KEGG   Pongo abelii (Sumatran orangutan): 100454860
Entry
100454860         CDS       T01416                                 
Symbol
PIEZO1
Name
(RefSeq) piezo-type mechanosensitive ion channel component 1 isoform X1
  KO
K22128  piezo-type mechanosensitive ion channel component 1/2
Organism
pon  Pongo abelii (Sumatran orangutan)
Brite
KEGG Orthology (KO) [BR:pon00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pon04131]
    100454860 (PIEZO1)
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pon04040]
    100454860 (PIEZO1)
Membrane trafficking [BR:pon04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Others
   Others
    100454860 (PIEZO1)
Ion channels [BR:pon04040]
 Other channels
  Mechanosensitive channel (Piezo)
   100454860 (PIEZO1)
SSDB
Motif
Pfam: Piezo_TM1-24 Piezo_TM25-28 Piezo_cap Piezo_THU9_anchor THU_Piezo1
Other DBs
NCBI-GeneID: 100454860
NCBI-ProteinID: XP_024089738
LinkDB
Position
18:complement(88163627..88232755)
AA seq 2520 aa
MEPHVLGAVLYWLLLPCALLAACLLRFSGLSLVYLLFLLLLPWFPGPTRRSLQGHTGRLL
RALLGLSLLFLVAHLTLQICLHTVPHLDQLLGPSCSRWETLSRHIGVTRLDLKDIPNTIR
LVAPDLGILVVSSVCLGLCRRLARNTRQSPHPRELDDDERDVDASPPAGLQEAATLAPTR
RSRLAARFRVTAHWLLVAAGRVLVVTLLALAGIAHPSALSSVYLLVFLAICTWWACHFPI
STRGFSRLCVAVGCFGAGHLICLYCYQTPLAQALLPPAGIWARVLGLKDFVGPTNCSSPH
ALVLNTSLDWPVYASPGVLLLLCYATASLRKLRAYRPSGQRKEAAKGDEARELELAELDQ
WPQDREADQHVVPTAPDTEADNCIVHELTGQSSLRQRPVRPKQAEPREASPLHSLGHLIM
DQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWMVRSRHQLAMLCSPCILLYGMTLCCL
RYVWAMDLHPELPTTLGPVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLK
WAESPAALMEVTVADTAWPTEPTRTQTLLQSLGELVKGVYAKFWIYVCAGMFIVVSFAGR
LVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYW
RNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSP
PGTRLPRWAHRQDTVSGTPLLQEEQQQQQQEEEEEDSRDEGLGVATPHQAMQVPEGAAKW
GLVAERLLELAAGFSDVLSRVQVFLRRLLELHIFKLVALYTVWVALKEVSVMNLLLVVLW
AFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPSPNSTNLLPTEI
SQSLLYRGPVDPANWFGVRKGFPNLGYIQNHLQVLLLLVFEAIVYRRQEHYRRQHQLAPL
PAQVVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFMVTLHGCW
LVAILTRRRRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSAL
IKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRGE
PNPVPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGT
ALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFSLVCTVK
GYYDPKEMMDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLA
SRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRADRSRPQETLGPK
DPGPEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEAAPEDPRPSAQ
SAFQLAYQAWVTNAQTVLRRRQQEQEQARQEQAGQLPTGGGPSQEVEPAEGSEEAAAGRS
HMVQRVLSTAQFLWMLGQALVDGLTRWLQEFTRHHSTMSDVLRAERYFLTQELLQGGEVH
RGVLDQLYTSQAEATLPGPTEAPNAPSTVSSGLGAEEPLSGMTDDTGSPLSTGYHTRSGS
EEAVTDPGEREAGASLYQGRMRTASELLLDRRLHIPELEEAELFAEGQGRALQLLRAVYQ
CVAAHSELLCYFIIILNHVVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEVTV
VVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLL
