaggactttaagctcggcaccatcaag ggccagttcaactttgtccacgtgatcgtcaccccgctggactatgagtgcaacctggtg tccctgcagtgcaggaaagacatggagggccttgtggacaccagcgtggccaagatcgtg tctgaccgcaacctgcccttcgtggcccgccagatggccctgcacgcaaatatggcctca caggtgcaccatagccgctccaaccccaccgacatctacccctccaagtggattgcccgg ctccgccacatcaagaggctccgccagcggatctgtgaggaagccgcctactccaacccc agcctgcctctggtgcaccccccgtcccataccaaagcccctgcacagactccagccgag cccacacctggctacgagatgggccagcggaagcgcctcgtctcctccgtggaggacttc accgagttcgtgtga

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