| Entry |
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|---|
| Symbol |
UBR4
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| Name |
(RefSeq) E3 ubiquitin-protein ligase UBR4 isoform X1
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| KO |
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|---|
| Organism |
pon Pongo abelii (Sumatran orangutan)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:pon00001]
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
100461681 (UBR4)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100461681 (UBR4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:pon04121]
100461681 (UBR4)
Enzymes [BR:pon01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100461681 (UBR4)
Ubiquitin system [BR:pon04121]
Ubiquitin ligases (E3)
Single Ring-finger type E3
UBR box proteins
100461681 (UBR4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:214345716..214481926
|
|---|
| AA seq |
5212 aa
MATSGGEEAAAAAPAPGTPATGADTTPGWEVAVRPLLSASYSAFEMKELPQLVASVIESE
SEILHHEKQYEPFYSSFVALSTHYITTVCSLIPRNQLQSVAAACKVLIEFSLLRLENPDE
ACAVSQKHLILLIKGLCTGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKELASPV
SPELRQKEVQMNFLNQLTSVFNPRTVASQPISTQTLVEGENDEQSSTDQASAIKTKNVFI
AQNVASLQELGGSEKLLRVCLNLPYFLRYINRFQDAVLANSFFIMPATVADATAVRNGFH
SLVIDVTMALDTLSLPVLEPLNPSRLQDVTVLSLSCLYAGVSVATCMAILHVGSAQQVRT
GSTSSKEDDYESDAATIVQKCLEIYDMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLFL
ILNLSPTALADKGKEKDPLAALRVRDILSRTKEGVGSPKLGPGKGHQGFGVLSVILANHA
IKLLTSLFQDLQVEALHKGWETDGPPAALSIMAQSTSIQRIQRLIDSVPLMNLLLTLLST
SYRKACVLQRQRKGSMSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGQWFEETIS
PSKEKAAPPPPPPPPPLESSPRVKSPSKQAPGEKGNILASRKDPELFLGLASNILNFITS
SMLNSRNNFIRNYLSVSLSEHHMATLASIIKEVDKDGLKGSSDEEFAAALYHFNHSLVTS
DLQSPNLQNTLLQQLGVAPFSEGPWPLYIHPQSLSVLSRLLLIWQHKASAQGDPDVPECL
KVWDRFLSTMKQNALQGVVPNETEDLNVEHLQLLLLIFHNFTETGRRAILSLFVQIIQQL
SVNMDAQMRSVPLILARLLLIFDYLLHQYSKAPVYLFEQVQHNLLSPPFGWASGSQDSNS
RRATTPLYHGFKEVEENWSKHFSSDAVPQPRFYCVLSPEASEDDLNRLDSVACDVLFSKL
VKYDELYAALTALLAAGSQLDTVRRKENKNVTALEACALQYYFLILWRILGILPPSKTYI
NQLSMNSPEMSECDILHTLRWSSRLRISSYVNWIKDHLIKQGMKAEHASSLLELASTTKC
SSVKYDVEIVEEYFARQISSFCSIDCTTILQLHEIPSLQSIYTLDAAISKVQVSLDEHFS
KMAAETDPHKSSEITKNLLPATLQLIDTYASFTRAYLLQNFNEEGTTEKPSKEKLQGFAA
VLAIGSSRCKANTLGPTLVQNLPSSVQAVCESWNNINTNEFPNIGSWRNAFANDTIPSES
YISAVQAAHLGTLCSQSLPLAASLKHTLLSLVRLTGDLIVWSDEMNPPQVIRTLLPLLLE
SSTESVAEISSNSLERILGPAESDEFLARVYEKLITGCYNILANHADPNSGLDESILEEC
LQYLEKQLESSQARKAMEEFFSDSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEK
SPNPSLLHLCGSLAQLACVEPVRLQAWLTRMTTSPPKDSDQLDVIQENRQLLQLLTTYIV
RENSQVGEGVCAVLLGTLTPMATEMLANGDGTGFPELMVVMATLASAGQGAGHLQLHNAA
VDWLSRCKKYLSQKNVVEKLNANVMHGKHVMILECTCHIMSYLADVTNALSQSNGQGPSH
LSVDGEERAIEVDSDWVEELAVEEEDSQAEDSDEDSLCNKLCTFTITQKEFMNQHWYHCH
TCKMVDGVGVCTVCAKVCHKDHEISYAKYGSFFCDCGAKEDGSCLALVKRTPSSGMSSTM
