KEGG   Pongo abelii (Sumatran orangutan): 100455542
Entry
100455542         CDS       T01416                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04010  MAPK signaling pathway
pon04020  Calcium signaling pathway
pon04022  cGMP-PKG signaling pathway
pon04114  Oocyte meiosis
pon04218  Cellular senescence
pon04310  Wnt signaling pathway
pon04360  Axon guidance
pon04370  VEGF signaling pathway
pon04380  Osteoclast differentiation
pon04625  C-type lectin receptor signaling pathway
pon04650  Natural killer cell mediated cytotoxicity
pon04658  Th1 and Th2 cell differentiation
pon04659  Th17 cell differentiation
pon04660  T cell receptor signaling pathway
pon04662  B cell receptor signaling pathway
pon04720  Long-term potentiation
pon04724  Glutamatergic synapse
pon04728  Dopaminergic synapse
pon04921  Oxytocin signaling pathway
pon04922  Glucagon signaling pathway
pon04924  Renin secretion
pon05010  Alzheimer disease
pon05014  Amyotrophic lateral sclerosis
pon05020  Prion disease
pon05022  Pathways of neurodegeneration - multiple diseases
pon05031  Amphetamine addiction
pon05152  Tuberculosis
pon05163  Human cytomegalovirus infection
pon05166  Human T-cell leukemia virus 1 infection
pon05167  Kaposi sarcoma-associated herpesvirus infection
pon05170  Human immunodeficiency virus 1 infection
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pon05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100455542 (PPP3CC)
   04310 Wnt signaling pathway
    100455542 (PPP3CC)
   04370 VEGF signaling pathway
    100455542 (PPP3CC)
   04020 Calcium signaling pathway
    100455542 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    100455542 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100455542 (PPP3CC)
   04218 Cellular senescence
    100455542 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    100455542 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    100455542 (PPP3CC)
   04660 T cell receptor signaling pathway
    100455542 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    100455542 (PPP3CC)
   04659 Th17 cell differentiation
    100455542 (PPP3CC)
   04662 B cell receptor signaling pathway
    100455542 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100455542 (PPP3CC)
   04921 Oxytocin signaling pathway
    100455542 (PPP3CC)
   04924 Renin secretion
    100455542 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    100455542 (PPP3CC)
   04728 Dopaminergic synapse
    100455542 (PPP3CC)
   04720 Long-term potentiation
    100455542 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    100455542 (PPP3CC)
   04380 Osteoclast differentiation
    100455542 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100455542 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    100455542 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    100455542 (PPP3CC)
   05163 Human cytomegalovirus infection
    100455542 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100455542 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100455542 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100455542 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    100455542 (PPP3CC)
   05020 Prion disease
    100455542 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    100455542 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    100455542 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100455542 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pon01009]
    100455542 (PPP3CC)
Enzymes [BR:pon01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100455542 (PPP3CC)
Protein phosphatases and associated proteins [BR:pon01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     100455542 (PPP3CC)
SSDB
Motif
Pfam: Metallophos DUF5378 DUF7084
Other DBs
NCBI-GeneID: 100455542
NCBI-ProteinID: XP_002818927
Ensembl: ENSPPYG00000018422
UniProt: H2PPS1
LinkDB
Position
7:24252613..24351647
AA seq 511 aa
MSGRRFHLSTTDRVIKAVPFPPTQRLTFKEVFENGKPKVDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNVLNICSDDELISDDEAEGSTTVRKEIIRNKIRAIGKMARVFSILRQESESVLTLKGL
TPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHKIRSFEEARGLDRINERMPPR
KDSIHADGPMKSVTSAHSHAAHRSDQGKKAQ
NT seq 1536 nt   +upstreamnt  +downstreamnt
atgtccgggaggcgcttccacctctccaccaccgaccgcgtcatcaaagctgtccccttt
cctccaacccaacggcttactttcaaggaagtatttgagaatgggaaacctaaagttgat
gttttaaaaaaccatttggtaaaggaaggacgactggaagaggaagtagccttaaagata
atcaatgatggggctgccatcctgaggcaagagaagactatgatagaagtagatgctcca
atcacagtatgtggtgatattcatggacaattctttgacctaatgaagttatttgaagtt
ggaggatcacctagtaatacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtatttatggagtttaaagattaatcatcccaaaacattg
tttctgcttcggggaaatcatgaatgcaggcatcttacagactatttcaccttcaaacag
gaatgtcgaatcaaatattcggaacaggtgtatgatgcctgtatggagacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctctgtgtacatggaggaatgtcacct
gaaattacttctttagatgacattaggaaattagacaggtttacggaacctcccgcgttt
ggacctgtgtgtgacctgctttggtctgatccctcagaggattatggcaatgagaagacc
ttggagcactatacccacaacactgtccgagggtgctcttatttctacagttaccctgca
gtttgtgaatttttgcagaacaataatttactatcaattatcagagcccatgaagcccaa
gatgctgggtatcgaatgtacaggaagagccaagcaacaggctttccatcacttattaca
attttctctgcccccaattacctagatgtctataacaataaagctgctgtgttgaaatat
gaaaacaatgtcatgaatatcaggcagtttaactgttctccacacccctactggcttcca
aactttatggatgttttcacatggtctttgccttttgttggggaaaaagtcacagagatg
ctggtaaatgtgctcaacatatgctctgatgacgaactgatttctgatgatgaagcagaa
ggaagcactacagttcgtaaggagatcatcaggaataagatcagagccattgggaagatg
gcacgggtcttttcaattcttcggcaagaaagtgagagtgtactgactctcaagggcctg
actcccacaggcacgctccctctgggcgtcctctctggaggcaagcagactatcgagaca
gccacagtagaagcggtagaggcccgggaagccatcagagggttctcgcttcagcacaag
attcggagttttgaagaagcgcgaggtctggaccgaattaatgagcgaatgccaccccga
aaggatagcatacacgctgatgggccaatgaaatctgtaacctcagcacactcacatgct
gcacacaggagcgaccaagggaagaaagcccagtaa

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