Pongo abelii (Sumatran orangutan): 100458733
Help
Entry
100458733 CDS
T01416
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
KO
K03099
son of sevenless
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon01522
Endocrine resistance
pon04010
MAPK signaling pathway
pon04012
ErbB signaling pathway
pon04014
Ras signaling pathway
pon04062
Chemokine signaling pathway
pon04068
FoxO signaling pathway
pon04072
Phospholipase D signaling pathway
pon04150
mTOR signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04510
Focal adhesion
pon04540
Gap junction
pon04630
JAK-STAT signaling pathway
pon04650
Natural killer cell mediated cytotoxicity
pon04660
T cell receptor signaling pathway
pon04662
B cell receptor signaling pathway
pon04664
Fc epsilon RI signaling pathway
pon04714
Thermogenesis
pon04722
Neurotrophin signaling pathway
pon04810
Regulation of actin cytoskeleton
pon04910
Insulin signaling pathway
pon04912
GnRH signaling pathway
pon04915
Estrogen signaling pathway
pon04917
Prolactin signaling pathway
pon04926
Relaxin signaling pathway
pon04935
Growth hormone synthesis, secretion and action
pon05034
Alcoholism
pon05160
Hepatitis C
pon05161
Hepatitis B
pon05163
Human cytomegalovirus infection
pon05165
Human papillomavirus infection
pon05200
Pathways in cancer
pon05205
Proteoglycans in cancer
pon05206
MicroRNAs in cancer
pon05207
Chemical carcinogenesis - receptor activation
pon05208
Chemical carcinogenesis - reactive oxygen species
pon05210
Colorectal cancer
pon05211
Renal cell carcinoma
pon05213
Endometrial cancer
pon05214
Glioma
pon05215
Prostate cancer
pon05220
Chronic myeloid leukemia
pon05221
Acute myeloid leukemia
pon05223
Non-small cell lung cancer
pon05224
Breast cancer
pon05225
Hepatocellular carcinoma
pon05226
Gastric cancer
pon05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100458733 (SOS1)
04012 ErbB signaling pathway
100458733 (SOS1)
04014 Ras signaling pathway
100458733 (SOS1)
04630 JAK-STAT signaling pathway
100458733 (SOS1)
04068 FoxO signaling pathway
100458733 (SOS1)
04072 Phospholipase D signaling pathway
100458733 (SOS1)
04151 PI3K-Akt signaling pathway
100458733 (SOS1)
04150 mTOR signaling pathway
100458733 (SOS1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100458733 (SOS1)
04540 Gap junction
100458733 (SOS1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100458733 (SOS1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100458733 (SOS1)
04660 T cell receptor signaling pathway
100458733 (SOS1)
04662 B cell receptor signaling pathway
100458733 (SOS1)
04664 Fc epsilon RI signaling pathway
100458733 (SOS1)
04062 Chemokine signaling pathway
100458733 (SOS1)
09152 Endocrine system
04910 Insulin signaling pathway
100458733 (SOS1)
04912 GnRH signaling pathway
100458733 (SOS1)
04915 Estrogen signaling pathway
100458733 (SOS1)
04917 Prolactin signaling pathway
100458733 (SOS1)
04926 Relaxin signaling pathway
100458733 (SOS1)
04935 Growth hormone synthesis, secretion and action
100458733 (SOS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
100458733 (SOS1)
09159 Environmental adaptation
04714 Thermogenesis
100458733 (SOS1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100458733 (SOS1)
05206 MicroRNAs in cancer
100458733 (SOS1)
05205 Proteoglycans in cancer
100458733 (SOS1)
05207 Chemical carcinogenesis - receptor activation
100458733 (SOS1)
05208 Chemical carcinogenesis - reactive oxygen species
100458733 (SOS1)
05231 Choline metabolism in cancer
100458733 (SOS1)
09162 Cancer: specific types
05210 Colorectal cancer
100458733 (SOS1)
05225 Hepatocellular carcinoma
100458733 (SOS1)
05226 Gastric cancer
100458733 (SOS1)
05214 Glioma
100458733 (SOS1)
05221 Acute myeloid leukemia
100458733 (SOS1)
05220 Chronic myeloid leukemia
100458733 (SOS1)
05211 Renal cell carcinoma
100458733 (SOS1)
05215 Prostate cancer
100458733 (SOS1)
05213 Endometrial cancer
100458733 (SOS1)
05224 Breast cancer
100458733 (SOS1)
05223 Non-small cell lung cancer
100458733 (SOS1)
09172 Infectious disease: viral
05161 Hepatitis B
100458733 (SOS1)
05160 Hepatitis C
100458733 (SOS1)
05163 Human cytomegalovirus infection
100458733 (SOS1)
05165 Human papillomavirus infection
100458733 (SOS1)
09165 Substance dependence
05034 Alcoholism
