| Entry |
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| Symbol |
SCN5A
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| Name |
(RefSeq) sodium channel protein type 5 subunit alpha
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| KO |
| K04838 | voltage-gated sodium channel type V alpha |
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| Organism |
pon Pongo abelii (Sumatran orangutan)
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| Pathway |
| pon04261 | Adrenergic signaling in cardiomyocytes |
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| Brite |
KEGG Orthology (KO) [BR:pon00001]
09150 Organismal Systems
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100459117 (SCN5A)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:pon04040]
100459117 (SCN5A)
Ion channels [BR:pon04040]
Voltage-gated cation channels
Sodium channel, voltage-gated (Nav)
100459117 (SCN5A)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
2:115863477..115966594
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| AA seq |
2091 aa
MANFLLPRGTSSFRRFTRESLAAIEKRMVEKQARGSTTLQESREGLPEEEAPRPQLDLQA
SKKLPDLYGNPPRELIGEPLEDLDPFYSTQKTFIVLNKGKTIFRFSATNALYVLSPFHPI
RRAAVKILVHSLFSMLIMCTILTNCVFMAQHDPPPWTKYVEYTFTAIYTFESLVKILARG
FCLHAFTFLRDPWNWLDFSVIVMAYVSENIKLGNLSALRTFRVLRALKTISVIPGKMPRF
ASQISATSDSLSVFPTPFPPLCVSYYRVVIVSCVNFPCYRYTTEFVDLGNVSALRTFRVL
RALKTISVISGLKTIVGALIQSVKKLADVMVLTVFCLSVFALIGLQLFMGNLRHKCVRNF
TALNGTNGSVEADGLVWESLDLYLSDPENYLLKNGTSDVLLCGNSSDAGTCPEGYRCLKA
GENPDHGYTSFDSFAWAFLALFRLMTQDCWERLYQQTLRSAGKIYMIFFMLVIFLGSFYL
VNLILAVVAMAYEEQNQATIAETEEKEKRFQEAMEMLKKEHEALTIRGVDTVSRSSLEMS
PLAPVNSHERRRKRRKRMSSGTEECGEDRFPKSDSEDGPRAMNHLSLTHGLSRTSMKPRS
SRGSIFTFRRRDLGSEADFADDENSTAGESESHHISLLVPWPLRRTSAQGQPSPGTSAPG
HALNGKKNSTVDCNGVVSLLGAGDLEATSPGSHLLHPVMLEHPPDTTTPSEEPGGPQMLT
SQAPCVDGFEEPGARQRALSAVSVLTSALEELEESRRKCPPCWNRLAQRYLIWECCPLWM
SIKQGVKLVVMDPFTDLTITMCIVLNTLFMALEHYNMTSEFEEMLQVGNLVFTGIFTAEM
TFKIIALDPYYYFQQGWNIFDSIIVILSLMELGLSRMSNLSVLRSFRLLRVFKLAKSWPT
LNTLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKNYSELRDSDSGLLPRWHMMDF
FHAFLIIFRILCGEWIETMWDCMEVSGQSLCLLVFLLVMVIGNLVVLNLFLALLLSSFSA
DNLTAPDEDRELNNLQLALARIQRGLRFVKRTTWDFCCGLLRQRPQKPAALAAQGQLPSC
IATPYSPPPPETEKAPPTRKETRFEESKQPGQGTPGDPEPVCVPIAVAESDTDDQEEDEE
NSLGTEESSKQQESQPVSGGPEAPPDSRTWSQVSATASSEAEASASQADRRQQRKAEPQA
PGCGETPEDSCSEGSTADMTNTAELLEQIPDLGQDVKDPEDCFTEGCVRRCPCCAVDTTQ
APGKVWWQLRKTCYHIVEHSWFETFIIFMILLSSGALAFEDIYLEERKTIKVLLEYADKM
FTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLIVDVSLISLVANTLGFAEMGPIKSLRTL
RALRPLRALSRFEGMRVVVNALVGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFGRCIN
QTEGDLPLNYTIVNNKSQCESLNMTGELYWTKVKVNFDNVGAGYLALLQVATFKGWMDIM
YAAVDSRGYEEQPQWEYNLYMYIYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKLGGQDI
FMTEEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGFIFDIVTKQAFDVTIMFLICLNMVTM
MVETDDQSPEKINILAKINLLFVAIFTGECIVKLAALRHYYFTNSWNIFDFVVVILSIVG
TVLSDIIQKYFFSPTLFRVIRLARIGRILRLIRGAKGIRTLLFALMMSLPALFNIGLLLF
LVMFIYSIFGMANFAYVKWEAGIDDMFNFQTFANSMLCLFQITTSAGWDGLLSPILNTGP
PYCDPTLPNSNGSRGDCGSPAVGILFFTTYIIISFLIVVNMYIAIILENFSVATEESTEP
LSEDDFDMFYEIWEKFDPEATQFIEYSVLSDFADALSEPLRIAKPNQISLINMDLPMVSG
DRIHCMDILFAFTKRVLGESGEMDALKIQMEEKFMAANPSKISYEPITTTLRRKHEEVSA
TVIQRAFRRHLLQRSLKHASFLFRQQAGRGLSEEDAPEQEGLIAYVMSENFSRPLGPPSS
SSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFTPSPDRDRESTV |
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| NT seq |
6276 nt +upstreamnt +downstreamnt
atggcaaacttcctgttacctcggggcaccagcagcttccgcaggttcacacgggagtcc
ctggcagccattgagaagcgcatggtggagaagcaagcccgcggctcaaccaccttgcag
gagagccgagaggggctgcctgaggaggaggctccccggccccagctggacctgcaggcc
tctaaaaagctgccagatctctatggcaatccaccccgagagctcatcggagagcccctg
gaggacctggaccccttctatagcacccaaaagactttcatcgtactgaataaaggcaag
accatcttccggttcagtgccaccaacgccttgtatgtcctcagtcccttccaccccatc
cggagagcagctgtgaagattctggttcactcgctcttcagcatgctcatcatgtgcacc
atcctcaccaactgcgtgttcatggcccagcacgaccctccaccctggaccaagtatgtc
gagtacaccttcaccgccatttacacctttgagtctctggtcaagattctggctcgaggc
ttctgcctgcatgcgttcactttccttcgggacccatggaactggctggacttcagtgtg
attgtcatggcgtatgtatcagaaaatataaaactaggcaatttgtcggctcttcgaact
ttcagagtcctgagagctctaaaaactatttcagttatcccaggtaagatgcccaggttt
gcctctcagatctcagctacaagtgactctctctctgtcttccccaccccctttcctcct
ctgtgtgtctcctattatcgtgttgtcattgtctcgtgtgtgaatttcccttgttacaga
tacacaactgaatttgtggacctgggcaatgtctcagccttacgcaccttccgagtcctc
cgggccctgaaaactatatcagtcatttcagggctgaagaccatcgtgggggccctgatc
cagtctgtgaagaagctggctgatgtgatggtcctcacagtcttctgcctcagcgtcttt
gccctcataggcctgcagctcttcatgggcaacctaaggcacaagtgcgtgcgcaacttc
acggcgctcaatggcaccaacggctccgtggaggccgacggcttggtctgggaatccctg
gacctttacctcagtgatccagaaaattacctgctcaagaatggcacctctgacgtgtta
ctgtgtgggaacagctctgacgctgggacatgtcctgagggctaccggtgcctaaaggca
ggtgagaaccctgaccacggctacaccagcttcgattcctttgcctgggcctttcttgca
ctcttccgcctgatgacgcaggactgctgggagcgcctctatcagcagaccctcaggtcc
gcagggaagatctacatgatcttcttcatgcttgtcatcttcctggggtccttctacctg
gtgaacctgatcctcgccgtggtcgccatggcctatgaggagcaaaaccaagccaccatc