KESAFQSEPRISESLVRHASTSSPADKAKVTISDGKVADEEKPKKSSLCRTVEGCREELQ
NQANFSFAPLVLDMLNFLMDAIQTNFQQASAVGSSSRAQQALSELHTVEKAVEMTDQLMV
PTLGSQEGAFENVRMNYSGDQGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGK
ITVLQLSALLKQADSSKRKLTLTRLASAPVPFTVLSLTGNPCKEDYLAVCGLKDCHVLTF
SSSGSVSDHLVLHPQLATGNFIIKAVWLPGSQTELAIVTADFVKIYDLSVDALSPTFYFL
LPSSKIRDVTFLFNEEGKNIIVIMSSAGYIYTQLMEEASSAQQGPFYVTNVLEINHEDLK
QDSNSQVAGGGVSVYYSHVLQMLFFSYCQGKSFAATISRTTLEVLQLFPINIKSSNGGSK
TSPALCQWSEVMNHPGLVCCVQQTTGVPLVVMVKPDTFLIQEIKTLPAKAKIQDMVAIRH
TACNEQQRTTMILLCEDGSLRIYMANVENTSYWLQPSLQPSSVISIMKPVRKRKTATITT
RTSSQVTFPIDFFEHNQQLTDVEFGGNDLLQVYNAQQIKHRLNSTGMYVANTKPGGFTIE
ISNNNSTMVMTGMRIQIGTQAIERAPSYIEIFGRTMQLNLSRSRWFDFPFTREEALQADK
KLNLFIGASVDPAGVTMIDAVKIYGKTKEQFGWPDEPPEEFPSASVSNICPSNLNQSNGT
GDSDSAAPATTSGTVLERLVVSSLEALESCFAVGPIIEKERNKNAAQELATLLLSLPAPA
SVQQQSKSLLASLHTSRSAYHSHKDQALLSKAVQCLNTSSKEGKDLDPEVFQRLVITARS
IAIMRPNNLVHFTESKLPQMETDCFFPRCACWSLGIVGILIGAPLETPSPEGMDEGKEPQ
KQLEGDCCSFITQLVNHFWKLHASKPKNAFLAPACLPGLTHIEATVNALVDIIHGYCTCE
LDCINTASKIYMQMLLCPDPAVSFSCKQALIRVLRPRNKRRHVTLPSSPRSNTPMGDKDD
DDDDDADEKMQSSGIPNGGHIRQESQEQSEVDHGDFEMVSESMVLETAENVNNGNPSPLE
ALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGLSGQAPSSS
SLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPADHGGSVGSESGGSAVDSVAGEHSV
SGRSSAYGDATAEGHPAGPGSVSSSTGAISTTTGHQEGDGSEGEGEGETEGDVHTSNRLH
MVRLMLLERLLQTLPQLRNVGGVRAIPYMQVILMLTTDLDGEDEKDKGALDNLLSQLIAE
LGMDKKDVSKKNERSALNEVHLVVMRLLSVFMSRTKSGSKSSICESSSLISSATAAALLS
SGAVDYCLHVLKSLLEYWKSQQNDEEPVATSQLLKPHTTSSPPDMSPFFLRQYVKGHAAD
VFEAYTQLLTEMVLRLPYQIKKIADTNSRIPPPVFDHSWFYFLSEYLMIQQTPFVRRQVR
KLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRASVVTASSGSALQYDTLIS
LMEHLKACAEIAAQRTINWQKFCIKDDSVLYFLLQVSFLVDEGVSPVLLQLLSCALCGSK
VLAALAASSGSSSASSSSAPVAASSGQATTQSKSSTKKSKKEEKEKEKDGETSGSQEDQL
CTALVNQLNKFADKETLIQFLRCFLLESNSSSVRWQAHCLTLHIYRNSSKSQQELLLDLM
WSIWPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTNHPNSN
IYNTLSGLVEFDGYYLESDPCLVCNNPEVPFCYIKLSSIKVDTRYTTTQQVVKLIGSHTI
SKVTVKIGDLKRTKMVRTINLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDL
PLPIVASNLMIEFADFYENYQASTETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSIN
YDEKDPFLCNACGFCKYARFDFMLYAKPCCAVDPIENEEDRKKAVSNINTLLDKADRVYH
QLMGHRPQLENLLCKVNEAAPEKPQDDSGTAGGISSTSASVNRYILQLAQEYCGDCKNSF
DELSKIIQKVFASRKELLEYDLQQREAATKSSRTSVQPTFTASQYRALSVLGCGHTSSTK
CYGCASAVTEHCITLLRALATNPALRHILVSQGLIRELFDYNLRRGAAAMREEVRQLMCL
LTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSCWELRLR
CALSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDVPVEALTTVKPYCNE
IHAQAQLWLKRDPKASYDAWKKCLPIRGMDGNGKAPSKSELRHLYLTEKYVWRWKQFLSR
RGKRTSPLDLKLGHNNWLRQVLFTPATQAARQAACTIVEALATIPSRKQQVLDLLTSYLD
ELSIAGECAAEYLALYQKLITSAHWKVYLAARGVLPYVGNLITKEIARLLALEEATLSTD
LQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDML
LEMLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFV
TLEKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVN
NKIISLDLPVAEVYKKVWCTTNEGEPMRIVYRMRGLLGDATEEFIESLDSTTDEEEDEEE
VYKMAGVMAQCGGLECMLNRLAGIRDFKQGRHLLTVLLKLFSYCVKVKVNRQQLVKLEMN
TLNVMLGTLNLALVAEQESKDSGGAAVAEQVLSIMEIILDESNAEPLSEDKGNLLLTGDK
DQLVMLLDQINSTFVRSNPSVLQGLLRIIPYLSFGEVEKMQILVERFKPYCNFDKYDEDH
SGDDKVFLDCFCKIAAGIKNNSNGHQLKDLILQKGITQNALDYMKKHIPSAKNLDADIWK
KFLSRPALPFILRLLRGLAIQHPGTQVLIGTDSIPNLHKLEQVSSDEGIGTLAENLLEAL
REHPDVNKKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTALLKQMEELI
EEPGLTCCICREGYKFQPTKVLGIYTFTKRVALEEMENKPRKQQGYSTVSHFNIVHYDCH
LAAVRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQRE
PTYQLNIHDIKLLFLRFAMEQSFSADTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREE
KNLQGFLEQPKEKWVESAFEVDGPHYFTVLALHILPPEQWRATRVEILRRLLVTSQARAV
APGGATRLTDKAVKDYSAYRSSLLFWALVDLIYNMFKKVPTSNTEGGWSCSLAEYIRHND
MPIYEAADKALKTFQEEFMPVETFSEFLDVAGLLSEITDPESFLKDLLNSVP |
|---|
| NT seq |
15639 nt +upstreamnt +downstreamnt
atggcgacgagcggcggcgaagaggcggcggcagcggctccagcgcccgggaccccggca
acgggggcggacacgaccccgggctgggaggtggctgtgcggcccctgctgtccgcgtcc
tactccgccttcgagatgaaggagttgccgcagctggtggcctcagtcatcgagagtgaa
tccgaaatcctgcaccatgagaagcagtacgagccattctactcatcttttgttgcactt
tccacacactatattacaacagtttgcagtctcattccgcggaaccaacttcagtcagtg
gcagcagcctgtaaagttctaattgagttttctctcctgcgtctggagaatccagatgag
gcttgtgctgtgtcccagaaacacttgattctcctaatcaagggcctatgcactggctgt
agccgactagatagaactgaaattatcacatttacagcaatgatgaaatccgccaagctg
ccccaaacagtgaagacactttcagacgtggaagatcagaaagagctggcctcaccagta
agccctgagttgaggcaaaaggaggtacagatgaattttttgaaccagctgacctcagtt
tttaaccctagaactgtagcatcacaacctatcagtacacagactctggtggaaggagaa
aatgatgagcagtcatctacagatcaagcctcagctatcaaaaccaagaatgtgttcata
gctcagaacgtggctagtcttcaagagcttggtggctcggagaagctgttgcgtgtgtgt
ttgaacctgccatatttcctacgctatatcaatcggttccaagatgcagtgttagctaat
tccttcttcataatgcctgcaacagtagcagatgccactgctgttcgtaatggctttcat
tcattggtgattgatgtaactatggcattggataccctttctctacctgtgttggaacct
ctcaatccttctcgtctacaagatgtgacagttctcagcctaagttgtctgtatgcaggt
gtgagtgtggcaacctgcatggccatcctccatgtgggtagtgcccagcaagtgcggact
gggtccacgagctccaaagaagatgactatgaaagtgatgcagctacaattgtccagaaa
tgtctcgaaatctatgacatgattggacaagcaatcagcagttctcgccgggctggtggt
gagcactatcagaatttccaattgctgggtgcttggtgcttgttaaacagccttttcctc
atactgaacctcagtcctactgcgttggctgataaggggaaagagaaggacccgctggct
gccctccgagtcagagacatcctttctcgtactaaagagggagtgggctcccctaaactg
gggcctggaaaagggcatcagggatttggggtactctcagtaatattggcaaaccatgcc
atcaaactgctaacgtctctctttcaagacctacaagtggaggcccttcacaagggttgg
gagacagatggcccccctgcagccttgagcattatggcccagagcacctccatacagagg
attcaacggctgattgactctgtcccactgatgaacctgctcttgacgttactttcaact
tcctacagaaaggcatgtgtcctgcagcggcaaaggaagggctccatgagcagcgatgcc
agcgcctccaccgactccaatacttactatgaggatgatttcagtagcacggaggaggac
agcagccaagacgatgacagtgagcctattttggggcaatggtttgaggagactatttct
cccagtaaagagaaagcagcacctccgcctcctcccccacctcctccactggaaagctct