100458733 (SOS1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100458733 (SOS1)
01522 Endocrine resistance
100458733 (SOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_10
PH_19
IQ_SEC7_PH
RHG20_PH
Takusan
Motif
Other DBs
NCBI-GeneID:
100458733
NCBI-ProteinID:
XP_024098134
Ensembl:
ENSPPYG00000012474
UniProt:
A0A2J8SWK9
LinkDB
All DBs
Position
12:93521801..93665012
Genome browser
AA seq
1333 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINVLSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDRFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTNEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDAYLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSNDTVFIQVTLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISD
RTSVSDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccctacgagtttttcagcgaagagaacgcgcccaagtggcgg
ggactgctggtgcctgcgctgaaaaaggtccaggggcaagttcatcctactctcgagtct
aatgacgatgctcttcagtatgttgaagaattaattttgcaattattaaatatgctatgc
caagctcagccccgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccaattgataaatgggcaatagctgatgcccaatcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtcttagaatacatttctgcagac
attttaaagctggttgggaattacgtaagaaatatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgacaaggtattgatggatatgtttcatcaagatgta
gaagatattaatgtattatctttaactgatgaagagccttccacctcaggagaacaaact
tactatgatttggtaaaagcatttatggcagaaattcgacaatatataagggaactaaat
ctaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgcatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatacagtagaaatgacagatgaaggcagtccccatccactagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcgtatgctcga
gatattttgcgacctggttttcatgatcgtttccttagtcagttatcaaagcctggggca
gcactttatttgcagtcaataggcgaaggtttcaaagaagctgttcaatacgttttaccc
aggctgcttctggcccctgtttaccactgtctccattactttgaacttttgaagcagtta
gaagaaaaaagtgaagatcaagaagacaaggaatgtttaaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggttgggagggaaaagacattggacagtgt
tgcaatgaatttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcaaatcatgggcagccaagactt
cctggtgctagcaatgcagaatatcgtcttaaagaaaagttttttatgcgaaaggtacaa
attaatgataaagatgacaccaatgaatacaaacatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtaacaatgctacag
gaagagaaagaggagcagatgaggctgcctagtgccgatgtttatagatttgcagagcct
gactctgaagagaatattatatttgaagagaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggcttacgtaccatatgtacgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgcaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaagatttagaaaagaa
tatatacagcctgtgcaactgcgagtattaaatgtatgtcggcactgggtagagcaccac
ttctatgattttgaaagagatgcatatcttttgcaacgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggttgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaactcactttacttgaatcagatctataccgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaactctcctaat
cttctgaaaatgattcgacataccaccaacctcactctgtggtttgagaaatgtattgta
gaaactgaaaatttagaagaaagagtagctgtggtgagtcgaataattgagattctacaa
gtctttcaagagttgaacaactttaatggtgtccttgaggtcgtcagtgctatgaattca
tcacctgtttacagactagaccacacatttgagcaaataccaagtcgccagaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctcactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctaaaaagacatgggaaagagcttataaactttagcaaa
aggaggaaagtagcagaaataacaggagagatccagcagtaccaaaatcagccttactgt
ttacgagtagaatcagatatcaaaaggttctttgaaaacttgaatccgatgggaaatagc
atggagaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaac
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgaggcatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagaaagtacagcatctgcacca
aattctccaagaacaccgttaacacctccgcctgcttctggtgcttccagtaccacagat
gtttgcagtgtatttgattccgatcattcgagcccttttcactcaagcaatgataccgtc
tttatccaagttactctgccccatggcccaagatctgcttctgtatcatctataagttta
accaaaggcactgatgaagtgcctgtccctcctcctgttcctccacgaagacgaccagaa
tctgccccagcagaatcttcaccatctaagattatgtctaagcatttggacagtccccca
gccattcctcctaggcaacccacatcaaaagcctattcaccacgatattcaatatcagac
cggacctctgtctcagaccctcctgaaagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttccccttttacaccacctcct
cctcaaacaccttctcctcacggcacaagaaggcatctgccatcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcaa
catatccctaaactccctccaaaaacttacaaaagggagcacacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga
DBGET
integrated database retrieval system
