Pongo abelii (Sumatran orangutan): 100462446
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Entry
100462446 CDS
T01416
Symbol
KDR
Name
(RefSeq) vascular endothelial growth factor receptor 2
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon01521
EGFR tyrosine kinase inhibitor resistance
pon04010
MAPK signaling pathway
pon04014
Ras signaling pathway
pon04015
Rap1 signaling pathway
pon04020
Calcium signaling pathway
pon04151
PI3K-Akt signaling pathway
pon04370
VEGF signaling pathway
pon04510
Focal adhesion
pon05205
Proteoglycans in cancer
pon05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100462446 (KDR)
04014 Ras signaling pathway
100462446 (KDR)
04015 Rap1 signaling pathway
100462446 (KDR)
04370 VEGF signaling pathway
100462446 (KDR)
04020 Calcium signaling pathway
100462446 (KDR)
04151 PI3K-Akt signaling pathway
100462446 (KDR)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100462446 (KDR)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100462446 (KDR)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
100462446 (KDR)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100462446 (KDR)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pon01001
]
100462446 (KDR)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pon04090
]
100462446 (KDR)
Enzymes [BR:
pon01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100462446 (KDR)
Protein kinases [BR:
pon01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
100462446 (KDR)
CD molecules [BR:
pon04090
]
Proteins
100462446 (KDR)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
VEGFR-2_TMD
V-set
C2-set_2
Ig_4
BppU_N
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100462446
NCBI-ProteinID:
XP_002814831
Ensembl:
ENSPPYG00000014765
UniProt:
H2PDE2
LinkDB
All DBs
Position
3:63911566..63958681
Genome browser
AA seq
1356 aa
AA seq
DB search
MESKVLLAVALWLCVGTRAAFVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLD
WLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQD
YRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWD
SKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGE
KLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRS
DQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPVKYLGYPPP
EIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVP
PQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECPNEPSQAVSVTNPY
PCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQVANVSALYKCEAVNKVGRGE
RVISFHVTRGPEITLQPDMQPTEQESVSLWCAADRSTFENLTWYKLGPQPLPIHMGELPT
PVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLT
VLERVAPMITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNR
NLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWL
LLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVN
LLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLK
RRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLA
SRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDR
VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTML
DCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVS
CMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDS
GMVLASEELKTLEDRTKLAPSFSGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYS
SEEAELLKLIEIGVQTGSTAQILQPDSGTTLSSPPV
NT seq
4071 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggtgctgctggccgtcgccctgtggctctgcgtggggacccgggccgcc
tttgtgggtttgcctagtgtttctcttgatctgcccaggctcagcatacaaaaagacata
cttacaattaaggctaatacaactcttcaaattacttgcaggggacagagggacttggac
tggctttggcccaataatcagagtggcagtgagcaaagggtggaggtgactgagtgcagc
gatggcctcttctgtaagacactcacaattccaaaagtgatcggaaatgacactggagcc
tacaagtgcttctaccgggaaactgacttggcctcggtcatttatgtctatgttcaagat
tacagatctccatttattgcttctgttagtgaccaacatggagtcgtgtacattacagag
aacaaaaacaaaactgtggtgattccatgtctcgggtccatttcaaatctcaacgtgtca
