Plecotus auritus (brown big-eared bat): 308239067
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Entry
308239067 CDS
T11911
Symbol
IGF1R, AC0HY7_005900
Name
(RefSeq) insulin-like growth factor 1 receptor isoform 1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pots Plecotus auritus (brown big-eared bat)
Pathway
pots01521
EGFR tyrosine kinase inhibitor resistance
pots01522
Endocrine resistance
pots04010
MAPK signaling pathway
pots04014
Ras signaling pathway
pots04015
Rap1 signaling pathway
pots04066
HIF-1 signaling pathway
pots04068
FoxO signaling pathway
pots04081
Hormone signaling
pots04114
Oocyte meiosis
pots04140
Autophagy - animal
pots04144
Endocytosis
pots04150
mTOR signaling pathway
pots04151
PI3K-Akt signaling pathway
pots04152
AMPK signaling pathway
pots04211
Longevity regulating pathway
pots04213
Longevity regulating pathway - multiple species
pots04510
Focal adhesion
pots04518
Integrin signaling
pots04519
Cadherin signaling
pots04520
Adherens junction
pots04550
Signaling pathways regulating pluripotency of stem cells
pots04730
Long-term depression
pots04913
Ovarian steroidogenesis
pots04914
Progesterone-mediated oocyte maturation
pots05200
Pathways in cancer
pots05202
Transcriptional misregulation in cancer
pots05205
Proteoglycans in cancer
pots05214
Glioma
pots05215
Prostate cancer
pots05218
Melanoma
pots05224
Breast cancer
pots05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pots00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
308239067 (IGF1R)
04014 Ras signaling pathway
308239067 (IGF1R)
04015 Rap1 signaling pathway
308239067 (IGF1R)
04066 HIF-1 signaling pathway
308239067 (IGF1R)
04068 FoxO signaling pathway
308239067 (IGF1R)
04151 PI3K-Akt signaling pathway
308239067 (IGF1R)
04152 AMPK signaling pathway
308239067 (IGF1R)
04150 mTOR signaling pathway
308239067 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
308239067 (IGF1R)
04518 Integrin signaling
308239067 (IGF1R)
04519 Cadherin signaling
308239067 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
308239067 (IGF1R)
04140 Autophagy - animal
308239067 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
308239067 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
308239067 (IGF1R)
04520 Adherens junction
308239067 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
308239067 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
308239067 (IGF1R)
04914 Progesterone-mediated oocyte maturation
308239067 (IGF1R)
09156 Nervous system
04730 Long-term depression
308239067 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
308239067 (IGF1R)
04213 Longevity regulating pathway - multiple species
308239067 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
308239067 (IGF1R)
05202 Transcriptional misregulation in cancer
308239067 (IGF1R)
05205 Proteoglycans in cancer
308239067 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
308239067 (IGF1R)
05214 Glioma
308239067 (IGF1R)
05218 Melanoma
308239067 (IGF1R)
05215 Prostate cancer
308239067 (IGF1R)
05224 Breast cancer
308239067 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
308239067 (IGF1R)
01522 Endocrine resistance
308239067 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pots01001
]
308239067 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pots04090
