KEGG   Pongo abelii (Sumatran orangutan): 100459799
Entry
100459799         CDS       T01416                                 
Symbol
PPP1CA
Name
(RefSeq) serine/threonine-protein phosphatase PP1-alpha catalytic subunit
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon03015  mRNA surveillance pathway
pon04022  cGMP-PKG signaling pathway
pon04024  cAMP signaling pathway
pon04114  Oocyte meiosis
pon04218  Cellular senescence
pon04261  Adrenergic signaling in cardiomyocytes
pon04270  Vascular smooth muscle contraction
pon04390  Hippo signaling pathway
pon04510  Focal adhesion
pon04611  Platelet activation
pon04720  Long-term potentiation
pon04728  Dopaminergic synapse
pon04750  Inflammatory mediator regulation of TRP channels
pon04810  Regulation of actin cytoskeleton
pon04910  Insulin signaling pathway
pon04921  Oxytocin signaling pathway
pon04931  Insulin resistance
pon05031  Amphetamine addiction
pon05034  Alcoholism
pon05168  Herpes simplex virus 1 infection
pon05205  Proteoglycans in cancer
pon05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pon00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    100459799 (PPP1CA)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    100459799 (PPP1CA)
   04024 cAMP signaling pathway
    100459799 (PPP1CA)
   04022 cGMP-PKG signaling pathway
    100459799 (PPP1CA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100459799 (PPP1CA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    100459799 (PPP1CA)
  09156 Nervous system
   04728 Dopaminergic synapse
    100459799 (PPP1CA)
   04720 Long-term potentiation
    100459799 (PPP1CA)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100459799 (PPP1CA)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100459799 (PPP1CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    100459799 (PPP1CA)
   05034 Alcoholism
    100459799 (PPP1CA)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100459799 (PPP1CA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    100459799 (PPP1CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:pon01009]
    100459799 (PPP1CA)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:pon03021]
    100459799 (PPP1CA)
   03019 Messenger RNA biogenesis [BR:pon03019]
    100459799 (PPP1CA)
   03041 Spliceosome [BR:pon03041]
    100459799 (PPP1CA)
Enzymes [BR:pon01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100459799 (PPP1CA)
Protein phosphatases and associated proteins [BR:pon01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100459799 (PPP1CA)
Transcription machinery [BR:pon03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100459799 (PPP1CA)
Messenger RNA biogenesis [BR:pon03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     100459799 (PPP1CA)
Spliceosome [BR:pon03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100459799 (PPP1CA)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 100459799
NCBI-ProteinID: XP_002821493
Ensembl: ENSPPYG00000002995
UniProt: A0A6D2XD44
LinkDB
Position
9:7250643..7254340
AA seq 330 aa
MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLK
ICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFL
LRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDL
QSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHD
LDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAD
KNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtccgacagcgagaagctcaacctggactcgatcatcgggcgcctgctggaagtgcag
ggctcgcggcctggcaagaatgtacagctgacagagaacgagatccgcggtctgtgcttg
aaatcccgggagattttcctgagccagcccattcttctggagctggaggcacccctcaag
atctgcggtgacatacacggccagtactacgaccttctgcgactatttgagtatggcggt
ttccctcccgagagcaactacctctttctgggggactatgtggacaggggcaagcagtcc
ttggagaccatctgcctgctgctggcgtataagatcaagtaccccgagaacttcttcttg
ctccgtgggaaccacgagtgtgccagcatcaaccgcatctatggtttctacgatgagtgc
aagagacgctacaacatcaaactgtggaaaaccttcactgactgcttcaactgcctgccc
atcgcagccatagtggacgaaaagatcttctgctgccacggaggcctgtccccggacctg
cagtctatggagcagattcggcggatcatgcggcccacagatgtgcctgaccagggcctg
ctgtgtgacctgctgtggtctgaccctgacaaggacgtgcagggctggggcgagaacgac
cgtggcgtctcttttacctttggagccgaggtggtggccaagttcctccacaagcacgac
ttggacctcatctgccgagcacaccaggtggtagaagatggctatgagttctttgccaag
cggcagctggtgacacttttctcagctcccaactactgtggcgagtttgacaatgctggc
gccatgatgagcgtggacgagaccctcatgtgctccttccagatcctcaagcccgccgac
aagaacaaggggaagtacgggcagttcagtggcctgaaccctggaggccgacccatcacc
ccaccccgcaattccgccaaagccaagaaatag

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