Pongo abelii (Sumatran orangutan): 100446409
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Entry
100446409 CDS
T01416
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X3
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04020
Calcium signaling pathway
pon04022
cGMP-PKG signaling pathway
pon04024
cAMP signaling pathway
pon04148
Efferocytosis
pon04260
Cardiac muscle contraction
pon04261
Adrenergic signaling in cardiomyocytes
pon04380
Osteoclast differentiation
pon04919
Thyroid hormone signaling pathway
pon04972
Pancreatic secretion
pon05010
Alzheimer disease
pon05017
Spinocerebellar ataxia
pon05022
Pathways of neurodegeneration - multiple diseases
pon05410
Hypertrophic cardiomyopathy
pon05412
Arrhythmogenic right ventricular cardiomyopathy
pon05414
Dilated cardiomyopathy
pon05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100446409 (ATP2A3)
04024 cAMP signaling pathway
100446409 (ATP2A3)
04022 cGMP-PKG signaling pathway
100446409 (ATP2A3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100446409 (ATP2A3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100446409 (ATP2A3)
09153 Circulatory system
04260 Cardiac muscle contraction
100446409 (ATP2A3)
04261 Adrenergic signaling in cardiomyocytes
100446409 (ATP2A3)
09154 Digestive system
04972 Pancreatic secretion
100446409 (ATP2A3)
09158 Development and regeneration
04380 Osteoclast differentiation
100446409 (ATP2A3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100446409 (ATP2A3)
05017 Spinocerebellar ataxia
100446409 (ATP2A3)
05022 Pathways of neurodegeneration - multiple diseases
100446409 (ATP2A3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100446409 (ATP2A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
100446409 (ATP2A3)
05414 Dilated cardiomyopathy
100446409 (ATP2A3)
05415 Diabetic cardiomyopathy
100446409 (ATP2A3)
Enzymes [BR:
pon01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100446409 (ATP2A3)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF3106
TNP-like_RNaseH_N
Motif
Other DBs
NCBI-GeneID:
100446409
NCBI-ProteinID:
XP_002826901
Ensembl:
ENSPPYG00000007826
UniProt:
A0A2J8SPE7
LinkDB
All DBs
Position
19:complement(3717099..3757715)
Genome browser
AA seq
1069 aa
AA seq
DB search
MEAAHLLPAADVLSHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRLDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNIASGKAVGVAVATGLHTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNAVIKQLMR
KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT
SREQILAKIRDWSSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML
DPPRPEVAACITRCHQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD
LSPEQQRHACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPHVNFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLAAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVVVLQISLPVILLDEALKYLSRNHMHACLYPGILGTVSQAWSRQPLTTSWTPD
HTGLASLGQGHSVVFLSELLREGRSRGELPFLGICAEAVAVWLDCCAGA
NT seq
3210 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgcacctgctcccggccgccgacgtgctgagccacttctcggtgacagcc
gagggcggcctgagtccggcgcaggtgaccggcgcgcgggagcgctacggccccaacgag
ctcccgagtgaggaagggaagtccctgtgggagctggtgctggaacagtttgaggacctc