]
308239067 (IGF1R)
Enzymes [BR:
pots01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
308239067 (IGF1R)
Protein kinases [BR:
pots01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
308239067 (IGF1R)
CD molecules [BR:
pots04090
]
Proteins
308239067 (IGF1R)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Insulin_TMD
Fn3_Dep-1_6th
Kinase-like
Motif
Other DBs
NCBI-GeneID:
308239067
NCBI-ProteinID:
XP_080507762
LinkDB
All DBs
Position
15:5361506..5494295
Genome browser
AA seq
1413 aa
AA seq
DB search
MKSALGGGSLASLWALLFFTATLAFWPTSGEICGPGIDIRNDFQQLKRLENCTVIEGYLH
ILLISKGDDYRSYRFPKLTVITEYLLLFRVAGLESIGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLRNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYVVGNKSPKECGD
VCPGALEGKPTCERTTINNEYNYRCWTQDHCQKTCPSACGKRACTENNECCHPECLGGCT
APDDEAACVACKHYYHEGVCVTDCPPDTYRFEGWRCVDRDFCATIPNADSFEMEGFVIHD
GECMQECPSGFIRNDSLSMYCVPCEGPCPKICEEDKGTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYIKIRHSHALVSLSFFKSLRQILGEDQLEGNYSF
YVLDNQNLQQLWDWDNHNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDMLHFTSTNTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPYKNVTEYDG
QDACGSNSWNMVDVDLPANKDMQPGILLHGLKPWTQYAIYVKAVTLTMVDNDHIRGAKSE
ILYIRTNASVPSIPLDVISASNSSSQLIVKWNPPSLPNGNLSYYIVRWQQQPQDAYLYRH
NYCSKDKLPVRKYTDGTFDIEEVTENPKTESCSSPKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVGQISNTTLSGRSRNSTVADAFNSTDSDDMETEHPFFES
RVDKKERTVISNLKPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPITW
ELKPDNTIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQDYRKHGGAKLQKLSPGN
YTARIQATSLSGNGSWTEPVFFYVQDKAAYDSYAHLVIALPIAIVLIVCGLAVTLYLIHR
KRNRMGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMNRELGQGSFGMVYEGVAKGVV
KDEPETRVAIKTVNESASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELM
PRGDLKSYLRSLRPEIENHPILSPPTLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCM
VAEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVL
WEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMQVCWHFNPKMRPSFLDI
IGSIKDELEPGFIEVSFYYSDENKPPDTEELDLDPDHLECVPLDPSASCSSLPLPERHCH
HHHDGRERYCHHHHEGRERYCHRHHEGRERYCPHHRHHEGRERERHCPHRPENGLGHRVL
IYRASFDERQAYAHMNGGRKNERPVPLPQSSTC
NT seq
4242 nt
NT seq
+upstream
nt +downstream
nt
atgaagtccgctctcggaggagggtccctggcctcgctgtgggcgctgctgtttttcacc
gccacgctcgccttctggccgacgagcggagaaatctgcggccccggcatcgacatccgc
aacgacttccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctgcac
atcctgctcatctccaagggcgacgactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcatcggcgacctgttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcggcctgcgcaacctgcgcaacatcacccgcggcgcc
atccgcatcgagaagaacgccgacctctgctacctgtccaccgtggactggtccctcatc
ctcgacgccgtgtccaacaactacgtggtggggaacaagtcccccaaggagtgcggggac
gtgtgcccgggggccctggaggggaagcccacctgtgagaggaccaccatcaacaacgag
tacaactatcgctgctggacccaggaccactgccagaaaacctgcccgagcgcgtgcggg
aagcgggcgtgcacggagaacaacgagtgctgccaccccgagtgcctgggcggctgcacg
gcccccgacgacgaggcggcctgcgtggcctgcaagcactactaccacgagggcgtttgc
gtgaccgactgccccccggacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaccatccccaacgccgacagcttcgagatggagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctccggcttcatccgcaacgacagcctgagcatgtac
tgcgtcccctgcgaagggccttgccccaaaatctgtgaggaggacaaggggacgaagact
attgactcggtgacctcggctcagatgctccagggctgcaccatcttcaagggcaacctt
