Pongo abelii (Sumatran orangutan): 100446745
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Entry
100446745 CDS
T01416
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00230
Purine metabolism
pon01100
Metabolic pathways
pon04022
cGMP-PKG signaling pathway
pon04024
cAMP signaling pathway
pon04924
Renin secretion
pon05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100446745 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100446745 (PDE3A)
04022 cGMP-PKG signaling pathway
100446745 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100446745 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100446745 (PDE3A)
Enzymes [BR:
pon01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100446745 (PDE3A)
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GFIT
Motif
Pfam:
PDEase_I
TgpA_N
EST1
Motif
Other DBs
NCBI-GeneID:
100446745
NCBI-ProteinID:
XP_024113065
Ensembl:
ENSPPYG00000004346
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Position
10:21104736..21408631
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AA seq
1142 aa
AA seq
DB search
MAVPSDAARVRDKPVHSGVSQAPTAGRDCHHRADPASPRDSGCRGCWGDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEVGCDLEQCKEAAAAAEEEEAAPGAEGGVFPGPRGGA
PGGGARLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLG
VGEDHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVAWRPY
LAYLAGVLGILLARYVEQILPQSAEAAPREHWGSQLIAGTKEDIPVFKRRRRSSSVVSAE
MSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITD
LLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVTSLSENYTCSDSEESSEKDKL
AIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSTSIKLQEAPSSSPDSW
NNPVMMTLTKSRSFTSSYAISAANHVKAKKQSRPGALAKISPLSSPCSSPLQGTPASSLV
SKISAVQFPESADTTAKQSLGSHRALTYTQSAPDLSPQILTPPVICSSCGRPYSQGNPAD
ESLERSGVATRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDEAECLREPLRKASACSTY
APETIMFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLF
EDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTVI
NDHGSTSDSDSDSGFTHGHMGYVFSKTYNVTDDKYGCLSGNIPALELMALYVAAAMHDYD
HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRF
LVIEAILATDLKKHFDFVAKFNGKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKE
LHLQWTDGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSA
GLMPGKWVEDSDESGDTDDPEEEEEEAVAPNEEETCENNESPKKKTFKRRKIYCQITQHL
LQNHKMWKKVIEEEQRLVGIENQSLDQTPQSHSSEQIQAIKEEEEEKGKPRGEEIPIQKP
DQ
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgcccagcgacgctgcacgagtcagggacaagcccgtccacagtggggtgagt
caagcccccacggcgggccgggactgccaccatcgtgcggaccccgcatcgccgcgggac
tcgggctgccgtggctgctggggagacctggtgctgcagccgctccggcgctctcggaaa
ctttcctccgcgctgtgcgcgggctccctgtcctttctgctggcgctgctggtgaggctg
gtccgcggggaggtcggatgtgacctggagcagtgtaaggaggcggcggcggcggcggag
gaggaggaagcagccccgggagcagaagggggcgtcttcccggggcctcggggaggtgct
cccgggggcggtgcgcggctcagcccctggctgcagccctcggcgctgctcttcagtctc
ctgtgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctg
gctgtcgcgctgctggccgcctgctgcgggggggaagcgctcgtccagattgggctgggc
