Pongo abelii (Sumatran orangutan): 100454013
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Entry
100454013 CDS
T01416
Symbol
SRD5A2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00140
Steroid hormone biosynthesis
pon01100
Metabolic pathways
pon05215
Prostate cancer
Module
pon_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100454013 (SRD5A2)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
100454013 (SRD5A2)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
100454013 (SRD5A2)
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Motif
Pfam:
Steroid_dh
DUF1295
DUF6832
Motif
Other DBs
NCBI-GeneID:
100454013
NCBI-ProteinID:
XP_024098338
Ensembl:
ENSPPYG00000012512
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Position
12:101202068..101278255
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AA seq
254 aa
AA seq
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MQVQCQQSPVLAGSATLVALGALALYVAKPSGYGKHTESLMPAATRLPARAAWFLQELPS
FAVPAGILARQPLSLFGPPGTVLLGLFCVHYFHRTFVYSLLNRGRPYPAILILRGIAFCT
GNGVLQGYYLIYCAEYPDGWYTDIRFSLGVFLFILGMGINIHSDYILRQLRKPGEISYRI
PQGGLFTYVSGANFLGEIIEWIGYALATWSLPALAFAFFSLCFLGLRAFHHHRFYLKMFE
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcaggttcagtgccagcagagcccagtgctggcaggcagcgccactttggtcgccctt
ggggcactggccttgtacgtcgcgaagccctccggctacgggaagcacacggagagcctg
atgccggcggctacccgcctgccagcccgcgccgcctggttcctgcaggagctgccctcc
ttcgcggtgcccgcggggatcctcgcccggcagcccctctccctcttcgggccacctggg
acggtgcttctgggcctcttctgcgtacattacttccacaggacatttgtgtactcactg
ctcaatcgagggaggccttatccagctatactcattctcagaggcattgccttctgcact
ggaaatggagtccttcaaggctactatctgatttattgtgctgaataccctgatgggtgg
tacacagacatacggtttagcttgggtgtcttcttatttattttgggaatgggaatcaac
attcatagtgactatatattgcgccagctcaggaagcctggagaaatcagctacaggatt
ccacaaggtggcttgtttacgtatgtttctggagccaatttcctcggtgagatcattgaa
tggatcggctatgccctggccacttggtccctcccagcacttgcctttgcatttttctca
ctttgtttccttgggctgcgagcttttcaccaccataggttctacctcaagatgtttgag
gactaccccaaatctcggaaagcccttattccattcatcttttaa
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