Pongo abelii (Sumatran orangutan): 100460806 Help Entry 100460806         CDS       T01416                                  Symbol ADCY4 Name (RefSeq) adenylate cyclase type 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon00230   Purine metabolism pon01100   Metabolic pathways pon01522   Endocrine resistance pon04015   Rap1 signaling pathway pon04020   Calcium signaling pathway pon04022   cGMP-PKG signaling pathway pon04024   cAMP signaling pathway pon04062   Chemokine signaling pathway pon04072   Phospholipase D signaling pathway pon04081   Hormone signaling pon04082   Neuroactive ligand signaling pon04114   Oocyte meiosis pon04211   Longevity regulating pathway pon04213   Longevity regulating pathway - multiple species pon04261   Adrenergic signaling in cardiomyocytes pon04270   Vascular smooth muscle contraction pon04371   Apelin signaling pathway pon04540   Gap junction pon04611   Platelet activation pon04713   Circadian entrainment pon04714   Thermogenesis pon04723   Retrograde endocannabinoid signaling pon04724   Glutamatergic synapse pon04725   Cholinergic synapse pon04727   GABAergic synapse pon04742   Taste transduction pon04750   Inflammatory mediator regulation of TRP channels pon04911   Insulin secretion pon04912   GnRH signaling pathway pon04913   Ovarian steroidogenesis pon04914   Progesterone-mediated oocyte maturation pon04915   Estrogen signaling pathway pon04916   Melanogenesis pon04918   Thyroid hormone synthesis pon04921   Oxytocin signaling pathway pon04923   Regulation of lipolysis in adipocytes pon04925   Aldosterone synthesis and secretion pon04926   Relaxin signaling pathway pon04927   Cortisol synthesis and secretion pon04928   Parathyroid hormone synthesis, secretion and action pon04934   Cushing syndrome pon04935   Growth hormone synthesis, secretion and action pon04970   Salivary secretion pon04971   Gastric acid secretion pon04972   Pancreatic secretion pon04976   Bile secretion pon05032   Morphine addiction pon05163   Human cytomegalovirus infection pon05166   Human T-cell leukemia virus 1 infection pon05200   Pathways in cancer pon05207   Chemical carcinogenesis - receptor activation pon05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pon00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     100460806 (ADCY4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     100460806 (ADCY4)    04371 Apelin signaling pathway     100460806 (ADCY4)    04020 Calcium signaling pathway     100460806 (ADCY4)    04072 Phospholipase D signaling pathway     100460806 (ADCY4)    04024 cAMP signaling pathway     100460806 (ADCY4)    04022 cGMP-PKG signaling pathway     100460806 (ADCY4)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     100460806 (ADCY4)    04081 Hormone signaling     100460806 (ADCY4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     100460806 (ADCY4)   09144 Cellular community - eukaryotes    04540 Gap junction     100460806 (ADCY4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     100460806 (ADCY4)    04062 Chemokine signaling pathway     100460806 (ADCY4)   09152 Endocrine system    04911 Insulin secretion     100460806 (ADCY4)    04923 Regulation of lipolysis in adipocytes     100460806 (ADCY4)    04912 GnRH signaling pathway     100460806 (ADCY4)    04913 Ovarian steroidogenesis     100460806 (ADCY4)    04915 Estrogen signaling pathway     100460806 (ADCY4)    04914 Progesterone-mediated oocyte maturation     100460806 (ADCY4)    04921 Oxytocin signaling pathway     100460806 (ADCY4)    04926 Relaxin signaling pathway     100460806 (ADCY4)    04935 Growth hormone synthesis, secretion and action     100460806 (ADCY4)    04918 Thyroid hormone synthesis     100460806 (ADCY4)    04928 Parathyroid hormone synthesis, secretion and action     100460806 (ADCY4)    04916 Melanogenesis     100460806 (ADCY4)    04925 Aldosterone synthesis and secretion     100460806 (ADCY4)    04927 Cortisol synthesis and secretion     100460806 (ADCY4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100460806 (ADCY4)    04270 Vascular smooth muscle contraction     100460806 (ADCY4)   09154 Digestive system    04970 Salivary secretion     100460806 (ADCY4)    04971 Gastric acid secretion     100460806 (ADCY4)    04972 Pancreatic secretion     100460806 (ADCY4)    04976 Bile secretion     100460806 (ADCY4)   09156 Nervous system    04724 Glutamatergic synapse     100460806 (ADCY4)    04727 GABAergic synapse     100460806 (ADCY4)    04725 Cholinergic synapse     100460806 (ADCY4)    04723 Retrograde endocannabinoid signaling     100460806 (ADCY4)   09157 Sensory system    04742 Taste transduction     100460806 (ADCY4)    04750 Inflammatory mediator regulation of TRP channels     100460806 (ADCY4)   09149 Aging    04211 Longevity regulating pathway     100460806 (ADCY4)    04213 Longevity regulating pathway - multiple species     100460806 (ADCY4)   09159 Environmental adaptation    04713 Circadian entrainment     100460806 (ADCY4)    04714 Thermogenesis     100460806 (ADCY4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100460806 (ADCY4)    05207 Chemical carcinogenesis - receptor activation     100460806 (ADCY4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     100460806 (ADCY4)    05163 Human cytomegalovirus infection     100460806 (ADCY4)   09165 Substance dependence    05032 Morphine addiction     100460806 (ADCY4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     100460806 (ADCY4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     100460806 (ADCY4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     100460806 (ADCY4) Enzymes [BR:pon01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      100460806 (ADCY4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N CD52 Motif Other DBs NCBI-GeneID:  100460806 NCBI-ProteinID:  XP_009247256 Ensembl:  ENSPPYG00000005702 LinkDB All DBs Position 15:complement(27859677..27875358) Genome browser AA seq 1077 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPS FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV SYFLFVIFTAYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGLKMRPSLLMTR YLESWGAAKPFAHLSHGDSPVSTSTPLPEKTLASFSPQWSLDRSRTPRGLDDELDTGDAK FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI IQMLVTNRPPALAITYSITFLLFLLILFVCFSEDLMRCVLKGPKMLHWLPALSGLVATRP GLRIALGTATILLVFAMAITSLFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPY SMHCCTLGFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSECLIVRLYLGPLDS RPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRL LLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLR LLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMV EFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMEST GVLGKIQVTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGPPSATLG NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagcccccggccgccccccagcgaagacctcttctacgagacctac tacagcctgagccagcagtacccgctgctgctgctgctgctggggatcgtgctctgtgcg ctcgcggcgctgctcgccgtggcctgggccagcggcagggagctgacctcagacccgagc ttcctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc cgcgagcagcgactgcagcgctggacgcgtcccctgtccggcttggtatgggtcgcgctg ctagcgctaggccacgcctttctgttcaccgggggcgtggtgagcgcctgggaccaggtg tcctattttctcttcgtcatcttcacggcgtatgccatgctgcctttgggcatgcgggac gccgccgtcgcgggcctcgcctcctcactctcgcatctgctggtcctcgggctgtatctt gggccacagccggactcacggcctgcactgctgccgcagttggcagcaaacgcggtgctg ttcctgtgcgggaacgtggcaggagcgtaccacaaggcgctgatggagcgcgccctgcgg gccacgttccgggaggcactcagctccctgcactcacgccggcggctggacaccgagaag aagcaccaggaacaccttctcttatccatccttcctgcctacctggcccgagagatgaag gcagagatcatggcacggctgcaggcaggacaggggtcacggccagagagcaccaacaat ttccacagcctctatgtcaagaggcaccagggagtcagcgtgctgtatgctgacatcgtg ggcttcacacggctggccagcgagtgttcccctaaggagctggtgctcatgctcaatgag ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg ggggactgttactactgtgtctccgggctgccactctcactgccagaccatgccatcaac tgcgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggc gtggacatcaacatgcgtgtgggcgtgcactcaggcagcgtactgtgtggagtcatcggg ctgcagaagtggcagtacgacgtttggtcccatgatgtcacactggctaaccacatggag gcaggcggtgtaccagggcgagtgcacatcacaggggctaccctggccctgctggcaggg gcttatgctgtggaggacgcaggcatggagcatcgggacccttaccttcgggagctaggg gagcctacctatctggtcatcgatccacgggcagaggaggaggatgagaagggcactgca ggaggcttgctgtcctcgcttgagggcctcaagatgcgtccatcactgctgatgacccgt tacctggagtcctggggcgcagccaagccttttgcccacctgagccacggagacagccct gtgtccacctccacccctctcccggagaagaccctggcttccttcagcccccagtggagc ctggatcggagccgtaccccccggggactagatgatgaactggacaccggggatgccaag ttcttccaggtcattgagcagctcaactcgcagaaacagtggaagcagtcgaaggacttc aacccactgacactgtacttcagagagaaggagatggagaaagagtaccgactctctgca atccccgccttcaaatactatgaagcttgcaccttcctggtttttctctccaacttcatc atccagatgctagtgacaaacaggcccccagctctggcgatcacgtatagcatcaccttc ctcctcttcctcctcatcctttttgtctgcttctcagaggacctgatgaggtgtgtcctg aaaggccccaagatgctgcactggctgcctgcactgtctggcctggtggccacacgacca ggactgagaatagccttgggcaccgccaccatcctccttgtctttgccatggccattacc agcctgttcttcttcccaacatcatcagactgccctttccaagctcccaatgtgtcctcc atgatttccaacctctcctgggagctccctgggtctctgcctctcatcagtgtcccatac tccatgcactgctgcacactgggcttcctctcctgctccctgtttctgcacatgagcttc gagctgaagctgctgctgctcctgctgtggctggcggcatcctgctccctcttcctgcac tcccacgcctggctgtctgaatgtctcatcgtccgcctctatctgggccccttggactcc aggcccggagtgctgaaggagcccaaactgatgggtgctatctccttcttcatcttcttc ttcaccctccttgtcctggctcgccagaatgagtactactgccgcctggacttcctgtgg aagaagaagctgaggcaggagcgggaggagacagagacgatggagaacctgactcggctg ctcttggagaacgtgctccctgcacacgtggccccccagttcattggccagaaccggcgc aacgaggatctctaccaccagtcctacgaatgcgtttgtgtcctcttcgcctcagtccca gacttcaaggagttctactctgaatccaacatcaatcatgagggcctagagtgtctgagg ctgctcaatgagataattgctgattttgatgagctgctctccaagcccaagttcagtggg gtggagaagatcaagaccatcggcagcacctacatggcagccacaggcttaaatgccacc tctggacaggatgcacaacaggatgctgaacggagctgcagccaccttggcactatggtg gaatttgccgtggccctggggtctaagctggacgtcatcaacaagcattcattcaacaac ttccgcctgcgtgtggggttgaaccatggaccagtagtagctggagttattggggcccag aagccgcaatatgacatttggggcaacacagtgaacgtggccagccgcatggagagtaca ggagtccttggcaaaatccaagtgactgaggagacagcatgggccctacagtccctgggc tacacctgctacagccggggtgtcatcaaggtgaaaggcaaagggcagctctgcacctac ttcctgaacacagacttgacacgaactggacctccttcagctaccctaggctga

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