cctcgggttaaaagccccagtaagcaggcccctggtgagaagggcaacattctggcgagt
cgtaaagatcctgagttgttcttaggtctggcttccaacattttgaacttcatcacctct
tccatgttgaactctcggaacaattttatccgaaactatctgagtgtatctctttcagaa
caccatatggccaccctagccagtatcatcaaggaggtggacaaagatggactcaagggt
tcatcagatgaagagtttgctgcagctctctatcacttcaaccactcactggtaacctct
gaccttcagtcacctaacctgcagaacacactgttgcagcagctaggagtggctcctttt
tctgagggcccttggcccttgtacattcaccctcaaagcctctctgtgctttcacgcctc
ctgctcatctggcaacataaagccagtgctcaaggtgaccctgacgtcccagaatgcctt
aaagtttgggacaggtttttgtctacaatgaagcagaatgccctgcaaggcgtggtgccc
aatgagacagaggatctgaatgtagaacacctgcagctgctcctcctcattttccacaat
ttcaccgagacaggccggcgggccatattgtcgctttttgtccagatcatccagcagttg
agcgtcaacatggatgctcagatgcgctccgtgccgcttatcttggctcgcctccttctc
atctttgattatctgcttcatcagtactccaaagcccctgtgtatctatttgagcaggta
cagcataacctgctaagtcctccctttgggtgggcaagtggatcccaggacagcaacagc
cgccgggcaaccactcctctctatcatggattcaaagaagtagaagaaaactggtctaag
catttctcatcagatgctgtcccacaacccagattctactgtgtcctgtccccagaagcc
tcagaggatgatttgaaccgacttgactctgtggcatgtgacgtccttttctccaagctt
gtcaagtatgatgagctttatgctgcactgacagccctgcttgcagctgggtcccagctt
gatacagttaggagaaaggaaaacaagaatgtaacagccttggaggcctgtgcccttcaa
tattacttcttgatactgtggaggatcctaggaattttaccaccatcaaagacttacatt
aaccagctatccatgaactcacctgagatgagcgaatgtgacatcttgcacactctgcga
tggtcttctcggctccggatcagctcctatgtcaactggataaaggatcaccttatcaaa
cagggaatgaaggctgagcatgctagctcacttctagaactggcatccaccactaagtgt
agctcagtgaaatatgatgttgaaatagtagaggaatacttcgctcgacagatctcatcc
ttctgtagtatcgactgtaccaccatcttgcagctgcatgaaattcccagtctgcagtcc
atctacacccttgatgctgccatctcaaaggtccaggtctctttggatgagcatttttct
aagatggctgctgagactgatcctcataagtcgtctgagattaccaagaacctacttcca
gccacgctacaactcattgacacctatgcatcgttcaccagagcctatttgctgcaaaac
tttaatgaagagggaacaactgagaaaccttccaaggagaaactgcaaggctttgctgct
gttttggctattggctctagtaggtgcaaggcaaatactctgggtccgacactggttcag
aatttgccatcgtcagtgcaggctgtgtgtgagtcctggaacaacatcaataccaatgaa
tttcccaatattggatcctggcgcaatgcctttgccaatgacaccatcccttcagagagt
tatattagtgcagtgcaggctgcacacctggggactctctgtagccaaagtctgcccctg
gctgcttccctgaagcacaccctcctctcactggtcaggttgactggagatcttattgtt
tggtcagatgagatgaacccaccacaggtaattcggaccctgctacctcttcttttggaa
tcaagcactgagagtgttgccgagatcagtagcaactccctggaacgcatcttgggccct
gctgagtctgatgagttcttggctcgtgtttatgagaagctgatcactggttgttacaac
attctggccaatcatgcagatcctaacagtggactggatgaatccatcctggaggaatgt
ctccagtacttggaaaagcagctggaaagtagccaggctcgtaaagctatggaggagttt
ttctctgacagtggagaacttgtacagatcatgatggcaacagccaatgagaacctctct
gctaaattctgtaaccgagttttgaaattcttcaccaaactcttccagctgactgagaag
agccctaacccaagcctgttgcatctctgtggctccctggcacagctggcctgtgtggag
cctgtgcgcctgcaggcctggctcacccgcatgactacatcacccccaaaagattctgat
cagctggatgtaattcaggagaatcggcagctgctgcagttactgaccacatacattgtt
cgggaaaacagccaagttggggaaggcgtgtgtgctgttcttctgggcaccctgactccc
atggcaacagagatgctggccaacggtgatgggactggcttccctgaacttatggttgtg
