| Entry |
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| Symbol |
LRP6
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| Name |
(RefSeq) low-density lipoprotein receptor-related protein 6 isoform X5
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| KO |
| K03068 | low density lipoprotein receptor-related protein 5/6 |
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| Organism |
pon Pongo abelii (Sumatran orangutan)
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| Pathway |
| pon04928 | Parathyroid hormone synthesis, secretion and action |
| pon05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:pon00001]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
100452008 (LRP6)
04150 mTOR signaling pathway
100452008 (LRP6)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100452008 (LRP6)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100452008 (LRP6)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
100452008 (LRP6)
05226 Gastric cancer
100452008 (LRP6)
05224 Breast cancer
100452008 (LRP6)
09164 Neurodegenerative disease
05010 Alzheimer disease
100452008 (LRP6)
05022 Pathways of neurodegeneration - multiple diseases
100452008 (LRP6)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:pon04131]
100452008 (LRP6)
Membrane trafficking [BR:pon04131]
Endocytosis
Clathrin-mediated endocytosis
Low-density lipoprotein receptor (LDLR) family proteins
100452008 (LRP6)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
10:complement(12762777..12914835)
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| AA seq |
1462 aa
MYWTDWGEVPKIERAGMDGSSRFIIINSEIYWPNGLTLDYEEQKLYWADAKLNFIHKSNL
DGTNRQAVVKGSLPHPFALTLFEDILYWTDWSTHSILACNKYTGEGLREIHSNIFSPMDI
HAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLLENGKTCKDGATELL
LLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDG
SGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAI
VLDPMVGYMYWTDWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGKIYWGDAKT
DKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQ
LPDLMGLKATNVHRVIGSNPCAEENGGCSHLCLYRPQGLRCACPIGFELISDMKTCIVPE
AFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFM
NGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPR
ALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLD
TNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQG
HLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSA
PTTFLLFSQKSAVNRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRK
AQEDGSQGFTVVVSSVPSQNLEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVV
LKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDS
RLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKID
MTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCP
MHLVLLQDELSCGEPPTCSPQQFTCFTGEIDCIPVAWRCDGFTECEDHSDELNCPVCSES
QFQCASGQCIDGAFRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCIGKHKKCDHNVDC
SDKSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTN
DYVVHGPASVPLGYVPHPGSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSS
SSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTP
CSTDVCDSDYAPSRRMTSVATAKGYTSDLNYDSEPVPPPPTPRSQYLSAEENYESCPPSP
YTERSYSHHLYPPPPSPCTDSS |
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| NT seq |
4389 nt +upstreamnt +downstreamnt
atgtactggacagactggggagaagtgccaaagatagaacgtgctggaatggatggttca
agtcgcttcattataataaacagtgaaatttactggccaaatggactgactttggattat
gaagaacaaaagctttattgggcagatgcaaaacttaatttcatccacaaatcaaatctg
gatggaacaaatcggcaggcagtggttaaaggttcccttccacatccttttgccttgacg
ttatttgaggacatattatactggactgactggagcacacactccattttggcttgcaac
aagtatactggtgagggtctgcgtgaaatccattctaacatcttctctcccatggatata
catgccttcagccaacagaggcagccaaatgccacaaatccatgtggaattgacaatggg
ggttgttcccatttgtgtttgatgtctccagtcaagcctttttatcagtgtgcttgcccc
actggggtcaaactcctggagaatggaaaaacctgcaaagatggtgccacagaattattg
cttttagctcgaaggacagacttgagacgcatttctttggatacaccagattttacagac
attgttctgcagttagaagacatccgtcatgccattgccatagattacgatcctgtggaa
