Pongo abelii (Sumatran orangutan): 100454760
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Entry
100454760 CDS
T01416
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X2
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00061
Fatty acid biosynthesis
pon00620
Pyruvate metabolism
pon00640
Propanoate metabolism
pon01100
Metabolic pathways
pon01212
Fatty acid metabolism
pon04152
AMPK signaling pathway
pon04910
Insulin signaling pathway
pon04922
Glucagon signaling pathway
pon04936
Alcoholic liver disease
Module
pon_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
100454760 (ACACA)
00640 Propanoate metabolism
100454760 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
100454760 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
100454760 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
100454760 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
100454760 (ACACA)
04922 Glucagon signaling pathway
100454760 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100454760 (ACACA)
Enzymes [BR:
pon01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
100454760 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
100454760 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
100454760 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
100454760
NCBI-ProteinID:
XP_024090390
Ensembl:
ENSPPYG00000008216
LinkDB
All DBs
Position
19:51941410..52276750
Genome browser
AA seq
2385 aa
AA seq
DB search
MKMDKQASGAEWPLSSFWKWISTQTVKIIRALRAHFGGIMDEPSALAKPLELNQHSRFII
GSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHIRSSMSG
LHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWS
YEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIP
VQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWS
GSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGI
RKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQ
RRHQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPR
LQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAHVPCP
RGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCF
SWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKV
QAERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKY
VLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNK
TCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHY
VKRPGAALDPGCVLAKMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLV
NVMNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKE
MAQYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRG
HMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLV
TMLIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVE
SIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAY
ELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVL
LDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPPQSPTFPEAGHTSLYDEDKVP
RDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVN
YEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKM
HLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAF
NNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTP
TGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKD
LLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDD
QGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDLLFLR
ASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRV
SALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVT
CRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVT
HCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGR
PHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADP
ANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVL
KFGAYIVDGLRECSQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRGSVLEPE
GTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKEREEFLIPIYHQ
VAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTD
GQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEENIKCISRDYVL
KQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVVRILSTMDSPST
NT seq
7158 nt
NT seq
+upstream
nt +downstream
nt
atgaagatggataagcaggcatcaggagcagagtggcctctcagttctttttggaagtgg
atatctactcagacagtaaaaattataagagctctaagagctcattttggaggaataatg
gatgaaccatctgccttggccaaacctctggagctgaaccagcactctcgattcataata
ggttctgtgtctgaagataactcagaggatgagatcagcaacctggtgaagctggaccta
ctggaggagaaggagggctctttgtcacctgcttctgttggctcagatacactctctgat
ttggggatctctagcctacaggatggcttggccttgcacataaggtccagcatgtctggc
ttgcacctagtaaagcagggccgagacagaaagaaaatagattctcaacgagatttcact
gtggcttctccagcagaatttgttactcgctttgggggaaataaagtgattgagaaggtt
cttattgctaacaatggcattgcagcagtgaaatgcatgcggtctatccgtaggtggtct
tatgaaatgtttcgaaatgaacgtgcaattcgattcgttgtcatggtcacacctgaagac
cttaaagccaatgcagaatacattaagatggcagatcactatgtgccagtgcctggagga
ccaaacaacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatccca
gtacaagcagtgtgggctggctggggtcatgcttctgagaatcccaaactaccggaactt
ctcttgaaaaatggcatagccttcatgggtcctccaagccaggccatgtgggctttaggg
gataagattgcatcttccatagtggctcaaactgcaggtatcccaactcttccctggagc
ggcagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatcttaaatgtt
ccccaagagctatatgaaaaaggttatgtgaaagatgtggatgatgggctacaggcagct
gaggaagttggatatccagtaatgatcaaggcctcagagggaggaggagggaagggaatt
agaaaagtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtt
cctggatctcccatatttgtgatgagactagccaaacaatctcgtcatctggaggtgcag
atcttagcggaccaatatggcaatgctatctctttgtttggtcgtgattgctctgtacaa
cgcaggcatcagaagattattgaagaagcacctgctactattgctactccagcagtattt
gaacacatggaacagtgtgcggtgaaacttgccaaaatggtgggttatgtgagtgctggg
actgtggaatacctgtacagccaggatggcagcttctactttctggagttgaatcctcgg
ctgcaggtagagcacccttgtacagagatggtggctgatgtcaatctccctgcagcacag
ctccagattgccatggggattcctctatatagaatcaaggatatccgtatgatgtacgga
gtatctccctggggtgattctcccattgattttgaagattctgcacacgttccttgccca
aggggccatgttattgctgctcggatcactagtgaaaatccagatgagggttttaagccc
agctcaggaacagttcaggaactaaatttccgtagcaataagaatgtttggggatatttc
agtgttgccgctgcagggggacttcatgaatttgctgattctcagtttggtcactgcttt
tcttggggagaaaacagagaggaggcaatttcaaacatggtggtggctttgaaggagctg
tctattcggggtgactttcgaactacagttgaatacctgatcaaattgttagagactgaa
agctttcagatgaacagaattgatactggctggctggacagactgatagcagaaaaagta
caggctgaacgacctgacaccatgttgggggttgtgtgtggggccctccacgtggcagat
gtgagcctgcggaatagtgtctctaacttccttcactccttagaaaggggtcaagtcctt
cctgctcatacacttctgaatacagtagatgttgaacttatctatgagggagtcaagtat
gtacttaaggtgactcgacagtcccccaactcctatgtggtgatcatgaatggctcatgt
gtagaagtagatgtacatcggctgagtgacggtggactgctcttgtcctatgatggcagc
agttatactacgtatatgaaagaggaagtggataggtatcgcatcacgattggcaataaa
acctgtgtgtttgagaaggaaaatgacccatcggtgatgcgctcaccttctgctgggaag
ttaatccagtacattgtagaagatggaggtcatgtgtttgctggccagtgctatgctgag
attgaggtgatgaagatggtaatgaccttaacagctgtggagtctggctgtatccattac
gtcaagcgacctggagcagctcttgaccctggctgtgtactagccaaaatgcaactggac
aaccccagcaaggttcagcaggctgaacttcacacaggtagtctgccacggatccagagc
acggcactcagaggcgagaaactccatcgagtgttccattatgtcctggataatctggtc
aacgtaatgaatggatactgccttccagatcctttctttagcagcaaggtaaaagactgg
gtagagcgattgatgaaaaccctcagagatccctccctgcctctcctagaattgcaagat
atcatgaccagtgtgtctggccgcattccccccaatgtggagaagtctatcaagaaggaa
atggctcagtatgctagcaacatcacatcagtcctctgtcagtttcccagccagcagatt
gccaacatcctagatagccatgcagctacattgaaccggaaatctgaacgggaagtcttc
tttatgaatactcagagcattgttcagctggtacagaggtaccgaagtggcatccgaggc
cacatgaaggctgtggtgatggatctgctccggcagtacctgcgagtagagacacaattc
cagaatggtcactatgacaaatgtgtattcgccctccgggaagagaataaaagtgacatg
aacactgtactgaactacatcttctctcacgctcaagtcaccaagaagaatcttctggtc
acaatgcttattgatcagttgtgtggccgggaccctactctcactgatgagctgctgaat
attctcacagagctaactcaactcagtaagaccaccaatgccaaagtagcacttcgagca
cgccaggttcttattgcctcccatttgccatcatatgagcttcgccataaccaagtagag
tctatcttcctatcagctattgacatgtatggacatcaattttgcattgagaacctgcag
aaactcatcctatcagaaacatctatttttgatgtcctaccaaacttcttctatcacagc
aaccaagtagtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcctac
gaacttaacagtgtacaacaccgccagcttaaggacaacacctgtgtggtggaattccag
ttcatgctgcccacatctcatccaaacagagggaacatccctacgctaaacagaatgtcc
ttctcctccaacctcaaccactatggcatgacccatgtagctagtgtcagcgatgtactg
ttggacaactcattcactccaccttgtcagcggatgggcggaatggtctcttttcggact
tttgaagattttgtcaggatctttgatgaagtgatgggctgcttctctgactccccaccc
cagagtcccacattcccggaggcgggtcacacgtctctttatgatgaagataaggttccc
agggatgaaccaattcacattctcaatgtggctatcaagactgactgtgatattgaggat
gacaggctggcagctatgttcagagaatttacccagcaaaataaagctaccctggttgac
catgggatccggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtcaac
tatgaggtggatcagagatttcatagagaattccctaaattttttacattccgagcaagg
gataagtttgaggaggatcgtatctatcgtcatctggagcctgctctggctttccagtta
gagctgaaccggatgagaaattttgacctcactgccattccatgtgctaatcacaagatg
cacctgtatctcggggcagccaaggtggaagtgggcacggaagtgacagactacaggttc
tttgttcgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcttttgaatat
ctgcaaaatgaaggggagcggctactcctggaagccatggatgagttggaagttgctttt
aacaatacaaatgtccgcactgactgtaaccacatcttcctcaactttgtgcccacggtt
atcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcggtatggaagt
cgcctttggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgacgcca
actggaaaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttggat
atcagcctatacaaggaagtgactgactccaggacagcacagatcatgtttcaggcatat
ggagacaaacagggaccactgcatggaatgttaatcaatactccttatgtgaccaaagac
ctgctgcaatcaaagaggttccaggcacaatccttagggacaacatacatatatgatatc
ccagagatgtttcggcagtccctgatcaaactctgggagtctatgtccactcaagcattt
cttccatctccccctctgccttctgacatgctgacttacactgaactggtattggatgat
caaggtcagctggtccacatgaacaggcttccaggaggaaatgagattggcatggtagct
tggaaaatgacctttaaaagtcctgaatatccagaaggccgagatatcattgttattggc
aatgacatcacataccgaattgggtcctttgggcctcaagaggatttgttatttctcaga
gcttctgaacttgctagggcagaaggtattccacgcatctatgtatcagccaacagtgga
gcaagaatcggactggcagaagaaattcgtcatatgtttcatgtggcctgggtagatcct
gaggatccttacaagggatacaggtatttgtatctgacccctcaagattataagagagtc
agtgctctcaactctgtccattgtgaacacgtggaggatgaaggagaatccaggtacaag
ataacagatattattgggaaagaagagggaattggacctgagaaccttcgaggttctgga
atgattgctggagaatcctcattggcctataatgagatcattaccatcagcctggtgacg
tgccgggccattgggattggggcttaccttgtccggctgggacagagaaccatccaggtt
gagaattctcacttaattctaacaggagctggagccctcaacaaagtcctcgggcgggaa
gtgtacacctccaataaccagctggggggcatccagattatgcacaacaatggggtgacc
cactgcactgtgtgtgatgactttgaaggggttttcactgtcctgcactggctgtcttac
atgcccaagagcgtgcacagttcagttcctcttctgaactcaaaggatcctatagacaga
atcatcgagtttgttcccacaaaggccccatatgatcctcgatggatgctagcaggccgt
cctcacccaacccaaaaaggtcagtggttgagtggcttttttgactacggatctttctca
gagattatgcagccctgggcacagactgtggtggttggtagagccaggctaggaggaata
cctgtgggagttgttgctgtagaaacccgaacagtagaactaagtatcccagctgatcca
gcaaacctggattctgaagccaagataatccagcaggctggccaggtttggttcccagat
tctgcgtttaagacgtatcaggccatcaaggacttcaaccgggaagggctgcctctgatg
gtctttgccaactggagaggcttctctggtggaatgaaagatatgtacgaccaagtgctg
aagtttggtgcttacattgtggacggcttgagggagtgctcccagcctgtgctggtttac
attcctccccaggctgagctgcggggtggctcctgggtggtgattgactcctccatcaac
ccccggcacatggagatgtatgctgaccgagaaagcaggggatctgttctggagccagaa
gggacagtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggac
ccagtctacatccacttggctgagcgattggggaccccagagctaagcacagctgagcgg
aaggagttggagaacaagttgaaggagcgggaggaattcctaattcccatttaccatcag
gtagccgtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggtgtt
attagcgatatcctggattggaaaacatcccgtaccttcttctactggcggctgaggcgt
cttctgctggaggacctggtcaagaagaaaatccacaatgccaaccctgagctgactgac
ggccagattcaagccatgttaaggcgctggtttgtggaagtggaaggaacagtaaaggcc
tatgtttgggacaataataaggatctggcagagtggctagagaaacagctgacagaggag
gatggtgttcactcggtaatagaggaaaacatcaaatgcatcagcagagactacgtcctc
aagcaaatccgcagcttggtccaggccaatccagaggttgccatggattccatcatccat
atgacccagcacatatcacccactcagcgagcagaagtcgtacggatcctctccacaatg
gattccccttccacgtag
DBGET
integrated database retrieval system