gtcggggaggatcacttactctcactccccgccgcgggggtggtgctcagctgcttggcc
gccgcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagc
gcggtcaggaccgtgtccctcatttccttagagaggttcaaggtcgcctggagaccttac
ctggcgtacttggccggcgtgctggggatcctcttggccaggtacgtggaacaaatcttg
ccgcagtccgcggaggcggctccaagggagcactgggggtcccagctgattgctgggacc
aaggaagatatcccggtgtttaagaggaggaggcggtccagctccgtcgtgtccgccgag
atgtccggctgcagcagcaagtcccatcggaggacctccctgccctgtataccgagggaa
cagctcatggggcattcagaatgggaccacaaacgagggccaagaggatcacagtcttca
ggaaccagtattactgtggacattgccgtcatgggcgaggcccacggcctcattaccgac
ctcctggcagacccttctcttccaccaaacgtgtgcacatccttgagagccgtgagcaac
ttgctcagcacacagctcaccttccaggccattcacaagcccagagtgaatcccgtcact
tcgctcagtgaaaactatacctgttctgactctgaagagagctctgaaaaagacaagctt
gctattccaaagcgcctgagaaggagtttgccccctggcttgttgagacgagtttcttcc
acttggaccaccaccacctcggccacaggtctacccaccttggagcctgcaccagtacgg
agagaccgcagcaccagcatcaaactgcaggaagcaccttcatccagtcctgattcttgg
aataatccagtgatgatgaccctcaccaaaagcagatcctttacttcatcctatgctatt
tctgcagctaaccatgtaaaggctaaaaagcaaagtcgaccaggtgccctcgctaaaatt
tcacctctttcatcgccctgctcctcacctctccaagggactcctgccagcagcctggtc
agcaaaatttctgcagtgcagtttccagaatctgctgacacaactgccaaacaaagccta
ggttctcacagggccttaacttacactcagagtgccccagacctatcccctcaaatcctg
actccacctgttatatgtagcagctgtggcagaccatattcccaagggaatcctgctgat
gagtccctggagagaagtggggtagccactcggacaccaagtagaacagatgacactgct
caagttacctctgattatgaaaccaataacaacagtgacagcagtgacattgtacagaat
gaagatgaagcagagtgcctgagagagcctctgaggaaagcatcggcttgcagcacctat
gctcctgagaccattatgtttctggacaaaccaattcttgctcccgaacctcttgtcatg
gataacctggactccattatggagcagctaaatacttggaattttccaatttttgattta
gtggaaaatataggaagaaaatgtggccgtattcttagtcaggtatcttacagacttttt
gaagacatgggcctctttgaagcttttaaaattccaattagggaatttatgaattatttt
catgctttggagattggatatagggatattccttatcataacagaatccatgccactgat
gttttacatgctgtttggtatcttactacacagcctattccaggcctctcaactgtgatt
aatgatcatggttcaaccagtgattcagattctgacagtggatttacacatggacatatg
ggatacgtattctcaaaaacgtataatgtgacagatgataaatacggatgtctgtctggg
aatatccctgccttagagttgatggcgctgtatgtggctgcagccatgcacgattatgat
cacccaggaaggactaatgctttcctggttgcaactagtgctcctcaggcggtgctatat
aacgatcgttcagttttggagaatcatcacgcagctgctgcatggaatcttttcatgtcc
cggccagagtataacttcttagttaaccttgaccatgtggaatttaagcatttccgtttc
cttgtcattgaagcaattttggccactgacctgaagaaacactttgacttcgtagccaaa
tttaatggcaaggtaaatgatgatgttggaatagattggaccaatgaaaatgatcgtcta
ctggtttgtcaaatgtgtataaagttggctgatatcaatggtccagctaaatgtaaagaa
ctccatcttcagtggacagatggtattgtcaatgaattttatgaacagggtgatgaagag
gccagccttggattacccataagccccttcatggatcgttctgctcctcagctggccaac
cttcaggaatccttcatctctcacattgtggggcctctgtgcaactcctatgattcagca
ggactaatgccaggaaaatgggtggaagacagcgatgagtcaggagatactgatgaccca
gaagaagaggaggaagaagcagtagcaccaaatgaagaggaaacctgtgaaaataatgaa
tctccaaaaaagaagactttcaaaaggagaaaaatctactgccaaataactcagcacctc
ttacagaaccacaagatgtggaagaaagtcattgaagaggagcaacggctggtgggcata
gaaaatcaatccctggaccagacacctcagtcgcactcttcagaacagatccaggctatc
aaggaagaagaagaagagaaagggaaaccaagaggggaggagataccaatccaaaagcca
gaccagtga
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