Pongo abelii (Sumatran orangutan): 100450868
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Entry
100450868 CDS
T01416
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform X1
KO
K04849
voltage-dependent calcium channel N type alpha-1B
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon04010
MAPK signaling pathway
pon04020
Calcium signaling pathway
pon04721
Synaptic vesicle cycle
pon04723
Retrograde endocannabinoid signaling
pon04725
Cholinergic synapse
pon04726
Serotonergic synapse
pon04727
GABAergic synapse
pon04728
Dopaminergic synapse
pon04930
Type II diabetes mellitus
pon05016
Huntington disease
pon05020
Prion disease
pon05022
Pathways of neurodegeneration - multiple diseases
pon05032
Morphine addiction
pon05033
Nicotine addiction
pon05207
Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100450868 (CACNA1B)
04020 Calcium signaling pathway
100450868 (CACNA1B)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
100450868 (CACNA1B)
04725 Cholinergic synapse
100450868 (CACNA1B)
04728 Dopaminergic synapse
100450868 (CACNA1B)
04726 Serotonergic synapse
100450868 (CACNA1B)
04723 Retrograde endocannabinoid signaling
100450868 (CACNA1B)
04721 Synaptic vesicle cycle
100450868 (CACNA1B)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100450868 (CACNA1B)
09164 Neurodegenerative disease
05016 Huntington disease
100450868 (CACNA1B)
05020 Prion disease
100450868 (CACNA1B)
05022 Pathways of neurodegeneration - multiple diseases
100450868 (CACNA1B)
09165 Substance dependence
05032 Morphine addiction
100450868 (CACNA1B)
05033 Nicotine addiction
100450868 (CACNA1B)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100450868 (CACNA1B)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pon04040
]
100450868 (CACNA1B)
Ion channels [BR:
pon04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100450868 (CACNA1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Phage_TAC_15
Motif
Other DBs
NCBI-GeneID:
100450868
NCBI-ProteinID:
XP_054376903
Ensembl:
ENSPPYG00000019840
LinkDB
All DBs
Position
13:129291571..129538762
Genome browser
AA seq
2332 aa
AA seq
DB search
MVRFGDELGGRYGGPSGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNI
LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDAVLKRA
ATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMV
KAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTALYFAEFVFLGLFLTEMSLKMYGLGPR
SYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLV
VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQN
LRASCEALYSEMDPEERLRFATTCHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAA
EAPEGVDPPRRHHRHRDKDKTPAAGDQARAEAPKAESGEPGAREERPRPHRSHSKEAAGP
PEGRSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHR
GGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKEATEKEAEIVEADKEKELRNHQPRE
PHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQSPDLNTVVHIPVML
TGPPGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCH
YIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMID
LGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKR
LPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRG
QYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGP
SPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAI
SAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLK
CLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIANNFINLSF
LRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIAL
DDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYF
YFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISY
NDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIK
LAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQ
NKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAI
QNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGQSGALAVDVQMQSITRRGPD
GEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQ
