Pongo abelii (Sumatran orangutan): 100459427 Help Entry 100459427         CDS       T01416                                  Symbol HRAS Name (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01521   EGFR tyrosine kinase inhibitor resistance pon01522   Endocrine resistance pon04010   MAPK signaling pathway pon04012   ErbB signaling pathway pon04014   Ras signaling pathway pon04015   Rap1 signaling pathway pon04062   Chemokine signaling pathway pon04068   FoxO signaling pathway pon04071   Sphingolipid signaling pathway pon04072   Phospholipase D signaling pathway pon04137   Mitophagy - animal pon04140   Autophagy - animal pon04144   Endocytosis pon04150   mTOR signaling pathway pon04151   PI3K-Akt signaling pathway pon04210   Apoptosis pon04211   Longevity regulating pathway pon04213   Longevity regulating pathway - multiple species pon04218   Cellular senescence pon04360   Axon guidance pon04370   VEGF signaling pathway pon04371   Apelin signaling pathway pon04510   Focal adhesion pon04540   Gap junction pon04550   Signaling pathways regulating pluripotency of stem cells pon04625   C-type lectin receptor signaling pathway pon04630   JAK-STAT signaling pathway pon04650   Natural killer cell mediated cytotoxicity pon04660   T cell receptor signaling pathway pon04662   B cell receptor signaling pathway pon04664   Fc epsilon RI signaling pathway pon04714   Thermogenesis pon04720   Long-term potentiation pon04722   Neurotrophin signaling pathway pon04725   Cholinergic synapse pon04726   Serotonergic synapse pon04730   Long-term depression pon04810   Regulation of actin cytoskeleton pon04910   Insulin signaling pathway pon04912   GnRH signaling pathway pon04915   Estrogen signaling pathway pon04916   Melanogenesis pon04917   Prolactin signaling pathway pon04919   Thyroid hormone signaling pathway pon04921   Oxytocin signaling pathway pon04926   Relaxin signaling pathway pon04929   GnRH secretion pon04933   AGE-RAGE signaling pathway in diabetic complications pon04935   Growth hormone synthesis, secretion and action pon05010   Alzheimer disease pon05022   Pathways of neurodegeneration - multiple diseases pon05034   Alcoholism pon05132   Salmonella infection pon05160   Hepatitis C pon05161   Hepatitis B pon05163   Human cytomegalovirus infection pon05165   Human papillomavirus infection pon05166   Human T-cell leukemia virus 1 infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05170   Human immunodeficiency virus 1 infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05205   Proteoglycans in cancer pon05206   MicroRNAs in cancer pon05207   Chemical carcinogenesis - receptor activation pon05208   Chemical carcinogenesis - reactive oxygen species pon05210   Colorectal cancer pon05211   Renal cell carcinoma pon05213   Endometrial cancer pon05214   Glioma pon05215   Prostate cancer pon05216   Thyroid cancer pon05218   Melanoma pon05219   Bladder cancer pon05220   Chronic myeloid leukemia pon05221   Acute myeloid leukemia pon05223   Non-small cell lung cancer pon05224   Breast cancer pon05225   Hepatocellular carcinoma pon05226   Gastric cancer pon05230   Central carbon metabolism in cancer pon05231   Choline metabolism in cancer pon05235   PD-L1 expression and PD-1 checkpoint pathway in cancer pon05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100459427 (HRAS)    04012 ErbB signaling pathway     100459427 (HRAS)    04014 Ras signaling pathway     100459427 (HRAS)    04015 Rap1 signaling pathway     100459427 (HRAS)    04370 VEGF signaling pathway     100459427 (HRAS)    04371 Apelin signaling pathway     100459427 (HRAS)    04630 JAK-STAT signaling pathway     100459427 (HRAS)    04068 FoxO signaling pathway     100459427 (HRAS)    04072 Phospholipase D signaling pathway     100459427 (HRAS)    04071 Sphingolipid signaling pathway     100459427 (HRAS)    04151 PI3K-Akt signaling pathway     100459427 (HRAS)    04150 mTOR signaling pathway     100459427 (HRAS)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     100459427 (HRAS)    04140 Autophagy - animal     100459427 (HRAS)    04137 Mitophagy - animal     100459427 (HRAS)   09143 Cell growth and death    04210 Apoptosis     100459427 (HRAS)    04218 Cellular senescence     100459427 (HRAS)   09144 Cellular community - eukaryotes    04510 Focal adhesion     100459427 (HRAS)    04540 Gap junction     100459427 (HRAS)    04550 Signaling pathways regulating pluripotency of stem cells     100459427 (HRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     100459427 (HRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     100459427 (HRAS)    04650 Natural killer cell mediated cytotoxicity     100459427 (HRAS)    04660 T cell receptor signaling pathway     100459427 (HRAS)    04662 B cell receptor signaling pathway     100459427 (HRAS)    04664 Fc epsilon RI signaling pathway     100459427 (HRAS)    04062 Chemokine signaling pathway     100459427 (HRAS)   09152 Endocrine system    04910 Insulin signaling pathway     100459427 (HRAS)    04929 GnRH