ctcattaacatccgcaggggcaataacatcgcctcggaactggagaacttcatggggctc
atcgaggtggtcacaggctacatcaagatccgccactcgcacgcgctggtctccctgtcc
ttcttcaaaagcctccgccagatcctgggagaggaccagctggaggggaattactccttc
tacgtcctggacaaccagaacctgcagcagctgtgggactgggacaaccacaacctgacc
atcaaggccggcaagatgtacttcgccttcaaccccaaactgtgcgtgtccgagatctac
cgcatggaggaggtgaccgggacgaaagggcgccagagcaaaggggacatcaacacccgg
aacaacggggagagggcctcctgtgagagcgacatgctgcacttcacctccaccaacacc
tggaagaaccgcatcatcatcacgtggcaccggtaccggcccccggactacagggacctc
atcagcttcaccgtctactacaaggaagcgccctacaagaacgtcaccgagtacgacggc
caggacgcctgcggctccaacagctggaacatggtggacgtggacctgcccgccaacaag
gacatgcagcccggcatcctcctgcacggcctgaagccctggacgcagtacgccatctac
gtgaaggccgtgaccctgaccatggtggacaacgaccacatccgcggggccaagagcgag
atcctgtacatccgcaccaacgcctcggtgccttccatccccctggacgtcatctcggcc
tccaactcctcctcgcagctgatcgtcaagtggaacccgccctccctgcccaacgggaac
ctgagctactacatcgtgcgctggcagcagcagccccaggacgcctacctgtaccggcac
aactactgctccaaagacaagctccccgtgcggaagtacacagacggcaccttcgacatc
gaggaggtgacggagaaccccaagaccgagtcgtgcagcagccccaaggggccttgctgc
gcgtgtcccaaaaccgaggccgagaagcaggcggagaaggaggaggccgagtaccgcaag
gtcttcgagaacttcctgcacaactccatcttcgtgcccaggcccgagaggaagcgcagg
gacgtggggcagatttccaacaccaccctctccggccggagcaggaacagcacggtggcg
gacgccttcaacagcaccgactcggacgacatggagacggagcaccccttcttcgagagc
agggtggacaagaaggagaggaccgtcatttccaacctgaaacccttcaccctctaccgc
atcgatatccacagctgcaaccacgaggccgagaagctgggctgcagcgcctccaacttc
gtctttgcgaggaccatgcctgcagagggagcagatgacattcctgggccgatcacctgg
gagctgaagcctgacaacaccatcttcttaaagtggccggaacctgagaatcccaacggc
ctgatcctcatgtatgagataaaatacgggtcacaggtcgaggaccagcgggagtgcgtg
tcccggcaggactaccggaagcacggaggggccaagctgcagaagctcagcccggggaac
tacacggcccgcatccaggccacctctctgtctgggaacgggtcctggacggagcccgtg
ttcttctacgtccaggacaaagcggcgtatgacagttacgcccacctggtcatcgcgctg
cccatcgccatcgtgctgatcgtctgcgggctggccgtcacgctgtacctcatccacagg
aagcgtaatcggatggggaacggagtgctgtacgcgtctgtgaacccggagtatttcagc
gcggccgacgtgtacgtgcccgacgagtgggaggtggcccgggagaagatcaccatgaac
cgggagttgggccagggctccttcggcatggtgtacgagggtgtggccaagggcgtggtc
aaggatgagccggaaaccagggtggccatcaagacagtcaacgagtccgccagcatgcgg
gagcggatcgagttcctcaacgaggcctcggtgatgaaggagttcaactgtcaccatgtg
gtgcgtttgctgggtgtggtgtcccagggccagccgaccctggtcatcatggagctcatg
ccccggggtgacctcaagagttacctcaggtctctgaggccggaaattgagaatcacccc
atcctctcaccgccgaccctcagcaagatgatccagatggccggggagattgcggacggc
atggcgtacctcaacgccaacaagttcgtccatcgagaccttgctgcccggaactgcatg
gtggctgaagatctgaccgtcaagatcggagatttcggcatgactcgcgacatctacgag
accgactattaccggaagggcgggaaggggctgctgcctgtgcgctggatgtcccccgag
tccctcaaggacggcgtgttcaccacccactccgatgtctggtcctttggcgttgtgctc
tgggagatcgccacgctggccgagcagccctaccagggcctctccaacgaacaggtcctg
cgcttcgtcatggagggcggcctcctggacaaacccgacaactgccccgacatgctgttc
gagctcatgcaggtgtgctggcacttcaaccccaagatgcggccttccttcctggacatc
atcggcagcatcaaggacgagctggagcccggcttcatcgaggtctccttctactacagc
gacgagaacaagccgcccgacaccgaggagctggacctggaccccgaccacctggagtgc
gtgcccctggacccctcggcctcctgctcctccctgccgctgcccgagcgccactgccac
caccaccacgacggccgcgagcgctactgccaccaccaccacgagggccgcgagcgctac
tgccaccgccaccacgagggccgcgagcgctactgcccgcaccaccgccaccacgagggc
cgcgagcgcgagcgccactgcccgcaccggcccgagaacggcctgggccaccgcgtgctg
atctaccgggccagcttcgacgagaggcaggcttacgcgcacatgaatggggggcgcaag
aacgagaggcccgtgcctctgccgcagtcctccacctgctga
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integrated database retrieval system