atggccactctggccagtgcaggtcaaggtgctggtcaccttcagcttcataatgctgct
gtggattggctgagcagatgcaagaaatacctgtcacagaagaatgtggttgaaaaactg
aatgccaatgtaatgcatggaaagcatgtgatgatcttggagtgcacatgccatatcatg
tcttacttggctgatgtcacgaatgccctgagccagagtaatggtcaaggcccaagtcat
ctctcagtggatggggaagagcgggccattgaagtagactcagactgggtggaggagttg
gcggtggaagaggaagattcccaggctgaggattcagatgaagattctctttgcaataaa
ctctgcacttttacgatcacacagaaagaattcatgaaccagcattggtaccactgtcac
acctgcaaaatggtggatggcgtgggtgtctgcacagtgtgtgctaaggtgtgccacaag
gatcatgagatttcctatgccaagtatggatccttcttctgtgactgtggagccaaggaa
gatggcagctgtttggctctggtgaagagaactcctagcagtggcatgagctctaccatg
aaagagtcagcatttcagagtgaacccaggatttcagagagtctagtgcgtcatgccagc
acctcctccccagctgacaaagccaaggttaccatcagtgatggaaaggttgctgacgaa
gagaagcccaagaagagcagcctctgccgcacagtagagggctgccgggaggaattacag
aaccaggccaatttctccttcgctcctctcgtgttagacatgcttaatttccttatggat
gccattcagaccaacttccagcaagcttcagccgtcgggagcagcagccgtgctcagcaa
gccctcagtgagctacacacagtggagaaggcagtggagatgacagaccagctgatggtt
cccaccttaggctcccaggaaggtgcctttgagaatgtgcggatgaattacagtggagac
cagggccagaccatccggcagctgatcagcgctcatgtgctcaggcgggtggctatgtgt
gtgctctcctctccccatggacgccgccaacatttggctgtcagccatgagaagggcaag
atcactgttctgcagctctctgcactcctgaagcaagcggattccagcaaaaggaagtta
actctgacccgcttggcttctgccccagttccttttactgtgttgagcctcacaggaaat
ccctgcaaggaagactacttggcggtttgtgggctaaaggactgccatgtgctcaccttt
agtagctcaggctctgtttcggatcacttggttttgcaccctcagttggcaacggggaac
ttcatcatcaaagccgtgtggttacctggttcacagaccgagttggcaattgtcactgca
gactttgttaagatttatgacctgtctgttgatgccttgagtccaaccttctactttctc
ctgccaagctcaaagataagagatgttaccttccttttcaatgaggagggaaagaacatc
attgttataatgtcttcggctgggtacatctatactcagcttatggaagaggccagcagt
gcccagcagggacccttctatgtcactaatgtgttggaaatcaatcatgaggacctgaag
caggacagtaacagccaggtggcaggtggcggtgtgtccgtgtactactcccacgtgttg
cagatgttgttcttcagctattgtcaaggcaaatcatttgcagccaccatcagcaggaca
accctggaggtgttgcaactcttccccatcaacatcaaaagttccaatggtggcagtaag
acttctcctgctctttgccagtggtctgaggtgatgaaccaccctggcttggtgtgctgt
gtccagcaaactacaggggtgccgctggtagttatggtgaaaccagacacttttcttatc
caggagattaagactcttcctgctaaagcaaagatccaagacatggttgctattaggcat
acggcctgcaatgagcagcagcggacaacaatgattctgctgtgtgaggacggcagcctg
cgcatttacatggccaacgtggagaacacctcctactggctgcagccatccctgcagccc
agcagtgtcatcagcatcatgaagcctgttcgaaagcgcaaaacagctacaatcacaacc
cgcacgtctagccaggtgactttccccattgacttttttgaacacaaccagcagctgaca
gatgtggagtttggtggtaatgacctcctgcaggtctataatgcacaacagataaaacac
cggctgaattccactggcatgtatgtggccaacaccaagcccggaggcttcaccattgag
atcagtaacaacaatagcactatggtgatgacaggcatgcggatccagattgggactcaa
gcaatagaacgggccccatcatatattgagatcttcggcagaactatgcagctcaacctg
agtcgctcacgctggtttgactttcccttcaccagagaagaagccctgcaggctgataag
aagctgaacctcttcattggggcctcggtggatccagcaggtgtcaccatgatagatgct
gtaaaaatttatggcaagactaaggagcagtttggctggcctgatgaacccccagaagaa
ttcccttctgcctctgtcagcaacatctgcccttcaaatctgaaccagagcaacggcact
