Pongo abelii (Sumatran orangutan): 100446505
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Entry
100446505 CDS
T01416
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X3
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00230
Purine metabolism
pon01100
Metabolic pathways
pon04022
cGMP-PKG signaling pathway
pon04740
Olfactory transduction
pon04925
Aldosterone synthesis and secretion
pon05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100446505 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
100446505 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
100446505 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
100446505 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100446505 (PDE2A)
Enzymes [BR:
pon01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100446505 (PDE2A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
100446505
NCBI-ProteinID:
XP_024111136
Ensembl:
ENSPPYG00000003652
UniProt:
A0A2J8V1U2
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All DBs
Position
9:complement(74613468..74713359)
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AA seq
920 aa
AA seq
DB search
MRRQPAASLDPLAKEPGPPGSRDDRLEDALLSLGSVIDISGLQRAVKEALSAVLPRVETV
YTYLLDGESRLVCEDPPHELPQEGKVREAIICRKRLGCNGLGFSDLPGKPLARLVAPLAP
DTQVLVMPLVDKEAGAVAAVILVHCGQLRDSEEWSLQAVEKHTLVALRRVQALQQRGPRE
APRAVQNPPEGAAEDQKGGAAYTDRDRKILQLCGELYDLDASSLQLKVLQYLQQETRASR
CCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTGCLGQVVEDKKSIQLKDLTSEDVQQLQS
MLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTDEDEQVIQHCFHYTSTVLTSTL
AFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELV
AKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRN
ILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQ
YRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFASFTYTPRSLPEDDTSMAILS
MLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELTNYL
EDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTH
GCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAQVGYDRNNKQHHRLLLC
LLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQIS
FMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYE
VPDLDGTRAPINGCCSLDAE
NT seq
2763 nt
NT seq
+upstream
nt +downstream
nt
atgcgccgacagcctgcagccagcctggacccccttgcaaaggagccaggacccccaggg
agtagagacgaccgactggaggacgctttgctgagtctgggctctgtcatcgacatttca
ggcctgcaacgtgctgtcaaggaggccctgtcagctgtgctcccccgagtggaaactgtc
tacacctacctgctggatggggagtcccggctggtgtgtgaggaccccccacatgagctg
ccccaggaggggaaagtccgggaggctatcatctgccggaagcggctgggctgcaatggg
ctgggcttctcagacctgccagggaagcccttggccaggctggtggctccactggctcct
gatacccaagtgctggtcatgccgctagtggacaaggaggccggggccgtggcagctgtc
atcttggtgcactgtggccagctgcgtgacagtgaggaatggagcctgcaggcagtggag
aagcataccctggtggccctgaggagggtgcaggccctgcagcagcgcgggcccagggag
gctccccgagcggtccagaaccccccggagggggcggcggaagaccagaagggcggggcg
gcgtacaccgaccgcgaccgcaagatcctgcaactgtgcggggaactctacgacctggat
gcctcttccctgcagctcaaagtgctccaatacctgcagcaggagacccgggcatcccgc
tgctgcctcctgctggtgtcggaggacaatctccagctttcttgcaaggtcatcggagac
aaagtgctcggagaagaggtcagctttcccttgacaggatgcctgggccaggtggtggaa
gacaagaagtccatccagctgaaagacctcacctctgaggatgtacaacagctgcagagc
atgttgggctgtgagctgcaggccatgctctgtgtccctgtcatcagccgggccactgac
caggtggtggccttggcctgcgccttcaacaagctagaaggagacttgttcaccgacgag
gacgagcaggtgatccagcactgcttccactacaccagcaccgtgctcaccagcaccctg
gccttccagaaggaacagaaactcaagtgtgagtgccaggctcttctccaagtggcaaag
aacctcttcacccacctggatgacgtctctgtcctgctccaggagatcatcacggaggcc
agaaacctcagcaacgcagagatctgctctgtgttcctgctggatcagaatgagctggtg
gccaaggtgttcgacgggggcgtggtggatgatgagagctatgagatccgcatcccggcc
gatcagggcatcgcgggacacgtggcgaccacgggccagatcctgaacatccctgacgca
tatgcccatccgcttttctaccgcggcgtggacgacagcaccggcttccgcacgcgcaac
atcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgagctggtg
aacaagatcaatgggccgtggttcagcaagttcgacgaggacctggcgacggccttctcc
atctactgcggcatcagcatcgcccattctctcctatacaaaaaagtgaatgaggctcag
tatcgcagccacctggccaatgagatgatgatgtaccacatgaaggtctccgacgatgag
tataccaaacttctccatgatgggatccagcctgtggctgccattgactccaattttgca
agtttcacctatacccctcgttccctgccagaggatgacacgtccatggccatcctgagc
atgctgcaggacatgaatttcatcaacaactacaaaattgactgcccgaccctggcccgg
ttctgtttgatggtgaagaagggctaccgggatcccccctaccacaactggatgcacgcc
ttttctgtctcccacttctgctacctgctctacaagaacctggagctcaccaactacctc
gaggacatcgagatctttgccttgtttatttcctgcatgtgtcatgacctggaccacaga
ggcacaaacaactctttccaggtggcctcgaaatctgtgctggctgcgctctacagctct
gagggctccgtcatggagaggcaccactttgctcaggccatcgccatcctcaacacccac
ggctgcaacatctttgatcatttctcccggaaggactatcagcgcatgctggatctgatg
cgggacatcatcttggccacagacctggcccaccatctccgcatcttcaaggacctccag
aagatggctcaggtgggctatgaccgaaacaacaagcagcaccacagactcctcctctgc
ctcctcatgacctcctgtgacctctctgaccagaccaagggctggaagaccacgagaaag
atcgcggagctgatctacaaagaattcttctcccagggagacctggagaaggccatgggc
aacaggccgatggagatgatggaccgggagaaggcctatatccctgagctgcaaatcagc
ttcatggagcacattgcaatgcccatctacaagctgttgcaggacctgttccccaaagca
gcagagctgtacgagcgcgtggcctccaaccgtgagcactggaccaaggtgtcccacaag
ttcaccatccgcggcctcccaagtaacaactcgctggacttcctggatgaggagtacgag
gtgcctgatctggatggcactagggcccccatcaatggctgctgcagccttgatgctgag
tga
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