APHHHHHRCHRRRDRKQRSLEKGPSLSADTDGAPSSAAGPGLPPGEGPTGCRRERERRQE
RGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGSHPQGSGS
VNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGR
LSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATN
SGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC
NT seq
6999 nt
NT seq
+upstream
nt +downstream
nt
atggtccgcttcggggacgagctgggcggccgctatgggggccccagcggcggggagcgg
gcccggggcggcggggccggcggggcggggggcccgggccccggggggctgcagcccggc
cagcgggtcctctacaagcaatcgatcgcgcagcgcgcgcggaccatggcgctgtacaac
cccatcccggtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgag
gacaacgtcgtccgcaaatacgcgaagcgcatcaccgagtggcctccgttcgagtacatg
atcctggccaccataatcgccaactgcatcgtgctggccctggagcagcacctccctgat
ggggacaaaacgcccatgtctgagcggctggacgacacggagccctatttcatcgggatc
ttttgcttcgaggcagggatcaaaatcatcgctctgggctttgtcttccacaagggctct
tacctgcggaatggatggaacgtcatggacttcgtggttgtcctcacagggatccttgcc
acggctggaactgacttcgacctgcgaacactgagggctgtgcgtgtgctgaggcccctg
aagctggtgtctgggattccaagtttgcaggtggtgctcaagtccatcatgaaggccatg
gttccactcctgcagatcgggctgcttctcttctttgccatcctcatgtttgccatcatt
ggcctggagttctacatgggcaagttccacaaggcctgtttccccaacagcacagatgca
gagcccgtgggtgacttcccctgtggcaaggaggccccagcccggctgtgcgagggcgac
actgagtgccgggagtactggccaggacccaacttcggcatcaccaactttgacaatatc
ctgtttgccatcttgacggtgttccagtgcatcaccatggagggctggactgacatcctc
tacaatacaaacgatgcggccggcaacacctggaactggctctacttcatccctctcatc
atcatcggctccttcttcatgctcaacctggtgctgggcgtgctttcgggggagtttgcc
aaggagcgagagagggtggagaaccgccgcgccttcctgaagctgcgccggcagcagcag
atcgagcgagagctcaacgggtacctggagtggatcttcaaggcggaggaagtcatgctg
gctgaggaagacaggaatgcagaggagaagtcccctttggacgcagtgctgaagagagcg
gctaccaagaagagcagaaatgacctgatccacgcagaggagggagaggaccggtttgca
gatctctgtgctgttggatcccccttcgcccgcgccagcctcaagagcgggaagacagag
agctcatcatacttccggaggaaggagaagatgttccggttttttatccggcgcatggtg
aaggctcagagcttctactgggtggtgctgtgcgtggtggccctgaacacgctgtgtgtg
gccatggtgcattacaaccagccgcggcggctcaccacggcgctgtattttgcagagttt
gttttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggcccaga
agctacttccggtcctccttcaactgcttcgactttggggtcatcgtggggagtgtcttt
gaagtggtctgggcggccatcaagccgggaagctcctttgggatcagcgtgctgcgggcc
ctccgcctgctgaggatcttcaaagtcacgaagtactggagctccctgcggaacctggtg
gtgtccctgctgaactccatgaagtccatcatcagcctgctcttcttgctcttcctgttc
attgtggtcttcgccctgctggggatgcagctgtttgggggacagttcaacttccaggat
gagactcccacaaccaacttcgacaccttccctgccgccatcctcactgtcttccagatc
ctgacgggagaggactggaacgcagtgatgtatcacgggatcgaatcacaaggcggcgtc
agcaaaggcatgttctcgtccttttacttcattgtcctgacgctgttcggaaactacact
ctgctgaatgtctttctggccattgctgtggacaacctggccaacgcccaagagctgacc
aaggatgaagaggagatggaagaagcagccaatcagaagctagctctgcaaaaagccaaa
gaagtggctgaagtcagccccatgtctgccgcgaacatctccatcgctgccaggcagcag
aactcggccaaggcgcgctcggtgtgggagcagcgggccagccagctacggctgcagaac
ctgcgggccagctgcgaggcgctgtacagcgagatggaccccgaggagcggctgcgcttc
gccactacgtgccatctgcggcccgacatgaagacgcacctggaccggccgctggtggtg
gagctgggccgcgacggcgcgcgggggcccgtgggaggcaaggcccgacctgaggctgcg
gaggcccccgagggcgtcgaccctccgcgcaggcaccaccggcaccgcgacaaggacaag
acccccgcggcgggggaccaggcccgagcagaggccccgaaggcggagagcggggagccc
ggtgcccgggaggagcggccgcggccgcaccgcagccacagcaaggaggccgcggggccc
ccggaggggcggagcgagcgcggccgaggcccaggccccgagggcggccggcggcaccac
cggcgcggctcccccgaggaggcggccgagcgggagccccgacgccaccgcgcgcaccgg
caccaggatccgagcaaggagtgcgccggggccaagggcgagcggcgcgcgcggcaccgc
ggcggcccccgagcggggccccgggaggcggagagcggggaggagccggcgcggcggcac
cgggcccggcacaaggcgcagcctgcacacgaggctgtagagaaggaagccacggagaag
gaggctgagatagtggaagccgacaaggagaaggagctccggaaccaccagcccagggag
ccacactgtgacctggagaccagtgggactgtgactgtgggccctatgcacacactgccc
agcacctgtctccagaaggtggaggaacagccagaggatgcagacaatcagcggaacgtc
actcgcatgggcagtcagtccccagacctgaacactgttgtacacatcccagtgatgctg
acgggccctcctggggaagccacagtcgttcccagtggtaacgtggacctggaaagccaa
gcagaggggaagaaggaggtggaagcagatgacgtgatgaggagcggcccccggcccatc