ggagatagcgactcagctgcccccgctacgaccagtggaactgtcctggagaggctggtt
gtgagttctttagaagccctggaaagctgttttgccgttggcccaatcatcgagaaggag
agaaacaagaatgctgctcaggagctggccactttgctgttgtccctgccagcacctgcc
agtgtccagcagcagtccaagagccttctggccagcctgcacaccagccgctcggcctac
cacagccacaaggatcaggccttgctgagcaaagctgtgcagtgtctcaacacatctagc
aaagaaggcaaggatttggaccctgaggtgttccagaggctagtgatcacagctcgctcc
attgccatcatgcgccccaacaaccttgtccactttacggagtcaaagctgccccagatg
gaaacagactgtttttttcctagatgtgcctgctggagtctagggatagttggcatattg
attggggccccacttgaaactccctccccagaaggaatggatgaagggaaggaaccacag
aagcagttggaaggagattgctgtagtttcatcacccagcttgtgaaccacttctggaaa
ctccatgcatccaaacccaagaatgccttcttggcacctgcctgccttccaggactaact
catattgaagctactgtcaatgctctggtggacatcatccatggctactgtacctgtgag
ctggattgtattaacacagcatccaagatctacatgcagatgctcttgtgtcctgatcct
gctgtgagcttctcttgtaaacaagctctaattcgagtcctaaggcccaggaacaaacgg
agacatgtgactttaccctcttcccctcgaagcaacactccaatgggagacaaggatgat
gatgacgatgatgacgcagatgagaaaatgcagtcatcagggattccgaatggtggtcac
atccgtcaggaaagccaggaacagagtgaggtggaccatggagattttgagatggtgtct
gagtcgatggtcctggagacagctgaaaatgtcaacaatggcaacccctctcccctggag
gccctgctggcaggcgcagagggcttcccccccatgctggacatcccgcctgatgcagat
gacgagaccatggttgaactagccattgccctgagcctgcagcaggaccaacaaggcagc
agcagcagtgccctgggcctgcagagcctgggactgtccggccaggcacccagctcttcc
tctctggacgcaggaaccctctctgacaccacagcatcagctccagcctcagacgacgag
ggcagtacagcagcgacagatggttctacccttcggacctctcctgctgaccacggtggt
agtgtgggctcggagagcgggggcagtgcagtggactcagtggctggcgagcacagtgtg
tctggccggagcagtgcttatggtgatgccacagctgaggggcatccggctggaccagga
agtgtcagctcaagcactggagccatcagcaccaccactgggcaccaggagggagatggc
tccgagggagaaggagaaggagaaactgaaggagatgtccacactagcaacaggctgcac
atggtccgtctaatgctgttggagagattactgcagaccctgcctcaattacgaaatgtt
ggcggtgtccgggccatcccgtacatgcaggtcattctaatgctcactacagatctggat
ggagaagatgagaaagacaagggggccctagacaacctgctctcccagcttattgctgag
ttgggtatggataaaaaggatgtctccaagaagaatgagcgcagcgccctgaatgaagtc
catctggtagtaatgagactcctgagtgtcttcatgtcccgcaccaaatctggatccaag
tcttccatatgtgagtcatcttccctcatctccagtgccacagcagcagctctactgagc
tctggggcggtggactactgcctgcacgtgctgaaatcactgctggaatattggaagagc
caacagaatgatgaggagcctgtggctaccagccagttgctgaaaccacatactacctcc
tccccacctgacatgagcccattctttctccgccagtatgtgaagggtcatgctgctgat
gtgtttgaggcctatactcagcttctaacagaaatggtactgaggcttccataccaaatc
aaaaagattgctgacaccaattctcgaatcccacctcctgtctttgaccattcgtggttt
tactttctctccgagtacctaatgatccagcagactccatttgtgcgccgtcaagtccgc
aaacttctgctcttcatctgtggatccaaagagaagtaccgccagctccgggatttgcac
accctggactctcacgtgcgtgggatcaagaagctgctagaagagcaggggatattcctc
agggcaagtgtggttacagccagctcaggctccgccttgcaatatgacacactcatcagc
ctgatggagcacttgaaagcctgtgcagagattgccgcccagcgaaccatcaactggcag
aaattctgcatcaaagacgactccgtcctgtacttcctcctccaagtcagtttcctcgtg
gatgagggcgtgtccccagtgctgctgcaactgctctcctgtgctctgtgcggcagcaaa
gtgctcgctgcactggcagcctcttcgggatcctccagtgcttcttcctcctcagcccct