CYGLWDHEEDSPSKEHDKSGEEEQGAEEGPGVPGVTTKDHVQVKARVGPTDGTPEPQVEL
RPRDTRRISLRFRRRKKEGPARKGPAAIEAEDREEEEGEEEKEAPTGREKRPSRSGGRVR
AAGRRLQGFCLSLAQGTYRPLRHFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWA
FGKHSAATDITSSLSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVVLVLAI
HLWMFFILPAVTERMFSQNAVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHL
NLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQ
PKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEP
LFTMSAQQPSITPFTAQAYEALSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRIS
PPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASL
LEGTSDQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGFL
EWWVIELQECRTDCNLLPMVIFSDKVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFSE
ISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE
NT seq 7563 nt   +upstreamnt  +downstreamnt
atggagccgcacgtgctcggcgcggtcctgtactggctgctgctgccctgcgcgctgctg
gctgcctgcctgctccgcttcagtggactctcgctagtctacctgctcttcctgctgctg
ctgccctggttccccggccctacccgacgtagcctccaaggtcacacaggccgcctcctg
cgggcattgctgggcctcagcctgctcttcctggtcgcccatctcaccctccagatctgc
ctgcacactgtgccccacctggaccagctcctgggacccagctgcagccgctgggagacc
ctctcgcgacacataggggtcacaaggctggacctgaaggacatccccaacaccatccgg
ctggtggcccctgacctgggcatcctggtggtctcctctgtctgcctcggcctctgcagg
cgcctcgcgaggaacacccggcagagcccacatccacgggagctggatgacgacgagagg
gatgtggatgccagccccccggcagggctgcaggaagcagcaacgctggcccctacacgg
aggtcacggctggccgctcgtttccgagtcacagcccattggctgctggtggcagctggg
cgggtcctggtcgtaacactgcttgcactggcaggcatcgcccacccctcggccctctcc
agtgtctacctgctggtgttcctggccatctgcacctggtgggcctgccactttcccatc
agcactcggggcttcagcagactctgcgtcgcggtggggtgcttcggcgccggccatctc
atctgcctctactgctaccagacgcccttggcacaggctctgctcccgcctgccggcatc
tgggctagggtgctgggtctcaaggacttcgtgggtcccaccaactgctccagcccccac
gcgctggtcctcaacaccagcctggactggcctgtgtatgccagccccggtgtcctgctg
ctgctgtgctacgccacggcctctctgcgcaagctccgtgcgtaccgcccctccggccag
aggaaggaggcggcaaagggggacgaggctcgggagctggagctagcagagctggaccag
tggccccaggatcgggaggctgaccagcacgtggtgcccacagcacccgacaccgaggct
gataactgcatcgtgcacgagctgactggccagagctccctccggcagcggcctgtgcgg
cccaagcaggctgagcccagggaggcgtccccgctccacagcctgggccacctcatcatg
gaccagagctatgtgtgcgcgctcatcgccatgatggtgtggagcatcacctaccacagc
tggctgaccttcgtgctgctgctctgggcctgcctcatctggatggtgcgcagccgccac
caactggccatgctgtgctcgccctgcatcctgctgtacgggatgacgctgtgctgtcta
cgctacgtgtgggccatggacctgcaccctgagctgcccaccaccctgggccccgtcagc
ctgcgccagctggggctggagcacacccgctacccctgcctggaccttggtgccatgttg
ctctacaccctgacgttctggctcctgctgcgccagtttgtgaaagagaagctgctgaag
tgggcagagtctccagctgcgctgatggaggtcaccgtggcagacacagcttggcccaca
gagcccacgcggacacagacgctgttgcagagcctgggggagctggtgaagggcgtgtat
gccaagttctggatctatgtgtgtgctggcatgttcattgtggtcagctttgccggccgc
ctcgtggtctacaagattgtctacatgttcctcttcctgctctgcctcaccctcttccag
gtgtactacagcctgtggcggaagctcctcaaggccttctggtggctcgtggtggcctac
accatgctggtcctcatcgccgtctacaccttccagttccaggacttccctgcatactgg