ctttgtgcaaggtacccagaaaagagatttgttcctgatggaaacagaatttcctgggac
agcaagaagggctttactattcccagctacatgatcagctatgctggcatggtcttctgt
gaagcaaaaattaatgatgaaagttaccagtctattatgtacatagttgtcgttgtaggg
tataggatttatgatgtggttctgagtccgtctcacggaattgaactatctgttggagaa
aagcttgtcttaaattgtacagcaagaactgaactaaatgtggggattgacttcaactgg
gaatacccttcttcgaagcatcagcataagaaacttgtaaaccgagacctaaaaacccag
tctgggagtgagatgaagaaatttttgagcaccttaactatagatggtgtaacccggagt
gaccaaggattgtacacctgtgcagcgtccagtgggctgatgaccaagaagaacagcact
tttgtcagggtccatgaaaaaccttttgttgcttttggaagtggcatggaatctctggtg
gaagccacggtgggggagcgtgtcagaatccctgtgaagtaccttggttacccaccccca
gaaataaaatggtataaaaatggaataccccttgagtccaatcacacaattaaagcgggg
catgtactgacgattatggaagtgagtgaaagagacacagggaattacactgtcatcctt
accaatcccatttcaaaggagaagcagagccacgtggtctctctggttgtgtatgtccca
ccccagattggtgagaaatcgctgatctctcctgtggattcctaccagtatggcaccact
caaacgctgacgtgtacggtctatgccattcctcccccgcatcacatccactggtattgg
cagttggaggaagagtgccccaacgagcccagccaagctgtctcagtgacaaacccatac
ccttgtgaagaatggagaagtgtggaggactttcagggaggaaataaaattgaagtcaat
aaaaatcaatttgctctaattgaaggaaaaaacaaaactgtaagtacccttgttatccaa
gtggcaaatgtgtcagctttgtacaaatgtgaagcggtcaacaaagtcgggagaggagag
agggtgatctccttccacgtgaccaggggtcctgaaattactttgcaacctgacatgcag
cccactgagcaggagagcgtgtctttgtggtgcgctgcagacagatctacgtttgagaac
ctcacatggtacaagcttggcccacagcctctgccaatccacatgggagagttgcccaca
cctgtttgcaagaacttggatactctttggaaattgaatgccaccatgttctctaatagc
acaaatgacattttgatcatggagcttaagaatgcatccttgcaggaccaaggagactat
gtctgccttgctcaagacaggaagaccaagaaaagacattgcgtggtcagacagctcaca
gtcctagagcgtgtggcacccatgatcacaggaaacctggagaatcagacgacaagtatt
ggggaaagcatcgaagtctcatgcacggcatctgggaatccccctccacagatcatgtgg
tttaaagataatgagacccttgtagaagactcaggcattgtattgaaggatgggaaccgg
aacctcactatccgcagagtgaggaaggaggacgaaggcctctacacctgccaggcatgc
agtgttcttggctgtgcaaaagtggaggcattcttcataatagaaggtgcccaggaaaag
acgaacttggaaatcattattctagtaggcacagcggtgattgccatgttcttctggcta
cttcttgtcatcatcctacggaccgttaagcgggctaatggaggggaactgaagacaggc
tacttgtccatcgtcatggatccagatgaactcccattggacgaacattgtgaacgactg
ccttatgatgccagcaaatgggaattccccagagaccggctgaagctaggtaagcctctt
ggccgtggtgcctttggccaagtgattgaagcagatgcctttggaattgacaagacagca
acttgcaggacagtagctgtcaaaatgttgaaagaaggagcaacacacagtgagcatcga
gccctcatgtctgaactcaagatcctcattcatattggtcaccatctcaatgtggtcaac
cttctaggtgcctgtaccaagccaggagggccactcatggtgattgtggaattctgcaaa
tttggaaacctatccacttacctgaggagcaagagaaatgaatttgtcccctacaagacc
aaaggggcacgattccgtcaagggaaagactacgttggagcaatccctgtggatctgaaa
cggcgcttggacagcatcaccagtagccagagctcagctagctctggatttgtggaggag
aagtccctcagtgatgtagaagaagaggaagctcctgaagatctgtataaggacttcctg
accttggagcatctcatctgttacagcttccaagtggctaagggcatggagttcttggca
tcgcgaaagtgtatccacagggacctggcggcacgaaatatcctcttatcggagaagaac
gtggttaaaatctgtgactttggcttggcccgggatatttataaagatccagattatgtc
agaaaaggagatgctcgcctccctttgaaatggatggccccagaaacaatttttgacaga
gtgtacacaatccagagtgacgtctggtcttttggtgttttgctgtgggaaatattttcc
ttaggtgcttctccatatcctggggtaaagattgatgaagaattttgtaggcgactgaaa
gaaggaactagaatgagggcccccgattatactacaccagaaatgtaccagaccatgctg
gactgctggcacggggagcccagtcagagacccacgttttcagagttggtggaacatttg
ggaaatctcttgcaagctaatgctcagcaggatggcaaagactacattgttcttccgata
tcagagactttgagcatggaagaggattctggactctctctgcctacctcacctgtttcc
tgtatggaggaggaggaagtatgtgaccccaaattccattatgacaacacagcaggaatc
agtcagtatctgcagaacagtaagcgaaagagcaggcctgtgagtgtaaaaacatttgaa
gatatcccattagaagaaccagaagtaaaagtaatcccagatgacaaccagacggacagt
ggtatggttcttgcctcagaagagctgaaaactttggaagacagaaccaaattagctcca
tcttttagtggaatggtgcccagcaaaagcagggagtctgtggcatctgaaggctcaaac
cagacaagcggctaccagtccggatatcactccgatgacacagacaccactgtgtactcc
agtgaggaagcagaacttttaaagctgatagagattggagtgcaaaccggcagcacagcc
cagattctccagcctgactcggggaccacactgagctctcctcctgtttaa
DBGET
integrated database retrieval system