gtggctgccagttctggacaagccacaacacagtccaagtcttccactaaaaagagcaag
aaagaagaaaaagaaaaggagaaagatggtgagacctctggcagccaggaggaccagctg
tgcacagctctggtgaaccagctgaacaaatttgccgataaggaaaccctgatccagttc
ctgcgttgtttcctgttagagtccaattcttcctcggtgcgctggcaggcccactgtctg
acgctgcacatctacagaaattccagcaaatctcaacaggagctcctgctagatctgatg
tggtccatctggccagaactcccagcctatggtcgtaaggctgcccagtttgtggaccta
ctagggtatttctccctgaaaactccacaaacggagaagaagttgaaggagtattcacag
aaagctgtggagattctgcggactcaaaaccatattcttaccaaccaccccaactcgaac
atttataacactttgtctggcttagtggagtttgatggctattacctggagagtgatccc
tgcctggtgtgtaataacccagaagtaccgttctgttatatcaagctgtcttccattaaa
gtggacacccggtacaccaccacccagcaggttgtgaagctcattggcagtcacaccatc
agcaaagtgacagtgaaaatcggggatctgaaacggaccaagatggtgcggaccatcaac
ctttattataacaaccgaaccgtgcaggccatcgtggagttgaaaaacaagccagctcgc
tggcacaaagccaagaaggttcagctgacccctgggcagacagaggtgaagattgacctg
ccgttgcccattgtggcctccaatctgatgattgagtttgcagacttctatgaaaactac
caggcctccacagagaccctgcagtgccctcgctgtagtgcctcggtccctgccaaccca
ggagtctgtggcaactgtggagagaatgtgtaccagtgtcacaaatgcagatccatcaac
tacgatgaaaaggatcccttcctctgcaatgcctgtggcttctgtaaatatgcccgcttc
gacttcatgctctatgccaagccttgctgtgcagtggatcccattgagaatgaagaagac
cggaagaaggctgtatccaacatcaatacacttttggacaaagctgatcgagtgtatcat
cagctgatgggacaccggccacagctggagaacctgctctgcaaagtgaatgaggcagct
ccagaaaagccacaggatgactcaggaacagcagggggcatcagctccacttccgccagt
gtgaatcgttatatcctgcagttggctcaggagtattgtggagactgcaagaactctttt
gatgaactctccaaaatcatccagaaagtctttgcttcacgcaaagagttgttggaatat
gacctacagcagagggaagcagccactaaatcatcccggacctctgtgcagcccacattc
actgccagccagtaccgtgccttatccgtcctgggctgtggccacacatcctccaccaag
tgctatggctgtgcctcggctgtcacagaacattgtatcacactacttcgggccctggcc
accaacccagccttgaggcacatccttgtctcccagggccttatccgggagctctttgat
tataatcttcgccgaggggctgcggccatgcgggaggaggtccgccagctcatgtgcctc
ctaactcgagacaacccagaagccactcagcagatgaatgacctgattattggcaaggtc
tccacagccctgaagggccactgggccaaccccgatctggcaagtagcctgcagtatgaa
atgctgctgctgacggattctatctccaaggaggacagctgctgggagctccggttacgc
tgtgctctcagccttttcctcatggctgtgaacattaagactcctgtggtggttgagaac
attaccctcatgtgcctgaggatcttgcagaagctgataaaaccacctgctcccactagc
aagaagaacaaggatgtccccgtcgaggccctcaccacggtgaagccatactgcaatgag
atccatgcccaggctcaactgtggctcaagagagaccccaaggcatcctatgatgcctgg
aagaagtgtcttcctatcagagggatggatggcaatgggaaagcccccagcaaatcagag
ctccgccatctctatttgactgagaagtatgtgtggaggtggaaacagttcctgagtcgt
cgggggaagaggacctcccccttggatctcaaactggggcataacaactggctgcgacaa
gtgcttttcactccagcaacacaggccgcacggcaggcagcctgtaccattgtggaagct
ctagccaccattcccagccgcaagcagcaggtcctggacctgcttaccagttacctggat
gagctgagcatagctggggagtgtgcagctgagtacctggctctctaccagaagctcatc
acttccgcgcactggaaagtctacttggcagctcggggagtcctaccctatgtgggcaac
ctcatcaccaaggaaatagctcgtctgctggccctggaggaggctaccctgagtactgat
ctgcagcagggttatgcccttaaaagtctcacaggccttctctcctcctttgttgaggtg
gagtccatcaaaagacattttaaaagtcgcttggtgggtactgtgctgaatggatacctg