cgcaacctcaccggcttcaccgacgagcagctgggggacctgggcctggagcagttcagc
gtgtccgagctcttctccagcatcctggtgcccggcttcttcctgctggcctgcatcctg
cagctgcactactttcaccggccctttatgcagctcaccgacatggagcacgtgtccccg
cctggcacgcgcctcccgcgctgggctcacaggcaggatacagtgagcgggaccccactg
ctgcaggaggagcagcagcagcagcagcaggaggaggaggaggaggactccagggacgag
gggctgggtgtggccactccccaccaggccatgcaggtacctgaaggtgcagccaagtgg
ggcctggtggccgagcggctgctggagctggcagccggcttctcggacgtcctctcacgc
gtgcaggtgttcctgcggcggctgctggagcttcacatcttcaagctggtggccctgtac
accgtctgggtggccctgaaggaggtgtcggtgatgaacctgctgctggtggtgctgtgg
gccttcgccctgccctacccacgcttccgacccatggcctcctgcctgtccactgtgtgg
acctgcgtcatcatcgtgtgtaagatgctgtaccagctcaaggttgtcaacccccaggag
tattccagcaactgcaccgagccctcccccaacagcaccaacttgctgcccacggagatc
agccagtccctgctgtaccgggggcccgtggaccctgccaactggtttggggtgcggaaa
gggttccccaacctgggctacatccagaaccacctgcaggtcctgctgctgctggtattc
gaggccatcgtgtaccggcgccaggagcactaccgccggcagcaccagctggccccgctg
cctgcccaggttgtgtttgccagcggcacccgccagcagctggaccaggatctgctcggc
tgcctcaagtacttcatcaacttcttcttctacaaattcgggctggagatctgcttcctg
atggccgtgaacgtgatcgggcagcgcatgaactttatggtgaccctgcacggctgctgg
ctggtggccatcctcacccgcaggcgccgccaggccatcgcccgcctctggcccaactac
tgcctgttcctggcgctgttcctgctgtaccagtacctgctgtgcctggggatgcccccg
gccctgtgcatcgattacccgtggcgctggagccgggccgtccccatgaactccgcactc
atcaagtggctgtacctgcctgatttcttccgggcccccaactccaccaacctcatcagt
gatttcctcctgctgctctgcgcctcccagcagtggcaggtgttctcggctgagcgcacg
gaggagtggcagcgcatggctggcgtcaacaccgaccgcctggagccactgcggggggag
cccaaccctgtgcccaactttatccactgcaggtcctatcttgacatgctgaaggtggcc
gtcttccgatacctgttctggttggtgctggtggtggtgtttgtcacgggggccacccgc
atcagcatcttcgggctgggctacctgctggcctgcttctacctgctgctcttcggcacc
gccctgctgcagagggacacgcgggcccgcctcgtgctgtgggactgcctcattctgtac
aacgtcaccgtcatcatctccaagaacatgctgtcgctcctggcctgcgtcttcgtggag
cagatgcagactggcttctgctgggtcatccagctcttcagccttgtgtgcaccgtcaag
ggctactatgaccccaaggagatgatggacagagaccaggactgcctgctgcctgtggag
gaggctggcatcatctgggacagcgtctgcttcttcttcttgctgctgcagcgccgcgtc
ttccttagccattactacctgcacgtcagggccgacctccaggccactgccctgctagcc
tccaggggcttcgccctctacaatgctgccaacctcaagagcatcgacttccaccgcagg
atagaggagaagtccctggcccagctgaaaagacagatggagcgtatccgtgccaagcag
gagaagcacaggcagggccgggcggaccgcagtcgcccccaggaaaccctgggccccaag
gaccccggcccggagccagggcccgacagtccagggggctcctccccgccacggaggcag
tggtggcggccctggctggaccatgccacagtcatccactccggggactacttcctgttt
gagtccgacagcgaggaagaggaggaggctgcccctgaagaccctaggccgtcggcacag
agtgccttccagctggcgtaccaggcatgggtgaccaacgctcagacggtgctgaggcgg
cggcagcaggaacaggagcaggcaaggcaggagcaggcaggacagctacccacaggaggt
ggccccagccaggaggtggaaccggcagagggctccgaggaggcagcggcaggccggagc
cacatggtgcagagggtgctgagcacggcgcagttcctgtggatgctggggcaggcgcta
gtggacgggctgacacgctggctgcaggagttcacccggcaccatagcaccatgagcgac
gtgctgcgggcagagcgctacttcctcacacaggagctcctgcagggcggtgaagtgcac
cggggcgtgttggatcagctgtacacaagccaggccgaggccacactgccaggccccacc
gaggcccccaatgccccaagcaccgtgtccagtgggctgggcgcggaggagccgctcagc