secretion     100459427 (HRAS)    04912 GnRH signaling pathway     100459427 (HRAS)    04915 Estrogen signaling pathway     100459427 (HRAS)    04917 Prolactin signaling pathway     100459427 (HRAS)    04921 Oxytocin signaling pathway     100459427 (HRAS)    04926 Relaxin signaling pathway     100459427 (HRAS)    04935 Growth hormone synthesis, secretion and action     100459427 (HRAS)    04919 Thyroid hormone signaling pathway     100459427 (HRAS)    04916 Melanogenesis     100459427 (HRAS)   09156 Nervous system    04725 Cholinergic synapse     100459427 (HRAS)    04726 Serotonergic synapse     100459427 (HRAS)    04720 Long-term potentiation     100459427 (HRAS)    04730 Long-term depression     100459427 (HRAS)    04722 Neurotrophin signaling pathway     100459427 (HRAS)   09158 Development and regeneration    04360 Axon guidance     100459427 (HRAS)   09149 Aging    04211 Longevity regulating pathway     100459427 (HRAS)    04213 Longevity regulating pathway - multiple species     100459427 (HRAS)   09159 Environmental adaptation    04714 Thermogenesis     100459427 (HRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100459427 (HRAS)    05206 MicroRNAs in cancer     100459427 (HRAS)    05205 Proteoglycans in cancer     100459427 (HRAS)    05207 Chemical carcinogenesis - receptor activation     100459427 (HRAS)    05208 Chemical carcinogenesis - reactive oxygen species     100459427 (HRAS)    05203 Viral carcinogenesis     100459427 (HRAS)    05230 Central carbon metabolism in cancer     100459427 (HRAS)    05231 Choline metabolism in cancer     100459427 (HRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100459427 (HRAS)   09162 Cancer: specific types    05210 Colorectal cancer     100459427 (HRAS)    05225 Hepatocellular carcinoma     100459427 (HRAS)    05226 Gastric cancer     100459427 (HRAS)    05214 Glioma     100459427 (HRAS)    05216 Thyroid cancer     100459427 (HRAS)    05221 Acute myeloid leukemia     100459427 (HRAS)    05220 Chronic myeloid leukemia     100459427 (HRAS)    05218 Melanoma     100459427 (HRAS)    05211 Renal cell carcinoma     100459427 (HRAS)    05219 Bladder cancer     100459427 (HRAS)    05215 Prostate cancer     100459427 (HRAS)    05213 Endometrial cancer     100459427 (HRAS)    05224 Breast cancer     100459427 (HRAS)    05223 Non-small cell lung cancer     100459427 (HRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100459427 (HRAS)    05170 Human immunodeficiency virus 1 infection     100459427 (HRAS)    05161 Hepatitis B     100459427 (HRAS)    05160 Hepatitis C     100459427 (HRAS)    05163 Human cytomegalovirus infection     100459427 (HRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     100459427 (HRAS)    05165 Human papillomavirus infection     100459427 (HRAS)   09171 Infectious disease: bacterial    05132 Salmonella infection     100459427 (HRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     100459427 (HRAS)    05022 Pathways of neurodegeneration - multiple diseases     100459427 (HRAS)   09165 Substance dependence    05034 Alcoholism     100459427 (HRAS)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100459427 (HRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100459427 (HRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100459427 (HRAS)    01522 Endocrine resistance     100459427 (HRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pon04131]     100459427 (HRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pon04147]     100459427 (HRAS)    04031 GTP-binding proteins [BR:pon04031]     100459427 (HRAS) Membrane trafficking [BR:pon04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     100459427 (HRAS)  Endocytosis   Macropinocytosis    Ras GTPases     100459427 (HRAS) Exosome [BR:pon04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    100459427 (HRAS)   Exosomal proteins of colorectal cancer cells    100459427 (HRAS) GTP-binding proteins [BR:pon04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     100459427 (HRAS) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N DUF6974 Motif Other DBs NCBI-GeneID:  100459427 NCBI-ProteinID:  XP_024111740 Ensembl:  ENSPPYG00000002868 UniProt:  A0A6D2X9G5 LinkDB All DBs Position 9:complement(421948..425318) Genome browser AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG CMSCKCVLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacggaatataagctcgtggtggtgggcgccggcggtgtgggcaagagtgcgctgacc atccagctgatccagaaccactttgtggacgaatacgaccccactatagaggactcctat cggaagcaggtggtcattgatggggagacatgcctgttggacatcctggacacggctggc caggaggagtacagcgccatgcgggaccagtacatgcgcactggggagggcttcctgtgt gtgtttgccatcaacaacaccaagtctttcgaggacatccaccagtacagggagcagatc aagcgggtgaaggactcggacgacgtgcccatggtgctggtggggaacaagtgtgacctg gctgcacgcaccgtggagtctcggcaggctcaagacctcgcccgaagctacggcatcccc tacatcgagacctcggccaagacccggcagggagtggaggatgccttctacacgttggtg cgtgagatccggcagcacaagctgcggaagctgaaccctcctgatgagagtggccccggc tgcatgagctgcaagtgtgtgctctcctga

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