tgcttgcggaagctggtggtgcagaggaccaagctgattgatgagacacaggacatgctg
ctggagatgctggaggacatgaccacaggtacagaatcagaaaccaaggccttcatggct
gtgtgcattgagacagccaagcgctacaatctggatgactaccggaccccggtgttcatc
ttcgagaggctctgcagcatcatttatcctgaggagaatgaagtcactgagttcttcgtg
accctggagaaggatccccaacaagaagacttcttacagggcaggatgcctgggaacccg
tatagcagcaatgagccaggcatcgggccgctgatgagggatataaagaacaagatttgc
caggactgtgacttagtggccctcctggaagatgacagtggcatggagcttctagtgaac
aataaaatcattagtttggaccttcctgtggctgaagtttacaagaaagtctggtgtacc
acgaatgagggagagcccatgaggattgtttatcgtatgcgggggctgctgggtgatgcc
acagaggagttcattgagtccctggactctactacagatgaagaagaagatgaagaagaa
gtgtataaaatggctggtgtgatggcccagtgtgggggcctggaatgcatgcttaacaga
ctcgcagggatcagagatttcaagcagggacgccaccttctaacagtgctactgaaattg
ttcagttactgcgtgaaggtgaaagtcaaccggcagcaactggtcaagctggaaatgaac
accttgaacgtcatgctggggaccctaaacctggcccttgtagctgaacaagaaagcaag
gacagtgggggcgcagctgtggctgagcaggtgcttagcatcatggagatcattctagat
gagtccaatgctgagcccctgagtgaggacaagggcaacctcctcctgacaggtgacaag
gatcaactggtgatgctcttggaccagatcaacagcacctttgttcgctccaaccccagt
gtgctccagggcctgcttcgcatcatcccgtacctttcctttggagaggtggagaaaatg
cagatcttggtggagcgattcaaaccatactgcaactttgataaatatgatgaagatcac
agtggtgatgataaagtcttcctggactgcttctgtaaaatagctgctggcatcaagaac
aacagcaatgggcaccagctgaaggatctgattctccagaaggggatcacccagaatgca
cttgactacatgaaaaagcacatccctagcgccaagaatttggatgccgacatctggaaa
aagtttttgtctcgcccagccttgccgtttatcctaaggctgcttcggggcctggccatc
cagcaccctggcacccaggttctaattggaactgattccatcccgaacctgcataagctg
gagcaggtgtccagtgatgagggcattgggaccctggcagagaacctgctggaagccctg
cgggaacaccctgacgtaaacaagaagattgacgcagcccgcagggagacccgggcggag
aagaagcgcatggccatggcgatgaggcagaaggccctgggcaccctgggcatgacgaca
aatgaaaagggccaggtcgtgaccaagacagcgctcctgaagcagatggaagagctgatc
gaggagcctggcctcacttgctgcatctgcagggagggatacaagttccagcccacaaag
gtcctgggcatttataccttcacgaagcgggtagccttggaggagatggagaataagccc
cggaaacagcagggctacagcaccgtgtcccacttcaacattgtgcactacgactgccat
ctggctgccgtcaggttggctcgaggccgggaagagtgggagagtgccgccctgcagaat
gccaacaccaagtgcaatgggctccttccggtctgggggcctcatgtccctgaatcagct
tttgccacttgcttggcaagacacaacacttacctccaggaatgtacaggccagcgggag
cccacgtaccagctcaacatccacgacatcaaactgctcttcctgcgcttcgccatggag
cagtcgttcagcgcagacactggcgggggcggccgtgagagcaacatccacctgatcccg
tacatcattcacactgtgctttacgtcctgaacacaacccgagcaacttcccgagaagag
aagaacctccaaggctttctggaacagcccaaggagaagtgggtggagagtgcctttgaa
gtggacgggccccactatttcacagtcttggcccttcatatcctgccccctgagcagtgg
agagccacacgtgtggaaatcttgcggaggctgttggtgacctcgcaggcccgggcagtg
gctccaggtggagccaccaggctgacagataaggcagtgaaggactattccgcttaccgt
tcttcccttctcttttgggccctcgtcgatctcatttacaacatgtttaagaaggtgcct
accagtaacacagagggaggctggtcctgctctctcgctgagtacatccgccacaacgac
atgcccatctacgaagctgccgacaaagccctgaaaaccttccaggaggagttcatgccg
gtggagaccttctcagagttccttgatgtggctggtcttttatcagaaatcaccgatcca
gagagcttcctgaaggacctgttgaactcagtcccctga |
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