gctgagactgaggagaaggaaaagcgcttccaggaggccatggaaatgctcaagaaagaa
cacgaggccctcaccatcaggggtgtggataccgtgtcccgtagctccttggagatgtcc
cctttggccccagtaaacagccacgagagaagaaggaagaggagaaaacggatgtcttca
ggaactgaggaatgtggggaggacaggttccccaagtctgactcagaagatggtcccaga
gcaatgaatcatctcagcctcacccatggcctcagcagaacttctatgaagccacgttcc
agccgcgggagcattttcacctttcgccggcgagacctgggttctgaagcagattttgca
gatgatgaaaacagcacagcgggggagagcgagagccaccacatatcactgctggtgccc
tggcccctgcgccggaccagtgcccagggacagcccagtcccggaacctcggctcctggc
cacgccctcaatggcaaaaagaacagcactgtggactgcaatggggtggtctcattactg
ggggcaggcgacctagaggccacatccccaggaagccacctcctccaccctgtgatgcta
gaacacccaccagacacgaccacgccatcggaggagccaggcgggccccagatgctgacc
tcccaggctccgtgtgtagatggcttcgaggagccaggagcacggcagcgggccctcagc
gcagtcagtgtcctcaccagcgcactggaagagttagaggagtctcgccgcaagtgtcct
ccatgctggaaccgccttgcccagcgctacctgatctgggagtgctgcccgctgtggatg
tccatcaagcagggagtgaagttggtggtcatggacccgtttactgacctcaccatcact
atgtgcatcgtgctcaacacactcttcatggcgctggagcactacaacatgacaagtgaa
ttcgaggagatgctgcaggtcggaaacctggtcttcacagggatcttcacagcagagatg
accttcaagatcattgccctcgacccctactactacttccaacagggctggaacatcttc
gacagcatcatcgtcatccttagcctcatggagctgggcctgtcccgcatgagcaacttg
tcggtgctgcgctccttccgcctgctgcgggtcttcaagctggccaaatcgtggcccacc
ctgaacacactcatcaagatcatcgggaactcagtgggggcactggggaacctgacactg
gtgctagccatcatcgtgttcatctttgctgtggtgggcatgcagctctttggcaagaac
tactcagagctgagggacagcgactcaggcctgctgcctcgctggcacatgatggacttc
tttcatgccttcctcatcatcttccgcatcctctgtggagagtggatcgagaccatgtgg
gactgcatggaggtgtctgggcagtcattatgcctgctggtcttcttgcttgttatggtc
attggcaaccttgtggtcctgaatctcttcctggccttgctgctcagctccttcagtgca
gacaacctcacagcccctgatgaggacagagagctgaacaacctccagctggccctggcc
cgcatccagaggggactgcgctttgtcaagcggaccacctgggatttctgctgtggtctc
ctgcggcagcggcctcagaagcctgcagcccttgccgctcagggccagctgcccagctgc
attgccaccccctactccccaccacccccagagacggagaaggcgcctcccacccgcaag
gaaacacggtttgaggaaagcaagcaaccgggccagggcacccctggggatccagagccc
gtgtgtgtgcccatcgctgtggccgagtcagacacagatgaccaagaagaggatgaggag
aacagcctgggcacggaggagtccagcaagcagcaggaatcccagcctgtgtccggtggc
ccagaggcccctccggattccaggacctggagccaggtgtcagcaactgcctcctctgag
gctgaggccagtgcatctcaggctgaccggcggcagcagcggaaagcggaaccccaggcc
ccagggtgcggtgagaccccagaggacagttgctccgagggcagcacagcagacatgacc
aacaccgctgagctcctggagcagatccccgacctcggccaggatgtcaaggatccagag
gactgcttcaccgaaggctgtgtccggcgctgtccctgctgtgcagtggacaccacacag
gccccagggaaggtctggtggcagttgcgcaagacctgctaccacatcgtggagcacagc
tggttcgagacattcatcatcttcatgatcttactcagcagtggagcgctggccttcgag
