KEGG   Pongo abelii (Sumatran orangutan): 100456988
Entry
100456988         CDS       T01416                                 
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon01521  EGFR tyrosine kinase inhibitor resistance
pon01522  Endocrine resistance
pon04012  ErbB signaling pathway
pon04066  HIF-1 signaling pathway
pon04140  Autophagy - animal
pon04150  mTOR signaling pathway
pon04151  PI3K-Akt signaling pathway
pon04152  AMPK signaling pathway
pon04211  Longevity regulating pathway
pon04213  Longevity regulating pathway - multiple species
pon04350  TGF-beta signaling pathway
pon04371  Apelin signaling pathway
pon04666  Fc gamma R-mediated phagocytosis
pon04714  Thermogenesis
pon04910  Insulin signaling pathway
pon04931  Insulin resistance
pon05163  Human cytomegalovirus infection
pon05165  Human papillomavirus infection
pon05170  Human immunodeficiency virus 1 infection
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05207  Chemical carcinogenesis - receptor activation
pon05210  Colorectal cancer
pon05212  Pancreatic cancer
pon05221  Acute myeloid leukemia
pon05224  Breast cancer
pon05225  Hepatocellular carcinoma
pon05226  Gastric cancer
pon05231  Choline metabolism in cancer
pon05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    100456988 (RPS6KB1)
   04350 TGF-beta signaling pathway
    100456988 (RPS6KB1)
   04371 Apelin signaling pathway
    100456988 (RPS6KB1)
   04066 HIF-1 signaling pathway
    100456988 (RPS6KB1)
   04151 PI3K-Akt signaling pathway
    100456988 (RPS6KB1)
   04152 AMPK signaling pathway
    100456988 (RPS6KB1)
   04150 mTOR signaling pathway
    100456988 (RPS6KB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100456988 (RPS6KB1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    100456988 (RPS6KB1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    100456988 (RPS6KB1)
  09149 Aging
   04211 Longevity regulating pathway
    100456988 (RPS6KB1)
   04213 Longevity regulating pathway - multiple species
    100456988 (RPS6KB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    100456988 (RPS6KB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100456988 (RPS6KB1)
   05205 Proteoglycans in cancer
    100456988 (RPS6KB1)
   05207 Chemical carcinogenesis - receptor activation
    100456988 (RPS6KB1)
   05231 Choline metabolism in cancer
    100456988 (RPS6KB1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100456988 (RPS6KB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100456988 (RPS6KB1)
   05212 Pancreatic cancer
    100456988 (RPS6KB1)
   05225 Hepatocellular carcinoma
    100456988 (RPS6KB1)
   05226 Gastric cancer
    100456988 (RPS6KB1)
   05221 Acute myeloid leukemia
    100456988 (RPS6KB1)
   05224 Breast cancer
    100456988 (RPS6KB1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100456988 (RPS6KB1)
   05163 Human cytomegalovirus infection
    100456988 (RPS6KB1)
   05165 Human papillomavirus infection
    100456988 (RPS6KB1)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100456988 (RPS6KB1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100456988 (RPS6KB1)
   01522 Endocrine resistance
    100456988 (RPS6KB1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pon01001]
    100456988 (RPS6KB1)
Enzymes [BR:pon01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100456988 (RPS6KB1)
Protein kinases [BR:pon01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   100456988 (RPS6KB1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 DUF1015
Other DBs
NCBI-GeneID: 100456988
NCBI-ProteinID: XP_054392986
Ensembl: ENSPPYG00000008807
LinkDB
Position
19:complement(55855707..55978748)
AA seq 525 aa
MRRRRRRDGFYPAPDFRDKEAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgaggcgacggaggaggcgggacggcttttacccagcgccggacttccgagacaaggaa
gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagaacggaatattctggaggaagtaaagcatcccttcatcgtggatttaatttat
gcctttcagactggtggaaaactctacctcatccttgagtatctcagtggaggagaacta
tttatgcagttagaaagagagggaatatttatggaagacactgcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaagaatctattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccattcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtctgggagctggtcct
ggggacgctggagaagttcaagctcatccattcttcagacacattaactgggaagaactt
ctggctcgaaaggtggagcccccctttaaacctctgttgcaatctgaagaggatgtaagt
cagtttgattccaagtttacacgtcagacacctgtcgacagcccagatgactcaactctc
agtgaaagtgccaatcaggtctttctgggttttacatatgtggctccatctgtacttgaa
agtgtgaaagaaaagttttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcggccagcacagcaaatcctcagacacctgtggaatacccaatggaaacaagtggc
atagagcagatggatgtcacaatgagtggggaagcatcggcaccacttccaatacgacag
ccgaactctgggccatacaaaaaacaagcttttcccatgatctccaaacggccagagcac
ctgcgtatgaatctatga

DBGET integrated database retrieval system