ggctacatctactggactgatgatgaagtgagggccatacgccgttcatttatagatgga
tctggcagtcagtttgtggtcactgctcaaattgcccatcctgatggtattgctgtggac
tgggttgcacgaaatctttattggaccgacactggcactgatcgaatagaagtgacaagg
ctcaatgggaccatgaggaagatcttgatttcagaggacttagaggaaccccgggctatt
gtgttagatcccatggttgggtacatgtattggactgactggggagaaattccgaaaatt
gagcgagcagctctggatggttctgaccgtgtagtattggttaacacttctcttggttgg
ccaaatggtttagccttggattatgatgaaggcaaaatatactggggagatgccaaaaca
gacaagattgaggttatgaatactgatggcactgggagacgagtactagtggaagacaaa
attcctcacatatttggatttactttgttgggtgactatgtttactggactgactggcag
aggcgtagcattgaaagagttcataaacgaagtgcagagagggaagtgatcatagatcag
ctgcctgacctcatgggcctaaaagccacaaatgttcatcgagtgattggttccaacccc
tgcgctgaggaaaatgggggatgtagccatctctgcctctatagacctcagggccttcgc
tgtgcttgccctattggctttgaactcatcagtgacatgaagacctgcattgtcccagag
gctttccttttattttcacggagagcagatatcagacgaatttctttggaaacaaacaat
aataatgtggctattccactcactggtgtcaaagaagcttctgctttggattttgatgtg
acagacaaccgaatttattggactgatatatcactcaagaccatcagcagagcctttatg
aatggcagtgcactggaacatgtggtagaattcggcttagattatccagaaggcatggca
gtagactggcttgggaagaacttgtactgggcagacacaggaacgaatcgaattgaggtg
tcaaagttggatgggcagcaccgacaagttttggtgtggaaagacctagatagtcccaga
gctctcgcgttggaccctgccgaaggatttatgtattggactgaatggggtggaaagcct
aagatagacagagctgcaatggatggaagtgaacgtactaccttagttccaaatgtgggg
cgggcaaacggcctaactattgattatgctaaaaggaggctttattggacagacctggac
accaacttaatagaatcttcaaatatgcttgggctcaaccgtgaagttatagcagatgac
ttgcctcatccttttggcttaactcagtaccaagattatatctactggacggactggagc
cgacgcagcattgagcgtgccaacaaaaccagtggccaaaaccgcaccatcattcagggc
catttggattatgtgatggacatcctcgtctttcactcatctcgacagtcagggtggaat
gaatgtgcttccagcaatgggcactgctcccacctctgcttggctgtgccagttgggggt
tttgtttgtggatgccctgcccactactctcttaatgctgacaacaggacttgtagtgct
cctaccactttcctgctcttcagtcaaaagagtgccgtcaaccgcatggtgattgatgaa
caacagagccccgacatcatccttcccatccacagccttcggaatgtccgggccattgac
tatgacccactggacaagcaactctattggattgactcacgacaaaacatgatccgaaag
gcacaagaagatggcagccagggctttactgtggttgtgagctcagttccgagtcagaac
ctggaaatacaaccctatgacctcagcattgatatttatagccgctacatctactggact
tgtgaggctaccaatgtcattaatgtgacaagattagatgggagatcagttggagtggtg
ctaaaaggcgagcaggacagacctcgagccattgtggtaaacccagagaaagggtatatg
tattttaccaatcttcaggaaaggtctcctaaaattgaacgggctgctttggatgggaca
gaacgggaggtcctctttttcagtggcttaagtaaaccaattgctttagcccttgatagc
aggctgggcaagctcttttgggctgattcagatctccggcgaattgaaagcagtgatctc
tcaggtgctaaccggatagtattagaagactccaatatcttgcagcctgtgggacttact
gtgtttgaaaactggctctattggattgataaacagcagcaaatgattgaaaaaattgac
atgacaggtcgagagggtagaaccaaagtccaagctcgaattgctcagcttagtgacatt
catgcagtaaaggagctgaaccttcaagaatacagacagcacccttgtgctcaggataat
ggtggctgttcacatatttgtcttgtaaagggggatggtactacaaggtgttcttgtccc
atgcacctggttctgcttcaagatgagctatcatgtggagaacctccaacatgttctcct
cagcagtttacttgtttcacgggggagattgactgtatccctgtggcttggcggtgcgat
gggtttactgaatgtgaagaccacagtgatgaactcaattgtcctgtatgctcagagtcc
cagttccagtgtgccagtgggcagtgtattgatggtgccttccgatgcaatggagatgca
aactgccaggacaaatcagatgagaagaattgtgaagtgctttgtttaattgatcaattc
cgttgtgccaatggtcagtgcattggaaagcacaagaagtgtgatcataatgtggattgc
agtgacaagtcagatgaactggattgttatccaactgaagaaccagcaccacaggccacc
aatacagttggttctgttattggtgtaattgtcaccatttttgtgtctggaactatatac
tttatctgccagaggatgttgtgtccacgtatgaagggagatggggaaactatgactaat
gactatgtagttcatggaccagcttctgtgcctcttggttatgtgccacacccaggttct
ttgtcaggatctcttccaggaatgtctcgaggtaaatcaatgatcagctccctcagtatc
atggggggaagcagtggacccccctatgaccgagcccatgttacaggagcatcatcaagt
agttcttcaagcaccaaaggcacttacttccctgcaattttgaaccctccaccatcccca
gccacagagcgatcacattacactatggaatttggatattcttcaaacagtccttccact
cataggtcatacagctacaggccatatagctaccggcactttgcaccccccaccacaccc
tgcagcacagatgtttgtgacagtgactatgctcctagtcggagaatgacctcagtggca
acagccaagggctataccagtgacttgaactatgattcagaacctgtgcccccacctccc
acaccccgaagccaatacttgtcagcagaggagaactatgaaagctgcccaccttctcca
tacacagagaggagctattctcatcacctctacccaccgccaccctctccctgtacagac
tcctcctga |
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