gtcccgtacagctccatgttctgtttaagccccaccaacctgctccgccgcttctgccac
tacatcgtgaccatgaggtacttcgagatggtcattctcgtggtcatcgccttgagcagc
atcgctctggctgctgaggacccagtgcgcacagactcgcccaggaacaatgctctgaaa
tacctggattacattttcactggtgtctttacctttgagatggtgataaagatgatcgac
ttgggactgctgcttcaccctggggcctatttccgggacttgtggaacattctggacttc
attgtggtcagtggcgccctggtggcgtttgctttctcaggatccaaagggaaagacatc
aataccatcaagtctctgagagtccttcgtgtcctgcggcccctcaagaccatcaaacgg
ctgcccaagctcaaggctgtgtttgactgtgtggtgaactccctgaagaatgtcctcaac
atcttgattgtctacatgctcttcatgttcatatttgccgtcattgcggtgcagctcttc
aaagggaagtttttctactgcacagatgaatccaaggagctggagagggactgcaggggt
cagtatttggattatgagaaggaggaagtggaagctcagcccaggcagtggaagaaatac
gactttcactacgacaatgtgctctgggctctactgacactgttcacagtgtccacgggg
gaaggctggcccatggtgctgaaacactctgtggatgccacctatgaggagcaggggccg
agccctgggtaccgcatggagctgtccatcttctacgtggtctactttgtggtgtttccc
ttcttcttcgtcaacatctttgtggccttgatcatcatcaccttccaggagcagggggac
aaggtgatgtctgaatgcagcctggagaagaatgagagggcttgcattgacttcgccatc
agcgccaaacccctgacacggtacatgccccaaaacaggcagtcgttccagtataagacg
tggacatttgtggtctccccgccctttgagtacttcatcatggccatgatagccctcaac
accgtggtgctgatgatgaagttctatgatgcaccctatgagtacgagctgatgctgaaa
tgcctgaacatcgtgttcacatccatgttctccatggaatgcgtgctgaagattatcgcc
tttggggtgctgaactatttcagagatgcctggaatgtctttgactttgtcactgtgttg
ggaagtattactgatattttagtaacagagattgcgaacaatttcatcaacctcagcttc
ctccgcctcttccgagccgcgcggctgatcaagctgctccgccagggctacaccatccgc
attctgctgtggacctttgtccagtccttcaaggccctgccctacgtgtgtctgctcatt
gccatgctgttcttcatctacgccatcatcggcatgcaggtgtttgggaatattgccctg
gatgatgacaccagcatcaaccgtcacaacaacttccggacgtttttgcaagccctgatg
ctgctgttcaggagcgccacgggggaggcctggcacgagatcatgctgtcctgcctgagc
aaccaggcctgtgatgagcaggccaatgccaccgagtgtggaagcgactttgcctacttc
tacttcgtctccttcatcttcctgtgctcctttctgatgttgaacctctttgtggctgtg
atcatggacaattttgagtaccttacgcgggactcttccatcctaggtcctcaccacttg
gacgagttcatccgggtctgggctgaatacgacccggccgcgtgtgggcgcatcagttac
aatgacatgtttgagatgctgaaacacatgtccccgcctctggggctggggaagaaatgc
cctgctcgagttgcttacaagcgcctggttcgcatgaacatgcccatctccaacgaggac
atgactgtccatttcacgtccacgctgatggccctcatccggacggcactggagatcaag
ttggcaccagctgggacaaagcagcatcagtgtgacgcagagttgaggaaggagatttcc
gttgtgtgggccaatctgccccagaagactttggacttgctggtaccaccccataagcct
gatgagatgacagtggggaaggtttatgcagctctgatgatattcgacttctacaagcag
aacaaaaccaccagagaccagatgcagcaggctcctggaggcctctcccagatgggtcct
gtgtccctgttccaccctctgaaggccaccctggagcagacacagccggctgtgctccga
ggagcccgggttttccttcgacagaagagttccacctccctcagcaatggcggggccata
caaaaccaagagagtggcatcaaggagtctgtctcctggggcactcaaaggacccaggat
gcaccccacgaggccaggccacccctggagcgtggccactccacagagatccctgtgggg
cagtcaggagcactggctgtggacgttcagatgcagagcataacccggaggggccctgat
ggggagccccagcctgggctggagagccagggtcgagcagcctccatgccccgccttgcg
gccgagactcagcccgtcacagatgccagccccatgaagcgctccatctccacgctggcc
cagcggccccgtgggactcatctttgcagcaccaccccggaccgcccaccccctagccag
gcgccgcaccaccaccaccaccgctgccaccgccgcagggacaggaagcagaggtccctg
gagaaggggcccagcctgtctgccgatacggatggcgcaccaagcagtgctgcggggccg
gggctgcccccgggagaggggcctacaggctgccggcgggaacgagagcgccggcaggag
aggggccggtcccaggagcggaggcagccctcatcctcctcctcggagaagcagcgcttt
tactcctgcgaccgcttcgggggccgtgagcccccaaagcccaagccctccctcagcagc
caccccacgtcgccaacagctggccaggagccaggatcccacccacagggcagtggttcc
gtgaatgggagccccttgctgtcaacatctggtgctagcacccccggccgcggcgggcgg
agacagctcccccagacgcccctgactccccgccccagcattacctacaagacggctaat
tcctcacccatccacttcgccggggctcagaccagcctccctgccttctccccgggccgc
ctcagccgtgggctttccgaacacaacgccctgctgcagagagaccccctcagccagccc
ctggcccctggctctcgaattggctctgacccttacctggggcagcgtctggacagtgag
gcctctgtccatgccctgcctgaggacacgctcactttcgaggaggctgtggccaccaac
tcgggccgctcctccaggacttcctacgtgtcctccctgacctcccagtctcaccctctc
cgccgcgtgcccaacggttaccactgcaccctgggactcagctcgggtggccgagcacgg
cacagctaccaccaccctgaccaggaccactggtgctag
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integrated database retrieval system