ggcatgacagacgacacgggcagccccctgagcaccggctaccacacgcgcagtggcagt
gaggaggcggtcaccgaccccggggagcgcgaggctggcgcctctctgtaccagggacgg
atgcggacggccagcgagctgctcctggacaggcgcctgcacatcccagagctagaggag
gcagagctgtttgcggaggggcagggccgggcgctgcagctgctgcgggccgtgtaccag
tgcgtggccgcccactcggagctgctctgctacttcatcatcatcctcaaccacgtggtc
acggcctccgccggctcgctggtgctgcccgtgcttgtcttcctgtgggccatgctgtcc
atcccgaggcccagcaagcgcttctggatgacggccatcgtcttcaccgaggttacagtg
gtcgtcaagtacctgttccagtttgggttcttcccctggaacagccacgtggtgctgcgg
cgctacgagaacaagccctacttcccgccccgcatcctgggcctggagaagactgacggc
tacatcaagtacgacctggtgcagctcatggccctcttcttccaccgctcccagctgctg
tgctatggcctctgggaccacgaggaggactcaccatccaaggagcatgacaagagcggc
gaggaggagcagggagccgaggaggggccaggggtgcctggggtcaccaccaaggaccac
gttcaggtgaaagcgagggtcggacctacggacgggaccccagaaccccaggtggagctc
aggccccgtgacacgaggcgcatcagtctacgttttagaagaaggaagaaggagggccca
gcacggaaaggaccggcagccatcgaagctgaggacagggaggaagaagagggggaggaa
gagaaagaggcccccacggggagagagaagaggccaagccgctctggaggaagagtaagg
gcggccgggcggcggctgcagggcttctgcctgtccctggcccagggcacataccggccg
ctacggcacttcttccacgacatcctgcacaccaagtaccgcgcagccaccgacgtctat
gccctcatgttcctggctgatgttgtcgacttcatcatcatcatttttggcttctgggcc
tttgggaagcactcggcggccacggacatcacgtcctccctatcagacgaccaggtaccc
gaggccttcctggtcatgctgctgatccagttcagcaccatggtggtggaccgcgccctc
tacctgcgcaagaccgtgttgggcaagctggccttccaggtggtgctggtgctggccatc
cacctatggatgttcttcatcctgcccgccgttactgagaggatgttcagccagaatgcg
gtggcccagctgtggtacttcgtgaaatgcatctacttcgccctgtccgcctaccagatc
cgctgcggctaccccacccgcatcctcggcaacttcctcaccaagaagtacaatcacctc
aacctcttcctcttccaggggttccggctggtgccgttcctggtggagctgcgggcagtg
atggactgggtgtggacggacaccacgctgtccctgtccagctggatgtgcgtggaggac
atctatgccaacatcttcatcatcaaatgcagccgagagacagagaagaaatacccgcag
cccaaagggcagaagaagaagaagatcgtcaagtacggcatgggtggcctcatcatcctc
ttcctcatcgccatcatctggttcccgctgctcttcatgtcgctggtgcgctccgtggtc
ggggttgtcaaccagcccatcgatgtcactgtcaccctcaagctcggtggctatgagccg
ctgttcaccatgagcgcccagcagccgtccatcacccccttcacggcccaggcctatgag
gcgctgtcccggcagtttgacccccagccgctggccatgcagttcatcagccagtacagc
cctgaggacatcgtcacggcacagatagagggcagctccggggcgctgtggcgcattagc
ccaccaagccgtgcccagatgaagcgggaactctacaacggcacggccgacatcaccctg
cgcttcacctggaacttccagagggacctggccaagggaggcaccgtggagtatgccaac
gagaagcacatgctggccctggcccccaatagcactgcacggcggcagctggccagcctg
ctcgagggcacctcggaccagtctgtggtcatccccaatctcttccccaagtacatccgt
gcccccaacgggcccgaagccaaccctgtgaagcagctgcagcccaatgaggaggccgac
tacctcggcgtgcgtatccagctgcggagggagcagggtgcgggggccaccggcttcctc
gaatggtgggtcatcgagctgcaggagtgccggaccgactgcaacctgctgcccatggtc
attttcagcgacaaggtcagcccaccgagcctcggcttcctggctggctacggcatcatg
gggctgtacgtgtccatcgtgctggtcatcggcaagttcgtgcgcggattcttcagcgag
atctcgcactccattatgttcgaggagctgccgtgcgtggaccgcatcctcaagctctgc
caggacatcttcctggtgcgggagactcgggagctggagctggaggaggagttgtacgcc
aagctcatcttcctctaccgctccccggagaccatgatcaagtggactcgtgagaaggag
tag

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