gacatctacctagaggagcggaagaccatcaaggttctgcttgaatatgctgacaagatg
ttcacctatgtcttcgtgctggagatgctgctcaagtgggtggcctacggcttcaagaag
tacttcaccaatgcctggtgctggctcgacttcctcatcgtggacgtctctctgatcagc
ctggtggccaacaccctgggctttgccgagatgggccccatcaagtcactgcggacgctg
cgtgcactccgccccctgagagctctgtcacgatttgagggcatgagggtggttgtcaat
gccctggtgggcgccatcccgtccatcatgaacgtcctcctcgtctgcctcatcttctgg
ctcatcttcagcatcatgggcgtgaacctcttcgcggggaagtttgggaggtgcatcaac
cagacagagggagacttgcctttgaactacaccatcgtgaacaacaagagccagtgtgag
tccttgaacatgaccggagaattgtactggaccaaggtgaaagtcaactttgacaacgtg
ggggccgggtacctggcccttctgcaggtggcaacatttaaaggctggatggacattatg
tatgcagctgtggactccagggggtatgaagagcagcctcagtgggaatacaacctctac
atgtacatctattttgtcattttcatcatcttcgggtctttcttcaccctgaacctcttt
atcggtgtcatcattgacaacttcaaccaacagaagaaaaagttagggggccaggacatc
ttcatgacagaggagcagaagaagtactacaatgccatgaagaagctgggctccaagaag
ccccagaagcccatcccacggccactgaacaagtaccagggcttcatattcgacattgtg
accaagcaggcctttgatgtcaccatcatgtttctgatctgcttgaatatggtgaccatg
atggtggagacagatgaccaaagtcccgagaaaatcaacatcttggccaagatcaacctg
ctctttgtggccatcttcacaggcgagtgtattgtcaagctggctgccctgcgccactat
tacttcaccaacagctggaatatcttcgacttcgtggttgtcatcctctccatcgtgggc
actgtgctctcggacatcatccagaagtacttcttctccccaacgctcttccgagtcatc
cgcctggcccgaatcggccgcatcctcagactgatccgaggggccaaggggatccgcacg
ctgctctttgccctcatgatgtccctgcctgccctcttcaacatcgggctgctgctcttc
ctcgtcatgttcatctactccatctttggcatggccaacttcgcttatgtcaagtgggag
gctggcatcgatgacatgttcaacttccagaccttcgccaacagcatgctgtgcctcttc
cagatcaccacgtcagccggctgggatggcctcctcagccccatcctcaacactgggccg
ccctactgcgaccccactctgcccaacagcaatggctctcggggtgactgtgggagccca
gctgtgggcatcctcttcttcaccacctacatcatcatctccttcctcatcgtggtcaac
atgtacattgccatcatcctggagaacttcagcgtggccacggaggagagcaccgagccc
ctgagtgaggacgacttcgatatgttctatgagatctgggagaagtttgacccagaggcc
actcagtttattgagtattcggtcctgtctgactttgccgatgccctgtctgagccactc
cgtatcgccaagcccaaccagataagcctcatcaacatggacctgcccatggtgagtggg
gaccgcatccattgcatggacatcctctttgccttcaccaaaagggtcctgggggagtct
ggggagatggacgccctgaagatccagatggaggagaagttcatggcagccaacccatcc
aagatctcctacgagcccatcaccaccacactccggcgcaagcacgaagaggtgtcggcc
acggttatccagagggccttccgcaggcacctgctgcaacgctctttgaagcatgcctcc
ttcctcttccgtcagcaggcgggcaggggcctctccgaagaggatgcccctgagcaagag
ggcctcatcgcctatgtgatgagtgagaacttctcccgaccccttggcccaccctccagc
tcctccatctcctccacttccttcccaccctcctatgacagtgtcactagagccaccagc
gataacctccaggtgcgggggtctgactacagccacagcgaagatctcgccgacttcacc
ccgtctccggacagggaccgtgagtccactgtgtga |
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