ctggtgcgcatcctgctgctggccgcccttgtctcctttgtcctggcctggttcgaggag
ggcgaggagaccacgaccgccttcgtggagcccctggtcatcatgctgatcctcgtggcc
aacgccattgtgggcgtgtggcaggaacgcaacgccgagagtgccatcgaggccctgaag
gagtatgagcctgagatgggcaaggtgatccgcttggaccgcaagggcgtgcagaggatc
cgtgcccgggacattgtcccaggggacattgtagaggtggcagtgggggacaaagtacct
gctgacctccgcctcatcgagatcaaatccaccacgctgcgagtggaccagtccatcctg
acgggtgaatctgtgtccgtgaccaagcacacagaggccatcccagaccccagagctgtg
aaccaggacaagaagaatatgctgttttctggcaccaatatcgcatcgggcaaagcagtg
ggtgtggccgtggccaccggcctgcacacggagctgggcaagatccggagccagatggcg
gcagtggagcctgagcggacgccgctgcagcgcaaactggatgagtttggacggcagctg
tcccacgccatctctgtgatctgcgtggccgtgtgggtcatcaacatcggccacttcgcc
gacccagcccatggtggctcctggctgcgcggcgctgtctactacttcaagatcgccgtg
gccctggctgtggcggccatccccgagggcctcccggctgtcatcactacatgcctggca
ctgggcacgcggcgcatggcacgcaagaacgccatcgtgcgaagcctgccgtccgtggag
accctgggctgcacctcagtcatctgctccgacaagacaggcacactcaccaccaatcag
atgtctgtctgccggatgttcgtggtagccgaggccgatgcgggctcctgccttttgcac
gagttcaccatctcgggtaccacgtatacccccgagggcgaagtgcggcagggggatcag
cctgtgcgctgcggccagttcgacgggctggtggagctggcgaccatctgcgccctgtgc
aacgactcggcgctggactacaacgaggccaagggtgtgtatgagaaggtgggagaggcc
acggagacagctctgacttgcctggtggaaaagatgaacgtgttcgacaccgacctgcag
gccctgtcccgggtggagcgagctggcgcctgtaatgcggtcatcaagcagctgatgcgg
aaagagttcaccctggagttctcccgagaccggaagtccatgtccgtgtactgcacgccc
acccgccctcaccctactggccagggcagcaagatgtttgtgaagggggctcctgagagt
gtgattgagcgctgcagctcagtccgcgtggggagccgcacagcacccctgacccccacc
tccagggagcagatcctggcaaagatccgggattggagctcagggtcagacacgctgcgc
tgcctggcactggccacccgggacgcgcccccgaggaaggaggacatggagctggacgac
tgcagcaagtttgtgcagtacgagacggacctgaccttcgtgggctgcgtgggcatgctg
gacccgccgcgacctgaggtggctgcctgcatcacacgctgccaccaggcaggcatccgc
gtggtcatgatcacgggggataacaaaggcactgccgtggccatctgccgcaggcttggc
atctttggggacacggaagacgtggcgggcaaggcctacacgggccgcgagtttgatgac
ctcagccccgagcagcagcgccatgcctgccgcaccgcccgctgcttcgcccgcgtggag
cccgcacacaagtcccgcatcgtggagaacctgcagtcctttaacgagatcaccgccatg
actggtgatggagtgaacgacgcaccagccctgaagaaagcagagatcggcatcgccatg
ggctcgggcacggccgtggccaagtcggcggcagagatggtgctatcagatgacaacttt
gcctccatcgtggctgcggtggaggagggccgggccatctacagcaacatgaagcaattc
atccgctacctcatctcctccaatgttggcgaggtcgtctgcatcttcctcacggcaatt
ctgggcctgcccgaagccctgatccctgtgcagctgctctgggtgaacctggtgacagac
ggcctacctgccacagctctgggcttcaacccgccagacctggacatcatggagaagctg
ccccggagcccccgcgaagccctcatcagtggctggctcttctttcgatacctggctatc
ggagtgtacgtaggcctggccacagtggctgccgccacctggtggttcctgtatgatgcc
gagggacctcacgtcaacttctaccagctgaggaacttcctgaagtgctccgaagacaac
ccgctctttgccggcatcgactgtgaggtgttcgagtcgcgtttccccaccaccatggca
ttgtccgtgctcgtgaccattgaaatgtgcaatgctctcaacagcgtctcagagaaccag
tcgctgctgcggatgccgccctggatgaacccctggctgctggcagctgtggccatgtcc
atggccctgcacttcctcatcctgctcgtgccgcccctgcctctcattttccaggtgacc
ccactgagcgggcgccagtgggtggtggtgctccagatatctctgcctgtcatcctgctg
gatgaggccctcaagtacctgtcccggaaccacatgcacgcctgtctttatccaggcatt
ctcgggacagtctcgcaggcctggagtaggcagccgctgaccacctcttggaccccagac
cacaccgggttggcctctttgggccagggacacagcgtcgtcttcctgtcagagctgctc
agagagggaagaagcaggggtgagctcccgttcctgggaatttgcgcagaggcagtggct
gtatggctggactgctgtgcaggggcctag
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